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Research Output 2006 2018

2018

Adenosine A2A receptors control glutamatergic synaptic plasticity in fast spiking interneurons of the prefrontal cortex

Kerkhofs, A., Canas, P. M., Timmerman, A. J., Heistek, T. S., Real, J. I., Xavier, C., Cunha, R. A., Mansvelder, H. D. & Ferreira, S. G., 20 Mar 2018, In : Frontiers in Pharmacology. 9, 20 March, p. 1-12 12 p., 133.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Adenosine A2A Receptors
Neuronal Plasticity
Interneurons
Prefrontal Cortex
Synapses
2017

Astrocyte lipid metabolism is critical for synapse development and function in vivo

van Deijk, A-L. F., Camargo, N., Timmerman, J., Heistek, T., Brouwers, J. F., Mogavero, F., Mansvelder, H. D., Smit, A. B. & Verheijen, M. H. G., Apr 2017, In : Glia. 65, 4, p. 670-682 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Lipid Metabolism
Astrocytes
Synapses
Sterol Regulatory Element Binding Proteins
Lipids

Hippocampal extracellular matrix alterations contribute to cognitive impairment associated with a chronic depressive-like state in rats

Riga, D., Kramvis, I., Koskinen, M. K., van Bokhoven, P., van der Harst, J. E., Heistek, T. S., Jaap Timmerman, A., van Nierop, P., van der Schors, R. C., Pieneman, A. W., de Weger, A., van Mourik, Y., Schoffelmeer, A. N. M., Mansvelder, H. D., Meredith, R. M., Hoogendijk, W. J. G., Smit, A. B. & Spijker, S., 20 Dec 2017, In : Science Translational Medicine. 9, 421

Research output: Contribution to JournalArticleAcademicpeer-review

Extracellular Matrix
Hippocampus
Long-Term Potentiation
Chondroitin ABC Lyase
Chondroitin Sulfate Proteoglycans
2014

Reducing hippocampal extracellular matrix reverses early memory deficits in a mouse model of Alzheimer's disease.

Vegh, M. J., Heldring, C. M., Kamphuis, W. W., Hijazi, S., Timmerman, A. J., Li, K. W., van Nierop, P., Mansvelder, H. D., Hol, E. M., Smit, A. B. & van Kesteren, R. E., 2014, In : Acta Neuropathologica Communications. 2, p. 76 76.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2013

α2-containing GABAA receptors expressed in hippocampal region CA3 control fast network oscillations

Heistek, T. S., Ruiperez Alonso, M., Timmerman, A. J., Brussaard, A. B. & Mansvelder, H. D., 2013, In : Journal of Physiology - London. 591, 4, p. 845-858 13 p., 4.

Research output: Contribution to JournalArticleAcademicpeer-review

Hippocampal CA3 Region
GABA-A Receptors
gamma-Aminobutyric Acid
2011

Fast network oscillations in vitro exhibit a slow decay of temporal auto-correlations

Poil, S. S., Jansen, R., van Aerde, K. I., Timmerman, J., Brussaard, A. B., Mansvelder, H. D. & Linkenkaer-Hansen, K., 2011, In : European Journal of Neuroscience. 34, 3, p. 394-403 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

GABA Modulators
Cholinergic Agonists
Brain
Carbachol
Brain Diseases

Novel Candidate Genes Associated with Hippocampal Oscillations

Jansen, R., Timmerman, J., Loos, M., Spijker, S., van Ooijen, A., Brussaard, A. B., Mansvelder, H. D., Smit, A. B., de Gunst, M. C. M. & Linkenkaer-Hansen, K., 2011, In : PLoS ONE. 6, 10, e26586.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
oscillation
Genes
Quantitative Trait Loci
Genome
genome
2010

GABAergic synapse properties may explain genetic variation in hippocampal network oscillations in mice

Heistek, T. S., Timmerman, A. J., Spijker, S., Brussaard, A. B. & Mansvelder, H. D., 2010, In : Frontiers in Cellular Neuroscience. 4, p. 18 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Synapses
Pyramidal Cells
Inbred Strains Mice
Aptitude
Carbachol
2009

Inbred mouse strains differ in multiple hippocampal activity traits

Jansen, R., Linkenkaer-Hansen, K., Heistek, T. S., Timmerman, A. J., Mansvelder, H. D., Brussaard, A. B., de Gunst, M. C. M. & van Ooyen, A., 2009, In : European Journal of Neuroscience. 30, 6, p. 1092-1100 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Inbred Strains Mice
Endophenotypes
Genes
Neurosciences
Synapses
2007

Reduced 5-HT1A- and GABAB receptor function in dorsal raphé neurons upon chronic fluoxetine treatment of socially stressed rats

Cornelisse, L. N., van der Harst, J. E., Lodder, J. C., Baarendse, P. J. J., Timmerman, A. J., Mansvelder, H. D., Spruijt, B. M. & Brussaard, A. B., 2007, In : Journal of Neurophysiology. 98, 1, p. 196-204

Research output: Contribution to JournalArticleAcademicpeer-review

Receptor, Serotonin, 5-HT1A
Fluoxetine
Serotonin
Neurons
2006

NMDA receptors trigger neurosecretion of 5-HT within dorsal raphé nucleus of the rat in the absence of action potential firing

de Kock, C. P. J., Cornelisse, L. N., Burnashev, N., Lodder, J. C., Timmerman, A. J., Couey, J. J., Mansvelder, H. D. & Brussaard, A. B., 2006, In : Journal of Physiology - London. 577, 3, p. 891-905 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Neurosecretion
N-Methyl-D-Aspartate Receptors
Action Potentials
Serotonin
Calcium

Oxytocin and estrogen promote rapid formation of functional GABA synapses in the adult supraoptic nucleus

Theodosis, D. T., Koksma, J. J., Trailin, A., Langle, S. L., Piet, R., Lodder, J. C., Timmerman, J., Mansvelder, H. D., Poulain, D. A., Oliet, S. H. R. & Brussaard, A. B., 2006, In : Molecular and Cellular Neuroscience. 31, 4, p. 785-794 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Supraoptic Nucleus
Oxytocin
Synapses
gamma-Aminobutyric Acid
Estrogens