Research Output 2004 2019

Filter
Article
2019

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis

Liu, J., Carnero-Montoro, E., van Dongen, J., Lent, S., Nedeljkovic, I., Ligthart, S., Tsai, P. C., Martin, T. C., Mandaviya, P. R., Jansen, R., Peters, M. J., Duijts, L., Jaddoe, V. W. V., Tiemeier, H., Felix, J. F., Willemsen, G., de Geus, E. J. C., Chu, A. Y., Levy, D., Hwang, S. J. & 37 othersBressler, J., Gondalia, R., Salfati, E. L., Herder, C., Hidalgo, B. A., Tanaka, T., Moore, A. Z., Lemaitre, R. N., Jhun, M. A., Smith, J. A., Sotoodehnia, N., Bandinelli, S., Ferrucci, L., Arnett, D. K., Grallert, H., Assimes, T. L., Hou, L., Baccarelli, A., Whitsel, E. A., van Dijk, K. W., Amin, N., Uitterlinden, A. G., Sijbrands, E. J. G., Franco, O. H., Dehghan, A., Spector, T. D., Dupuis, J., Hivert, M. F., Rotter, J. I., Meigs, J. B., Pankow, J. S., van Meurs, J. B. J., Isaacs, A., Boomsma, D. I., Bell, J. T., Demirkan, A. & van Duijn, C. M., 13 Jun 2019, In : Nature Communications. 10, p. 1-11 11 p., 2581.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
homeostasis
insulin
methylation
Methylation
DNA Methylation

A spectrum of routing strategies for brain networks

Avena-Koenigsberger, A., Yan, X., Kolchinsky, A., van den Heuvel, M. P., Hagmann, P. & Sporns, O., 8 Mar 2019, In : PLoS Computational Biology. 15, 3, p. 1-24 24 p., e1006833.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
routing
animal communication
brain
Brain
Routing

Association of Whole-Genome and NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M. G., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. JC., W J H Penninx, B., Jansen, R. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jan 2019, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Major Depressive Disorder
Anisotropy
Genome
Radiation
Diffusion Tensor Imaging

Attention-deficit/hyperactivity disorder and lifetime cannabis use: genetic overlap and causality

ADHD Group of the Psychiatric Genomics Consortium, International Cannabis Consortium, 4 Jan 2019, In : Molecular Psychiatry. p. 1-11 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Cannabis
Attention Deficit Disorder with Hyperactivity
Causality
Substance-Related Disorders
Genome-Wide Association Study

Biological Characteristics of Connection-Wise Resting-State Functional Connectivity Strength

Pijnenburg, R., Scholtens, L. H., Mantini, D., Vanduffel, W., Barrett, L. F. & van den Heuvel, M. P., 21 Jan 2019, In : Cerebral Cortex.

Research output: Contribution to JournalArticleAcademicpeer-review

Strychnine
Macaca
Magnetic Resonance Imaging
Brain
gamma-Aminobutyric Acid

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Derks, E. M., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M., Peyrot, W. J., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., W J H Penninx, B. & Sullivan, P., 11 Nov 2019, In : Molecular Psychiatry.

Research output: Contribution to JournalArticleAcademicpeer-review

Bipolar Disorder
Psychiatry
Schizophrenia
Depression
Major Depressive Disorder

Brain connectivity alterations in early psychosis: from clinical to neuroimaging staging

Griffa, A., Baumann, P. S., Klauser, P., Mullier, E., Cleusix, M., Jenni, R., van den Heuvel, M. P., Do, K. Q., Conus, P. & Hagmann, P., 4 Feb 2019, In : Translational Psychiatry. 9, 1, p. 1-10 10 p., 62.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Neuroimaging
Psychotic Disorders
Brain
Discriminant Analysis
Connectome

Cell Replacement Therapy Improves Pathological Hallmarks in a Mouse Model of Leukodystrophy Vanishing White Matter

Dooves, S., Leferink, P. S., Krabbenborg, S., Breeuwsma, N., Bots, S., Hillen, A. E. J., Jacobs, G., van der Knaap, M. S. & Heine, V. M., 5 Mar 2019, In : Stem cell reports. 12, 3, p. 441-450 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Leukoencephalopathies
Cell- and Tissue-Based Therapy
Neuroglia
Stem Cells
Stem cells

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M., Peyrot, W. J., Posthuma, D. & Willemsen, G., 5 Aug 2019, In : Biological Psychiatry. p. 1-12 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
HLA Antigens
Haplotypes
Alleles
Depression
Major Histocompatibility Complex

Common Polygenic Variations for Psychiatric Disorders and Cognition in Relation to Brain Morphology in the General Pediatric Population

Alemany, S., Jansen, P. R., Muetzel, R. L., Marques, N., El Marroun, H., Jaddoe, V. W. V., Polderman, T. J. C., Tiemeier, H., Posthuma, D. & White, T., 9 Jan 2019, (Accepted/In press) In : Journal of the American Academy of Child and Adolescent Psychiatry. p. 1-8 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Cognition Disorders
Attention Deficit Disorder with Hyperactivity
Psychiatry
Pediatrics
Intelligence

Connectome-Based Patterns of First-Episode Medication-Naïve Patients With Schizophrenia

Cui, L-B., Wei, Y., Xi, Y-B., Griffa, A., De Lange, S. C., Kahn, R. S., Yin, H. & Van den Heuvel, M. P., 24 Oct 2019, In : Schizophrenia Bulletin. 45, 6, p. 1291-1299 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Connectome
Schizophrenia
Organizations
Functional Neuroimaging
Brain

Cross-sectional and longitudinal assessment of the upper cervical spinal cord in motor neuron disease

van der Burgh, H. K., Westeneng, H. J., Meier, J. M., van Es, M. A., Veldink, J. H., Hendrikse, J., van den Heuvel, M. P. & van den Berg, L. H., 2019, In : NeuroImage: Clinical. 24, p. 1-12 12 p., 101984.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Motor Neuron Disease
Amyotrophic Lateral Sclerosis
Motor Neurons
Nerve Degeneration
Brain

Discordant attributes of structural and functional brain connectivity in a two-layer multiplex network

Lim, S., Radicchi, F., van den Heuvel, M. P. & Sporns, O., 27 Feb 2019, In : Scientific Reports. 9, 1, p. 1-13 13 p., 2885.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Connectome
Brain
Magnetic Resonance Imaging

Evolutionary expansion of connectivity between multimodal association areas in the human brain compared with chimpanzees

Ardesch, D. J., Scholtens, L. H., Li, L., Preuss, T. M., Rilling, J. K. & van den Heuvel, M. P., 2 Apr 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 14, p. 7101-7106 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Pan troglodytes
Brain
Connectome
Language
Diffusion Magnetic Resonance Imaging

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

iPSYCH-GEMS Schizophrenia Working Group, CommonMind Consortium & The Schizophrenia Working Group of the PsyUniversity of Copenhagenchiatric Genomics Consortium, 25 Mar 2019, In : Nature Genetics. 51, 4, p. 659–674 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Genome-Wide Association Study
Prefrontal Cortex
Schizophrenia
Tay-Sachs Disease
Gene Expression

Genetic mapping and evolutionary analysis of human-expanded cognitive networks

Wei, Y., de Lange, S. C., Scholtens, L. H., Watanabe, K., Ardesch, D. J., Jansen, P. R., Savage, J. E., Li, L., Preuss, T. M., Rilling, J. K., Posthuma, D. & van den Heuvel, M. P., 24 Oct 2019, In : Nature Communications. 10, 1, p. 4839

Research output: Contribution to JournalArticleAcademicpeer-review

Brain
Genes
genes
brain
Genetic Loci

Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways

The 23andMe Research Team, Mar 2019, In : Nature Genetics. 51, 3, p. 394-403 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Sleep Initiation and Maintenance Disorders
Genome
Sleep
Genes
Neurons

Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence

Smeland, O. B., Bahrami, S., Frei, O., Shadrin, A., O’Connell, K., Savage, J., Watanabe, K., Krull, F., Bettella, F., Steen, N. E., Ueland, T., Posthuma, D., Djurovic, S., Dale, A. M. & Andreassen, O. A., 4 Jan 2019, In : Molecular Psychiatry. p. 1-10 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Intelligence
Bipolar Disorder
Schizophrenia
Genome
Alleles

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Social Science Genetic Association Consortium, 23and Me Research Team, eQTLGen Consortium & International Cannabis Consortium, 1 Feb 2019, In : Nature Genetics. 51, 2, p. 245-257 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Genetic Loci
Genome-Wide Association Study
Single Nucleotide Polymorphism
Computational Biology
Synaptic Transmission

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLGen Consortium, BIOS Consortium & the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, 1 May 2019, In : Nature Genetics. 51, 5, p. 793-803 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Genome-Wide Association Study
Bipolar Disorder
Genome
Neurotransmitter Transport Proteins
Endocannabinoids

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk

Jansen, I. E., Savage, J. E., Watanabe, K., Bryois, J., Williams, D. M., Steinberg, S., Sealock, J., Karlsson, I. K., Hägg, S., Athanasiu, L., Voyle, N., Proitsi, P., Witoelar, A., Stringer, S., Aarsland, D., Almdahl, I. S., Andersen, F., Bergh, S., Bettella, F., Bjornsson, S. & 33 othersBrækhus, A., Bråthen, G., de Leeuw, C., Desikan, R. S., Djurovic, S., Dumitrescu, L., Fladby, T., Hohman, T. J., Jonsson, P. V., Kiddle, S. J., Rongve, A., Saltvedt, I., Sando, S. B., Selbæk, G., Shoai, M., Skene, N. G., Snaedal, J., Stordal, E., Ulstein, I. D., Wang, Y., White, L. R., Hardy, J., Hjerling-Leffler, J., Sullivan, P. F., van der Flier, W. M., Dobson, R., Davis, L. K., Stefansson, H., Stefansson, K., Pedersen, N. L., Ripke, S., Andreassen, O. A. & Posthuma, D., 1 Mar 2019, In : Nature Genetics. 51, 3, p. 404-413 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Meta-Analysis
Alzheimer Disease
Genome
Proxy
Genes

Gradients of structure–function tethering across neocortex

Vázquez-Rodríguez, B., Suárez, L. E., Markello, R. D., Shafiei, G., Paquola, C., Hagmann, P., Van Den Heuvel, M. P., Bernhardt, B. C., Spreng, R. N. & Misic, B., 15 Oct 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 42, p. 21219-21227 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Neocortex
Brain
Population

Identification of common genetic risk variants for autism spectrum disorder

Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, BUPGEN, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23Andme Research Team, Mar 2019, In : Nature Genetics. 51, 3, p. 431-444 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Genome-Wide Association Study
Phenotype
Sample Size
Meta-Analysis
Autism Spectrum Disorder

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 11 Jun 2019, In : Nature Communications. 10, p. 1-18 18 p., 2548.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
methylation
DNA Methylation
Fetal Blood
blood
Blood

Interaction of schizophrenia polygenic risk and cortisol level on pre-adolescent brain structure

Bolhuis, K., Tiemeier, H., Jansen, P. R., Muetzel, R. L., Neumann, A., Hillegers, M. H. J., van den Akker, E. T. L., van Rossum, E. F. C., Jaddoe, V. W. V., Vernooij, M. W., White, T. & Kushner, S. A., Mar 2019, In : Psychoneuroendocrinology. 101, p. 295-303 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Hydrocortisone
Schizophrenia
Brain
Hair
Neuroimaging

Interrogating the genetic determinants of Tourette's syndrome and other tiC disorders through genome-wide association studies

Tourette Association of America International Consortium for Genetics, Gilles de la Tourette GWAS Replication Initiative, Tourette International Collaborative Genetics Study & Psychiatric Genomics Consortium Tourette Syndrome Working Group, 1 Mar 2019, In : American Journal of Psychiatry. 176, 3, p. 217-227 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

File
Tic Disorders
Tourette Syndrome
Genome-Wide Association Study
Tics
Meta-Analysis

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

Understanding Society Scientific Group, EPIC-CVD, GSCAN, Consortium for Genetics of Smoking Behaviour, CHD Exome+ consortium, 7 Jan 2019, In : Molecular Psychiatry. p. 1-18 18 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Genetic Loci
Meta-Analysis
Smoking
Nucleotides
Exome

Multiscale examination of cytoarchitectonic similarity and human brain connectivity

Wei, Y., Scholtens, L. H., Turk, E. & van den Heuvel, M. P., 2019, In : Network neuroscience (Cambridge, Mass.). 3, 1, p. 124-137 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Connectome
Brain
Atlases
Communication

N-Acetyl-Cysteine Supplementation Improves Functional Connectivity Within the Cingulate Cortex in Early Psychosis: A Pilot Study

Mullier, E., Roine, T., Griffa, A., Xin, L., Baumann, P. S., Klauser, P., Cleusix, M., Jenni, R., Alemàn-Gómez, Y., Gruetter, R., Conus, P., Do, K. Q. & Hagmann, P., Aug 2019, In : The international journal of neuropsychopharmacology. 22, 8, p. 478-487 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Gyrus Cinguli
Psychotic Disorders
Cysteine
Brain
Glutathione

Neuron-Glia Interactions Increase Neuronal Phenotypes in Tuberous Sclerosis Complex Patient iPSC-Derived Models

G. Nadadhur, A., Alsaqati, M., Gasparotto, L., Cornelissen-Steijger, P., van Hugte, E., Dooves, S., Harwood, A. J. & Heine, V. M., 8 Jan 2019, In : Stem cell reports. 12, 1, p. 42-56 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Tuberous Sclerosis
Oligodendroglia
Neuroglia
Neurons
Phenotype

Obesity, Brain Volume, and White Matter Microstructure at MRI: A Cross-sectional UK Biobank Study

Dekkers, I. A., Jansen, P. R. & Lamb, H. J., 1 Jun 2019, In : Radiology. 291, 3, p. 763-771 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Adipose Tissue
Obesity
Brain
Anisotropy
Globus Pallidus

Polygenic Scores for Neuropsychiatric Traits and White Matter Microstructure in the Pediatric Population

Jansen, P. R., Muetzel, R. L., Polderman, T. J. C., Jaddoe, V. W., Verhulst, F. C., van der Lugt, A., Tiemeier, H., Posthuma, D. & White, T., Mar 2019, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 3, p. 243-250 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Anisotropy
Intelligence
Pediatrics
Psychiatry
Diffusion Tensor Imaging

Severity of current depression and remission status are associated with structural connectome alterations in major depressive disorder

Repple, J., Mauritz, M., Meinert, S., de Lange, S. C., Grotegerd, D., Opel, N., Redlich, R., Hahn, T., Förster, K., Leehr, E. J., Winter, N., Goltermann, J., Enneking, V., Fingas, S. M., Lemke, H., Waltemate, L., Nenadic, I., Krug, A., Brosch, K., Schmitt, S. & 8 othersStein, F., Meller, T., Jansen, A., Steinsträter, O., Baune, B. T., Kircher, T., Dannlowski, U. & van den Heuvel, M. P., 22 Nov 2019, In : Molecular Psychiatry.

Research output: Contribution to JournalArticleAcademicpeer-review

Connectome
Major Depressive Disorder
Depression
Anisotropy
Brain

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

Koopmans, F., van Nierop, P., Andres-Alonso, M., Byrnes, A., Cijsouw, T., Coba, M. P., Cornelisse, L. N., Farrell, R. J., Goldschmidt, H. L., Howrigan, D. P., Hussain, N. K., Imig, C., de Jong, A. P. H., Jung, H., Kohansalnodehi, M., Kramarz, B., Lipstein, N., Lovering, R. C., MacGillavry, H., Mariano, V. & 53 othersMi, H., Ninov, M., Osumi-Sutherland, D., Pielot, R., Smalla, K. H., Tang, H., Tashman, K., Toonen, R. F. G., Verpelli, C., Reig-Viader, R., Watanabe, K., van Weering, J., Achsel, T., Ashrafi, G., Asi, N., Brown, T. C., De Camilli, P., Feuermann, M., Foulger, R. E., Gaudet, P., Joglekar, A., Kanellopoulos, A., Malenka, R., Nicoll, R. A., Pulido, C., de Juan-Sanz, J., Sheng, M., Südhof, T. C., Tilgner, H. U., Bagni, C., Bayés, À., Biederer, T., Brose, N., Chua, J. J. E., Dieterich, D. C., Gundelfinger, E. D., Hoogenraad, C., Huganir, R. L., Jahn, R., Kaeser, P. S., Kim, E., Kreutz, M. R., McPherson, P. S., Neale, B. M., O'Connor, V., Posthuma, D., Ryan, T. A., Sala, C., Feng, G., Hyman, S. E., Thomas, P. D., Smit, A. B. & Verhage, M., 17 Jul 2019, In : Neuron. 103, 2, p. 217-234.e4 22 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Knowledge Bases
Synapses
Genes
Gene Ontology
Molecular Sequence Annotation

The genetic and environmental relationship between childhood behavioral inhibition and preadolescent anxiety

Bourdon, J. L., Savage, J. E., Verhulst, B., Carney, D. M., Brotman, M. A., Pine, D. S., Leibenluft, E., Roberson-Nay, R. & Hettema, J. M., Feb 2019, In : Twin Research and Human Genetics. 22, 1, p. 48-55 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Anxiety
Anxiety Disorders
Causality
Separation Anxiety
Behavioral Symptoms

The long-term effect of perinatal asphyxia on hippocampal volumes

Annink, K. V., de Vries, L. S., Groenendaal, F., van den Heuvel, M. P., van Haren, N. E. M., Swaab, H., van Handel, M., Jongmans, M. J., Benders, M. J. & van der Aa, N. E., 1 Jan 2019, In : Pediatric Research. 85, 1, p. 43-49 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Asphyxia
Brain Diseases
Long-Term Memory
Intelligence
Linear Models

Topography Impacts Topology: Anatomically Central Areas Exhibit a "High-Level Connector" Profile in the Human Cortex

Zhang, J., Scholtens, L. H., Wei, Y., van den Heuvel, M. P., Chanes, L. & Barrett, L. F., 5 Sep 2019, In : Cerebral Cortex.

Research output: Contribution to JournalArticleAcademicpeer-review

Brain
Cerebral Cortex
2018

Adult mouse eIF2Bϵ Arg191His astrocytes display a normal integrated stress response in vitro

Wisse, L. E., Ter Braak, T. J., Van De Beek, M. C., Van Berkel, C. G. M., Wortel, J., Heine, V. M., Proud, C. G., Van Der Knaap, M. S. & Abbink, T. E. M., 28 Feb 2018, In : Scientific Reports. 8, 1, p. 1-9 9 p., 3773.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Eukaryotic Initiation Factor-2B
Astrocytes
Mutation
White Matter
In Vitro Techniques

Affected astrocytes in the spinal cord of the leukodystrophy vanishing white matter

Leferink, P. S., Breeuwsma, N., Bugiani, M., van der Knaap, M. S. & Heine, V. M., Apr 2018, In : Glia. 66, 4, p. 862-873 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Leukoencephalopathies
Astrocytes
Spinal Cord
Pathology
Oligodendroglia

Age at first birth in women is genetically associated with increased risk of schizophrenia

Ni, G., Gratten, J., Wray, N. R., Lee, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F. & 281 othersBacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chen, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Cloninger, C. R., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., Davidson, M., Davis, K. L., Degenhardt, F., Del Favero, J., Demontis, D., Dikeos, D., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Duan, J., Dudbridge, F., Durmishi, N., Eichhammer, P., Eriksson, J., Escott-Price, V., Essioux, L., Fanous, A. H., Farrell, M. S., Frank, J., Franke, L., Freedman, R., Freimer, N. B., Friedl, M., Friedman, J. I., Fromer, M., Genovese, G., Georgieva, L., Giegling, I., Giusti-Rodríguez, P., Godard, S., Goldstein, J. I., Golimbet, V., Gopal, S., Haan, L. D., Hammer, C., Hamshere, M. L., Hansen, M., Hansen, T., Haroutunian, V., Hartmann, A. M., Henskens, F. A., Herms, S., Hirschhorn, J. N., Hoffmann, P., Hofman, A., Hollegaard, M. V., Hougaard, D. M., Ikeda, M., Joa, I., Juliá, A., Kahn, R. S., Kalaydjieva, L., Karachanak-Yankova, S., Karjalainen, J., Kavanagh, D., Keller, M. C., Kennedy, J. L., Khrunin, A., Kim, Y., Klovins, J., Knowles, J. A., Konte, B., Kucinskas, V., Kucinskiene, Z. A., Kuzelova-Ptackova, H., Kähler, A. K., Laurent, C., Keong, J. L. C., Legge, S. E., Lerer, B., Li, M., Li, T., Liang, K. Y., Lieberman, J., Limborska, S., Loughland, C. M., Lubinski, J., Lönnqvist, J., Macek, M., Magnusson, P. K. E., Maher, B. S., Maier, W., Mallet, J., Marsal, S., Mattheisen, M., Mattingsdal, M., McCarley, R. W., McDonald, C., McIntosh, A. M., Meier, S., Meijer, C. J., Melegh, B., Melle, I., Mesholam-Gately, R. I., Metspalu, A., Michie, P. T., Milani, L., Milanova, V., Mokrab, Y., Morris, D. W., Mors, O., Murphy, K. C., Murray, R. M., Myin-Germeys, I., Müller-Myhsok, B., Nelis, M., Nenadic, I., Nertney, D. A., Nestadt, G., Nicodemus, K. K., Nikitina-Zake, L., Nisenbaum, L., Nordin, A., O'callaghan, E., O'dushlaine, C., O'neill, F. A., Oh, S. Y., Olincy, A., Olsen, L., Os, J. V., Pantelis, C., Papadimitriou, G. N., Papiol, S., Parkhomenko, E., Pato, M. T., Paunio, T., Pejovic-Milovancevic, M., Perkins, D. O., Pietiläinen, O., Pimm, J., Pocklington, A. J., Powell, J., Price, A., Pulver, A. E., Purcell, S. M., Quested, D., Rasmussen, H. B., Reichenberg, A., Reimers, M. A., Richards, A. L., Roffman, J. L., Roussos, P., Ruderfer, D. M., Salomaa, V., Sanders, A. R., Schall, U., Schubert, C. R., Schulze, T. G., Schwab, S. G., Scolnick, E. M., Scott, R. J., Seidman, L. J., Shi, J., Sigurdsson, E., Silagadze, T., Silverman, J. M., Sim, K., Slominsky, P., Smoller, J. W., So, H. C., Spencer, C. C. A., Stahl, E. A., Stefansson, H., Steinberg, S., Stogmann, E., Straub, R. E., Strengman, E., Strohmaier, J., Stroup, T. S., Subramaniam, M., Suvisaari, J., Svrakic, D. M., Szatkiewicz, J. P., Söderman, E., Thirumalai, S., Toncheva, D., Tosato, S., Veijola, J., Waddington, J., Walsh, D., Wang, D., Wang, Q., Webb, B. T., Weiser, M., Wildenauer, D. B., Williams, N. M., Williams, S., Witt, S. H., Wolen, A. R., Wong, E. H. M., Wormley, B. K., Xi, H. S., Zai, C. C., Zheng, X., Zimprich, F., Stefansson, K., Visscher, P. M., Adolfsson, R., Andreassen, O. A., Blackwood, D. H. R., Bramon, E., Buxbaum, J. D., Børglum, A. D., Cichon, S., Darvasi, A., Domenici, E., Ehrenreich, H., Esko, T., Gejman, P. V., Gill, M., Gurling, H., Hultman, C. M., Iwata, N., Jablensky, A. V., Jönsson, E. G., Kendler, K. S., Kirov, G., Knight, J., Lencz, T., Levinson, D. F., Li, Q. S., Liu, J., Malhotra, A. K., McCarroll, S. A., McQuillin, A., Moran, J. L., Mortensen, P. B., Mowry, B. J., Nöthen, M. M., Ophoff, R. A., Owen, M. J., Palotie, A., Pato, C. N., Petryshen, T. L., Posthuma, D., Rietschel, M., Riley, B. P., Rujescu, D., Sham, P. C., Sklar, P., Clair, D. S., Weinberger, D. R., Wendland, J. R., Werge, T., Daly, M. J., Sullivan, P. F. & O'donovan, M. C., 5 Jul 2018, In : Scientific Reports. 8, p. 1-14 14 p., 10168.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Birth Order
Schizophrenia
Parents
Mental Health
Genetic Heterogeneity

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

de Jong, S., Diniz, M. J. A., Saloma, A., Gadelha, A., Santoro, M. L., Ota, V. K., Noto, C., Curtis, C., Newhouse, S. J., Patel, H., Hall, L. S., O`Reilly, P. F., Belangero, S. I., Bressan, R. A., Breen, G. & Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, 8 Oct 2018, In : Communications biology. 1, p. 1-10 10 p., 163.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
behavior disorders
Major Depressive Disorder
Bipolar Disorder
Psychiatry
Pedigree

A tutorial on conducting genome-wide association studies: Quality control and statistical analysis

Marees, A. T., de Kluiver, H., Stringer, S., Vorspan, F., Curis, E., Marie-Claire, C. & Derks, E. M., Jun 2018, In : International Journal for Methods in Psychiatric Research . 27, 2, p. 1-10 10 p., e1608.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-Wide Association Study
Quality Control
Single Nucleotide Polymorphism
Software
Social Sciences

Axonal abnormalities in vanishing white matter

Klok, M. D., Bugiani, M., de Vries, S. I., Gerritsen, W., Breur, M., van der Sluis, S., Heine, V. M., Kole, M. H. P., Baron, W. & van der Knaap, M. S., 1 Apr 2018, In : Annals of Clinical and Translational Neurology. 5, 4, p. 429-444 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Astrocytes
Axons
Myelin Sheath
Prosencephalon
Coculture Techniques

Bergmann glia translocation: a new disease marker for vanishing white matter identifies therapeutic effects of Guanabenz treatment

Dooves, S., Bugiani, M., Wisse, L. E., Abbink, T. E. M., van der Knaap, M. S. & Heine, V. M., Jun 2018, In : Neuropathology and Applied Neurobiology. 44, 4, p. 391-403 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Guanabenz
Therapeutic Uses
Neuroglia
Pathology
Therapeutics

Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals

Coleman, J. R. I., Bryois, J., Gaspar, H. A., Jansen, P. R., Savage, J. E., Skene, N., Plomin, R., Muñoz-Manchado, A. B., Linnarsson, S., Crawford, G., Hjerling-Leffler, J., Sullivan, P. F., Posthuma, D. & Breen, G., 8 Mar 2018, In : Molecular Psychiatry. 2018, p. 1-16 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Genetic Loci
Intelligence
Meta-Analysis
Genome-Wide Association Study
Genes

Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families

Boomsma, D. I., Ligthart, R. S. L., Posthuma, D. & 23Andme Research Team, 16 May 2018, In : Neuron. 98, 4, p. 743-753.e4

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Migraine Disorders
Migraine without Aura
Migraine with Aura
Genome-Wide Association Study
Population

Comparative primate connectomics

Rilling, J. K. & Van Den Heuvel, M. P., Aug 2018, In : Brain, Behavior and Evolution. 91, 3, p. 170-179 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Connectome
Primates
Brain
Language
Diffusion Tensor Imaging

Conditional and interaction gene-set analysis reveals novel functional pathways for blood pressure

de Leeuw, C. A., Stringer, S., Dekkers, I. A., Heskes, T. & Posthuma, D., 14 Sep 2018, In : Nature Communications. 9, p. 1-13 13 p., 3768.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
blood pressure
Blood pressure
genes
Genes
Blood Pressure

Cross-species evidence of interplay between neural connectivity at the micro- and macroscale of connectome organization in human, mouse and rat brain

Scholtens, L. H., Feldman Barrett, L. & van den Heuvel, M. P., 14 Dec 2018, In : Brain Connectivity. 8, 10, p. 595-603 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Connectome
Brain
Neurons
Communication
Diffusion Magnetic Resonance Imaging

Deviations from Expectations: A Commentary on Aliev et al.

van der Sluis, S., Vroom, C. R. & Dolan, C. V., Mar 2018, In : Behavior Genetics. 48, 2, p. 168-172 5 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access