Projects per year
Fingerprint
Collaborations and top research areas from the last five years
Projects
- 1 Finished
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ONCORNET2.0: Horizon2020 ONCOgenic Receptor Network of Excellence and Training 2.0
van Muijlwijk-Koezen, J. & Smit, M.
1/02/20 → 31/01/24
Project: Research
Research output
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Multiplexed experimental strategies for fragment library screening against challenging drug targets using SPR biosensors
FitzGerald, E. A., Vagrys, D., Opassi, G., Klein, H. F., Hamilton, D. J., Talibov, V. O., Abramsson, M., Moberg, A., Lindgren, M. T., Holmgren, C., Davis, B., O'Brien, P., Wijtmans, M., Hubbard, R. E., de Esch, I. J. P. & Danielson, U. H., Jan 2024, In: SLAS Discovery. 29, 1, p. 40-51 12 p.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Nanobodies targeting human and viral chemokine receptors
Bergkamp, N. D., 23 Feb 2024, 260 p.Research output: PhD Thesis › PhD-Thesis - Research and graduation internal
Open AccessFile119 Downloads (Pure) -
Pharmacological Characterization of the Zebrafish (Danio Rerio) Histamine H1 Receptor Reveals the Involvement of the Second Extracellular Loop in the Binding of Histamine
McNaught-Flores, D. A., Kooistra, A. J., Chen, Y. C., Arias-Montano, J. A., Panula, P. & Leurs, R., 10 Jan 2024, In: Molecular Pharmacology. 105, 2, p. 84-96 13 p.Research output: Contribution to Journal › Article › Academic › peer-review
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Small Molecule Fluorescent Ligands for the Atypical Chemokine Receptor 3 (ACKR3)
Dekkers, S., Comez, D., Karsai, N., Arimont-Segura, M., Canals, M., Caspar, B., de Graaf, C., Kilpatrick, L. E., Leurs, R., Kellam, B., Hill, S. J., Briddon, S. J. & Stocks, M. J., 11 Jan 2024, In: ACS medicinal chemistry letters. 15, 1, p. 143-148 6 p.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
An Automated, Open-Source Workflow for the Generation of (3D) Fragment Libraries
Dekker, T., Janssen, M. A. C. H., Sutherland, C., Aben, R. W. M., Scheeren, H. W., Blanco-Ania, D., Rutjes, F. P. J. T., Wijtmans, M. & de Esch, I. J. P., 11 May 2023, In: ACS medicinal chemistry letters. 14, 5, p. 583-590 8 p.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access
Courses
Activities
- 124 Lecture / Presentation
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Knowledge Representation in Scientific Models and their Publications : a Case Study
M.G. de Vos (Speaker), W.R. van Hage (Speaker), J. Wielemaker (Speaker) & A. Schreiber (Speaker)
2013Activity: Lecture / Presentation › Academic
File -
Design of the BiographyNet schema: Multiple views and provenance
C.J. Ockeloen (Speaker), A.S. Fokkens-Zwirello (Speaker), S. ter Braake (Speaker), P.T.J.M. Vossen (Speaker), S. Legene (Speaker), V. de Boer (Speaker) & A.Th. Schreiber (Speaker)
28 Nov 2013Activity: Lecture / Presentation › Academic
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Changed insights in receptor mechanisms and the consequences for Medicine Research.
H. Timmerman (Speaker)
1999Activity: Lecture / Presentation › Academic
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A third generation antihistamines: feasible or a dream?
H. Timmerman (Speaker)
1999Activity: Lecture / Presentation › Academic
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The never ending story of the H1 antihistamines
H. Timmerman (Speaker)
1999Activity: Lecture / Presentation › Academic
Prizes
Datasets
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PDEStrIAn: A phosphodiesterase structure and ligand interaction annotated database as a tool for structure-based drug design
Jansen, C. (Contributor), Kooistra, A. J. (Contributor), Kanev, G. K. (Contributor), Leurs, R. (Contributor), de Esch, I. (Contributor) & De Graaf, C. (Contributor), Zenodo, 2016
DOI: 10.5281/zenodo.45774, https://zenodo.org/record/45774
Dataset
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PDEStrIAn: A phosphodiesterase structure and ligand interaction annotated database as a tool for structure-based drug design
Kooistra, A. J. (Contributor), Leurs, R. (Contributor), Kanev, G. K. (Contributor), de Esch, I. (Contributor), de Graaf, C. (Contributor) & Jansen, C. (Contributor), Unknown Publisher, 8 Feb 2016
DOI: 10.5281/zenodo.45774, https://zenodo.org/record/45774
Dataset
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Aminergic G protein-coupled receptor (GPCR) mutation data set
Vass, M. (Contributor), Podlewska, S. (Contributor), de Esch, I. (Contributor), Bojarski, A. J. (Contributor), Leurs, R. (Contributor), Kooistra, A. J. (Contributor), De Graaf, C. (Contributor) & Kuhne, S. (Contributor), Zenodo, 2016
DOI: 10.5281/zenodo.58104, https://zenodo.org/record/58104
Dataset
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CCDC 244630: Experimental Crystal Structure Determination
Kitbunnadaj, R. (Contributor), Zuiderveld, O. P. (Contributor), de Esch, I. (Contributor), Vollinga, R. C. (Contributor), Bakker, R. (Contributor), Lutz, M. (Contributor), Spek, A. L. (Contributor), Cavoy, E. (Contributor), Deltent, M. (Contributor), Menge, W. M. P. B. (Contributor), Timmerman, H. (Contributor) & Leurs, R. (Contributor), Unknown Publisher, 1 Jan 2004
DOI: 10.5517/cc86k99, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc86k99&sid=DataCite
Dataset
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Secretin-like class B G protein-coupled receptor (GPCR) mutation data set
De Graaf, C. (Contributor), Zenodo, 2016
DOI: 10.5281/zenodo.60790, https://zenodo.org/record/60790
Dataset