Additional file 13 of Distinct cell type-specific protein signatures in GRN and MAPT genetic subtypes of frontotemporal dementia

  • Suzanne Miedema (Creator)
  • M.O. Mol (Creator)
  • Frank Koopmans (Creator)
  • David C. Hondius (Creator)
  • Pim van Nierop (Creator)
  • Kevin Menden (Creator)
  • Christina F. de Veij Mestdagh (University of Groningen, VU University Medical Center) (Creator)
  • J. van Rooij (Creator)
  • Andrea B. Ganz (Amsterdam UMC) (Creator)
  • Iryna Paliukhovich (Creator)
  • Shamiram Melhem (Creator)
  • Ka Wan Li (Creator)
  • Henne Holstege (Creator)
  • Patrizia Rizzu (Creator)
  • Ronald van Kesteren (Creator)
  • J.C. van Swieten (Creator)
  • Peter Heutink (Creator)
  • Guus Smit (Creator)

Dataset / Software

Description

Additional file 13 Overview of unique proteins detected and quantified within temporal cortical tissues for AD and unique proteins detected and quantified within temporal cortical tissues for both AD and the FTD-MAPT subtype. Proteins were selected using quality filtering on peptide level (q ≤10-3 in at least 50% of samples per group, i.e. NDC or AD). For every protein, the raw fold change and raw p-value are given for the statistical comparison between NDC and AD, and NDC and FTD-MAPT. In addition, columns are included which note whether a protein has passed statistical multiple testing comparison (q < 0.05) and whether differential protein expression is in a similar direction in AD and FTD-MAPT.
Date made available2022
PublisherFigshare

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