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D.J. Scholten

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20082015
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Fingerprint Dive into the research topics where D.J. Scholten is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 7 Similar Profiles
Chemokine Receptors Medicine & Life Sciences
Ligands Medicine & Life Sciences
G-Protein-Coupled Receptors Medicine & Life Sciences
CXCR3 Receptors Medicine & Life Sciences
Pharmacology Medicine & Life Sciences
Metabolites Chemical Compounds
Mass spectrometry Chemical Compounds
Mass Spectrometry Medicine & Life Sciences

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Research Output 2008 2015

  • 15 Article
  • 1 PhD Thesis - Research VU, graduation VU
Chemokine Receptors
Metabolites
Mass spectrometry
Mass Spectrometry
Ligands

Exploring the cxcr3 chemokine receptor with small-molecule antagonists and agonists

Wijtmans, M., Scholten, D., Mooij, W., Smit, M. J., De Esch, I. J. P., de Graaf, C. & Leurs, R., 2015, In : Topics in Medicinal Chemistry. 14, p. 119-185 68 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Chemokine Receptors
Ligands
Chemokines
Mutagenesis
CXCR Receptors

Metabolic profiling of ligands for the chemokine receptor CXCR3 by liquid chromatography-mass spectrometry coupled to bioaffinity assessment

Mladic, M., Scholten, D. J., Wijtmans, M., Falck, D., Leurs, R., Niessen, W. M. A., Smit, M. J. & Kool, J., Sep 2015, In : Analytical and Bioanalytical Chemistry. 407, 23, p. 7067-81 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Chemokine Receptors
Liquid chromatography
Liquid Chromatography
Mass spectrometry
Mass Spectrometry

Pharmacological characterization of [3H]VUF11211, a novel radiolabeled small-molecule inverse agonist for the chemokine receptor CXCR3

Scholten, D. J., Wijtmans, M., van Senten, J. R., Custers, H., Stunnenberg, A., de Esch, I. J. P., Smit, M. J. & Leurs, R., Apr 2015, In : Molecular Pharmacology. 87, 4, p. 639-48 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Chemokine Receptors
Pharmacology
Ligands
CXC Chemokines
5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-yl)-3-ethylpiperazin-1-yl)-N-ethylnicotinamide

Identification of Overlapping, but Differential Binding Sites for the High-affinity CXCR3 antagonists NBI-74330 and VUF11211

Scholten, D. J., Roumen, L., Wijtmans, M., Verkade-Vreeker, M. C., Custers, H., Lai, M., de Hooge, D., Canals, M., de Esch, I. J. P., Smit, M. J., de Graaf, C. & Leurs, R., 2014, In : Molecular Pharmacology. 85, 1, p. 116-126

Research output: Contribution to JournalArticleAcademicpeer-review

Binding Sites
Computer Simulation
CXCR Receptors
CXCR3 Receptors
Ligands

Prizes

Oral presentation award

D.J. Scholten (Recipient), 2011

PrizeAcademic