Research Output 1985 2020

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PhD Thesis - Research VU, graduation VU
1989

Thiols in oxidative stress: some implications for catecholamine toxicity

Haenen, G. R. M. M., 1989, 182 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

1992

Computational chemistry in biotransformational and toxicological research: mechanisms of oxidation by and active site structure of cytochromes P450

Koymans, L. M. H., 1992, 199 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

1993

The role of cytochrome P450 in the reductive bioactivation of cytostatic quinones

Goeptar, A. R., 1993, 180 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

1995

Anesthesia and oxidative stress.

Aarts, L. P. H. J., 1995, 145 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Disposition and biological effects of fotemustine, a new anticancer agent. A molecular toxicological study in rats and humans.

Brakenhoff, J. P. G., 1995, 215 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Dynamic regulation of the histamine H1 and H2 receptors

Smit, M. J., 1995

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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Histamine H₁-receptor agonists and antagonists: molecular modeling and drug design

ter Laak, A. M., 1995, 172 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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Interactions between reactive oxygen species and histamine receptor agonists and antagonists.

Ching, T. L., 1995, Amsterdam. 102 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

New ligands of the histamine H3 receptor

Vollinga, R. C., 1995, 203 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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1996

A new molecular mechanism for the activation of the histamine H₂ receptor.

Nederkoorn, P. H. J., 1996, Amsterdam. 254 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Flavonoids as protective agents against doxorubicin-induced cardiotoxicity.

van Acker, S. A. B. E., 1996, Amsterdam. 211 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

The histamine H3 receptor in the rat brain: Pharmacological and (patho)physiological aspects

de Fátima Alves Rodrigues, A., 1996, Amsterdam. 152 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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Total synthesis of the natural peptide-mimic cyclotheonamide B and analogues.

Bastiaans, H. M. M., 1996, 163 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

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1997

Histamine H3-receptors in the central nervous systems of rats and mice

Jansen, F. P., 1997

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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Mercapturic acids in biological monotoring; Applications to industrial chemicals.

de Rooij, B. M., 1997

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Molecular recognition of the leukotriene CysLT1 receptor. Synthesis, SAR and molecular modelling of carboxyflavonoids.

Zwaagstra, M. E., 1997

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

1998

Development of non-invasive biomarkers for free radical induced damage. Model studies in experimental animals and applications in humans.

de Zwart, L. L., 1998, Amsterdam: Zwart, L.L.. 239 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Inter-individual variability in drug metabolism. Model studies with 1,2-dibromoethane using in vitro approaches and physiologically based pharmacokinetic modeling.

Wormhoudt, L. W., 1998, Amsterdam: L.W. Wormhoudt. 294 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Synthesis and characterization of 18F and 123I labeled antagonists of the histamine H3 receptor as putative PET and SPECT ligands.

Windhorst, A. D., 1998, Alphen a/d rijn: A.D. Windhorst. 135 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

1999

Modulation of the Nitric Oxide system,

Paquay, J. B. G., 1999

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Novel phosphodiesterase inhibitors.

van der Meij, M., 1999

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

2000

Synthesis, structure activity relationships and molecular modelling of histamine H3 receptor ligands

de Esch, I. J. P., 2000

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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2001

antagonists for the human adenosine A3 receptor

van Muijlwijk-Koezen, J. E., 2001

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

the histamine H2 receptor: constitutive activity and inverse agonism

Alewijnse, A. E., 2001

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

2002

Modulating the expression of biotransformation enzymes: studies with enzyme inducers and antisense oligonucleotides

Hoen, P-B. ., 2002, 175 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

2003

High-Throughput Screening and Molecular Modeling of Biotransformation Enzymes

Venhorst, J., 2003

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

The Solid-phase synthesis of substituted imidazoles via a scaffold approach

Gelens, E., 2003, 192 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

2004

Development and application to HIV inhibitor design

Vinkers, H. M., 2004

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

2006

Gamma-herpesvirus-encoded G-protein-coupled receptors

Verzijl, D., 2006

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Mutational analysis of the human histamine H1 receptor

Bruysters, MWP., 2006

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Probing human cytochromes P450: mutational and spectroscopic analysis of CYP2D6

Keizers, P. H. J., 2006

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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2007

Design and synthesis of small nonpeptidergic ligands for the human cytomegalovirus-encoded receptor US28

Hulshof, J. W., 2007

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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Molecular pharmacology of the human histamine H4 receptor

van Rijn, R. M., 2007, 216 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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2009

Design and Synthesis of New Histamine H4 Receptor Ligands

Smits, R. A., 2009

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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Herpesvirus-Encoded G Protein-Coupled Receptors as Modulators of Cellular Signaling Pathways

Maussang Detaille, D. A. B., 2009

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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Ligand-receptor interactions of the histamine H4 receptor

Lim, H. D., 2009

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

2010

Design, synthesis and pharmacological evaluation of non-peptidergic ligands for the human CXCR3 receptor

Storelli, S., 2010

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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Molecular aspects of the histamine H1 receptor

Sansuk, K., 2010

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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Selective Derivatization Reagents for the Determination of Oxidative Stress Biomarkers by Liquid Chromatography-Mass Spectrometry

Eggink, M., 2010

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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The acetylcholine binding protein as a template for the ligand binding domains of the homologous nicotinic receptors

Akdemir, A., 2010, 201 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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2011

Exploring fragment space: Library construction, screening and fragment growing

de Kloe, G. E., 2011

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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Exploring the Chemokine Receptor CXCR2: Ligand Recognition and Response

de Kruijf, P., 2011, 177 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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Structure-based design of AChBP ligands, new insights and applications

Edink, E. S., 2011

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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2012

Chemokine Receptors CXCR3 and CXCR7: Allosteric Ligand Binding, Biased Signaling, and Receptor Regulation

Scholten, D. J., 2012

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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Computational Studies of the Histamine H4 Receptor-Ligand Interactions

Istyastono, E. P., 2012

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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Dimerization and signaling of the chemokine receptors CXCR3 and CCX-CKR

Watts, A. O., 2012

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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Fragment-based drug discovery approaches towards novel 5-HT3 receptor ligands

Verheij, M. H. P., 2012

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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Oncomodulatory properties of the human cytomegalovirus-encoded receptors US28 and UL33

Langemeijer, E. V., 2012

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
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