Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Escherichia coli Medicine & Life Sciences
Membrane Proteins Medicine & Life Sciences
Proteins Medicine & Life Sciences
Membranes Medicine & Life Sciences
Mycobacterium Medicine & Life Sciences
Signal Recognition Particle Medicine & Life Sciences
Mycobacterium marinum Medicine & Life Sciences
Paracoccus denitrificans Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Profiles

Photo of Wilbert Bitter

Wilbert Bitter

Person: Academic

20032019
No photo of C.M. Bunduc

C.M. Bunduc

Person: Academic

20172017
No photo of Merel Damen

Merel Damen

Person: Academic

20192019
No photo of James Luke Gallant

James Luke Gallant

Person: Academic

Research Output 1978 2019

Integrated transcriptomic and proteomic analysis of pathogenic mycobacteria and their esx-1 mutants reveal secretion-dependent regulation of ESX-1 substrates and WhiB6 as a transcriptional regulator

Abdallah, A. M., Weerdenburg, E. M., Guan, Q., Ummels, R., Borggreve, S., Adroub, S. A., Malas, T. B., Naeem, R., Zhang, H., Otto, T. D., Bitter, W. & Pain, A., 2019, In : PLoS ONE. 14, 1, p. e0211003

Research output: Contribution to JournalArticleAcademicpeer-review

Mycobacterium
transcriptomics
Proteomics
proteomics
transcription factors

Protease and transmembrane domain of the type VII secretion mycosin protease determine system-specific functioning in mycobacteria

van Winden, V. J. C., Damen, M. P. M., Ummels, R., Bitter, W. & Houben, E. N. G., 28 Jan 2019, In : Journal of Biological Chemistry.

Research output: Contribution to JournalArticleAcademicpeer-review

Mycobacterium
Peptide Hydrolases
Mycobacterium marinum
Membranes
Stabilization

Accelerating early antituberculosis drug discovery by creating mycobacterial indicator strains that predict mode of action

Boot, M., Commandeur, S., Subudhi, A. K., Bahira, M., Smith, T. C., Abdallah, A. M., van Gemert, M., Lelièvre, J., Ballell, L., Aldridge, B. B., Pain, A., Speer, A. & Bitter, W., Jul 2018, In : Antimicrobial Agents and Chemotherapy. 62, 7, e00083-18.

Research output: Contribution to JournalArticleAcademicpeer-review

Drug Discovery
Anti-Bacterial Agents
Mycobacterium marinum
Dermatoglyphics
Tuberculosis

Bacterial secretion chaperones: The mycobacterial type VII case

Phan, T. H. & Houben, E. N. G., 1 Sep 2018, In : FEMS Microbiology Letters. 365, 18, p. 1-8 8 p., fny197.

Research output: Contribution to JournalReview articleAcademicpeer-review

Open Access
Secretory Pathway
Protein Folding
Protein Transport
Mycobacterium
Cytosol

Prizes

AIMMS poster prize

M. Steenhuis (Recipient), Apr 2014

PrizeAcademic

Posters
Systems Analysis
Tolnaftate
Internship and Residency
Viperidae

NWO AIMMS STAR grant PhD

M. Steenhuis (Recipient), 2015

PrizeAcademic

Poster prize

M. Steenhuis (Recipient), Apr 2017

PrizeAcademic

Unilever research prize

M. Steenhuis (Recipient), 2015

PrizeAcademic

Press / Media

Interview Radio NPO1 Smaakmakers

W. Bitter

15/10/18

1 item of media coverage

Press/Media: Expert Comment

interview Volkskrant Tuberculose

W. Bitter

30/03/18

1 media contribution

Press/Media: Expert Comment