Fingerprint Dive into the research topics where Medicinal chemistry is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Ligands Medicine & Life Sciences
G-Protein-Coupled Receptors Medicine & Life Sciences
Histamine Medicine & Life Sciences
Chemokine Receptors Medicine & Life Sciences
Histamine Receptors Medicine & Life Sciences
Histamine H3 Receptors Medicine & Life Sciences
Single-Domain Antibodies Medicine & Life Sciences
Pharmacology Medicine & Life Sciences

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Profiles

No photo of Ilze Adlere

Ilze Adlere, MSc

Person: Academic

20192019
No photo of J.P. Bebelman

J.P. Bebelman

Person: Academic

19972019
No photo of Nick Bergkamp

Nick Bergkamp

Person: Academic

20192019
No photo of Vladimir Bobkov

Vladimir Bobkov

Person: Academic

20182019
No photo of A.H. Boer, de

dr. ir. A.H. de Boer

Person: Academic

19872019

Research Output 1985 2020

Real-time imaging of multivesicular body–plasma membrane fusion to quantify exosome release from single cells

Bebelman, M. P., Bun, P., Huveneers, S., van Niel, G., Pegtel, D. M. & Verweij, F. J., Jan 2020, In : Nature Protocols. 15, 1, p. 102-121 20 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Exosomes
Membrane Fusion
Fusion reactions
Multivesicular Bodies
Membranes

4-(3-Aminoazetidin-1-yl)pyrimidin-2-amines as High-Affinity Non-imidazole Histamine H3 Receptor Agonists with in Vivo Central Nervous System Activity

Wágner, G., Mocking, T. A. M., Arimont, M., Provensi, G., Rani, B., Silva-Marques, B., Latacz, G., Da Costa Pereira, D., Karatzidou, C., Vischer, H. F., Wijtmans, M., Kieć-Kononowicz, K., De Esch, I. J. P. & Leurs, R., 1 Nov 2019, In : Journal of Medicinal Chemistry. 19 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Histamine H3 Receptors
Histamine Agonists
Amines
Central Nervous System
Cytochrome P-450 Enzyme System

Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors

de Heuvel, E., Singh, A. K., Edink, E., van der Meer, T., van der Woude, M., Sadek, P., Krell-Jørgensen, M. P., van den Bergh, T., Veerman, J., Caljon, G., Kalejaiye, T. D., Wijtmans, M., Maes, L., de Koning, H. P., Jan Sterk, G., Siderius, M., de Esch, I. J. P., Brown, D. G. & Leurs, R., 18 Jun 2019, In : Bioorganic and Medicinal Chemistry. p. 1-15 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Trypanosoma brucei brucei
Phosphoric Diester Hydrolases
Parasites
Cyclic Nucleotides
Cytotoxicity

Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2)

de Heuvel, E., Singh, A. K., Boronat, P., Kooistra, A. J., van der Meer, T., Sadek, P., Blaazer, A. R., Shaner, N. C., Bindels, D. S., Caljon, G., Maes, L., Sterk, G. J., Siderius, M., Oberholzer, M., de Esch, I. J. P., Brown, D. G. & Leurs, R., 15 Sep 2019, In : Bioorganic and Medicinal Chemistry. 27, 18, p. 4013-4029 17 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Phosphodiesterase Inhibitors
Parasites
African Trypanosomiasis
Trypanosoma brucei brucei
Trypanosomiasis

Analysis of Arabidopsis thaliana HKT1 and Eutrema salsugineum/botschantzevii HKT1;2 Promoters in Response to Salt Stress in Athkt1:1 Mutant

Nawaz, I., Iqbal, M., Hakvoort, H. W. J., de Boer, A. H. & Schat, H., 1 Jun 2019, In : Molecular Biotechnology. 61, 6, p. 442-450 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Arabidopsis
Salts
Agricultural Crops
Cathode ray tubes
Level control

Activities 1995 2013

  • 124 Lecture / Presentation

Knowledge Representation in Scientific Models and their Publications : a Case Study

M.G. de Vos (Speaker), W.R. van Hage (Speaker), J. Wielemaker (Speaker), A. Schreiber (Speaker)
2013

Activity: Lecture / PresentationAcademic

File

Design of the BiographyNet schema: Multiple views and provenance

C.J. Ockeloen (Speaker), A.S. Fokkens-Zwirello (Speaker), S. ter Braake (Speaker), P.T.J.M. Vossen (Speaker), S. Legene (Speaker), V. de Boer (Speaker), A.Th. Schreiber (Speaker)
28 Nov 2013

Activity: Lecture / PresentationAcademic

Drug Metabolism: computational approaches to predict drug metabolism.

J.H.N. Meerman (Speaker)
1999

Activity: Lecture / PresentationAcademic

Qualitative structure-activity relationships for inverse agonism by H2 antagonists,

A.E. Alewijnse (Speaker)
1999

Activity: Lecture / PresentationAcademic

Prizes

FIGON DMD Poster Prize

Tian Shu Fan (Recipient), 2015

PrizeAcademic

KNCV Poster Prize

Tian Shu Fan (Recipient), 2015

PrizeAcademic