Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Histamine Medicine & Life Sciences
Ligands Medicine & Life Sciences
G-Protein-Coupled Receptors Medicine & Life Sciences
Chemokine Receptors Medicine & Life Sciences
Histamine Receptors Medicine & Life Sciences
Cytochrome P-450 Enzyme System Medicine & Life Sciences
Rats Chemical Compounds
Histamine H3 Receptors Medicine & Life Sciences

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Profiles

No photo of Ilze Adlere

Ilze Adlere

Person: Academic

No photo of Marta Arimont Segura

Marta Arimont Segura

Person: Academic

No photo of J.P. Bebelman

J.P. Bebelman

19972018
Photo of Maarten Bebelman
20182018
No photo of Vladimir Bobkov

Vladimir Bobkov

Person: Academic

Research Output 1985 2018

4-Hydroxypiperidines and their flexible 3-(amino)propyloxy analogues as non-imidazole histamine H3 receptor antagonist: Further structure-activity relationship exploration and in vitro and in vivo pharmacological evaluation

Olszewska, B., Stasiak, A., McNaught Flores, D., Fogel, W. A., Leurs, R. & Walczyński, K., Apr 2018, In : International Journal of Molecular Sciences. 19, p. 1-19 19 p., 1243

Research output: Contribution to JournalArticleAcademicpeer-review

histamines
Structure-Activity Relationship
Histamine
Neurotransmitter Agents
Rats

A Structural Framework for GPCR Chemogenomics: What’s In a Residue Number?

Vass, M., Kooistra, A. J., Verhoeven, S., Gloriam, D., de Esch, I. J. P. & de Graaf, C., 2018, Computational Methods for GPCR Drug Discovery. Heifetz, A. (ed.). Humana Press Inc, p. 73-113 41 p. (Methods in Molecular Biology; vol. 1705)

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

G-Protein-Coupled Receptors
Binding Sites
Ligands
Workflow
Mutation

Biogenesis and function of extracellular vesicles in cancer

Bebelman, M. P., Smit, M. J., Pegtel, D. M. & Baglio, S. R., Aug 2018, In : Pharmacology and Therapeutics. 188, p. 1-11 11 p.

Research output: Contribution to JournalReview articleAcademicpeer-review

Exosomes
Neoplasms
Biological Phenomena
Endosomes
Growth

Chemical Diversity in the G Protein-Coupled Receptor Superfamily

Vass, M., Kooistra, A. J., Yang, D., Stevens, R. C., Wang, M. W. & de Graaf, C., 1 May 2018, In : Trends in Pharmacological Sciences. 39, 5, p. 494-512 19 p.

Research output: Contribution to JournalReview articleAcademicpeer-review

G-Protein-Coupled Receptors
Ligands
Cell signaling
Chemical compounds
Modulators

Correction: Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling

Verweij, F. J. , Bebelman, M. P. , Jimenez, C. R. , Garcia-Vallejo, J. J. , Janssen, H. , Neefjes, J. , Knol, J. C. , de Goeij-de Haas, R. , Piersma, S. R. , Baglio, S. R. , Verhage, M. , Middeldorp, J. M. , Zomer, A. , van Rheenen, J. , Coppolino, M. G. , Hurbain, I. , Raposo, G. , Smit, M. J. , Toonen, R. F. G. , van Niel, G. & 1 others Pegtel, D. M., 23 Jan 2018, In : Journal of Cell Biology.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Activities 1995 2013

  • 124 Lecture / Presentation

Design of the BiographyNet schema: Multiple views and provenance

Ockeloen, C. J. (Speaker), Fokkens, A. S. (Speaker), S. ter Braake (Speaker), Vossen, P. T. J. M. (Speaker), Legene, S. (Speaker), de Boer, V. (Speaker), Schreiber, A. T. (Speaker)
28 Nov 2013

Activity: Lecture / PresentationAcademic

Knowledge Representation in Scientific Models and their Publications : a Case Study

M.G. de Vos (Speaker), W.R. van Hage (Speaker), Wielemaker, J. (Speaker), A. Schreiber (Speaker)
2013

Activity: Lecture / PresentationAcademic

File

Qualitative structure-activity relationships for inverse agonism by H2 antagonists,

A.E. Alewijnse (Speaker)
1999

Activity: Lecture / PresentationAcademic

Inverse agonism of histamine H1 antagonists,

R.A. Bakker (Speaker)
1999

Activity: Lecture / PresentationAcademic

Prizes

FIGON DMD Poster Prize

T.S. Fan (Recipient), 2015

Prize: Prize / AwardAcademic

KNCV Poster Prize

T.S. Fan (Recipient), 2015

Prize: Prize / AwardAcademic