Barbara Zarzycka

20102019
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Fingerprint Dive into the research topics where Barbara Zarzycka is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
TNF Receptor-Associated Factor 6 Medicine & Life Sciences
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins Medicine & Life Sciences
Peptides Medicine & Life Sciences
Enzyme Activation Medicine & Life Sciences
Dipeptides Medicine & Life Sciences
G-Protein-Coupled Receptors Medicine & Life Sciences
Chemical activation Chemical Compounds
Esters Medicine & Life Sciences

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Research Output 2010 2019

A Thieno[2,3- d]pyrimidine Scaffold Is a Novel Negative Allosteric Modulator of the Dopamine D 2 Receptor

Fyfe, T. J., Zarzycka, B., Lim, H. D., Kellam, B., Mistry, S. N., Katrich, V., Scammells, P. J., Lane, J. R. & Capuano, B., 1 Oct 2019, In : Journal of Medicinal Chemistry. 62, 1, p. 174-206 33 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Dopamine
Ligands
Dopamine Receptors
Pharmacology
thieno(2,3-d)pyrimidine

Crystal structure of misoprostol bound to the labor inducer prostaglandin E 2 receptor

Audet, M., White, K. L., Breton, B., Zarzycka, B., Han, G. W., Lu, Y., Gati, C., Batyuk, A., Popov, P., Velasquez, J., Manahan, D., Hu, H., Weierstall, U., Liu, W., Shui, W., Katritch, V., Cherezov, V., Hanson, M. A. & Stevens, R. C., 1 Jan 2019, In : Nature Chemical Biology. 15, 1, p. 11-17 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Receptors, Prostaglandin E, EP2 Subtype
Misoprostol
Receptors, Prostaglandin E, EP3 Subtype
Induced Labor
Myometrium

Exploring Pairwise Chemical Crosslinking To Study Peptide–Receptor Interactions

Seidel, L., Zarzycka, B., Katritch, V. & Coin, I., 1 Mar 2019, In : ChemBioChem. 20, 5, p. 683-692 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Sulfhydryl Compounds
Crosslinking
Cysteine
Ligands
Corticotropin-Releasing Hormone Receptors

Harnessing ion-binding sites for GPCR pharmacology

Zarzycka, B., Zaidi, S. A., Roth, B. L. & Katritch, V., 1 Oct 2019, In : Pharmacological Reviews. 71, 4, p. 571-595 25 p.

Research output: Contribution to JournalArticleAcademicpeer-review

G-Protein-Coupled Receptors
Binding Sites
Pharmacology
Ions
Sodium

O-GlcNAc Engineering of GPCR Peptide-Agonists Improves Their Stability and in Vivo Activity

Levine, P. M., Balana, A. T., Sturchler, E., Koole, C., Noda, H., Zarzycka, B., Daley, E. J., Truong, T. T., Katritch, V., Gardella, T. J., Wootten, D., Sexton, P. M., McDonald, P. & Pratt, M. R., 11 Sep 2019, In : Journal of the American Chemical Society. 141, 36, p. 14210-14219 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Peptides
Glucagon-Like Peptide 1
Parathyroid Hormone
Glycosylation
Peptide Hormones