https://studiegids.vu.nl/en/courses/2025-2026/X_422589Below is provided a point-to-point list of the learning goals of the class that can be used as guidelines for the exams. At the end of this course, the students will:know the basic concepts of physics (in particular mechanics, statistical physics and thermodynamics), physical chemistry and mathematics to describe quantitatively biology on the cellular and molecular level.use these basic concepts to derive quantitative and predictive models that give a deeper insight into living systems.implement and compare different models to analyze quantitatively experimental data obtained from state-of-the-art microscopy approaches and formulate new biological models.Basic concepts in thermodynamics and statistical physics to describe biological process such as protein-ligand binding, and polymer conformation.Basic concepts in mechanics to describe how biological beam responds to stress and strain. Combining statistical physics and mechanics to describe semi-flexible polymer such as DNA.Basic concepts of hydrodynamics to understand how liquid flows in the channels, and how dimensions impact the nature of the flow and the motion of objects in liquid.Derivation of the law of diffusion from a macroscopic and microscopic perspective and its application to describe small molecule motion, protein-ligand association kinetics, and molecular motors translocation.Lectures (4h per week) & Tutorials (2h per week)Written exam (60% of final grade) + written tests (2x, 10% of final grade each) on part of the course contents + tutorial assessments (20% of final grade).Phillips, R., Kondev, J., and Theriot, J., Physical Biology of the Cell. 2nd Edition New York: Garland Science, 2012 (ISBN 0815344503). Chapter 1 to 13 (except 9 and 11). (1st edition is also fine)3N, 3MNW mi-BB, 3WN, 3SThis course is part of the Minors Biomedische Beeldvorming and Basics of Bioinformatics and Systems Biology. Mathematics: Calculus & Mathematische Methoden (or comparable) Physics: basics of mechanics & thermodynamicsMathematics: Calculus & Mathematische Methoden (or comparable)Physics: basics of mechanics & thermodynamics