Additional file 3 of Distinct cell type-specific protein signatures in GRN and MAPT genetic subtypes of frontotemporal dementia

Additional file 3 Lists of unique proteins detected and quantified within frontal and temporal cortical tissues for the RiMOD-FTD genetic subtypes. Proteins were selected using quality filtering on peptide level (q ≤10-3 in at least 50% of samples per group, i.e. NDC or FTD). For every protein, the raw fold change, raw p-value, multiple comparison corrected q-value, and effect size (d) are given for the statistical comparison between NDC and FTD subtype. In addition, columns are included which note whether a protein has passed statistical testing (either p < 0.05 or q < 0.05). Furthermore, the differential expression of several well-known neurodegeneration (ND)-related proteins in frontal cortical FTD-GRN vs NDC and temporal cortical FTD-MAPT vs NDC are highlighted. -; not detected within study cohort.