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  • 2012

    Common variants at 6q22 and 17q21 are associated with intracranial volume

    Arfan Ikram, M., Fornage, M., Smith, A. V., Seshadri, S., Schmidt, R., Debette, S., Vrooman, H. A., Sigurdsson, S., Ropele, S., Taal, H. R., Mook-Kanamori, D. O., Coker, L. H., Longstreth, J. W. T., Niessen, W. J., DeStefano, A. L., Beiser, A., Zijdenbos, A. P., Struchalin, M., Jack, C. R., Rivadeneira, F., & 43 othersUitterlinden, A. G., Knopman, D. S., Hartikainen, A-L., Pennell, C. E., Thiering, E., Steegers, E. A. P., Hakonarson, H., Heinrich, J., Palmer, L. J., Jarvelin, M-R., McCarthy, M. I., Grant, S. F. A., St Pourcain, B., Timpson, N. J., Smith, G. D., Sovio, U., van Beijsterveldt, C. E. M., Groen-Blokhuis, M. M., Hottenga, J. J., Middeldorp, C. M., Nivard, M. G., Willemsen, G., Boomsma, D. I., Nalls, M. A., Au, R., Hofman, A., Gudnason, H., van der Lugt, A., Harris, T. B., Meeks, W. M., Vernooij, M. W., van Buchem, M. A., Catellier, D., Jaddoe, V. W. V., Gudnason, V., Windham, B. G., Wolf, P. A., van Duijn, C. M., Mosley, T. H., Schmidt, H., Launer, L. J., Breteler, M. M. B. & DeCarli, C. S., 2012, In: Nature Genetics. 44, 5, p. 539-544

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Common Variants in the Type 2 Diabetes KCNQ1 Gene Are Associated with Impairments in Insulin Secretion During Hyperglycaemic Glucose Clamp

    van Vliet-Ostaptchouk, J. V., van Haeften, T. W., Landman, G. W. D., Reiling, E., Kleefstra, N., Bilo, H. J. G., Klungel, O. H., de Boer, A., van Diemen, C. C., Wijmenga, C., Boezen, H. M., Dekker, J. M., van 't Riet, E., Nijpels, G., Welschen, L. M. C., Zavrelová, H., Bruin, E. J., Elbers, C. C., Bauer, F., Onland-Moret, N. C., & 14 othersvan der Schouw, Y. T., Grobbee, D. E., Spijkerman, A. M. W., van der Aa, D. L., Bik-Simonis, A. M. C., Eekhoff, E. M. W., Diamant, M., Kramer, M. H. H., Boomsma, D. I., de Geus, E. J. C., Willemsen, G., Slagboom, P. E., Hofker, M. H. & Hart, L. M., 2012, In: PLoS ONE. 7, 3, e32148.

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  • De novo and inherited CNVs in MZ twin pairs selected for discordance and concordance on Attention Problems

    Ehli, E. A., Abdellaoui, A., Hu, Y., Hottenga, J. J., Kattenberg, V. M., van Beijsterveldt, C. E. M., Bartels, M., Althoff, R. R., Xiao, X., Scheet, P., de Geus, E. J. C., Hudziak, J. J., Boomsma, D. I. & Davies, G. E., 2012, In: European Journal of Human Genetics. 20, 10, p. 1037-1043

    Research output: Contribution to JournalArticleAcademicpeer-review

    Open Access
  • Detecting Specific Genotype by Environment Interactions Using Marginal Maximum Likelihood Estimation in the Classical Twin Design

    Molenaar, D., van der Sluis, S., Boomsma, D. I. & Dolan, C. V., 2012, In: Behavior Genetics. 42, 3, p. 483-499

    Research output: Contribution to JournalArticleAcademicpeer-review

    Open Access
  • Don't give up on GWAS

    Sullivan, P. F., Penninx, B. W. J. H., Boomsma, D. I. & Posthuma, D., 2012, In: Molecular Psychiatry. 17, 1, p. 2-3

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Effect of Shared Environmental Factors on Exercise Behavior from Age 7 to 12 Years

    Huppertz, C., Bartels, M., van Beijsterveldt, C. E. M., Boomsma, D. I., Hudziak, J. J. & de Geus, E. J. C., 2012, In: Medicine and Science in Sports and Exercise. 44, 10, p. 2025-2032

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Effects of Chorionicity and Zygosity on Triplet Birth Weight

    Ponsen-Lamb, D. J., Vink, J. M., Middeldorp, C. M., van Beijsterveldt, C. E. M., Haak, M., Overbeek, L. I. H. & Boomsma, D. I., 2012, In: Twin Research and Human Genetics. 15, 2, p. 149-157

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs

    Talens, R. P., Christensen, K., Putter, H., Willemsen, G., Christiansen, L., Kremer, D., Suchiman, H. E. D., Slagboom, P. E., Boomsma, D. I. & Heijmans, B. T., 2012, In: Aging Cell. 11, 4, p. 694-703

    Research output: Contribution to JournalArticleAcademicpeer-review

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  • Estimating the Genetic Variance of Major Depressive Disorder Due to All Single Nucleotide Polymorphisms

    Lubke, G. H., Hottenga, J. J., Walters, R., Laurin, C., de Geus, E. J. C., Willemsen, G., Smit, J. H., Middeldorp, C. M., Penninx, B. W. J. H., Vink, J. M. & Boomsma, D. I., 2012, In: Biological Psychiatry. 72, 8, p. 707-709

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Estimation of Subject-Specific Heritabilities From Intra-Individual Variation: iFACE

    Molenaar, P. C. M., Smit, D. J. A., Boomsma, D. I. & Nesselroade, J. R., 2012, In: Twin Research and Human Genetics. 15, 3, p. 393-400

    Research output: Contribution to JournalArticleAcademicpeer-review

  • FTO genotype is associated with phenotypic variability of body mass index

    Yang, J., Loos, R. J., Powell, J. E., Medland, S. E., Speliotes, E. K., Chasman, D. I., Rose, L. M., Thorleifsson, G., Steinthorsdottir, V., Mägi, R., Waite, L., Smith, A. V., Yerges-Armstrong, L. M., Monda, K. L., Hadley, D., Mahajan, A., Li, G., Kapur, K., Vitart, V., Huffman, J. E., & 151 othersWang, S. R., Palmer, C., Esko, T., Fischer, K., Zhao, J. H., Demirkan, A., Isaacs, A., Feitosa, M. F., Luan, J., Heard-Costa, N. L., White, C., Jackson, A. U., Preuss, M., Ziegler, A., Eriksson, J., Kutalik, Z., Frau, F., Nolte, I. M., van Vliet-Ostaptchouk, J. V., Hottenga, J. J., Jacobs, K. B., Verweij, N., Goel, A., Medina-Gomez, C., Estrada, K., Bragg-Gresham, J. L., Sanna, S., Sidore, C., Tyrer, J., Teumer, A., Prokopenko, I., Mangino, M., Lindgren, C. M., Assimes, T. L., Shuldiner, A. R., Hui, J., Beilby, J. P., McArdle, W. L., Hall, P., Haritunians, T., Zgaga, L., Kolcic, I., Polasek, O., Zemunik, T., Oostra, B. A., Junttila, M. J., Grönberg, H., Schreiber, S., Peters, A., Hicks, A. A., Stephens, J., Foad, N. S., Laitinen, J., Pouta, A., Kaakinen, M., Willemsen, G., Vink, J. M., Wild, S. H., Navis, G., Asselbergs, F. W., Homuth, G., John, U., Iribarren, C., Harris, T., Launer, L. J., Gudnason, V., O'Connell, J. R., Boerwinkle, E., Cadby, G., Palmer, L. J., James, A. L., Musk, A. W., Ingelsson, E., Psaty, B. M., Beckmann, J. S., Waeber, G., Vollenweider, P., Hayward, C., Wright, A. F., Rudan, I., Groop, L. C., Metspalu, A., Thee Khaw, K., van Duijn, C. M., Borecki, I. B., Province, M. A., Wareham, N. J., Tardif, J. C., Huikuri, H. V., Cupples, L. A., Atwood, L. D., Fox, C. S., Boehnke, M., Collins, F. S., Mohlke, K. L., Erdmann, J., Schunkert, H., Hengstenberg, C., Stark, K., Lorentzon, M., Ohlsson, C., Cusi, D., Staessen, J. A., van der Klauw, M. M., Pramstaller, P. P., Kathiresan, S., Jolley, D. J., Ripatti, S., Jarvelin, M-R., de Geus, E. J. C., Boomsma, D. I., Penninx, B. W. J. H., Wilson, J. F., Campbell, H., Chanock, S. J., van der Harst, P., Hamsten, A., Watkins, H., Hofman, A., Witteman, J. C., Zillikens, M. C., Uitterlinden, A. G., Rivadeneira, F., Kiemeney, L. A., Vermeulen, S. H., Abecasis, G. R., Schlessinger, D., Schipf, S., Stumvoll, M., Tönjes, A., Spector, T. D., North, K. E., Lettre, G., McCarthy, M. I., Berndt, S. I., Heath, A. C., Madden, P. A. F., Nyholt, DR., Montgomery, G. W., Martin, N. G., McKnight, B., Strachan, D. P., Hill, W. G., Snieder, H., Ridker, P. M., Thorsteinsdottir, U., Stefansson, K., Frayling, T. M., Hirschhorn, J. N., Goddard, M. E. & Visscher, P. M., 2012, In: Nature. 490, 7419, p. 267-272

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Gene–environment interaction in teacher-rated internalizing and externalizing problem behavior in 7- to 12-year-old twins

    Ponsen-Lamb, D. J., Middeldorp, C. M., van Beijsterveldt, C. E. M. & Boomsma, D. I., 2012, In: Journal of Child Psychology and Psychiatry. 53, 8, p. 818-825

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Genetic and Environmental Contributions to Self-Reported Thoughts of Self-Harm and Suicide

    Althoff, R. R., Hudziak, J. J., Willemsen, G., Hudziak, V., Bartels, M. & Boomsma, D. I., 2012, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 159B, 1, p. 120-127

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Genetic and Environmental Influences on Individual Differences in Sedentary Behavior During Adolescence

    van der Aa, N., Bartels, M., te Velde, S. J., Boomsma, D. I., de Geus, E. J. C. & Brug, J., 2012, In: Archives of Pediatrics and Adolescent Medicine. 166, 6, p. 509-514

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Genetic influences on thinning of the cerebral cortex during development

    van Soelen, I. L. C., Brouwer, R. M., van Baal, G. C. M., Schnack, H. G., Peper, J. S., Collins, D. L., Evans, A. C., Kahn, R. S., Boomsma, D. I. & Hulshoff Pol, H. E., 2012, In: NeuroImage. 59, 4, p. 3871-3880

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM

    Amin, N., Byrne, E., Johnson, J., Chenevix-Trench, G., Walter, S., Nolte, I. M., Vink, J. M., Rawal, R., Mangino, M., Teumer, A., Keers, J. C., Verwoert, G., Baumeister, S., Biffar, R., Petersmann, A., Dahmen, N., Doering, A., Isaacs, A., Broer, L., Wray, N. R., & 31 othersMontgomery, G. W., Levy, D., Psaty, B. M., Gudnason, V., Chakravarti, A., Sulem, P., Gudbjartsson, D. F., Kiemeney, L. A., Thorsteinsdottir, U., Stefansson, K., van Rooij, F. J. A., Aulchenko, Y. S., Rivadeneira, F., Hofman, A., Uitterlinden, A. G., Hammond, C. J., Shin, S. Y., Arfan Ikram, M., Witteman, J. C. M., Janssens, A. C. J. W., Snieder, H., Tiemeier, H., Wolfenbuttel, B. H. R., Oostra, B. A., Heath, A. C., Wichmann, E., Spector, T. D., Grabe, H. J., Boomsma, D. I., Martin, N. G. & van Duijn, C. M., 2012, In: Molecular Psychiatry. 17, 11, p. 1116-1129

    Research output: Contribution to JournalArticleAcademicpeer-review

    Open Access
  • Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women

    Fox, C. S., Liu, Y., White, C. C., Feitosa, M., Smith, A. V., Heard-Costa, N., Lohman, K., Hottenga, J. J., de Geus, E. J. C., Willemsen, G., Boomsma, D. I., Johnson, A. D., Foster, M. C., Greenawalt, D. M., Griffin, P., Ding, J., Newman, A. B., Tylavsky, F., Miljkovic, I., Kritchevsky, S. B., & 9 othersLauner, L., Garcia, M., Eiriksdottir, G., Posthuma, D., Carr, J. J., Gudnason, V., Harris, T. B., Cupples, L. A. & Borecki, I. B., 2012, In: PLoS Genetics. 8, 5, p. e1002695 e1002695.

    Research output: Contribution to JournalArticleAcademicpeer-review

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  • Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned

    Wray, N. R., Pergadia, M. L., Blackwood, D. H., Penninx, B. W. J. H., Gordon, S. D., Nyholt, DR., Ripke, S., MacIntyre, D. J., McGhee, K. A., Maclean, A. W., Smit, J. H., Hottenga, J. J., Willemsen, G., Middeldorp, C. M., de Geus, E. J. C., Lewis, C. M., McGuffin, P., Hickie, I. B., van den Oord, E. J. C. G., Liu, J. Z., & 12 othersMacgregor, S., McEvoy, B. P., Byrne, E. M., Medland, S. E., Statham, D. J., Henders, A. K., Heath, A. C., Montgomery, G. W., Martin, N. G., Boomsma, D. I., Madden, P. A. F. & Sullivan, P. F., 2012, In: Molecular Psychiatry. 17, 1, p. 36-48

    Research output: Contribution to JournalArticleAcademicpeer-review

    Open Access
  • Genome-Wide Association Uncovers Shared Genetic Effects Among Personality Traits and Mood States

    Luciano, M., Huffman, J. E., Arias-Vasquez, A., Vinkhuyzen, A. A. E., Middeldorp, C. M., Giegling, I., Payton, A., Davies, G. E., Zgaga, L., Janzing, J. G., Ke, X. Y., Galesloot, T., Hartmann, A. M., Ollier, W., Tenesa, A., Hayward, C., Verhagen, M., Montgomery, G. W., Hottenga, J. J., Konte, B., & 24 othersStarr, J. M., Vitart, V., Vos, P. E., Madden, P. A. F., Willemsen, G., Konnerth, H., Horan, M. A., Porteous, D. J., Campbell, H., Vermeulen, S. H., Heath, A. C., Wright, A., Polasek, O., Kovacevic, S. B., Hastie, N., Franke, B., Boomsma, D. I., Martin, N. G., Rujescu, D., Wilson, J. F., Buitelaar, J., Pendleton, N., Rudan, I. & Deary, I. J., 2012, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 159B, 6, p. 684-695

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Genome-wide meta-analysis of common variant differences between men and women

    Boraska, V., Jeroncic, A., Colonna, V., Southam, L., Nyholt, DR., Rayner, N. W., Perry, J. R. B., Toniolo, D., Albrecht, E., Ang, W., Bandinelli, S., Barbalic, M., Barroso, I., Beckmann, J. S., Biffar, R., Boomsma, D. I., Campbell, H., Corre, T., Erdmann, J., Esko, T., & 107 othersFischer, K., Franceschini, N., Frayling, T. M., Girotto, G., Gonzalez, J. R., Harris, T. B., Heath, A. C., Heid, I. M., Hoffmann, W., Hofman, A., Horikoshi, M., Zhao, J. H., Jackson, A. U., Hottenga, J. J., Jula, A., Kähönen, M., Khaw, K. T., Kiemeney, L. A., Klopp, N., Kutalik, Z., Lagou, V., Launer, L. J., Lehtimäki, T., Lemire, M., Lokki, M. L., Loley, C., Luan, J. A., Mangino, M., Mateo Leach, I., Medland, S. E., Mihailov, E., Montgomery, G. W., Navis, G., Newnham, J., Nieminen, M. S., Palotie, A., Panoutsopoulou, K., Peters, A., Pirastu, N., Polasek, O., Rehnström, K., Ripatti, S., Ritchie, G. R. S., Rivadeneira, F., Robino, A., Samani, N. J., Shin, S. Y., Sinisalo, J., Smit, J. H., Soranzo, N., Stolk, L., Swinkels, D. W., Tanaka, T., Teumer, A., Tönjes, A., Traglia, M., Tuomilehto, J., Valsesia, A., van Gilst, W. H., van Meurs, J. B. J., Vernon Smith, A., Viikari, J., Vink, J. M., Waeber, G., Warrington, N. M., Widen, E., Willemsen, G., Wright, A. F., Zanke, B. W., Zgaga, L., Boehnke, M., Pio d'Adamo, A., de Geus, E. J. C., Demerath, E. W., den Heijer, M., Eriksson, J. G., Ferrucci, L., Gieger, C., Gudnason, V., Hayward, C., Hengstenberg, C., Hudson, T. J., Järvelin, M. J., Kogevinas, M., Loos, R. J. F., Martin, N. G., Metspalu, A., Pennell, C. E., Penninx, B. W. J. H., Perola, M., Raitakari, O., Salomaa, V., Schreiber, S., Schunkert, H., Spector, T. D., Stumvoll, M., Uitterlinden, A. G., Ulivi, S., van der Harst, P., Vollenweider, P., Völzke, H., Wareham, N. J., Wichmann, H. E., Wilson, J. F., Rudan, I., Xue, Y. & Zeggini, E., 2012, In: Human Molecular Genetics. 21, 21, p. 4805-4815

    Research output: Contribution to JournalArticleAcademicpeer-review

    Open Access
  • Glucocorticoid receptor gene polymorphisms are associated with reduced first-phase glucose-stimulated insulin secretion and disposition index in women, but not in men

    van Raalte, D. H., van Leeuwen, N., Bik-Simonis, A. M. C., Nijpels, G., van Haeften, T. W., Schafer, S. A., Boomsma, D. I., Kramer, M. H. H., Heine, R. J., Maassen, J. A., Staiger, H., Machicao, F., Häring, H. U., Slagboom, P. E., Willemsen, G., de Geus, E. J. C., Dekker, J. M., Fritsche, A., Eekhoff, E. M. W., Diamant, M., & 1 othersHart, L. M., 2012, In: Diabetic Medicine. 29, 8, p. e211-e216

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Heritability estimates of body size in fetal life and early childhood

    Mook-Kanamori, D. O., van Beijsterveldt, C. E. M., Steegers, E. A., Aulchenko, Y. S., Raat, H., Hofman, A., Eilers, P. H. C., Boomsma, D. I. & Jaddoe, V. W. V., 2012, In: PLoS ONE. 7, 7, e39901.

    Research output: Contribution to JournalArticleAcademicpeer-review

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  • Heritability of body mass index in pre-adolescence, young adulthood and late adulthood

    Nan, C., Guo, B., Warner, C., Fowler, T., Barrett, T., Boomsma, D. I., Nelson, T., Whitfield, K., Beunen, G., Thomis, M., Maes, H. H., Derom, C. A., Ordoñana, J. R., Deeks, J. & Zeegers, M. P. A., 2012, In: European Journal of Epidemiology. 27, 4, p. 247-253

    Research output: Contribution to JournalArticleAcademicpeer-review

  • How to deal with the early GWAS data when imputing and combining different arrays is necessary

    Uh, H. W., Deelen, J., Beekman, M., Helmer, Q., Rivadeneira, F., Boomsma, D. I., Hofman, A., Uitterlinden, A. G., Slagboom, P. E., Böhringer, S. & Houwing-Duistermaat, J. J., 2012, In: European Journal of Human Genetics. 20, 5, p. 573-576

    Research output: Contribution to JournalArticleAcademicpeer-review

    Open Access
  • How to kickstart a national biobanking infrastructure – experiences and prospects of BBMRI-NL

    Brandsma, M., Baas, F., Bakker, P. I. W., Beem, E. P., Boomsma, D. I., Bovenberg, J., Bueno-de Mesquita, B., van Duijn, C. M., Kiemeney, L. A., Klungel, O., de Leeuw, P. W., van Leeuwen, F., Ridder-Numan, J., Stolk, R. P., Slagboom, P. E., Swertz, M., Wijmenga, C. & van Ommen, G. J. B., 2012, In: Nordic Psychology. 21, 2, p. 143-148

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Identification of common variants associated with human hippocampal and intracranial volumes

    Stein, J. L., Medland, S. E., Arias-Vasquez, A., Hibar, D. P., Senstad, R. E., Winkler, A. M., Toro, R., Appel, K., Bartecek, R., Bergmann, O., Hottenga, J. J., Boomsma, D. I., Montgomery, G. W., de Geus, E. J. C., Hulshoff Pol, H. E., Kahn, R. S., Penninx, B. W. J. H., Sämann, P. G., Saykin, A. J., Schumann, G., & 7 othersSmoller, J. W., Wardlaw, J. M., Weale, M. E., Martin, N. G., Franke, B., Wright, M. J. & Thompson, P. M., 2012, In: Nature Genetics. 44, 5, p. 552-561

    Research output: Contribution to JournalArticleAcademicpeer-review

    Open Access
  • Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

    Hartz, S. M., Short, S. E., Saccone, N. L., Culverhouse, R., Chen, L., Schwantes-An, T. H., Coon, H., Han, Y., Stephens, S. H., Sun, J., Chen, X., Ducci, F., Dueker, N., Franceschini, N., Frank, J., Geller, F., Gubjartsson, D., Hansel, N. N., Jiang, C., Keskitalo-Vuokko, K., & 132 othersLiu, Z., Lyytikäinen, L. P., Michel, M., Rawal, R., Rosenberger, A., Scheet, P., Shaffer, J. R., Teumer, A., Thompson, J. R., Vink, J. M., Vogelzangs, N., Wenzlaff, A. S., Wheeler, W., Xiao, X., Yang, B. Z., Aggen, S. H., Balmforth, A. J., Baumeister, S. E., Beaty, T., Bennett, S., Bergen, A. W., Boyd, H. A., Broms, U., Campbell, H., Chatterjee, N., Chen, J., Cheng, Y. C., Cichon, S., Couper, D., Cucca, F., Dick, D. M., Foroud, T., Furberg, H., Giegling, I., Gu, F., Hall, A. S., Hällfors, J., Han, S., Hartmann, A. M., Hayward, C., Heikkilä, K., Hewitt, J. K., Hottenga, J. J., Jensen, M. K., Jousilahti, P., Kaakinen, M., Kittner, S. J., Konte, B., Korhonen, T., Landi, M. T., Laatikainen, T., Leppert, M., Levy, S. M., Mathias, R. A., McNeil, D. W., Medland, S. E., Montgomery, G. W., Muley, T., Murray, T., Nauck, M., North, K., Pergadia, M. L., Polasek, O., Ramos, E. M., Ripatti, S., Risch, A., Ruczinski, I., Rudan, I., Salomaa, V., Schlessinger, D., Styrkársdóttir, U., Terracciano, A., Uda, M., Willemsen, G., Wu, X., Abecasis, G. R., Barnes, K., Bickeböller, H., Boerwinkle, E., Boomsma, D. I., Caporaso, N., Duan, J., Edenberg, H. J., Francks, C., Gejman, P. V., Gelernter, J., Grabe, H. J., Hops, H., Jarvelin, M. R., Viikari, J., Kähönen, M., Kendler, K. S., Lehtimäki, T., Levinson, D. F., Marazita, M. L., Marchini, J., Melbye, M., Mitchell, B. D., Murray, J. C., Nöthen, M. M., Penninx, B. W. J. H., Raitakari, O., Rietschel, M., Rujescu, D., Samani, N. J., Sanders, A. R., Schwartz, A. G., Shete, S., Shi, J., Spitz, M., Stefansson, K., Swan, G. E., Thorgeirsson, T. E., Völzke, H., Wei, Q., Wichmann, H. E., Amos, C. I., Breslau, N., Cannon, D. S., Ehringer, M., Grucza, R. A., Hatsukami, D., Heath, A. C., Johnson, E. O., Kaprio, J., Madden, P., Martin, N. G., Stevens, V. L., Stitzel, J. A., Weiss, R. B., Kraft, P. & Bierut, L. J., 2012, In: Archives of General Psychiatry. 69, 8, p. 854-860

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Individual Differences in EEG Spectral Power Reflect Genetic Variance in Gray and White Matter Volumes

    Smit, D. J. A., Boomsma, D. I., Schnack, H. G., Hulshoff Pol, H. E. & de Geus, E. J. C., 2012, In: Twin Research and Human Genetics. 15, 3, p. 384-392

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

    Scott, R. A., Lagou, V., Welch, R. P., Wheeler, E., Montasser, M. E., Luan, J., Mägi, R., Strawbridge, R. J., Rehnberg, E., Gustafsson, S., Kanoni, S., Rasmussen-Torvik, L. J., Yengo, L., Lecoeur, C., Shungin, D., Hottenga, J. J., Willemsen, G., de Geus, E. J. C., Penninx, B. W. J. H., van Duijn, C. M., & 17 othersBoomsma, D. I., Mohlke, K. L., Balkau, B., Froguel, P., Pouta, A., Jarvelin, M-R., Wareham, N. J., Bouatia-Naji, N., McCarthy, M. I., Franks, P. W., Meigs, J. B., Teslovich, T. M., Florez, J. C., Langenberg, C., Ingelsson, E., Prokopenko, I. & Barroso, I., 2012, In: Nature Genetics. 44, 9, p. 991-1005

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  • Loci Affecting Gamma-Glutamyl Transferase in Adults and Adolescents Show Age X SNP interaction and Cardiometabolic Disease Associations

    Middelberg, R. P. S., Benyamin, B., de Moor, M. H. M., Warrington, N. M., Gordon, S., Henders, A. K., Medland, S. E., Nyholt, DR., de Geus, E. J. C., Hottenga, J. J., Willemsen, G., Beilin, L. J., Mori, T. A., Wright, M. J., Heath, A. C., Madden, P. A. F., Boomsma, D. I., Pennell, C. E., Montgomery, G. W., Martin, N. G., & 1 othersWhitfield, J. B., 2012, In: Human Molecular Genetics. 21, 2, p. 446-455

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Longevity Candidate Genes and Their Association With Personality Traits in the Elderly

    Luciano, M., Lopez, L. M., de Moor, M. H. M., Harris, S. E., Davies, G., Nutile, T., Krueger, R. F., Esko, T., Schlessinger, D., Toshiko, T., Derringer, J., Realo, A., Hansell, N. K., Pergadia, M. L., Pesonen, A-K., Sanna, S., Terracciano, A., Madden, P. A. F., Penninx, B. W. J. H., Spinhoven, P. D., & 18 othersHartman, C. A., Oostra, B. A., Janssens, A. C. J. W., Eriksson, J. G., Starr, J. M., Cannas, A., Ferrucci, L., Metspalu, A., Wright, M. J., Heath, A. C., van Duijn, C. M., Bierut, L. J., Raikkonen, K., Martin, N. G., Ciullo, M., Rujescu, D., Boomsma, D. I. & Deary, I. J., 2012, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 159B, 2, p. 192-200

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Magnetoencephalography in Twins Reveals a Strong Genetic Determination of the Peak Frequency of Visually Induced Gamma-Band Synchronization

    van Pelt, S., Boomsma, D. I. & Fries, P., 2012, In: The Journal of Neuroscience. 32, 10, p. 3388-3392

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  • Maternal prenatal smoking and offspring emotional problems: No moderating effect of maternal or child 5-HTTLPR genotype

    Geels, L. M., Groen-Blokhuis, M. M., van Beijsterveldt, C. E. M., Vink, J. M., Middeldorp, C. M., Bartels, M., Nelson, K. A., Huizenga, P. E., Davies, G. E. & Boomsma, D. I., 2012, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 159B, 8, p. 1009-1012

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

    Stolk, L., Perry, J. R. B., Chasman, D. I., He, C., Mangino, M., Sulem, P., Barbalic, M., Broer, L., Byrne, E. M., Ernst, F., Esko, T., Franceschini, N., Gudbjartsson, D. F., Hottenga, J. J., Kraft, P., McArdle, P. F., Porcu, E., Shin, S. Y., Smith, A. V., van Wingerden, S., & 34 othersZhai, G., Zhuang, W. V., Albrecht, E., Alizadeh, BZ., Aspelund, T., de Geus, E. J. C., Vink, J. M., Willemsen, G., Boomsma, D. I., Crisponi, L., Demerath, E. W., Gudnason, V., Harris, T. B., Hu, F. B., Hunter, D. J., Launer, L. J., Metspalu, A., Montgomery, G. W., Oostra, B. A., Ridker, P. M., Sanna, S., Schlessinger, D., Spector, T. D., Stefansson, K., Streeten, E. A., Thorsteinsdottir, U., Uda, M., Uitterlinden, A. G., van Duijn, C. M., Völzke, H., Murray, A., Murabito, J. M., Visser, J. A. & Lunetta, K. L., 2012, In: Nature Genetics. 44, 3, p. 260-268

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  • Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes

    Webb, B. T., Guo, A. Y., Maher, B. S., Zhao, Z., van den Oord, E. J., Kendler, K. S., Riley, B. P., Gillespie, N. A., Prescott, C. A., Middeldorp, C. M., Willemsen, G., de Geus, E. J. C., Hottenga, J. J., Boomsma, D. I., Slagboom, P. E., Wray, N. R., Montgomery, G. W., Martin, N. G., Wright, M. J., Heath, A. C., & 15 othersMadden, P. A. F., Gelernter, J., Knowles, J. A., Hamilton, S. P., Weissman, M. M., Fyer, A. J., Huezo-Diaz, P., McGuffin, P., Farmer, A., Craig, I. W., Lewis, C., Sham, P., Crowe, R. R., Flint, J. & Hettema, J. M., 2012, In: European Journal of Human Genetics. 20, 10, p. 1078-1084

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  • Meta-analysis of genome-wide association studies for personality

    de Moor, M. H. M., Costa, P. T., Terracciano, A., Krueger, R. F., de Geus, E. J. C., Toshiko, T., Penninx, B. W. J. H., Esko, T., Madden, P. A. F., Derringer, J., Amin, N., Willemsen, G., Hottenga, J. J., Distel, M. A., Uda, M., Sanna, S., Spinhoven, P., Hartman, C. A., Sullivan, P. F., Realo, A., & 37 othersAllik, J., Heath, A. C., Pergadia, M. L., Agrawal, A., Lin, P., Grucza, R. A., Nutile, T., Ciullo, M., Rujescu, D., Giegling, I., Konte, B., Widen, E., Cousminer, D. L., Eriksson, J. G., Palotie, A., Peltonen, L., Luciano, M., Tenesa, A., Davies, G., Lopez, L. M., Hansell, N. K., Medland, S. E., Ferrucci, L., Schlessinger, D., Montgomery, G. W., Wright, M. J., Aulchenko, Y. S., Janssens, A. C. J. W., Oostra, B. A., Metspalu, A., Abecasis, G. R., Deary, I. J., Räikkönen, K., Bierut, L. J., Martin, N. G., van Duijn, C. M. & Boomsma, D. I., 2012, In: Molecular Psychiatry. 17, 3, p. 337-349

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  • Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis

    Paternoster, L., Standl, M., Chen, C. M., Ramasamy, A., Bønnelykke, K., Duijts, L., Ferreira, M. A., Couto Alves, A., Thyssen, J. P., Albrecht, E., Baurecht, H., Feenstra, B., Sleiman, P. M. A., Hysi, P., Warrington, N. M., Curjuric, I., Myhre, R., Curtin, J. A., Groen-Blokhuis, M. M., Kerkhof, M., & 71 othersSääf, A., Franke, A., Ellinghaus, D., Fölster-Holst, R., Dermitzakis, E., Montgomery, S. B., Prokisch, H., Heim, K., Hartikainen, A-L., Pouta, A., Pekkanen, J., Blakemore, A. I. F., Buxton, J. L., Kaakinen, M., Duffy, DL., Madden, P. A. F., Heath, A. C., Montgomery, G. W., Thompson, P. J., Matheson, M. C., Le Souëf, P., St Pourcain, B., Davey Smith, G., Henderson, J., Kemp, J. P., Timpson, N. J., Deloukas, P., Ring, S. M., Wichmann, H-E., Müller-Nurasyid, M., Novak, N., Klopp, N., Rodríguez, E., McArdle, W., Linneberg, A., Menné, T., Nohr, E. A., Hofman, A., Uitterlinden, A. G., van Duijn, C. M., Rivadeneira, F., de Jongste, J. C., van der Valk, R. J. P., Wjst, M., Jogi, R., Geller, F., Boyd, H. A., Murray, J. C., Kim, C., Mentch, F., March, M., Mangino, M., Spector, T. D., Bataille, V., Pennell, C. E., Holt, P. G., Sly, P., Tiesler, C. M. T., Hottenga, J. J., Boomsma, D. I., Hakonarson, H., Melbye, M., Ljarvis, D., Jaddoe, V. W. V., Gieger, C., Strachan, D. P., Martin, N. G., Jarvelin, M-R., Heinrich, J., Evans, D. M. & Weidinger, S., 2012, In: Nature Genetics. 44, 2, p. 187-192

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  • Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder

    Lee, P. H., Perlis, R. H., Jung, J. Y., Byrne, E. M., Rueckert, E., Siburian, R., Haddad, S., Mayerfeld, C. E., Heath, A. C., Pergadia, M. L., Madden, P. A. F., Boomsma, D. I., Penninx, B. W. J. H., Sklar, P., Martin, N. G., Wray, N. R., Purcell, S. M. & Smoller, J. W., 2012, In: Translational Psychiatry. 2, p. e184 e184.

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  • Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

    Dastani, Z., Hivert, M. F., Timpson, N. J., Perry, J. R., Yuan, X., Scott, R. A., Henneman, P., Heid, I. M., Kizer, J. R., Lyytikäinen, L. P., Fuchsberger, C., Tanaka, T., Morris, A. P., Small, K., Isaacs, A., Beekman, M., Coassin, S., Lohman, K., Qi, L., Kanoni, S., & 101 othersPankow, J. S., Uh, H. W., Wu, Y., Bidulescu, A., Rasmussen-Torvik, L. J., Greenwood, C. M., Ladouceur, M., Grimsby, J., Manning, A. K., Liu, C. T., Kooner, J., Mooser, V. E., Vollenweider, P., Kapur, K. A., Chambers, J., Wareham, N. J., Langenberg, C., Frants, R., Willems van Dijk, K., Oostra, B. A., Willems, S. M., Lamina, C., Winkler, T. W., Psaty, B. M., Tracy, R. P., Brody, J., Chen, I., Viikari, J., Kähönen, M., Pramstaller, P. P., Evans, D. M., St Pourcain, B., Sattar, N., Wood, A. R., Bandinelli, S., Carlson, O. D., Egan, J. M., Böhringer, S., van Heemst, D., Kedenko, L., Kristiansson, K., Nuotio, M. L., Loo, B. M., Harris, T., Garcia, M., Kanaya, A., Haun, M., Klopp, N., Wichmann, H. E., Deloukas, P., Katsareli, E., Couper, D. J., Duncan, B. B., Kloppenburg, M., Adair, L. S., Borja, J. B., Hottenga, J. J., de Geus, E. J. C., Willemsen, G., Boomsma, D. I., Wilson, J. G., Musani, G., Guo, X., Johnson, T., Semple, R., Teslovich, T. M., Allison, M. A., Redline, S., Buxbaum, S. G., Mohlke, K. L., Meulenbelt, I., Ballantyne, C. M., Dedoussis, G. V., Hu, F. B., Liu, Y., Paulweber, B., Spector, T. D., Slagboom, P. E., Ferrucci, L., Jula, A., Perola, M., Raitakari, O., Florez, J. C., Salomaa, V., Eriksson, J. G., Frayling, T. M., Hicks, A. A., Lehtimäki, T., Smith, G. D., Siscovick, D. S., Kronenberg, F., van Duijn, C. M., Loos, R. J., Waterworth, D., Meigs, J. B., Dupuis, J., Richards, J. B., Posthuma, D., Penninx, B. W. J. H., Vogelzangs, N. & Kathiresan, S., 2012, In: PLoS Genetics. 8, 3, p. e1002607 e1002607.

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  • Overlapping and Segregating Structural Brain Abnormalities in Twins With Schizophrenia or Bipolar Disorder

    Hulshoff Pol, H. E., van Baal, G. C. M., Schnack, H. G., Brans, R. G. H., van der Schot, A. C., Brouwer, R. M., van Haren, N. E. M., Lepage, C., Collins, D. L., Evans, A. C., Boomsma, D. I., Nolen, W. & Kahn, R. S., 2012, In: Archives of General Psychiatry. 69, 4, p. 349-359

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Regular exercise, subjective wellbeing, and internalizing problems in adolescence: causality or genetic pleiotropy?

    Bartels, M., de Moor, M. H. M., van der Aa, N., Boomsma, D. I. & de Geus, E. J. C., 2012, In: Frontiers in Genetics. 3, p. 1-12 4.

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  • Seventy-five genetic loci influencing the human red blood cell

    van der Harst, P., Zhang, W., Mateo Leach, I., Rendon, A., Verweij, N., Sehmi, J., Paul, D. S., Elling, U., Allayee, H., Li, X., Radhakrishnan, A., Tan, S. T., Voss, K., Weichenberger, C. X., Albers, C. A., Al-Hussani, A., Asselbergs, F. W., Ciullo, M., Danjou, F., Dina, C., & 175 othersEsko, T., Evans, D. M., Franke, L., Gögele, M., Hartiala, J., Hersch, M., Holm, H., Hottenga, J. J., Kanoni, S., Kleber, M. E., Lagou, V., Langenberg, C., Lopez, L. M., Lyytikäinen, L. P., Melander, O., Murgia, F., Nolte, I. M., O'Reilly, P. F., Padmanabhan, S., Parsa, A., Pirastu, N., Porcu, E., Portas, L., Prokopenko, I., Ried, J. S., Shin, S. Y., Tang, C. S., Teumer, A., Traglia, M., Ulivi, S., Westra, H. J., Yang, J., Zhao, J. H., Anni, F., Abdellaoui, A., Attwood, A., Balkau, B., Bandinelli, S., Bastardot, F., Benyamin, B., Boehm, B. O., Cookson, W. O., Das, D., de Bakker, P. I., de Boer, R. A., de Geus, E. J. C., de Moor, M. H. M., Dimitriou, M., Domingues, F. S., Döring, A., Engström, G., Eyjolfsson, G. I., Ferrucci, L., Fischer, K., Galanello, R., Garner, S. F., Genser, B., Gibson, Q. D., Girotto, G., Gudbjartsson, D. F., Harris, S. E., Hartikainen, A. L., Hastie, C. E., Hedblad, B., Illig, T., Jolley, J., Kähönen, M., Kema, I. P., Kemp, J. P., Liang, L., Lloyd-Jones, H., Loos, R. J., Meacham, S., Medland, S. E., Meisinger, C., Memari, Y., Mihailov, E., Miller, K., Moffatt, M. F., Nauck, M., Novatchkova, M., Nutile, T., Olafsson, I., Onundarson, P. T., Parracciani, D., Penninx, B. W. J. H., Perseu, L., Piga, A., Pisits, G., Pouta, A., Puc, U., Raitakari, O., Ring, S. M., Robino, A., Ruggiero, D., Ruokonen, A., Saint-Pierre, A., Sala, C., Salumets, A., Sambrook, J., Schepers, H., Schmidt, C. O., Silljé, H. H., Sladek, R., Smit, J. H., Starr, J. M., Stephens, J., Sulem, P., Tanaka, T., Thorsteinsdottir, U., Tragante, V., van Gilst, W. H., van Pelt, L. J., van Veldhuisen, D. J., Völker, U., Whitfield, J. B., Willemsen, G., Winkelmann, B. R., Wirnsberger, G., Algra, A., Cucca, F., d'Adamo, A. P., Danesh, J., Deary, I. J., Dominiczak, A. F., Elliott, P., Fortina, P., Froguel, P., Gasparini, P., Greinacher, A., Hazen, S. L., Jarvelin, M-R., Khaw, K. T., Lehtimäki, T., Maerz, W., Martin, N. G., Metspalu, A., Mitchell, B. D., Montgomery, G. W., Moore, C., Navis, G., Pirastu, M., Pramstaller, P. P., Ramirez-Solis, R., Schadt, E., Scott, J., Shuldiner, A. R., Smith, G. D., Smith, J. G., Snieder, H., Sorice, R., Spector, T. D., Stefansson, K., Stumvoll, M., Tang, W. H., Toniolo, D., Tönjes, A., Visscher, P. M., Vollenweider, P., Wareham, N. J., Wolffenbuttel, B. H. R., Boomsma, D. I., Beckmann, J. S., Dedoussis, G. V., Deloukas, P., Ferreira, M. A., Sanna, S., Uda, M., Hicks, A. A., Penninger, J. M., Gieger, C., Kooner, J. S., Ouwehand, W. H., Soranzo, N. & Chambers, J. C., 2012, In: Nature. 492, 7429, p. 369-375

    Research output: Contribution to JournalArticleAcademicpeer-review

  • Sex Differences in Genetic Architecture of Complex Phenotypes?

    Vink, J. M., Bartels, M., van Beijsterveldt, C. E. M., van Dongen, J., van Beek, J. H. D. A., Distel, M. A., de Moor, M. H. M., Smit, D. J. A., Minica, C. C., Ligthart, L., Geels, L. M., Abdellaoui, A., Middeldorp, C. M., Hottenga, J. J., Willemsen, G., de Geus, E. J. C. & Boomsma, D. I., 2012, In: PLoS ONE. 7, 12, e47371.

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  • Stable Genetic Effects on Symptoms of Alcohol Abuse and Dependence from Adolescence into Early Adulthood

    van Beek, J. H. D. A., Kendler, K. S., de Moor, M. H. M., Geels, L. M., Bartels, M., Vink, J. M., van den Berg, S. M., Willemsen, G. & Boomsma, D. I., 2012, In: Behavior Genetics. 42, 1, p. 40-56

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  • The Brain Matures with Stronger Functional Connectivity and Decreased Randomness of Its Network

    Smit, D. J. A., Boersma, M., Schnack, H. G., Micheloyannis, S., Boomsma, D. I., Hulshoff Pol, H. E., Stam, C. J. & de Geus, E. J. C., 2012, In: PLoS ONE. 7, 5, p. e36896 e36896.

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  • The continuing value of twin studies in the omics era

    van Dongen, J., Slagboom, P. E., Draisma, H. H. M., Martin, N. G. & Boomsma, D. I., 2012, In: Nature Reviews Genetics. 13, 9, p. 640-653

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  • The Covariation of Trait Anger and Borderline Personality: A Bivariate Twin-Siblings Study

    Distel, M. A., Roeling, M. P., Tielbeek, J. J., van Toor, D., Derom, C. A., Trull, T. J. & Boomsma, D. I., 2012, In: Journal of Abnormal Psychology. 121, 2, p. 458-466

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  • The five factor model of personality and intelligence: A twin study on the relationship between the two constructs

    Bartels, M., van Weegen, F. I., van Beijsterveldt, C. E. M., Carlier, M., Polderman, T. J. C., Hoekstra, R. A. & Boomsma, D. I., 2012, In: Personality and Individual Differences. 53, 4, p. 368-373

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  • The Genetic and Environmental Determinants of the Association Between Brain Abnormalities and Schizophrenia: The Schizophrenia Twins and Relatives Consortium

    van Haren, N. E. M., Rijsdijk, F. V., Schnack, H. G., Picchioni, M., Toulopoulou, T., Weisbrod, M., Sauer, H., van Erp, T. G., Cannon, T. D., Huttunen, M. O., Boomsma, D. I., Hulshoff Pol, H. E., Murray, R. M. & Kahn, R. S., 2012, In: Biological Psychiatry. 71, 10, p. 915-921

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  • Thought problems from adolescence to adulthood: measurement invariance and longitudinal heritability

    Abdellaoui, A., de Moor, M. H. M., Geels, L. M., van Beek, J. H. D. A., Willemsen, G. & Boomsma, D. I., 2012, In: Behavior Genetics. 42, 1, p. 19-29

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