Molecular and Computational Toxicology

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Cytochrome P-450 Enzyme System Medicine & Life Sciences
Rats Chemical Compounds
Metabolites Chemical Compounds
Cytochrome P-450 CYP2D6 Medicine & Life Sciences
Liver Chemical Compounds
Toxicity Chemical Compounds
Acetaminophen Medicine & Life Sciences
Glutathione Transferase Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Profiles

No photo of W. Cai

W. Cai

No photo of Giada Carta

Giada Carta

Person: Academic

20152018
Photo of J.N.M. Commandeur
19872018

Research Output 1977 2018

Acetaminophen reduces the protein levels of high affinity amino acid permeases and causes tryptophan depletion

Huseinovic, A., Dekker, S. J., Boogaard, B., Vermeulen, N. P. E., Kooter, J. M. & Vos, J. C., Oct 2018, In : Amino Acids. 50, 10, p. 1377-1390 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Amino Acid Transport Systems
Acetaminophen
Tryptophan
Proteins
Yeast

A combined computational and experimental study on selective flucloxacillin hydroxylation by cytochrome P450 BM3 variants

Luirink, R. A., Dekker, S. J., Capoferri, L., Kuiper, C. L., Janssen, L. F. H., Ari, M. E., Vermeulen, N. P. E., Vos, J. C., Commandeur, J. N. M. & Geerke, D. P., Jul 2018, In : Journal of Inorganic Biochemistry. 184, p. 115-122 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Floxacillin
Hydroxylation
Cytochrome P-450 Enzyme System
Metabolites
Enzymes

Advanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systems

Pamies, D., Bal-Price, A., Chesné, C., Coecke, S., Dinnyes, A., Eskes, C., Grillari, R., Gstraunthaler, G., Hartung, T., Jennings, P., Leist, M., Martin, U., Passier, R., Schwamborn, J. C., Stacey, G. N., Ellinger-Ziegelbauer, H. & Daneshian, M., 13 Apr 2018, In : Altex. 35, 3

Research output: Contribution to JournalArticleAcademicpeer-review

Organoids
Stem Cells
Cell Culture Techniques
Technology
Induced Pluripotent Stem Cells

Comparison of base-line and chemical-induced transcriptomic responses in HepaRG and RPTEC/TERT1 cells using TempO-Seq

Limonciel, A., Ates, G., Carta, G., Wilmes, A., Watzele, M., Shepard, P. J., VanSteenhouse, H. C., Seligmann, B., Yeakley, J. M., van de Water, B., Vinken, M. & Jennings, P., Aug 2018, In : Archives of Toxicology. 92, 8, p. 2517-2531 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Workflow
Toxic Actions
Costs and Cost Analysis
Glycolysis
Computational Biology

Differentiation of human iPSCs into functional podocytes

Rauch, C., Feifel, E., Kern, G., Murphy, C., Meier, F., Parson, W., Beilmann, M., Jennings, P., Gstraunthaler, G. & Wilmes, A., Sep 2018, In : PLoS ONE. e0203869

Research output: Contribution to JournalArticleAcademicpeer-review

Activities 1996 2014

  • 125 Lecture / Presentation

Demonstration projects for sustainable energy

Bossink, B. A. G. (Speaker)
19 May 2014

Activity: Lecture / PresentationAcademic

Science, Business and Innovation

Bossink, B. A. G. (Speaker)
28 Apr 2014

Activity: Lecture / PresentationAcademic

Identification and characterisation of Hsp70-containing protein complexes from Saccharomyces cerevisiae

P. van Breugel (Speaker)
14 Oct 2002

Activity: Lecture / PresentationAcademic

alternative RNA processing in its 1 requires RNa family member rex4p

Vos, J. C. (Speaker), E.A. Eppens (Speaker), A.W. Faber (Speaker), H.A. Raue (Speaker)
31 May 2001

Activity: Lecture / PresentationAcademic

The final steps in processing of rRNA in yeast

T.H. Geerlings (Speaker)
4 May 2001

Activity: Lecture / PresentationAcademic

Prizes

AIMMS NWO STAR grant antimicrobial research

S. Ortega Ugalde (Recipient), 2015

Prize: Prize / AwardAcademic

Cefic Long-Range Research Initiative Award

Alice Limonciel (Recipient), 2015

Prize: Prize / AwardAcademic

honors and awards

Lush Young Researcher Prize

Alice Limonciel (Recipient), 2013

Prize: Prize / AwardAcademic

Safety testing
Animals

Otto Kraupp Preis

A. Wilmes (Recipient), 6 Jun 2017

Prize: Prize / AwardAcademic

Recognitions (selected):

N.P.E. Vermeulen (Recipient), 1985

Prize: Prize / AwardAcademic

Republic of Korea
Berlin
Germany
Research
Pharmaceutical Preparations

Press / Media

TeamNL

B.A.G. Bossink

13/12/15

1 media contribution

Press/Media: Other

TeamNL

B.A.G. Bossink

6/12/15

1 media contribution

Press/Media: Other

TeamNL

B.A.G. Bossink

29/11/15

1 media contribution

Press/Media: Other

TeamNL

B.A.G. Bossink

22/11/15

1 media contribution

Press/Media: Other

TeamNL

B.A.G. Bossink

15/11/15

1 media contribution

Press/Media: Other