Innovations in Human Health & Life Sciences

Fingerprint Dive into the research topics where Innovations in Human Health & Life Sciences is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Liver Chemical Compounds
Glutathione Transferase Chemical Compounds
Oxidoreductases Chemical Compounds
Floxacillin Chemical Compounds
Metabolites Chemical Compounds
Bibliometrics Medicine & Life Sciences
NAD Chemical Compounds
Hydroxylation Chemical Compounds

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Research Output 2018 2018

  • 6 Article
  • 1 Inaugural speech
  • 1 Review article
  • 1 PhD Thesis - Research VU, graduation VU

Acetaminophen reduces the protein levels of high affinity amino acid permeases and causes tryptophan depletion

Huseinovic, A., Dekker, S. J., Boogaard, B., Vermeulen, N. P. E., Kooter, J. M. & Vos, J. C., Oct 2018, In : Amino Acids. 50, 10, p. 1377-1390 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Amino Acid Transport Systems
Acetaminophen
Tryptophan
Proteins
Yeast

A combined computational and experimental study on selective flucloxacillin hydroxylation by cytochrome P450 BM3 variants

Luirink, R. A., Dekker, S. J., Capoferri, L., Kuiper, C. L., Janssen, L. F. H., Ari, M. E., Vermeulen, N. P. E., Vos, J. C., Commandeur, J. N. M. & Geerke, D. P., Jul 2018, In : Journal of Inorganic Biochemistry. 184, p. 115-122 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Floxacillin
Hydroxylation
Cytochrome P-450 Enzyme System
Metabolites
Enzymes
Open Access
File

Effect of UGT2B7*2 and CYP2C8*4 polymorphisms on diclofenac metabolism

Lazarska, K. E., Dekker, S. J., Vermeulen, N. P. E. & Commandeur, J. N. M., 1 Mar 2018, In : Toxicology Letters. 284, 1 March, p. 70-78 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Diclofenac
Polymorphism
Metabolism
Liver
Chemical and Drug Induced Liver Injury
High performance liquid chromatography
Glutathione Transferase
Liver
Sulfates
Assays