Eline Mertens

2025

Human pyramidal neurons at the center of brain diversity

Mertens, E. J., 13 Feb 2025, 173 p.

Research output: PhD Thesis › PhD-Thesis - Research and graduation internal

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2024

Morpho-electric diversity of human hippocampal CA1 pyramidal neurons

Mertens, E. J., Leibner, Y., Pie, J., Galakhova, A. A., Waleboer, F., Meijer, J., Heistek, T. S., Wilbers, R., Heyer, D., Goriounova, N. A., Idema, S., Verhoog, M. B., Kalmbach, B. E., Lee, B. R., Gwinn, R. P., Lein, E. S., Aronica, E., Ting, J., Mansvelder, H. D., Segev, I., & 1 othersde Kock, C. P. J., 23 Apr 2024, In: Cell Reports. 43, 4, p. 1-16 16 p., 114100.

Research output: Contribution to Journal › Article › Academic › peer-review

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2023

Human voltage-gated Na⁺ and K⁺ channel properties underlie sustained fast AP signaling

Wilbers, R., Metodieva, V. D., Duverdin, S., Heyer, D. B., Galakhova, A. A., Mertens, E. J., Versluis, T. D., Baayen, J. C., Idema, S., Noske, D. P., Verburg, N., Willemse, R. B., de Witt Hamer, P. C., Kole, M. H. P., de Kock, C. P. J., Mansvelder, H. D. & Goriounova, N. A., 13 Oct 2023, In: Science advances. 9, 41, p. 1-14 14 p., eade3300.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

Structural and functional specializations of human fast-spiking neurons support fast cortical signaling

Wilbers, R., Galakhova, A. A., Driessens, S. L. W., Heistek, T. S., Metodieva, V. D., Hagemann, J., Heyer, D. B., Mertens, E. J., Deng, S., Idema, S., de Witt Hamer, P. C., Noske, D. P., van Schie, P., Kommers, I., Luan, G., Li, T., Shu, Y., de Kock, C. P. J., Mansvelder, H. D. & Goriounova, N. A., 13 Oct 2023, In: Science advances. 9, 41, p. 1-15 15 p., eadf0708.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

Genes associated with cognitive ability and HAR show overlapping expression patterns in human cortical neuron types

Driessens, S. L. W., Galakhova, A. A., Heyer, D. B., Pieterse, I. J., Wilbers, R., Mertens, E. J., Waleboer, F., Heistek, T. S., Coenen, L., Meijer, J. R., Idema, S., de Witt Hamer, P. C., Noske, D. P., de Kock, C. P. J., Lee, B. R., Smith, K., Ting, J. T., Lein, E. S., Mansvelder, H. D. & Goriounova, N. A., 13 Jul 2023, In: Nature Communications. 14, p. 1-14 14 p., 4188.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex

Hunt, S., Leibner, Y., Mertens, E. J., Barros-Zulaica, N., Kanari, L., Heistek, T. S., Karnani, M. M., Aardse, R., Wilbers, R., Heyer, D. B., Goriounova, N. A., Verhoog, M. B., Testa-Silva, G., Obermayer, J., Versluis, T., Benavides-Piccione, R., de Witt-Hamer, P., Idema, S., Noske, D. P., Baayen, J. C., & 7 othersLein, E. S., DeFelipe, J., Markram, H., Mansvelder, H. D., Schürmann, F., Segev, I. & de Kock, C. P. J., 15 Mar 2023, In: Cerebral cortex (New York, N.Y. : 1991). 33, 6, p. 2857-2878 22 p.

Research output: Contribution to Journal › Article › Academic › peer-review

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2022

Verbal and General IQ Associate with Supragranular Layer Thickness and Cell Properties of the Left Temporal Cortex

Heyer, D. B., Wilbers, R., Galakhova, A. A., Hartsema, E., Braak, S., Hunt, S., Verhoog, M. B., Muijtjens, M. L., Mertens, E. J., Idema, S., Baayen, J. C., De Witt Hamer, P., Klein, M., Mcgraw, M., Lein, E. S., De Kock, C. P. J., Mansvelder, H. D. & Goriounova, N. A., 1 Jun 2022, In: Cerebral cortex (New York, N.Y. : 1991). 32, 11, p. 2343–2357 15 p., bhab330.

Research output: Contribution to Journal › Article › Academic › peer-review

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Author Correction: Human neocortical expansion involves glutamatergic neuron diversification

Berg, J., Sorensen, S. A., Ting, J. T., Miller, J. A., Chartrand, T., Buchin, A., Bakken, T. E., Budzillo, A., Dee, N., Ding, S. L., Gouwens, N. W., Hodge, R. D., Kalmbach, B., Lee, C., Lee, B. R., Alfiler, L., Baker, K., Barkan, E., Beller, A., Berry, K., & 127 othersBertagnolli, D., Bickley, K., Bomben, J., Braun, T., Brouner, K., Casper, T., Chong, P., Crichton, K., Dalley, R., de Frates, R., Desta, T., Lee, S. D., D’Orazi, F., Dotson, N., Egdorf, T., Enstrom, R., Farrell, C., Feng, D., Fong, O., Furdan, S., Galakhova, A. A., Gamlin, C., Gary, A., Glandon, A., Goldy, J., Gorham, M., Goriounova, N. A., Gratiy, S., Graybuck, L., Gu, H., Hadley, K., Hansen, N., Heistek, T. S., Henry, A. M., Heyer, D. B., Hill, D. J., Hill, C., Hupp, M., Jarsky, T., Kebede, S., Keene, L., Kim, L., Kim, M. H., Kroll, M., Latimer, C., Levi, B. P., Link, K. E., Mallory, M., Mann, R., Marshall, D., Maxwell, M., McGraw, M., McMillen, D., Melief, E., Mertens, E. J., Mezei, L., Mihut, N., Mok, S., Molnar, G., Mukora, A., Ng, L., Ngo, K., Nicovich, P. R., Nyhus, J., Olah, G., Oldre, A., Omstead, V., Ozsvar, A., Park, D., Peng, H., Pham, T., Pom, C. A., Potekhina, L., Rajanbabu, R., Ransford, S., Reid, D., Rimorin, C., Ruiz, A., Sandman, D., Sulc, J., Sunkin, S. M., Szafer, A., Szemenyei, V., Thomsen, E. R., Tieu, M., Torkelson, A., Trinh, J., Tung, H., Wakeman, W., Waleboer, F., Ward, K., Wilbers, R., Williams, G., Yao, Z., Yoon, J. G., Anastassiou, C., Arkhipov, A., Barzo, P., Bernard, A., Cobbs, C., de Witt Hamer, P. C., Ellenbogen, R. G., Esposito, L., Ferreira, M., Gwinn, R. P., Hawrylycz, M. J., Hof, P. R., Idema, S., Jones, A. R., Keene, C. D., Ko, A. L., Murphy, G. J., Ng, L., Ojemann, J. G., Patel, A. P., Phillips, J. W., Silbergeld, D. L., Smith, K., Tasic, B., Yuste, R., Segev, I., de Kock, C. P. J., Mansvelder, H. D., Tamas, G., Zeng, H., Koch, C. & Lein, E. S., 20 Jan 2022, In: Nature. 601, 7893, p. E12-E12 1 p.

Research output: Contribution to Journal › Erratum / Corrigendum › Academic

Open Access

2021

Human neocortical expansion involves glutamatergic neuron diversification

Berg, J., Sorensen, S. A., Ting, J. T., Miller, J. A., Chartrand, T., Buchin, A., Bakken, T. E., Budzillo, A., Dee, N., Ding, S. L., Gouwens, N. W., Hodge, R. D., Kalmbach, B., Lee, C., Lee, B. R., Alfiler, L., Baker, K., Barkan, E., Beller, A., Berry, K., & 127 othersBertagnolli, D., Bickley, K., Bomben, J., Braun, T., Brouner, K., Casper, T., Chong, P., Crichton, K., Dalley, R., de Frates, R., Desta, T., Lee, S. D., D’Orazi, F., Dotson, N., Egdorf, T., Enstrom, R., Farrell, C., Feng, D., Fong, O., Furdan, S., Galakhova, A. A., Gamlin, C., Gary, A., Glandon, A., Goldy, J., Gorham, M., Goriounova, N. A., Gratiy, S., Graybuck, L., Gu, H., Hadley, K., Hansen, N., Heistek, T. S., Henry, A. M., Heyer, D. B., Hill, D. J., Hill, C., Hupp, M., Jarsky, T., Kebede, S., Keene, L., Kim, L., Kim, M. H., Kroll, M., Latimer, C., Levi, B. P., Link, K. E., Mallory, M., Mann, R., Marshall, D., Maxwell, M., McGraw, M., McMillen, D., Melief, E., Mertens, E. J., Mezei, L., Mihut, N., Mok, S., Molnar, G., Mukora, A., Ng, L., Ngo, K., Nicovich, P. R., Nyhus, J., Olah, G., Oldre, A., Omstead, V., Ozsvar, A., Park, D., Peng, H., Pham, T., Pom, C. A., Potekhina, L., Rajanbabu, R., Ransford, S., Reid, D., Rimorin, C., Ruiz, A., Sandman, D., Sulc, J., Sunkin, S. M., Szafer, A., Szemenyei, V., Thomsen, E. R., Tieu, M., Torkelson, A., Trinh, J., Tung, H., Wakeman, W., Waleboer, F., Ward, K., Wilbers, R., Williams, G., Yao, Z., Yoon, J. G., Anastassiou, C., Arkhipov, A., Barzo, P., Bernard, A., Cobbs, C., de Witt Hamer, P. C., Ellenbogen, R. G., Esposito, L., Ferreira, M., Gwinn, R. P., Hawrylycz, M. J., Hof, P. R., Idema, S., Jones, A. R., Keene, C. D., Ko, A. L., Murphy, G. J., Ng, L., Ojemann, J. G., Patel, A. P., Phillips, J. W., Silbergeld, D. L., Smith, K., Tasic, B., Yuste, R., Segev, I., de Kock, C. P. J., Mansvelder, H. D., Tamas, G., Zeng, H., Koch, C. & Lein, E. S., 7 Oct 2021, In: Nature. 598, 7879, p. 151-158 8 p.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

2020

Orange: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons

Willems, J., de Jong, A. P. H., Scheefhals, N., Mertens, E., Catsburg, L. A. E., Poorthuis, R. B., de Winter, F., Verhaagen, J., Meye, F. J. & MacGillavry, H. D., 1 Apr 2020, In: PloS Biology. 18, 4, e3000665.

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access

Eline Mertens

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