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A.J.A. Groffen

dr. ir.

1993 …2019
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Synaptotagmin I Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Research Output 1993 2019

A Potential Role for the STXBP5-AS1 Gene in Adult ADHD Symptoms

The EAGLE-ADHD Consortium, 18 Jan 2019, In : Behavior Genetics. p. 1-16 16 p.

Research output: Contribution to Journal › Article › Academic › peer-review

Impulsive Behavior
Single Nucleotide Polymorphism
Meta-Analysis
signs and symptoms (animals and humans)
meta-analysis

SICT: automated detection and supervised inspection of fast Ca2+ transients

Mancini, R., van der Bijl, T., Bourgeois-Jaarsma, Q., Lasabuda, R. & Groffen, A. J., 19 Oct 2018, In : Scientific Reports. 8, p. 1-13 13 p., 15523.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access
Signal-To-Noise Ratio
Motion Pictures
Caffeine
Quality Control
Neurons

Transcription Factor 2I Regulates Neuronal Development via TRPC3 in 7q11.23 Disorder Models

Deurloo, M. H. S., Turlova, E., Chen, W. L., Lin, Y. W., Tam, E., Tassew, N. G., Wu, M., Huang, Y. C., Crawley, J. N., Monnier, P. P., Groffen, A. J. A., Sun, H. S., Osborne, L. R. & Feng, Z. P., 17 Aug 2018, In : Molecular Neurobiology. p. 1-13 13 p.

Research output: Contribution to Journal › Article › Academic › peer-review

Transcription Factors
Williams Syndrome
Calcium
Proteins
General Transcription Factors

Doc2B acts as a calcium sensor for vesicle priming requiring synaptotagmin-1, Munc13-2 and SNAREs

Houy, S., Groffen, A. J., Ziomkiewicz, I., Verhage, M., Pinheiro, P. S. & Sørensen, J. B., 23 Dec 2017, In : eLife. 6

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access
Synaptotagmin I
SNARE Proteins
Calcium
Sensors
Synaptotagmins

Tomosyn associates with secretory vesicles in neurons through its N- and C-terminal domains

Geerts, C. J., Mancini, R., Chen, N., Koopmans, F. T. W., Li, K. W., Smit, A. B., van Weering, J. R. T., Verhage, M. & Groffen, A. J. A., 2017, In : PLoS ONE. 12, 7, p. e0180912

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access
SNARE Proteins
secretory granules
Secretory Vesicles
Neurons
Synaptotagmin I