Amsterdam Neuroscience - Complex Trait Genetics

Research Output 2010 2020

2020

Bayesian mixture regression analysis for regulation of Pluripotency in ES cells

Aflakparast, M., Geeven, G. & De Gunst, M. C. M., 2 Jan 2020, In : BMC Bioinformatics. 21, p. 1-13 13 p., 3.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Regression Analysis
Regression analysis
Genes
Gene
Transcription Factors

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., Beekman, A. T. F., Jansen, R., Milaneschi, Y., Smit, J. H., W J H Penninx, B. & Posthuma, D., 23 Jan 2020, In : Molecular Psychiatry.

Research output: Contribution to JournalArticleAcademicpeer-review

Major Depressive Disorder
Genome
Wounds and Injuries
Genes
Depression

Polygenic Risk Scores for Developmental Disorders, Neuromotor Functioning During Infancy, and Autistic Traits in Childhood

Serdarevic, F., Tiemeier, H., Jansen, P. R., Alemany, S., Xerxa, Y., Neumann, A., Robinson, E., Hillegers, M. H. J., Verhulst, F. C. & Ghassabian, A., 15 Jan 2020, In : Biological Psychiatry. 87, 2, p. 132-138 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Attention Deficit Disorder with Hyperactivity
Genetic Predisposition to Disease
Genome-Wide Association Study
Child Development
Netherlands
2019

10kin1day: A bottom-up neuroimaging initiative

Van Den Heuvel, M. P., Scholtens, L. H., Van Der Burgh, H. K., Agosta, F., Alloza, C., Arango, C., Auyeung, B., Baron-Cohen, S., Basaia, S., Benders, M. J. N. L., Beyer, F., Booij, L., Braun, K. P. J., Filho, G. B., Cahn, W., Cannon, D. M., Chaim-Avancini, T. M., Chan, S. S. M., Chen, E. Y. H., Crespo-Facorro, B. & 94 othersCrone, E. A., Dannlowski, U., De Zwarte, S. M. C., Dietsche, B., Donohoe, G., Plessis, S. D., Durston, S., Díaz-Caneja, C. M., Díaz-Zuluaga, A. M., Emsley, R., Filippi, M., Frodl, T., Gorges, M., Graff, B., Grotegerd, D., Gąsecki, D., Hall, J. M., Holleran, L., Holt, R., Hopman, H. J., Jansen, A., Janssen, J., Jodzio, K., Jäncke, L., Kaleda, V. G., Kassubek, J., Masouleh, S. K., Kircher, T., Koevoets, M. G. J. C., Kostic, V. S., Krug, A., Lawrie, S. M., Lebedeva, I. S., Lee, E. H. M., Lett, T. A., Lewis, S. J. G., Liem, F., Lombardo, M. V., Lopez-Jaramillo, C., Margulies, D. S., Markett, S., Marques, P., Martínez-Zalacaín, I., McDonald, C., McIntosh, A. M., McPhilemy, G., Meinert, S. L., Menchón, J. M., Montag, C., Moreira, P. S., Morgado, P., Mothersill, D. O., Mérillat, S., Müller, H. P., Nabulsi, L., Najt, P., Narkiewicz, K., Naumczyk, P., Oranje, B., De la Foz, V. O. G., Peper, J. S., Pineda, J. A., Rasser, P. E., Redlich, R., Repple, J., Reuter, M., Rosa, P. G. P., Ruigrok, A. N. V., Sabisz, A., Schall, U., Seedat, S., Serpa, M. H., Skouras, S., Soriano-Mas, C., Sousa, N., Szurowska, E., Tomyshev, A. S., Tordesillas-Gutierrez, D., Valk, S. L., Van Den Berg, L. H., Van Erp, T. G. M., Van Haren, N. E. M., Van Leeuwen, J. M. C., Villringer, A., Vinkers, C. H., Vollmar, C., Waller, L., Walter, H., Whalley, H. C., Witkowska, M., Witte, A. V., Zanetti, M. V., Zhang, R. & De Lange, S. C., 9 May 2019, In : Frontiers in Neurology. 10, MAY, p. 1-7 7 p., 425.

Research output: Contribution to JournalReview articleAcademicpeer-review

Open Access
Connectome
Neuroimaging
Brain
Neurosciences
Research Personnel

A cross-disorder connectome landscape of brain dysconnectivity

van den Heuvel, M. P. & Sporns, O., 1 Jul 2019, In : Nature Reviews Neuroscience. 20, 7, p. 435-446 12 p.

Research output: Contribution to JournalReview articleAcademicpeer-review

Connectome
Brain Diseases
Brain
Nervous System Diseases
Psychiatry
homeostasis
insulin
methylation
Methylation
DNA Methylation

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis

Liu, J., Carnero-Montoro, E., van Dongen, J., Lent, S., Nedeljkovic, I., Ligthart, S., Tsai, P. C., Martin, T. C., Mandaviya, P. R., Jansen, R., Peters, M. J., Duijts, L., Jaddoe, V. W. V., Tiemeier, H., Felix, J. F., Willemsen, G., de Geus, E. J. C., Chu, A. Y., Levy, D., Hwang, S. J. & 37 othersBressler, J., Gondalia, R., Salfati, E. L., Herder, C., Hidalgo, B. A., Tanaka, T., Moore, A. Z., Lemaitre, R. N., Jhun, M. A., Smith, J. A., Sotoodehnia, N., Bandinelli, S., Ferrucci, L., Arnett, D. K., Grallert, H., Assimes, T. L., Hou, L., Baccarelli, A., Whitsel, E. A., van Dijk, K. W., Amin, N., Uitterlinden, A. G., Sijbrands, E. J. G., Franco, O. H., Dehghan, A., Spector, T. D., Dupuis, J., Hivert, M. F., Rotter, J. I., Meigs, J. B., Pankow, J. S., van Meurs, J. B. J., Isaacs, A., Boomsma, D. I., Bell, J. T., Demirkan, A. & van Duijn, C. M., 13 Jun 2019, In : Nature Communications. 10, p. 1-11 11 p., 2581.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
homeostasis
insulin
methylation
Methylation
DNA Methylation
Intelligence
Publication Bias
Brain
Social Class
Population

Are Bigger Brains Smarter? Evidence From a Large-Scale Preregistered Study

Nave, G., Jung, W. H., Karlsson Linnér, R., Kable, J. W. & Koellinger, P. D., Jan 2019, In : Psychological science. 30, 1, p. 43-54 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Intelligence
Publication Bias
Brain
Social Class
Population

A spectrum of routing strategies for brain networks

Avena-Koenigsberger, A., Yan, X., Kolchinsky, A., van den Heuvel, M. P., Hagmann, P. & Sporns, O., 8 Mar 2019, In : PLoS Computational Biology. 15, 3, p. 1-24 24 p., e1006833.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
routing
animal communication
brain
Brain
Routing

Association of Genetic Liability to Psychotic Experiences with Neuropsychotic Disorders and Traits

Legge, S. E., Jones, H. J., Kendall, K. M., Pardiñas, A. F., Menzies, G., Bracher-Smith, M., Escott-Price, V., Rees, E., Davis, K. A. S., Hotopf, M., Savage, J. E., Posthuma, D., Holmans, P., Kirov, G., Owen, M. J., O'Donovan, M. C., Zammit, S. & Walters, J. T. R., 1 Dec 2019, In : JAMA Psychiatry. 76, 12, p. 1256-1265 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Schizophrenia
Genome-Wide Association Study
Major Depressive Disorder
Odds Ratio
Genetic Loci

Association of Whole-Genome and NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M. G., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. JC., W J H Penninx, B., Jansen, R. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jan 2019, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Major Depressive Disorder
Anisotropy
Genome
Radiation
Diffusion Tensor Imaging

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

23Andme Research Team & HUNT All-In Psychiatry, Feb 2019, In : Nature Genetics. 51, 2, p. 237-244 8 p.

Research output: Contribution to JournalLetterAcademicpeer-review

Tobacco Use
Alcohols
Tobacco Use Cessation
Genetic Association Studies
Synaptic Transmission

Author Correction: GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability (Nature Neuroscience, (2018), 21, 9, (1161-1170), 10.1038/s41593-018-0206-1)

The 23andMe Research Team, The Substance Use Disorders Working Group of the Psychiatric Genomics Consortium & International Cannabis Consortium, 1 Jul 2019, In : Nature Neuroscience. 22, 7, p. 1196 1 p.

Research output: Contribution to JournalComment / Letter to the editorAcademic

Open Access
File
Genetic Loci
Genome-Wide Association Study
Cannabis
Neurosciences
Psychiatry

Author Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG

23Andme Research Team & Social Science Genetic Association Consortium, Aug 2019, In : Nature Genetics. 51, 8, p. 1295-1295 1 p.

Research output: Contribution to JournalComment / Letter to the editorAcademic

Open Access

Biological Characteristics of Connection-Wise Resting-State Functional Connectivity Strength

Pijnenburg, R., Scholtens, L. H., Mantini, D., Vanduffel, W., Barrett, L. F. & van den Heuvel, M. P., 21 Jan 2019, In : Cerebral Cortex.

Research output: Contribution to JournalArticleAcademicpeer-review

Strychnine
Macaca
Magnetic Resonance Imaging
Brain
gamma-Aminobutyric Acid

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Derks, E. M., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M., Peyrot, W. J., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., W J H Penninx, B. & Sullivan, P., 11 Nov 2019, In : Molecular Psychiatry.

Research output: Contribution to JournalArticleAcademicpeer-review

Bipolar Disorder
Psychiatry
Schizophrenia
Depression
Major Depressive Disorder

Blood cell-derived human tissue Transglutaminase (TG2) in multiple sclerosis: Implications for the pathogenesis and clinical outcome

Sestito, C., 2019, 136 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File

Brain connectivity alterations in early psychosis: from clinical to neuroimaging staging

Griffa, A., Baumann, P. S., Klauser, P., Mullier, E., Cleusix, M., Jenni, R., van den Heuvel, M. P., Do, K. Q., Conus, P. & Hagmann, P., 4 Feb 2019, In : Translational Psychiatry. 9, 1, p. 1-10 10 p., 62.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Neuroimaging
Psychotic Disorders
Brain
Discriminant Analysis
Connectome

Cell Replacement Therapy Improves Pathological Hallmarks in a Mouse Model of Leukodystrophy Vanishing White Matter

Dooves, S., Leferink, P. S., Krabbenborg, S., Breeuwsma, N., Bots, S., Hillen, A. E. J., Jacobs, G., van der Knaap, M. S. & Heine, V. M., 5 Mar 2019, In : Stem cell reports. 12, 3, p. 441-450 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Leukoencephalopathies
Cell- and Tissue-Based Therapy
Neuroglia
Stem Cells
Stem cells

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M., Peyrot, W. J., Posthuma, D. & Willemsen, G., 5 Aug 2019, In : Biological Psychiatry. p. 1-12 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
HLA Antigens
Haplotypes
Alleles
Depression
Major Histocompatibility Complex

Common Polygenic Variations for Psychiatric Disorders and Cognition in Relation to Brain Morphology in the General Pediatric Population

Alemany, S., Jansen, P. R., Muetzel, R. L., Marques, N., El Marroun, H., Jaddoe, V. W. V., Polderman, T. J. C., Tiemeier, H., Posthuma, D. & White, T., 9 Jan 2019, (Accepted/In press) In : Journal of the American Academy of Child and Adolescent Psychiatry. p. 1-8 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Cognition Disorders
Attention Deficit Disorder with Hyperactivity
Psychiatry
Pediatrics
Intelligence
Open Access
Connectome
Macaca
Neural Pathways
Brain
Cluster Analysis

Connectome-Based Patterns of First-Episode Medication-Naïve Patients With Schizophrenia

Cui, L-B., Wei, Y., Xi, Y-B., Griffa, A., De Lange, S. C., Kahn, R. S., Yin, H. & Van den Heuvel, M. P., 24 Oct 2019, In : Schizophrenia Bulletin. 45, 6, p. 1291-1299 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Connectome
Schizophrenia
Organizations
Functional Neuroimaging
Brain

Cross-sectional and longitudinal assessment of the upper cervical spinal cord in motor neuron disease

van der Burgh, H. K., Westeneng, H. J., Meier, J. M., van Es, M. A., Veldink, J. H., Hendrikse, J., van den Heuvel, M. P. & van den Berg, L. H., 2019, In : NeuroImage: Clinical. 24, p. 1-12 12 p., 101984.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Motor Neuron Disease
Amyotrophic Lateral Sclerosis
Motor Neurons
Nerve Degeneration
Brain
Open Access
Data Integration
Bayesian inference
Regression Model
Variable Selection
Regression

Decoding Genetic Associations of Human Complex Traits

Watanabe, K., 2019, 212 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File

Discordant attributes of structural and functional brain connectivity in a two-layer multiplex network

Lim, S., Radicchi, F., van den Heuvel, M. P. & Sporns, O., 27 Feb 2019, In : Scientific Reports. 9, 1, p. 1-13 13 p., 2885.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Connectome
Brain
Magnetic Resonance Imaging

Discovering the genetic architecture of the mind: (Epi-)genome-wide association studies on human psychology and behavior

Karlsson Linnér, R., 2019, 170 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File

Disentangling polygenic associations between attention-deficit/hyperactivity disorder, educational attainment, literacy and language

iPSYCH-Broad-PGC ADHD Consortium, 1 Dec 2019, In : Translational Psychiatry. 9, 1, 35.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Aptitude
Attention Deficit Disorder with Hyperactivity
Language
Reading
Intelligence

Evolutionary expansion of connectivity between multimodal association areas in the human brain compared with chimpanzees

Ardesch, D. J., Scholtens, L. H., Li, L., Preuss, T. M., Rilling, J. K. & van den Heuvel, M. P., 2 Apr 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 14, p. 7101-7106 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Pan troglodytes
Brain
Connectome
Language
Diffusion Magnetic Resonance Imaging

Evolutionary modifications in human brain connectivity associated with schizophrenia

van den Heuvel, M. P., Scholtens, L. H., de Lange, S. C., Pijnenburg, R., Cahn, W., van Haren, N. E. M., Sommer, I. E., Bozzali, M., Koch, K., Boks, M. P., Repple, J., Pievani, M., Li, L., Preuss, T. M. & Rilling, J. K., 1 Dec 2019, In : Brain : a journal of neurology. 142, 12, p. 3991-4002 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Schizophrenia
Brain
Pan troglodytes
Connectome
Brain Diseases

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

iPSYCH-GEMS Schizophrenia Working Group, CommonMind Consortium & The Schizophrenia Working Group of the PsyUniversity of Copenhagenchiatric Genomics Consortium, 25 Mar 2019, In : Nature Genetics. 51, 4, p. 659–674 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Genome-Wide Association Study
Prefrontal Cortex
Schizophrenia
Tay-Sachs Disease
Gene Expression

Gene-set analysis: unraveling genetic mysteries using the power of molten rock

de Leeuw, C. A., 2019, 256 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File

Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls-Corrigendum

Pettersson, E., Lichtenstein, P., Larsson, H., Song, J., Agrawal, A., Borglum, A. D., Bulik, C. M., Daly, M. J., Davis, L. K., Demontis, D., Edenberg, H. J., Grove, J., Gelernter, J., Neale, B. M., Pardinãs, A. F., Stahl, E., Walters, J. T. R., Walters, R., Sullivan, P. F., Posthuma, D. & 1 othersPolderman, T. J. C., Jan 2019, In : Psychological Medicine. 49, 2, p. 351-351 1 p.

Research output: Contribution to JournalLetterAcademicpeer-review

Open Access
File

Genetic mapping and evolutionary analysis of human-expanded cognitive networks

Wei, Y., de Lange, S. C., Scholtens, L. H., Watanabe, K., Ardesch, D. J., Jansen, P. R., Savage, J. E., Li, L., Preuss, T. M., Rilling, J. K., Posthuma, D. & van den Heuvel, M. P., 24 Oct 2019, In : Nature Communications. 10, 1, p. 4839

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Brain
Genes
genes
brain
Genetic Loci

Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways

The 23andMe Research Team, Mar 2019, In : Nature Genetics. 51, 3, p. 394-403 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Sleep Initiation and Maintenance Disorders
Genome
Sleep
Genes
Neurons

Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence

Smeland, O. B., Bahrami, S., Frei, O., Shadrin, A., O’Connell, K., Savage, J., Watanabe, K., Krull, F., Bettella, F., Steen, N. E., Ueland, T., Posthuma, D., Djurovic, S., Dale, A. M. & Andreassen, O. A., 4 Jan 2019, In : Molecular Psychiatry. p. 1-10 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Intelligence
Bipolar Disorder
Schizophrenia
Genome
Alleles
Genetic Loci
Genome-Wide Association Study
Single Nucleotide Polymorphism
Computational Biology
Synaptic Transmission

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Social Science Genetic Association Consortium, 23and Me Research Team, eQTLGen Consortium & International Cannabis Consortium, 1 Feb 2019, In : Nature Genetics. 51, 2, p. 245-257 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Genetic Loci
Genome-Wide Association Study
Single Nucleotide Polymorphism
Computational Biology
Synaptic Transmission

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLGen Consortium, BIOS Consortium & the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, 1 May 2019, In : Nature Genetics. 51, 5, p. 793-803 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Genome-Wide Association Study
Bipolar Disorder
Genome
Neurotransmitter Transport Proteins
Endocannabinoids

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk

Jansen, I. E., Savage, J. E., Watanabe, K., Bryois, J., Williams, D. M., Steinberg, S., Sealock, J., Karlsson, I. K., Hägg, S., Athanasiu, L., Voyle, N., Proitsi, P., Witoelar, A., Stringer, S., Aarsland, D., Almdahl, I. S., Andersen, F., Bergh, S., Bettella, F., Bjornsson, S. & 33 othersBrækhus, A., Bråthen, G., de Leeuw, C., Desikan, R. S., Djurovic, S., Dumitrescu, L., Fladby, T., Hohman, T. J., Jonsson, P. V., Kiddle, S. J., Rongve, A., Saltvedt, I., Sando, S. B., Selbæk, G., Shoai, M., Skene, N. G., Snaedal, J., Stordal, E., Ulstein, I. D., Wang, Y., White, L. R., Hardy, J., Hjerling-Leffler, J., Sullivan, P. F., van der Flier, W. M., Dobson, R., Davis, L. K., Stefansson, H., Stefansson, K., Pedersen, N. L., Ripke, S., Andreassen, O. A. & Posthuma, D., 1 Mar 2019, In : Nature Genetics. 51, 3, p. 404-413 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Meta-Analysis
Alzheimer Disease
Genome
Proxy
Genes

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee, P. H., Anttila, V., Won, H., Feng, Y., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M., Grotzinger, A. D., Posthuma, D., Derks, E. M., op Landt Slof, M. C. T., Boomsma, D. I., de Geus, E. J. C., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., W J H Penninx, B., Cath, D. C. & 11 othersDenys, D., Santangelo, S., Scharf, J. M., Stein, M. B., Thornton, L. M., Walters, J. T. R., Wray, N. R., Geschwind, D. H., Neale, B. M., Kendler, K. S. & Smoller, J. W., 12 Dec 2019, In : Cell. 179, 7, p. 1469-1482.e11

Research output: Contribution to JournalArticleAcademicpeer-review

Psychiatry
Genes
Tourette Syndrome
Obsessive-Compulsive Disorder
Anorexia Nervosa

Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits

Grotzinger, A. D., Rhemtulla, M., de Vlaming, R., Ritchie, S. J., Mallard, T. T., Hill, W. D., Ip, H. F., Marioni, R. E., McIntosh, A. M., Deary, I. J., Koellinger, P. D., Harden, K. P., Nivard, M. G. & Tucker-Drob, E. M., 1 Mar 2019, In : Nature Human Behaviour.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-Wide Association Study
Single Nucleotide Polymorphism
Phenotype
Genetic Models
Psychiatry

Gradients of structure–function tethering across neocortex

Vázquez-Rodríguez, B., Suárez, L. E., Markello, R. D., Shafiei, G., Paquola, C., Hagmann, P., Van Den Heuvel, M. P., Bernhardt, B. C., Spreng, R. N. & Misic, B., 15 Oct 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 42, p. 21219-21227 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Neocortex
Brain
Population

High amyloid burden is associated with fewer specific words during spontaneous speech in individuals with subjective cognitive decline

Verfaillie, S. C. J., Witteman, J., Slot, R. E. R., Pruis, I. J., Vermaat, L. E. W., Prins, N. D., Schiller, N. O., van de Wiel, M., Scheltens, P., van Berckel, B. N. M., van der Flier, W. M. & Sikkes, S. A. M., Aug 2019, In : Neuropsychologia. 131, p. 184-192 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Amyloid
Alzheimer Disease
Neuropsychological Tests
Linguistics
Theft

Identification of common genetic risk variants for autism spectrum disorder

Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, BUPGEN, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23Andme Research Team, Mar 2019, In : Nature Genetics. 51, 3, p. 431-444 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Genome-Wide Association Study
Phenotype
Sample Size
Meta-Analysis
Autism Spectrum Disorder

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 11 Jun 2019, In : Nature Communications. 10, p. 1-18 18 p., 2548.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
methylation
DNA Methylation
Fetal Blood
blood
Blood

Interaction of schizophrenia polygenic risk and cortisol level on pre-adolescent brain structure

Bolhuis, K., Tiemeier, H., Jansen, P. R., Muetzel, R. L., Neumann, A., Hillegers, M. H. J., van den Akker, E. T. L., van Rossum, E. F. C., Jaddoe, V. W. V., Vernooij, M. W., White, T. & Kushner, S. A., Mar 2019, In : Psychoneuroendocrinology. 101, p. 295-303 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Hydrocortisone
Schizophrenia
Brain
Hair
Neuroimaging

Interrogating the genetic determinants of Tourette's syndrome and other tiC disorders through genome-wide association studies

Tourette Association of America International Consortium for Genetics, Gilles de la Tourette GWAS Replication Initiative, Tourette International Collaborative Genetics Study & Psychiatric Genomics Consortium Tourette Syndrome Working Group, 1 Mar 2019, In : American Journal of Psychiatry. 176, 3, p. 217-227 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

File
Tic Disorders
Tourette Syndrome
Genome-Wide Association Study
Tics
Meta-Analysis