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Cormac Murphy gained his undergraduate degree in Zoology from Trinity College Dublin in 2014 with a thesis project in the field of Developmental Biology. He graduate with an MSc in Regenerative medicine from National university of Ireland Galway in 2015 where he worked on a project to model a rare form of familial retinitis pigmentosa using induced pluripotent stem(iPS) cells. He worked for fifteen months as a research scientist in Biotalentum, Hungary. In 2017 he stared his PhD as part of the Marie Skłodowska- Curie - International Training Network In3 project under the Supervision of Prof. Paul Jennings in the Molecular and Computation Toxicology division of the Vrije Universiteit, Amsterdam. His project focuses on the generation of a glomerular model from IPS cells and their application for nephrotoxicity testing.
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Comparison of human recombinant protein coatings and fibroblast-ECM to Matrigel for induced pluripotent stem cell culture and renal podocyte differentiation
Murphy, C., Naderlinger, E., Mater, A., Kluin, R. J. C. & Wilmes, A., 12 Jan 2023, In: ALTEX. 40, 1, p. 141-159 19 p.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Transcriptomic-based evaluation of trichloroethylene glutathione and cysteine conjugates demonstrate phenotype-dependent stress responses in a panel of human in vitro models
Capinha, L., Zhang, Y., Holzer, A. K., Ückert, A. K., Zana, M., Carta, G., Murphy, C., Baldovini, J., Mazidi, Z., Grillari, J., Dinnyes, A., van de Water, B., Leist, M., Commandeur, J. N. M. & Jennings, P., Feb 2023, In: Archives of Toxicology. 97, 2, p. 523-545 23 p.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals: A case study on paraquat
Nunes, C., Singh, P., Mazidi, Z., Murphy, C., Bourguignon, A., Wellens, S., Chandrasekaran, V., Ghosh, S., Zana, M., Pamies, D., Thomas, A., Verfaillie, C., Culot, M., Dinnyes, A., Hardy, B., Wilmes, A., Jennings, P., Grillari, R., Grillari, J., Zurich, M-G., & 1 others, Jun 2022, In: Toxicology in Vitro. 81, p. 1-16 16 p., 105333.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Generation and characterization of iPSC-derived renal proximal tubule-like cells with extended stability
Chandrasekaran, V., Carta, G., da Costa Pereira, D., Gupta, R., Murphy, C., Feifel, E., Kern, G., Lechner, J., Cavallo, A. L., Gupta, S., Caiment, F., Kleinjans, J. C. S., Gstraunthaler, G., Jennings, P. & Wilmes, A., Dec 2021, In: Scientific Reports. 11, p. 1-17 17 p., 11575.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
A protocol for one-step differentiation of human induced pluripotent stem cells into mature podocytes
Murphy, C., Feifel, E., Jennings, P., Gstraunthaler, G. & Wilmes, A., 2019, Cell-Based Assays Using iPSCs for Drug Development and Testing. Mandenius, C. F. & Ross, J. (eds.). Humana Press Inc., p. 93-99 7 p. (Methods in Molecular Biology; vol. 1994).Research output: Chapter in Book / Report / Conference proceeding › Chapter › Academic › peer-review