Center for Neurogenomics and Cognitive Research

Research output

Research output per year 1986 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025

• 2134 Article
• 221 PhD-Thesis - Research and graduation internal
• 106 Review article
• 68 Chapter
• 165 More
  • 44 PhD-Thesis – Research external, graduation internal
  • 42 Comment / Letter to the editor
  • 21 Erratum / Corrigendum
  • 13 Meeting Abstract
  • 9 Editorial
  • 8 Conference contribution
  • 7 Inaugural speech
  • 5 Short survey
  • 4 Book
  • 4 Poster
  • 2 PhD-Thesis – Research internal, graduation external
  • 1 Entry for encyclopedia/dictionary
  • 1 Foreword/postscript
  • 1 Paper
  • 1 Letter
  • 1 Software
  • 1 Preprint

Research output per year

Research output per year

Search results

• 2025

  Metabolomics profiling of Type D personality traits

  Li-Gao, R., Bot, M., Willemsen, G., Penninx, B. W. J. H., de Geus, E. J. C., Boomsma, D. I., Kupper, N. & for the BBMRI-NL Metabolomics Consortium, Jan 2025, In: Journal of Psychosomatic Research. 188, 111994.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Very Low Density Lipoprotein 100%
  • Type D Behavior 100%
  • Total Fatty Acids 66%
  • Omega-3 Fatty Acid 60%
  • Triacylglycerol 60%
• 2024

  Border-ownership tuning determines the connectivity between V4 and V1 in the macaque visual system

  Jeurissen, D., van Ham, A. F., Gilhuis, A., Papale, P., Roelfsema, P. R. & Self, M. W., Dec 2024, In: Nature Communications. 15, 1, p. 1-17 17 p., 9115.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Visual Cortex 100%
  • Negative Feedback 100%

• Punishment-resistant alcohol intake is mediated by the nucleus accumbens shell in female rats

  McDonald, A. J., Nemat, P., van ‘t Hullenaar, T., Schetters, D., van Mourik, Y., Alonso-Lozares, I., De Vries, T. J. & Marchant, N. J., Dec 2024, In: Neuropsychopharmacology. 49, 13, p. 2022-2031 10 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Female Rats 100%
  • Nucleus Accumbens Shell 100%
  • Alcohol Abuse 75%
  • Behavior (Neuroscience) 50%
  • Neuronal Activity 25%

• Muscle type-specific effects of bilateral abobotulinumtoxinA injection on muscle growth and contractile function in spastic mice

  Rivares, C., Vignaud, A., Noort, W., Baan, G., Koopmans, B., Loos, M., Wüst, R. C. I., Kalinichev, M. & Jaspers, R. T., 30 Nov 2024, In: FASEB Journal. 38, 22, p. 1-26 26 p., e70141.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Glycine Receptor 100%

• V1 neurons are tuned to perceptual borders in natural scenes

  Papale, P., Zuiderbaan, W., Teeuwen, R. R. M., Gilhuis, A., Self, M. W., Roelfsema, P. R. & Dumoulin, S. O., 12 Nov 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 46, p. 1-10 10 p., e2221623121.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Driven Activity 100%
  • Primary Visual Cortex 100%
  • Visual Cortex 100%

• Stimulant medication and symptom interrelations in children, adolescents and adults with attention-deficit/hyperactivity disorder

  van der Pal, Z., Geurts, H. M., Haslbeck, J. M. B., van Keeken, A., Bruijn, A. M., Douw, L., van Rooij, D., Franke, B., Buitelaar, J., Lambregts-Rommelse, N., Hartman, C., Oosterlaan, J., Luman, M., Reneman, L., Hoekstra, P. J., Blanken, T. F. & Schrantee, A., 11 Nov 2024, (E-pub ahead of print) In: European child & adolescent psychiatry.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Attention Deficit Disorder 100%
  • Analeptic 100%
  • Adolescence 100%
  • Attention Deficit Hyperactivity Disorder 100%
  • Treatment Response 9%

• Genetic Heterogeneity Across Dimensions of Alcohol Use Behaviors

  Savage, J. E., Barr, P. B., Phung, T., Lee, Y. H., Zhang, Y., McCutcheon, V. V., COGA Investigators, Ge, T., Smoller, J. W., Davis, L. K., Meyers, J., Porjesz, B., Posthuma, D., Mallard, T. T. & Sanchez-Roige, S., 7 Nov 2024, In: The American journal of psychiatry. 181, 11, p. 1006-1017

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  File

  • Genetic Heterogeneity 100%
  • Genome-Wide Association Study 100%
  • Genetic Determinism 25%
  • Genetic Correlation 25%
  • Genetic Structure 25%
  8 Downloads (Pure)

• Epigenetic signatures of asthma: a comprehensive study of DNA methylation and clinical markers

  Van Asselt, A. J., Beck, J. J., Finnicum, C. T., Johnson, B. N., Kallsen, N., Viet, S., Huizenga, P., Ligthart, L., Hottenga, J. J., Pool, R., der Zee, A. H. M. V., Vijverberg, S. J., de Geus, E., Boomsma, D. I., Ehli, E. A. & van Dongen, J., 2 Nov 2024, In: Clinical epigenetics. 16, 1, 151.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Epigenetics 100%
  • Epigenome 100%
  • DNA Methylation 100%
  • Asthma 100%
  • Single Nucleotide Polymorphism 50%

• Associations between white matter microstructure and cognitive decline in major depressive disorder versus controls in Germany: a prospective case-control cohort study

  FOR2107 consortium, Nov 2024, In: The Lancet Psychiatry. 11, 11, p. 899-909 11 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Major Depressive Disorder 100%
  • Cognitive Disorders 36%
  • Diffusion MRI 27%
  • Depression 18%
  • Mood Disorder 9%

• Evaluation of 100 Dutch cases with 16p11.2 deletion and duplication syndromes; from clinical manifestations towards personalized treatment options

  Vos, N., Kleinendorst, L., van der Laan, L., van Uhm, J., Jansen, P. R., van Eeghen, A. M., Maas, S. M., Mannens, M. M. A. M. & van Haelst, M. M., Nov 2024, In: European Journal of Human Genetics. 32, 11, p. 1387-1401 15 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Microcephaly 100%
  • Body Mass Index 100%
  • Polyphagia 100%
  • Mental Retardation 100%
  • Awareness 100%

• Evaluation of the psychometric properties of the UBACC questionnaire in a multi-country psychiatric study in Africa

  Kipkemoi, P., Mufford, M. S., Akena, D., Alemayehu, M., Atwoli, L., Chibnik, L. B., Gelaye, B., Gichuru, S., Kariuki, S. M., Koenen, K. C., Kwobah, E., Kyebuzibwa, J., Mwema, R. M., Newton, C. R. J. C., Pretorius, A., Stein, D. J., Stevenson, A., Stroud, R. E., Teferra, S., Zingela, Z., & 2 othersPost, K. & Korte, K. J., Nov 2024, In: Comprehensive Psychiatry. 135, p. 1-9 9 p., 152526.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Exploratory Factor Analysis 100%
  • Three-Factor Model 100%
  • Factor Analysis 100%

• Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries

  García-Marín, L. M., Campos, A. I., Diaz-Torres, S., Rabinowitz, J. A., Ceja, Z., Mitchell, B. L., Grasby, K. L., Thorp, J. G., Agartz, I., Alhusaini, S., Ames, D., Amouyel, P., Andreassen, O. A., Arfanakis, K., Arias-Vasquez, A., Armstrong, N. J., Athanasiu, L., Bastin, M. E., Beiser, A. S., Bennett, D. A., & 170 othersBis, J. C., Boks, M. P. M., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Buitelaar, J. K., Burkhardt, R., Cahn, W., Calhoun, V. D., Carmichael, O. T., Chakravarty, M., Chen, Q., Ching, C. R. K., Cichon, S., Crespo-Facorro, B., Crivello, F., Dale, A. M., Smith, G. D., de Geus, E. J. C., De Jager, P. L., de Zubicaray, G. I., Debette, S., DeCarli, C., Depondt, C., Desrivières, S., Djurovic, S., Ehrlich, S., Erk, S., Espeseth, T., Fernández, G., Filippi, I., Fisher, S. E., Fleischman, D. A., Fletcher, E., Fornage, M., Forstner, A. J., Francks, C., Franke, B., Ge, T., Goldman, A. L., Grabe, H. J., Green, R. C., Grimm, O., Groenewold, N. A., Gruber, O., Gudnason, V., Håberg, A. K., Haukvik, U. K., Heinz, A., Hibar, D. P., Hilal, S., Himali, J. J., Ho, B. C., Hoehn, D. F., Hoekstra, P. J., Hofer, E., Hoffmann, W., Holmes, A. J., Homuth, G., Hosten, N., Ikram, M. K., Ipser, J. C., Jack, C. R., Jahanshad, N., Jönsson, E. G., Kahn, R. S., Kanai, R., Klein, M., Knol, M. J., Launer, L. J., Lawrie, S. M., Hellard, S. L., Lee, P. H., Lemaître, H., Li, S., Liewald, D. C. M., Lin, H., Longstreth, W. T., Lopez, O. L., Luciano, M., Maillard, P., Marquand, A. F., Martin, N. G., Martinot, J. L., Mather, K. A., Mattay, V. S., McMahon, K. L., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mirza-Schreiber, N., Milaneschi, Y., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Maniega, S. M., Nauck, M., Nho, K., Niessen, W. J., Nöthen, M. M., Nyquist, P. A., Oosterlaan, J., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Psaty, B. M., Pütz, B., Reppermund, S., Rietschel, M. D., Risacher, S. L., Romanczuk-Seiferth, N., Romero-Garcia, R., Roshchupkin, G. V., Rotter, J. I., Sachdev, P. S., Sämann, P. G., Saremi, A., Sargurupremraj, M., Saykin, A. J., Schmaal, L., Schmidt, H., Schmidt, R., Schofield, P. R., Scholz, M., Schumann, G., Schwarz, E., Shen, L., Shin, J., Sisodiya, S. M., Smith, A. V., Smoller, J. W., Soininen, H. S., Steen, V. M., Stein, D. J., Stein, J. L., Thomopoulos, S. I., Toga, A. W., Tordesillas-Gutiérrez, D., Trollor, J. N., Valdes-Hernandez, M. C., van ′t Ent, D., van Bokhoven, H., van der Meer, D., van der Wee, N. J. A., Vázquez-Bourgon, J., Veltman, D. J., Vernooij, M. W., Villringer, A., Vinke, L. N., Völzke, H., Walter, H., Wardlaw, J. M., Weinberger, D. R., Weiner, M. W., Wen, W., Westlye, L. T., Westman, E., White, T., Witte, A. V., Wolf, C., Yang, J., Zwiers, M. P., Ikram, M. A., Seshadri, S., Thompson, P. M., Satizabal, C. L., Medland, S. E. & Rentería, M. E., Nov 2024, In: Nature genetics. 56, 11, p. 2333-2344 12 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Parkinson's Disease 100%
  • Caudate Nucleus 100%
  • Intracellular Signaling 100%
  • Brainstem 100%
  • Attention Deficit Hyperactivity Disorder 100%

• Hyperarousal dynamics reveal an overnight increase boosted by insomnia

  Rösler, L., van Kesteren, E. J., Leerssen, J., van der Lande, G., Lakbila-Kamal, O., Foster-Dingley, J. C., Albers, A. & van Someren, E. JW., Nov 2024, In: Journal of Psychiatric Research. 179, p. 279-285 7 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Fight-or-Flight Response 100%
  • Sleep Quality 36%
  • Personality Traits 9%
  • Cortisol 9%
  • Stress-Related Disorders 9%

• Leukoencephalopathy with calcifications, developmental brain abnormalities and skeletal dysplasia due to homozygosity for a hypomorphic CSF1R variant: A report of three siblings

  Beerepoot, S., Verbeke, J. I. M. L., Plantinga, M., Nierkens, S., Pouwels, P. J. W., Wolf, N. I., Simons, C. & van der Knaap, M. S., Nov 2024, In: American Journal of Medical Genetics, Part A. 194, 11, p. 1-9 9 p., e63800.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Skeletal Survey 100%
  • Osteosclerosis 100%

• The association of overweight, obesity, and long-term obesity with SARS-CoV-2 infection: a meta-analysis of 9 population-based cohorts from the Netherlands Cohorts Consortium

  Loef, B., Boer, J. M. A., Beekman, M., Huider, F., Boomsma, D. I., van Dongen, J., de Geus, E. J. C., Huisman, M., Stronks, K., Verschuren, W. M. M., van den Berg, S. W. & Lifelines Corona Research initiative, 31 Oct 2024, (Accepted/In press) In: International Journal of Obesity.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Meta-Analysis 100%
  • Confidence Interval 100%
  • Odds Ratio 100%
  • Meta Analysis 100%
  • Severe Acute Respiratory Syndrome 100%

• Involvement of a lateral entorhinal cortex engram in episodic-like memory recall

  Tozzi, F., Guglielmo, S., Paraciani, C., van den Oever, M. C., Mainardi, M., Cattaneo, A. & Origlia, N., 22 Oct 2024, In: Cell Reports. 43, 10, p. 1-17 18 p., 114795.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Episodic-Like Memory 100%

• Activity dependent modulation of glial gap junction coupling in the thalamus

  Baum, P., Beinhauer, A., Zirwes, L., Loenneker, L., Jabs, R., Narayanan, R. T., Oberlaender, M., Seifert, G., Kettenmann, H. & Steinhäuser, C., 18 Oct 2024, In: iScience. 27, 10, p. 1-15 16 p., 111043.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Neuronal Activity 100%
  • Thalamus 100%
  • Gap Junction 100%
  • In Vivo 50%
  • Gap Junction Protein 50%

• Development of a Diabetes Dietary Quality Index: Reproducibility and Associations with Measures of Insulin Resistance, Beta Cell Function, and Hyperglycemia

  Zelis, M., Simonis, A. M. C., van Dam, R. M., Boomsma, D. I., van Lee, L., Kramer, M. H. H., Serné, E. H., van Raalte, D. H., Mari, A., de Geus, E. J. C. & Eekhoff, E. M. W., 16 Oct 2024, In: Nutrients. 16, 20, 3512.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Reproducibility 100%
  • Insulin Resistance 100%
  • Hyperglycemia 100%
  • Diabetes 100%
  • Beta Cell 100%

• Dominant CST3 variants cause adult onset leukodystrophy without amyloid angiopathy

  Bergner, C. G., Breur, M., Soto-Bernardini, M. C., Schäfer, L., Lier, J., Le Duc, D., Bundalian, L., Schubert, S., Brenner, D., Kreuz, F. R., Schulte, B., Waisfisz, Q., Bugiani, M., Köhler, W., Sticht, H., Abou Jamra, R. & van der Knaap, M. S., 3 Oct 2024, In: Brain : a journal of neurology. 147, 10, p. 3562-3572 11 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Leukodystrophy 100%
  • Vascular Amyloidosis 100%
  • Amyloid Protein 100%
  • Vascular Disease 100%
  • Diseases 25%

• Genetic Influence on Social Support: A Twin Study

  Gonggrijp, B. M. A., van de Weijer, S. G. A., van Dongen, J., Bijleveld, C. C. J. H. & Boomsma, D. I., 2 Oct 2024, (E-pub ahead of print) In: Twin research and human genetics : the official journal of the International Society for Twin Studies. p. 1-5 5 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Genetic Influence 100%
  • Social Support 100%
  • Heritability 50%
  • Social Support Questionnaire 16%

• Case report: Spontaneous improvement and treatment considerations in leukoencephalopathy with calcifications and cysts

  Beerepoot, S., Ardon, H., Niers, A. & van der Knaap, M. S., Oct 2024, In: Clinical Neurology and Neurosurgery. 245, p. 1-4 4 p., 108517.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Leukoencephalopathy 100%
  • Bevacizumab 100%
  • Diseases 25%
  • Combination Therapy 25%
  • Disease Course 25%

• Exome sequencing of 20,979 individuals with epilepsy reveals shared and distinct ultra-rare genetic risk across disorder subtypes

  Epi25 Collaborative, Oct 2024, In: Nature neuroscience. 27, 10, p. 1864-1879 16 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Epilepsy Subtypes 100%
  • Ion Channel 33%

• Heterozygous missense CSF1R variants hamper in vitro CD34+-derived dendritic cell generation but not in vivo dendritic cell development

  Beerepoot, S., Wolf, N. I., van der Knaap, M. S., Nierkens, S. & Plantinga, M., Oct 2024, In: Molecular Immunology. 174, p. 41-46 6 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Dendritic Cell 100%
  • CD34 100%
  • Cell Maturation 100%
  • Colony Stimulating Factor 1 Receptor 100%
  • Stem Cell 23%

• Maternal Characteristics in Natural and Medically Assisted Reproduction Dizygotic Twin Pregnancies

  Hubers, N., Page, C. M., Ligthart, L., Pool, R., Hottenga, J. J., van Dongen, J., Lambalk, C. B., Harris, J. R., Willemsen, G. & Boomsma, D. I., Oct 2024, In: Twin Research and Human Genetics. 27, 3, p. 135-141 7 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Child 100%
  • Maternal Age 100%
  • Twin Pregnancy 100%
  • In Vitro Fertilisation 100%
  • Dizygotic Twins 100%

• Refining the scope of genetic influences on alcohol misuse through environmental stratification and gene–environment interaction

  Spit for Science Working Group, Oct 2024, In: Alcohol, Clinical and Experimental Research. 48, 10, p. 1853-1865 13 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • DLGAP1 100%
  • Medical Aspects of Alcohol Misuse 100%
  • Socioeconomic Status 66%
  • Genetic Determinism 50%
  • Genetic Divergence 50%

• Pronouns reactivate conceptual representations in human hippocampal neurons

  Dijksterhuis, D. E., Self, M. W., Possel, J. K., Peters, J. C., van Straaten, E. C. W., Idema, S., Baaijen, J. C., van der Salm, S. M. A., Aarnoutse, E. J., van Klink, N. C. E., van Eijsden, P., Hanslmayr, S., Chelvarajah, R., Roux, F., Kolibius, L. D., Sawlani, V., Rollings, D. T., Dehaene, S. & Roelfsema, P. R., 27 Sept 2024, In: Science (New York, N.Y.). 385, 6716, p. 1478-1484 7 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Discourse Comprehension 100%
  • Dynamic Semantics 100%

• Framework for Multistakeholder Patient Registries in the Field of Rare Diseases: Focus on Neurogenetic Diseases

  Schoenmakers, D. H., Van Den Berg, S., Timmers, L., Adang, L. A., Bäumer, T., Bosch, A., Van De Casteele, M., Datema, M. R., Dekker, H., Donnelly, C., Driessens, M. H. E., Graessner, H., Greger, V., Haddad, T., Höglinger, G. U., Van Den Hout, H., Jonker, C., Langeveld, M., Lambert, L. J., Neacy, E., & 12 othersNieuwland, M., Klockgether, T., Van Der Knaap, M. S., Papadopoulou, A., Plueschke, K., Van Rijn, S., Rosenberg, N., Saunier-Vivar, E. F., Dos Santos Vieira, B., Hollak, C. E. M., Goettsch, W. G. & Wolf, N. I., 24 Sept 2024, In: Neurology. 103, 6, p. 1-12 12 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Diseases 100%
  • Rare Disease 100%
  • Patient Registry 100%
  • Technology Assessment 75%
  • Decision Making 25%

• Comparison of cell-free and small extracellular-vesicle-associated DNA by sequencing plasma of lung cancer patients

  Moldovan, N., Verkuijlen, S., van der Pol, Y., Bosch, L., van Weering, J. R. T., Bahce, I., Pegtel, D. M. & Mouliere, F., 20 Sept 2024, In: iScience. 27, 9, p. 1-11 12 p., 110742.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Mitochondrial DNA 100%

• The direct and indirect pathways of the basal ganglia antagonistically influence cortical activity and perceptual decisions

  van Beest, E. H., Abdelwahab, M. A. O., Cazemier, J. L., Baltira, C., Maes, M. C., Peri, B. D., Self, M. W., Willuhn, I. & Roelfsema, P. R., 20 Sept 2024, In: iScience. 27, 9, p. 1-21 22 p., 110753.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Basal Ganglia 100%
  • Working Memory 100%
  • Striatum 33%

• Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles

  Huffman, J. E., Nicholas, J., Hahn, J., Hottenga, J. J., de Geus, E., Willemsen, G., Boomsma, D., Sabater-Lleal, M., Morrison, A. C., Smith, N. L., VA Million Veteran Program & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, 5 Sept 2024, (Accepted/In press) In: Blood. 144, 21, p. 2248-2265

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Fibrinogen Blood Level 100%
  • Fibrinogen 100%
  • Whole Genome Sequencing 75%
  • Genotyping 50%
  • Minor Allele Frequency 25%

• Accelerated Cortical Thinning in Schizophrenia Is Associated With Rare and Common Predisposing Variation to Schizophrenia and Neurodevelopmental Disorders

  CIBERSAM group, 1 Sept 2024, In: Biological psychiatry. 96, 5, p. 376-389 14 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  File

  • Dementia Praecox 100%
  • Gene Expression 20%
  • Brain Development 10%
  • Longitudinal Study 10%
  • Genetic Variation 10%
  3 Downloads (Pure)

• A Bivariate Twin Study of Lifetime cannabis Initiation and Lifetime Regular Tobacco Smoking Across Three Different Countries

  Zellers, S., van Dongen, J., Maes, H. H. M., Ollikainen, M., Fang, F., Vrieze, S., Kaprio, J. & Boomsma, D. I., Sept 2024, In: Behavior Genetics. 54, 5, p. 375-385 11 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Twins 100%
  • Cannabis 100%
  • Lifespan 100%
  • Smoking Initiation 100%
  • Prevalence 75%

• Age Trajectories of the Structural Connectome in Child and Adolescent Offspring of Individuals With Bipolar Disorder or Schizophrenia

  Poortman, S. R., Barendse, M. E. A., Setiaman, N., van den Heuvel, M. P., de Lange, S. C., Hillegers, M. H. J. & van Haren, N. E. M., Sept 2024, In: Biological psychiatry global open science. 4, 5, p. 1-12 12 p., 100336.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Dementia Praecox 100%
  • Bipolar Disorder 100%
  • Severe Mental Illness 66%
  • Brain Network 50%

• Dnmt3a1 regulates hippocampus-dependent memory via the downstream target Nrp1

  Kupke, J., Klimmt, J., Mudlaff, F., Schwab, M., Lutsik, P., Plass, C., Sticht, C. & Oliveira, A. M. M., Sept 2024, In: Neuropsychopharmacology. 49, 10, p. 1528-1539 12 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Hippocampus 100%
  • Neuropilin-1 100%
  • Neuropilin 1 100%
  • Epigenetics 50%
  • Long Term Memory 50%

• Genome-Wide Association Study of Obsessive-Compulsive Symptoms including 33,943 individuals from the general population

  Strom, N. I., Burton, C. L., Iyegbe, C., Silzer, T., Antonyan, L., Pool, R., Lemire, M., Crowley, J. J., Hottenga, J. J., Ivanov, V. Z., Larsson, H., Lichtenstein, P., Magnusson, P., Rück, C., Schachar, R., Wu, H. M., Cath, D., Crosbie, J., Mataix-Cols, D., Boomsma, D. I., & 4 othersMattheisen, M., Meier, S. M., Smit, D. J. A. & Arnold, P. D., Sept 2024, In: Molecular Psychiatry. 29, 9, p. 2714-2723 10 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Population 100%
  • Genome-Wide Association Study 100%
  • Obsessive-Compulsive Disorder 100%
  • Single-Nucleotide Polymorphism 50%
  • Genetic Correlation 50%

• Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts

  Adams, M. J., Thorp, J. G., Jermy, B. S., Nivard, M. G., Milaneschi, Y., Penninx, B. W. J. H., Boomsma, D. I., Lewis, C. M., McIntosh, A. M., Derks, E. M. & Estonian Biobank Research Team, Sept 2024, In: Psychological Medicine. 54, 12, p. 3459-3468 10 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Major Depressive Disorder 100%
  • Meta-Analysis 100%
  • Depression 100%
  • Hypersomnia 50%
  • Genetics of Depression 50%

• NMR metabolomics-guided DNA methylation mortality predictors

  Bizzarri, D., Reinders, M. J. T., van Dongen, J., Pool, R., Boomsma, D. I., Willemsen, A. H. M., Slagboom, P. E., van den Akker, E. B. & BBMRI Consortium, Sept 2024, In: Ebiomedicine. 107, 105279.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Metabolomics 100%
  • DNA Methylation 100%
  • Metabolic Pathway 20%
  • Epigenetics 20%
  • Population Research 20%

• Axonal endoplasmic reticulum tubules control local translation via P180/RRBP1-mediated ribosome interactions

  Koppers, M., Özkan, N., Nguyen, H. H., Jurriens, D., McCaughey, J., Nguyen, D. T. M., Li, C. H., Stucchi, R., Altelaar, M., MacGillavry, H. D., Kapitein, L. C., Hoogenraad, C. C. & Farías, G. G., 19 Aug 2024, In: Developmental Cell. 59, 16, p. 2053-2068.e9

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Endoplasmic reticulum 100%
  • Ribosome 100%
  • Hippocampal Neuronal Culture 50%
  • Amino Acid Activation 33%
  • Eicosanoid Receptor 16%

• Unraveling robust brain-behavior links of depressive complaints through granular network models for understanding heterogeneity

  IMAGEN Consortium, 15 Aug 2024, In: Journal of Affective Disorders. 359, p. 140-144 5 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Behavior (Neuroscience) 100%
  • Depression 100%
  • Adolescent Depression 100%
  • Cognitive Disorders 50%
  • Brain Network 50%

• In vivo selection in non-human primates identifies AAV capsids for on-target CSF delivery to spinal cord

  Hanlon, K. S., Cheng, M., Montoro Ferrer, R., Ryu, J. R., Lee, B., De La Cruz, D., Patel, N., Espinoza, P., Santoscoy, M. C., Gong, Y., Ng, C., Nguyen, D. M., Nammour, J., Clark, S. W., Heine, V. M., Sun, W., Kozarsky, K. & Maguire, C. A., 7 Aug 2024, In: Molecular Therapy. 32, 8, p. 2584-2603 20 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • In Vivo 100%
  • Intrathecal 100%
  • Adeno-Associated Virus 100%
  • Transgene 100%
  • Adeno Associated Virus 100%

• Phenotype prediction using biologically interpretable neural networks on multi-cohort multi-omics data

  van Hilten, A., van Rooij, J., van Meurs, J. B. J., Roshchupkin, G. V., BIOS Consortium, Boomsma, D., Pool, R., van Dongen, J. & Hottenga, J. J., 2 Aug 2024, In: NPJ systems biology and applications. 10, 1, p. 81 1 p., 81.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Neural Network 100%
  • Multi-Omics 100%
  • COL11A2 100%
  • Methylation 25%
  • CD34 25%

• Comparison of electrical microstimulation artifact removal methods for high-channel-count prostheses

  Wang, F., Chen, X. & Roelfsema, P. R., Aug 2024, In: Journal of Neuroscience Methods. 408, p. 1-14 14 p., 110169.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Neuronal Activity 100%
  • DNA Template 100%
  • Visual Cortex 50%
  • Local Field Potential 50%
  • Stereotypic Movement Disorder 50%

• Prebiotic diet normalizes aberrant immune and behavioral phenotypes in a mouse model of autism spectrum disorder

  Prince, N., Peralta Marzal, L. N., Markidi, A., Ahmed, S., Adolfs, Y., Pasterkamp, R. J., Kumar, H., Roeselers, G., Garssen, J., Kraneveld, A. D. & Perez-Pardo, P., Aug 2024, In: ACTA PHARMACOLOGICA SINICA. 45, 8, p. 1591-1603 13 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Valproic Acid 100%
  • Pervasive Developmental Disorder 100%
  • Prebiotic Agent 100%
  • Galactose Oligosaccharide 60%
  • Fructose Oligosaccharide 60%

• Region-specific and age-related differences in astrocytes in the human brain

  Man, J. H. K., Breur, M., van Gelder, C. A. G. H., Marcon, G., Maderna, E., Giaccone, G., Altelaar, M., van der Knaap, M. S. & Bugiani, M., Aug 2024, In: Neurobiology of Aging. 140, p. 102-115 14 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Astrocyte 100%
  • Gray Matter 27%
  • Cell Density 18%
  • Proteomics 9%
  • Mass Spectrometry 9%

• Overlapping genetic influences between creativity and borderline personality symptoms in a large Dutch sample

  Azcona-Granada, N., Willemsen, G., Boomsma, D. I. & Sauce, B., 30 Jul 2024, In: Scientific Reports. 14, 1, p. 17589 17589.

  Research output: Contribution to Journal › Article › Academic › peer-review

  • Genetic Influence 100%
  • Borderline Personality Disorder 100%
  • Genetic Determinism 100%
  • Genetic Mechanism 50%
  • Heritability 12%

• Brain-age prediction: Systematic evaluation of site effects, and sample age range and size

  Yu, Y., Boomsma, D. I., Van't Ent, D., Frangou, S., Ge, R. & ENIGMA Lifespan Working Group, 15 Jul 2024, In: Human Brain Mapping. 45, 10, e26768.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Neuroimaging 100%
  • Brain Age 100%
  • Open Science 50%
  • Brain Development 12%

• Reduced Protein Stability of 11 Pathogenic Missense STXBP1/MUNC18-1 Variants and Improved Disease Prediction

  André, T., van Berkel, A. A., Singh, G., Abualrous, E. T., Diwan, G. D., Schmenger, T., Braun, L., Malsam, J., Toonen, R. F., Freund, C., Russell, R. B., Verhage, M. & Söllner, T. H., 15 Jul 2024, In: Biological psychiatry. 96, 2, p. 125-136 12 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • STXBP1 100%
  • Missense 100%
  • Protein Stability 100%
  • Solubility 28%
  • Protein Aggregation 14%

• Biphasic Npas4 expression promotes inhibitory plasticity and suppression of fear memory consolidation in mice

  Brito, D. V. C., Kupke, J., Sokolov, R., Cambridge, S., Both, M., Bengtson, C. P., Rozov, A. & Oliveira, A. M. M., Jul 2024, In: Molecular Psychiatry. 29, 7, p. 1929-1940 12 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Memory Consolidation 100%
  • Maladaptive Behavior 33%
  • Fear Response 33%
  • Hippocampus 33%
  • Contextual Fear Conditioning 33%

• Longitudinal volumetric analysis of gray matter atrophy in metachromatic leukodystrophy

  Al-Saady, M. L., Galabova, H., Schoenmakers, D. H., Beerepoot, S., Lindemans, C., van Hasselt, P. M., van der Knaap, M. S., Wolf, N. I. & Pouwels, P. J. W., Jul 2024, In: Journal of Inherited Metabolic Disease. 47, 4, p. 792-804 13 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Gray Matter 100%
  • Metachromatic Leukodystrophy 100%
  • Thalamus 45%
  • Cerebrum 27%
  • Hematopoietic Stem Cell 18%

• Progressive demyelinating polyneuropathy after hematopoietic cell transplantation in metachromatic leukodystrophy: a case series

  Beerepoot, S., Boelens, J. J., Lindemans, C., de Witte, M. A., Nierkens, S., Vrancken, A. F. J. E., van der Knaap, M. S., Bugiani, M. & Wolf, N. I., Jul 2024, In: Journal of Neurology. 271, 7, p. 4028-4038 11 p.

  Research output: Contribution to Journal › Article › Academic › peer-review

  Open Access

  • Polyneuropathy 100%
  • Cell Transplantation 100%
  • Hematopoietic Stem Cell 100%
  • Metachromatic Leukodystrophy 100%
  • Immunomodulatory Drug 30%