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Last mutation Ancillary Activities: Amsterdam(2017-05-19)

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Research Output 2004 2017

  • 87 Article
  • 3 Review article
  • 3 PhD Thesis - Research VU, graduation VU
  • 2 Chapter

1.15 - Structural Chemogenomics Databases to Navigate Protein–Ligand Interaction Space

Kanev, G. K., Kooistra, A. J., de Esch, I. J. P. & de Graaf, C. 2017 1.15 - Structural Chemogenomics Databases to Navigate Protein–Ligand Interaction Space. Comprehensive Medicinal Chemistry III ed. Elsvier, Vol. 1, p. 444-471

Research output: Scientific - peer-reviewChapter

3D-e-Chem-VM: Structural Cheminformatics Research Infrastructure in a Freely Available Virtual Machine

McGuire, R., Verhoeven, S., Vass, M., Vriend, G., De Esch, I. J. P., Lusher, S. J., Leurs, R., Ridder, L., Kooistra, A. J., Ritschel, T. & de Graaf, C. 27 Feb 2017 In : Journal of Chemical Information and Modeling. 57, 2, p. 115-121 7 p.

Research output: Scientific - peer-reviewArticle

Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators

Song, G. , Yang, D. , Wang, Y. , de Graaf, C. , Zhou, Q. , Jiang, S. , Liu, K. , Cai, X. , Dai, A. , Lin, G. , Liu, D. , Wu, F. , Wu, Y. , Zhao, S. , Ye, L. , Han, G. W. , Lau, J. , Wu, B. , Hanson, M. A. , Liu, Z. J. & 2 others Wang, M. W. & Stevens, R. C. 8 Jun 2017 In : Nature. 546, 7657, p. 312-315 4 p.

Research output: Scientific - peer-reviewArticle

Kinetics for Drug Discovery: an industry-driven effort to target drug residence time

Schuetz, D. A. , de Witte, W. E. A. , Wong, Y. C. , Knasmueller, B. , Richter, L. , Kokh, D. B. , Sadiq, S. K. , Bosma, R. , Nederpelt, I. , Heitman, L. H. , Segala, E. , Amaral, M. , Guo, D. , Andres, D. , Georgi, V. , Stoddart, L. A. , Hill, S. , Cooke, R. M. , de Graaf, C. , Leurs, R. & 6 others Frech, M., Wade, R. C., de Lange, E. C. M., IJzerman, A. P., Müller-Fahrnow, A. & Ecker, G. F. 1 Jun 2017 In : Drug Discovery Today. 22, 6, p. 896-911 16 p.

Research output: Scientific - peer-reviewReview article

Structural Analysis of Chemokine Receptor-Ligand Interactions

Arimont, M., Sun, S-L., Leurs, R., Smit, M., De Esch, I. J. P. & de Graaf, C. 22 Jun 2017 In : Journal of Medicinal Chemistry. 60, 12, p. 4735-4779 45 p.

Research output: Scientific - peer-reviewReview article