Major Research Project Theoretical Chemistry (C, E, S)

Course

URL study guide

https://studiegids.vu.nl/en/courses/2024-2025/XM_0029

Course Objective

The aim is to obtain experience in scientific research including the design and execution of computational experiments and to critically interpret and reflect on these results. The project will be conducted within the field of theoretical (bio)chemistry in one of the following settings: - University or Academic hospital - Research institute - Company The internship can be performed either within the Netherlands or abroad.

Course Content

The specific content of the project depends on the associated supervisor(s), available projects at the host/location and the timing of the internship, but generally deals with quantum chemical methods, including Density Functional Theory (DFT). DFT calculations are used to gain insights in chemical interactions, like reaction mechanisms that lead to the synthesis of drugs, or the interactions of (drug) molecules with DNA and/or proteins. Attention will be paid to setting up new research/experiments, using state-of-the-art computational techniques, analyzing computational results and keeping adequate documentation.

Teaching Methods

Literature review, formulating a research question, conducting experiments, keeping adequate documentation, analyzing data, reporting on results in progress/group meetings, in a written thesis and final presentation within the research group.

Method of Assessment

Academic attitude, execution, oral presentation, and written thesis

Literature

Starting literature will be provided by the supervisor. The first 1-2weeks of the traineeship will be spent on literature reading andpreparation for the project.

Target Audience

C,E,S variants of mDDS-Computer-aided Drug Design

Custom Course Registration

The number of internal (VU) internship positions is limited. Candidates are selected based on their motivation letter and CV in an application procedure. See the canvas site “Master Drug Discovery Sciences” for more information regarding this application procedure. Be aware that selection procedures exist for most external positions as well. Before the start of the project, an internship agreement has to be signed by all involved parties, and the project proposal has to be approved by the VU supervisor via the online internship management system. See the “Master Drug Discovery Sciences Internship manual” for more information on the rules and regulations regarding internships. If, after reading the manual, you still have questions regarding the process related to internships, admission, approval, etc., please contact the internship coordinator via [email protected].

Additional Information

The standard length of a major internship for the Communication, Education, or Societal variant, is 24 EC (4 months), which can be extended to 36 EC (6 months). Make sure you discuss your personal education plan with your master coordinator well in advance. See the “Master Drug Discovery Sciences Internship manual” for more information (rules, regulations, tips, etc.) on the internship process. This manual can be found on the canvas community “Master Drug Discovery Sciences”.

Entry Requirements

Entry requirements with respect to attained courses and number of credits apply. See the Education and Examination regulations and the internship manual Drug Discovery Sciences. For questions, consult the internship coordinator well in advance ([email protected]).
Academic year1/09/2431/08/25
Course level24.00 EC

Language of Tuition

  • English

Study type

  • Master