Research Output 1972 2019

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2019

A Genetic Investigation of the Well-Being Spectrum

Baselmans, B. M. L., van de Weijer, M. P., Abdellaoui, A., Vink, J. M., Hottenga, J. J., Willemsen, G., Nivard, M. G., de Geus, E. J. C., Boomsma, D. I. & Bartels, M., 15 May 2019, In : Behavior Genetics. 49, 3, p. 286-297 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Phenotype
phenotype
Loneliness
Health
genetic correlation

A Genetic Investigation of the Well-Being Spectrum (vol 49, pg 286, 2019)

Baselmans, B. M. L., van de Weijer, M. P., Abdellaoui, A., Vink, J. M., Hottenga, J. J., Willemsen, G., Nivard, M. G., de Geus, E. J. C., Boomsma, D. I. & Bartels, M., May 2019, In : Behavior Genetics. 49, 3, p. 298-298

Research output: Contribution to JournalArticleAcademicpeer-review

Aggressive behaviour in childhood and adolescence: the role of smoking during pregnancy, evidence from four twin cohorts in the EU-ACTION consortium

Malanchini, M., Smith-Woolley, E., Ayorech, Z., Rimfeld, K., Krapohl, E., Vuoksimaa, E., Korhonen, T., Bartels, M., van Beijsterveldt, T. C. E. M., Rose, R. J., Lundström, S., Anckarsäter, H., Kaprio, J., Lichtenstein, P., Boomsma, D. I. & Plomin, R., Mar 2019, In : Psychological Medicine. 49, 4, p. 646-654 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Smoking
Aggression
Mothers
Pregnancy
Twin Studies

A linear mixed-model approach to study multivariate gene-environment interactions

BIOS Consortium, 't Hoen, P. A., van Meurs, J. B. J., Isaacs, A., Jansen, R., Franke, L., Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J., Van Greevenbroek, M. J., Stehouwer, C. D. A., van der Kallen, C. J. H., Schalkwijk, C. G., Wijmenga, C., Zhernakova, A., Tigchelaar, E. F., Slagboom, P. E., Beekman, M., Deelen, J. & 30 othersvan Heemst, D., Veldink, J. H., van den Berg, L. H., van Duijn, C. M., Hofman, B. A., Uitterlinden, A. G., Jhamai, P. M., Verbiest, M., Suchiman, H. E. D., Verkerk, M., van der Breggen, R., van Rooij, J., Lakenberg, N., Mei, H., van Iterson, M., van Galen, M., Bot, J., van’t Hof, P., Deelen, P., Nooren, I., Moed, M., Vermaat, M., Zhernakova, D. V., Luijk, R., Jan Bonder, M., van Dijk, F., Arindrarto, W., Kielbasa, P. S. M., Swertz, M. A. & van Zwet, E. W., Jan 2019, In : Nature Genetics. 51, 1, p. 180-186 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Gene-Environment Interaction
Linear Models
Body Mass Index
Genotype
Diet

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis

Liu, J., Carnero-Montoro, E., van Dongen, J., Lent, S., Nedeljkovic, I., Ligthart, S., Tsai, P-C., Martin, T. C., Mandaviya, P. R., Jansen, R., Peters, M. J., Duijts, L., Jaddoe, V. W. V., Tiemeier, H., Felix, J. F., Willemsen, G., de Geus, E. J. C., Chu, A. Y., Levy, D., Hwang, S-J. & 37 othersBressler, J., Gondalia, R., Salfati, E. L., Herder, C., Hidalgo, B. A., Tanaka, T., Moore, A. Z., Lemaitre, R. N., Jhun, M. A., Smith, J. A., Sotoodehnia, N., Bandinelli, S., Ferrucci, L., Arnett, D. K., Grallert, H., Assimes, T. L., Hou, L., Baccarelli, A., Whitsel, E. A., van Dijk, K. W., Amin, N., Uitterlinden, A. G., Sijbrands, E. J. G., Franco, O. H., Dehghan, A., Spector, T. D., Dupuis, J., Hivert, M-F., Rotter, J. I., Meigs, J. B., Pankow, J. S., van Meurs, J. B. J., Isaacs, A., Boomsma, D. I., Bell, J. T., Demirkan, A. & van Duijn, C. M., 13 Jun 2019, In : Nature Communications. 10, 1, p. 2581

Research output: Contribution to JournalArticleAcademicpeer-review

homeostasis
insulin
methylation
Methylation
DNA Methylation

A Potential Role for the STXBP5-AS1 Gene in Adult ADHD Symptoms

The EAGLE-ADHD Consortium, 18 Jan 2019, In : Behavior Genetics. p. 1-16 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Impulsive Behavior
Single Nucleotide Polymorphism
Meta-Analysis
signs and symptoms (animals and humans)
meta-analysis

Assessing Amyloid Pathology in Cognitively Normal Subjects Using 18 F-Flutemetamol PET: Comparing Visual Reads and Quantitative Methods

Collij, L. E., Konijnenberg, E., Reimand, J., Kate, M. T., Braber, A. D., Alves, I. L., Zwan, M., Yaqub, M., van Assema, D. M. E., Wink, A. M., Lammertsma, A. A., Scheltens, P., Visser, P. J., Barkhof, F. & van Berckel, B. N. M., May 2019, In : Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 60, 5, p. 541-547 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Amyloid
Pathology
Population
Coffee
ROC Curve

Association between rs1051730 and smoking during pregnancy in Dutch women

Mbarek, H., van Beijsterveldt, C. E. M., Hottenga, J. J., Dolan, C. V., Boomsma, D. I., Willemsen, G. & Vink, J. M., Jun 2019, In : Nicotine and Tobacco Research. 21, 6, p. 835-840 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Smoking
Pregnancy
Pregnant Women
Parturition
Smoking Cessation

Association of amyloid pathology with memory performance and cognitive complaints in cognitively normal older adults: a monozygotic twin study

Konijnenberg, E., den Braber, A., ten Kate, M., Tomassen, J., Mulder, S. D., Yaqub, M., Teunissen, C. E., Lammertsma, A. A., van Berckel, B. N. M., Scheltens, P., Boomsma, D. I. & Visser, P. J., May 2019, In : Neurobiology of Aging. 77, p. 58-65 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Twin Studies
Monozygotic Twins
Amyloid
Pathology
Cerebrospinal Fluid

Association of Whole-Genome and NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M. G., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. JC., W J H Penninx, B. & Jansen, R., Jan 2019, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Major Depressive Disorder
Anisotropy
Genome
Beta Particles
Diffusion Tensor Imaging

Associations between Loneliness and Personality are Mostly Driven by a Genetic Association with Neuroticism

Abdellaoui, A., Chen, H-Y., Willemsen, G., Ehli, E. A., Davies, G. E., Verweij, K. J. H., Nivard, M. G., de Geus, E. J. C., Boomsma, D. I. & Cacioppo, J. T., Apr 2019, In : Journal of Personality. 87, 2, p. 386-397 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Loneliness
Personality
Monozygotic Twins
Neuroticism
Molecular Biology

A twin study on the correlates of voluntary exercise behavior in adolescence

Schutte, N. M., Nederend, I., Bartels, M. & de Geus, E. J. C., 1 Jan 2019, In : Psychology of Sport and Exercise. 40, p. 99-109 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Twin Studies
Exercise
Aptitude
Individuality
Personality

Awareness and perceptions of clinical guidelines for the diagnostics and treatment of severe behavioural problems in children across Europe: A qualitative survey with academic experts

Gatej, A-R., Lamers, A., van Domburgh, L., Crone, M., Ogden, T., Rijo, D., Aronen, E., Barroso, R., Boomsma, D. I. & Vermeiren, R., Apr 2019, In : European Psychiatry. 57, p. 1-9 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Guidelines
Practice Guidelines
Therapeutics
Textbooks
Evidence-Based Practice

Biological insights into multiple birth: genetic findings from UK Biobank

Mbarek, H., van de Weijer, M. P., van der Zee, M. D., Ip, H. F., Beck, J. J., Abdellaoui, A., Ehli, E. A., Davies, G. E., Baselmans, B. M. L., Nivard, M. G., Bartels, M., de Geus, E. J. & Boomsma, D. I., Jun 2019, In : European Journal of Human Genetics. 27, 6, p. 970-979 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Multiple Birth Offspring
Fertility
Dizygotic Twins
Genome-Wide Association Study
Mothers
Social Class
Netherlands
Individuality
Problem Behavior
United Kingdom

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Davies, G. E., Ehli, E. A., Fedko, I. O., Groen-Blokhuis, M. M., Hammerschlag, A. R., Hottenga, J. J., Hudziak, J. & Ouwens, K. G., Jan 2019, In : Nature Genetics. 51, 1, p. 63-75 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Attention Deficit Disorder with Hyperactivity
Genome
Genome-Wide Association Study
Meta-Analysis
Population

EEG-based age-prediction models as stable and heritable indicators of brain maturational level in children and adolescents

Vandenbosch, M. M. L. J. Z., Ent, D. V. ., Boomsma, D. I., Anokhin, A. P. & Smit, D. J. A., 15 Apr 2019, In : Human Brain Mapping. 40, 6, p. 1919-1926 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Electroencephalography
Brain
Puberty
Netherlands
Longitudinal Studies

Een tweelingstudie naar indicatoren van genetische en culturele transmissie

van der Laan, C. M., vande Weijer, S. G. A., Nivard, M. G. & Boomsma, D. I., Apr 2019, In : Tijdschrift voor Criminologie. 2019, 2, p. 148-164 17 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Effects of early social deprivation on epigenetic statuses and adaptive behavior of young children: A study based on a cohort of institutionalized infants and toddlers

Naumova, O. Y., Rychkov, S. Y., Kornilov, S. A., Odintsova, V. V., Anikina, V. O., Solodunova, M. Y., Arintcina, I. A., Zhukova, M. A., Ovchinnikova, I. V., Burenkova, O. V., Zhukova, O. V., Muhamedrahimov, R. J. & Grigorenko, E. L., 26 Mar 2019, In : PLoS ONE. 14, 3, p. 1-29 29 p., e0214285.

Research output: Contribution to JournalArticleAcademicpeer-review

toddlers
Psychological Adaptation
Epigenomics
epigenetics
DNA Methylation

Eleven loci with new reproducible genetic associations with allergic disease risk

23Andme Research Team, Feb 2019, In : Journal of Allergy and Clinical Immunology. 143, 2, p. 691-699 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-Wide Association Study
Genes
Interleukin-27
Seasonal Allergic Rhinitis
Eczema

Enhanced GABAergic Immunoreactivity in Hippocampal Neurons and Astroglia of Multiple Sclerosis Patients

Kiljan, S., Prins, M., Baselmans, B. M., Bol, J. G. J. M., Schenk, G. J. & van Dam, A. M., 1 Jun 2019, In : Journal of neuropathology and experimental neurology. 78, 6, p. 480-491 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Glutamate Decarboxylase
Astrocytes
Multiple Sclerosis
Neurons
Acids

Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults

BIOS Consortium & Rodrigues Zilhao Nogueira, N., 1 Mar 2019, In : Biological Psychiatry.

Research output: Contribution to JournalArticleAcademicpeer-review

Attention Deficit Disorder with Hyperactivity
Methylation
DNA Methylation
Netherlands
Meta-Analysis

Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci

Gupta, R., Van Dongen, J., Fu, Y., Abdellaoui, A., Tyndale, R. F., Velagapudi, V., Boomsma, D. I., Korhonen, T., Kaprio, J., Loukola, A. & Ollikainen, M., 5 Jan 2019, In : Clinical epigenetics. 11, 1, p. 1-13 13 p., 1.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Cotinine
Nicotine
DNA Methylation
Smoking
Serum

Estimating the risk of PTSD in recent trauma survivors: results of the International Consortium to Predict PTSD (ICPP)

International Consortium to Predict PTSD, Feb 2019, In : World Psychiatry. 18, 1, p. 77-87 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Post-Traumatic Stress Disorders
Survivors
Wounds and Injuries
Diagnostic and Statistical Manual of Mental Disorders
Education

Evidence of causal effect of major depression on alcohol dependence: Findings from the psychiatric genomics consortium

Polimanti, R., Peterson, R. E., Ong, J. S., MacGregor, S., Edwards, A. C., Clarke, T. K., Frank, J., Gerring, Z., Gillespie, N. A., Lind, P. A., Maes, H. H., Martin, N. G., Mbarek, H., Medland, S. E., Streit, F., Agrawal, A., Edenberg, H. J., Kendler, K. S., Lewis, C. M., Sullivan, P. F. & 3 othersWray, N. R., Gelernter, J. & Derks, E. M., May 2019, In : Psychological Medicine. 49, 7, p. 1218-1226 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genomics
Alcoholism
Psychiatry
Alcohol Drinking
Depression

Genetic Influences on the Development of Cerebral Cortical Thickness During Childhood and Adolescence in a Dutch Longitudinal Twin Sample: The Brainscale Study

Teeuw, J., Brouwer, R. M., Koenis, M. M. G., Swagerman, S. C., Boomsma, D. I. & Hulshoff Pol, H. E., Mar 2019, In : Cerebral Cortex. 29, 3, p. 978-993 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Psychiatry
Magnetic Resonance Imaging
Brain

Genetic Vulnerability for Smoking and Cannabis Use: Associations With E-Cigarette and Water Pipe Use

International Cannabis Consortium, 21 May 2019, In : Nicotine and Tobacco Research. 21, 6, p. 723-730 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Marijuana Smoking
Smoking
Water
Cannabis
Phenotype

Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways

The 23andMe Research Team, Mar 2019, In : Nature Genetics. 51, 3, p. 394-403 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Sleep Initiation and Maintenance Disorders
Genome
Sleep
Genes
Neurons

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Social Science Genetic Association Consortium, 23and Me Research Team, eQTLGen Consortium & International Cannabis Consortium, 1 Feb 2019, In : Nature Genetics. 51, 2, p. 245-257 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic Loci
Genome-Wide Association Study
Single Nucleotide Polymorphism
Computational Biology
Synaptic Transmission

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

van Setten, J., Verweij, N., Mbarek, H., Niemeijer, M. N., Trompet, S., Arking, D. E., Brody, J. A., Gandin, I., Grarup, N., Hall, L. M., Hemerich, D., Lyytikäinen, L. P., Mei, H., Müller-Nurasyid, M., Prins, B. P., Robino, A., Smith, A. V., Warren, H. R., Asselbergs, F. W., Boomsma, D. I. & 41 othersCaulfield, M. J., Eijgelsheim, M., Ford, I., Hansen, T., Harris, T. B., Heckbert, S. R., Hottenga, J. J., Iorio, A., Kors, J. A., Linneberg, A., MacFarlane, P. W., Meitinger, T., Nelson, C. P., Raitakari, O. T., Silva Aldana, C. T., Sinagra, G., Sinner, M., Soliman, E. Z., Stoll, M., Uitterlinden, A., van Duijn, C. M., Waldenberger, M., Alonso, A., Gasparini, P., Gudnason, V., Jamshidi, Y., Kääb, S., Kanters, J. K., Lehtimäki, T., Munroe, P. B., Peters, A., Samani, N. J., Sotoodehnia, N., Ulivi, S., Wilson, J. G., de Geus, E. J. C., Jukema, J. W., Stricker, B., van der Harst, P., de Bakker, P. I. W. & Isaacs, A., Jun 2019, In : European Journal of Human Genetics. 27, 6, p. 952-962 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Quantitative Trait Loci
Genome-Wide Association Study
Single Nucleotide Polymorphism
Meta-Analysis
Genome

Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts

Zhang, X., Abdellaoui, A., Rucker, J., de Jong, S., Potash, J. B., Weissman, M. M., Shi, J., Knowles, J. A., Pato, C., Pato, M., Sobell, J., Smit, J. H., Hottenga, J. J., de Geus, E. J. C., Lewis, C. M., Buttenschøn, H. N., Craddock, N., Jones, I., Jones, L., McGuffin, P. & 13 othersMors, O., Owen, M. J., Preisig, M., Rietschel, M., Rice, J. P., Rivera, M., Uher, R., Gejman, P. V., Sanders, A. R., Boomsma, D., Penninx, B. W. J. H., Breen, G. & Levinson, D. F., 15 Jun 2019, In : Biological Psychiatry. 85, 12, p. 1065-1073 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Major Depressive Disorder
Genome
Intergenic DNA
Nucleic Acid Regulatory Sequences
Genome-Wide Association Study

Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

eQTLGen Consortium, 15 Jan 2019, In : eLife. 8, p. 1-40 40 p., e39856.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Genomics
Genes
Furin
Transport Vesicles
Peer Review

Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits

Grotzinger, A. D., Rhemtulla, M., de Vlaming, R., Ritchie, S. J., Mallard, T. T., Hill, W. D., Ip, H. F., Marioni, R. E., McIntosh, A. M., Deary, I. J., Koellinger, P. D., Harden, K. P., Nivard, M. G. & Tucker-Drob, E. M., 1 Mar 2019, In : Nature Human Behaviour.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-Wide Association Study
Single Nucleotide Polymorphism
Phenotype
Genetic Models
Psychiatry

Homogenizing estimates of heritability among SOLAR-eclipse, OpenMX, APACE, and FPHI software packages in neuroimaging data

Kochunov, P., Patel, B., Ganjgahi, H., Donohue, B., Ryan, M., Hong, E. L., Chen, X., Adhikari, B., Jahanshad, N., Thompson, P. M., Van’t Ent, D., den Braber, A., de Geus, E. J. C., Brouwer, R. M., Boomsma, D. I., Hulshoff Pol, H. E., de Zubicaray, G. I., McMahon, K. L., Martin, N. G., Wright, M. J. & 1 othersNichols, T. E., Mar 2019, In : Frontiers in Neuroinformatics. 13, March, p. 1-11 11 p., 16.

Research output: Contribution to JournalArticleAcademicpeer-review

Diffusion tensor imaging
Neuroimaging
Maximum likelihood estimation
Software packages
Software

Identification of common genetic risk variants for autism spectrum disorder

Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, BUPGEN, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23Andme Research Team, Mar 2019, In : Nature Genetics. 51, 3, p. 431-444 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-Wide Association Study
Phenotype
Sample Size
Meta-Analysis
Autism Spectrum Disorder

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M. G., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., Jansen, R., Milaneschi, Y., Peyrot, W. J., Smit, J. H., W J H Penninx, B. & Posthuma, D., 11 Jun 2019, In : Nature Communications. 10, 1, p. 2548

Research output: Contribution to JournalArticleAcademicpeer-review

methylation
DNA Methylation
Fetal Blood
blood
Blood

Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine

BBMRI Metabolomics Consortium, 16 Apr 2019, In : Neurology. 92, 16, p. e1899-e1911 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Metabolome
HDL Lipoproteins
Migraine Disorders
Metabolomics
Omega-3 Fatty Acids

Low prevalence of male microchimerism in women with Mayer-Rokitansky-Küster-Hauser syndrome

Peters, H. E., Johnson, B. N., Ehli, E. A., Micha, D., Verhoeven, M. O., Davies, G. E., Dekker, J. J. M. L., Overbeek, A., Berg, M. H. V. D., Dulmen-den Broeder, E. V., Leeuwen, F. E. V., Mijatovic, V., Boomsma, D. I. & Lambalk, C. B., 21 May 2019, In : Human Reproduction.

Research output: Contribution to JournalArticleAcademicpeer-review

Chimerism
Anti-Mullerian Hormone
Freemartinism
Control Groups
Mullerian Ducts

Marriage as a training ground: Examining change in self-control and forgiveness over the first 4 years of marriage

Pronk, T. M., Buyukcan-Tetik, A., Iliás, M. M. A. H. & Finkenauer, C., 1 Jan 2019, In : Journal of Social and Personal Relationships. 36, 1, p. 109-130 22 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Forgiveness
self-control
Marriage
marriage
Aptitude

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

EGG Consortium, 1 May 2019, In : Nature Genetics. 51, 5, p. 804-814 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Birth Weight
Mothers
Blood Pressure
Alleles
Genome-Wide Association Study

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

Küpers, L. K., Monnereau, C., Sharp, G. C., Yousefi, P., Salas, L. A., Ghantous, A., Page, C. M., Reese, S. E., Wilcox, A. J., Czamara, D., Starling, A. P., Novoloaca, A., Lent, S., Roy, R., Hoyo, C., Breton, C. V., Allard, C., Just, A. C., Bakulski, K. M., Holloway, J. W. & 107 othersEverson, T. M., Xu, C. J., Huang, R. C., van der Plaat, D. A., Wielscher, M., Merid, S. K., Ullemar, V., Rezwan, F. I., Lahti, J., van Dongen, J., Langie, S. A. S., Richardson, T. G., Magnus, M. C., Nohr, E. A., Xu, Z., Duijts, L., Zhao, S., Zhang, W., Plusquin, M., DeMeo, D. L., Solomon, O., Heimovaara, J. H., Jima, D. D., Gao, L., Bustamante, M., Perron, P., Wright, R. O., Hertz-Picciotto, I., Zhang, H., Karagas, M. R., Gehring, U., Marsit, C. J., Beilin, L. J., Vonk, J. M., Jarvelin, M. R., Bergström, A., Örtqvist, A. K., Ewart, S., Villa, P. M., Moore, S. E., Willemsen, G., Standaert, A. R. L., Håberg, S. E., Sørensen, T. I. A., Taylor, J. A., Räikkönen, K., Yang, I. V., Kechris, K., Nawrot, T. S., Silver, M. J., Gong, Y. Y., Richiardi, L., Kogevinas, M., Litonjua, A. A., Eskenazi, B., Huen, K., Mbarek, H., Maguire, R. L., Dwyer, T., Vrijheid, M., Bouchard, L., Baccarelli, A. A., Croen, L. A., Karmaus, W., Anderson, D., de Vries, M., Sebert, S., Kere, J., Karlsson, R., Arshad, S. H., Hämäläinen, E., Routledge, M. N., Boomsma, D. I., Feinberg, A. P., Newschaffer, C. J., Govarts, E., Moisse, M., Fallin, M. D., Melén, E., Prentice, A. M., Kajantie, E., Almqvist, C., Oken, E., Dabelea, D., Boezen, H. M., Melton, P. E., Wright, R. J., Koppelman, G. H., Trevisi, L., Hivert, M. F., Sunyer, J., Munthe-Kaas, M. C., Murphy, S. K., Corpeleijn, E., Wiemels, J., Holland, N., Herceg, Z., Binder, E. B., Davey Smith, G., Jaddoe, V. W. V., Lie, R. T., Nystad, W., London, S. J., Lawlor, D. A., Relton, C. L., Snieder, H. & Felix, J. F., 23 Apr 2019, In : Nature Communications. 10, p. 1-11 11 p., 1893.

Research output: Contribution to JournalArticleAcademicpeer-review

methylation
DNA Methylation
Meta-Analysis
Methylation
deoxyribonucleic acid

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

Understanding Society Scientific Group, EPIC-CVD, GSCAN, Consortium for Genetics of Smoking Behaviour, CHD Exome+ consortium, 7 Jan 2019, In : Molecular Psychiatry. p. 1-18 18 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic Loci
Meta-Analysis
Smoking
Nucleotides
Exome

Multivariate genome-wide analyses of the well-being spectrum

BIOS Consortium, Mar 2019, In : Nature Genetics. 51, 3, p. 445-451 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-Wide Association Study
Genome
Meta-Analysis
Interneurons
Computational Biology

Neighbourhood characteristics and prevalence and severity of depression: pooled analysis of eight Dutch cohort studies

Generaal, E., Hoogendijk, E. O., Stam, M., Henke, C. E., Rutters, F., Oosterman, M., Huisman, M., Kramer, S. E., Elders, P. J. M., Timmermans, E. J., Lakerveld, J., Koomen, E., Ten Have, M., de Graaf, R., Snijder, M. B., Stronks, K., Willemsen, G., Boomsma, D. I., Smit, J. H. & Penninx, B. W. J. H., 6 May 2019, In : The British journal of psychiatry : the journal of mental science. p. 1-8 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Cohort Studies
Depression
Odds Ratio
Urbanization
Social Security

Optical coherence tomography angiography in preclinical Alzheimer's disease

van de Kreeke, J. A., Nguyen, H-T., Konijnenberg, E., Tomassen, J., den Braber, A., Ten Kate, M., Yaqub, M., van Berckel, B., Lammertsma, A. A., Boomsma, D. I., Tan, S. H., Verbraak, F. & Visser, P. J., 22 May 2019, In : British Journal of Ophthalmology.

Research output: Contribution to JournalArticleAcademicpeer-review

Optical Coherence Tomography
Angiography
Alzheimer Disease
Amyloid
Monozygotic Twins
Family Conflict
Causality
Genetic Predisposition to Disease
Self-Control
Netherlands

Parental Education and Genetics of BMI from Infancy to Old Age: A Pooled Analysis of 29 Twin Cohorts

Silventoinen, K., Jelenkovic, A., Latvala, A., Yokoyama, Y., Sund, R., Sugawara, M., Tanaka, M., Matsumoto, S., Aaltonen, S., Piirtola, M., Freitas, D. L., Maia, J. A., Öncel, S. Y., Aliev, F., Ji, F., Ning, F., Pang, Z., Rebato, E., Saudino, K. J., Cutler, T. L. & 53 othersHopper, J. L., Ullemar, V., Almqvist, C., Magnusson, P. K. E., Cozen, W., Hwang, A. E., Mack, T. M., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Nelson, T. L., Whitfield, K. E., Sung, J., Kim, J., Lee, J., Lee, S., Llewellyn, C. H., Fisher, A., Medda, E., Nisticò, L., Toccaceli, V., Baker, L. A., Tuvblad, C., Corley, R. P., Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Knafo-Noam, A., Mankuta, D., Abramson, L., Burt, S. A., Klump, K. L., Silberg, J. L., Maes, H. H., Krueger, R. F., McGue, M., Pahlen, S., Gatz, M., Butler, D. A., Harris, J. R., Nilsen, T. S., Harden, K. P., Tucker-Drob, E. M., Franz, C. E., Kremen, W. S., Lyons, M. J., Lichtenstein, P., Jeong, H. U., Hur, Y. M., Boomsma, D. I., Sørensen, T. I. A. & Kaprio, J., 1 May 2019, In : Obesity. 27, 5, p. 855-865 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Education
Parents
Far East
Social Environment
Genetic Predisposition to Disease
Twin Studies
Apgar Score
Dizygotic Twins
Monozygotic Twins
Labor Presentation

Retinal layer thickness in preclinical Alzheimer's disease

van de Kreeke, J. A., Nguyen, H-T., den Haan, J., Konijnenberg, E., Tomassen, J., den Braber, A., Ten Kate, M., Collij, L., Yaqub, M., van Berckel, B., Lammertsma, A. A., Boomsma, D. I., Tan, H. S., Verbraak, F. D. & Visser, P. J., 6 May 2019, In : Acta Ophthalmologica.

Research output: Contribution to JournalArticleAcademicpeer-review

Alzheimer Disease
Nerve Fibers
Amyloid
Biomarkers
Monozygotic Twins

Skewed X-inactivation is common in the general female population

BIOS Consortium, Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J. & Willemsen, G., Mar 2019, In : European Journal of Human Genetics. 27, 3, p. 455-465 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

X Chromosome Inactivation
X Chromosome
Population
Genes
Alleles