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Research Output 2009 2019

2019

Adaption to glucose limitation is modulated by the pleotropic regulator CcpA, independent of selection pressure strength

Price, C. E., Branco Dos Santos, F., Hesseling, A., Uusitalo, J. J., Bachmann, H., Benavente, V., Goel, A., Berkhout, J., Bruggeman, F. J., Marrink, S. J., Montalban-Lopez, M., De Jong, A., Kok, J., Molenaar, D., Poolman, B., Teusink, B. & Kuipers, O. P., 10 Jan 2019, In : BMC Evolutionary Biology. 19, 1, p. 1-15 15 p., 15.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
strength (mechanics)
glucose
mutation
chemostat
fitness
2016

Non-hierarchical flux regulation exposes the fitness burden associated with lactate production in Synechocystis sp PCC6803.

Du, W., Angermayr, S. A., Jongbloets, J. A., Molenaar, D., Bachmann, H., Hellingwerf, K. J. & Santos, F., 2016, In : ACS synthetic biology. 2016/12/12

Research output: Contribution to JournalArticleAcademicpeer-review

Photonfluxostat: A method for light-limited batch cultivation of cyanobacteria at different, yet constant, growth rates.

Du, W., Jongbloets, J. A., Pineda Hernandez, H., Bruggeman, F. J., Hellingwerf, K. J. & Branco dos Santos, F., 2016, In : Algal research. 20, p. 118-125

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Public goods and metabolic strategies

Bachmann, H., Bruggeman, F. J., Molenaar, D., Santos, F. & Teusink, B., Jun 2016, In : Current Opinion in Microbiology. 31, p. 109-115

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
2015

Protein costs do not explain evolution of metabolic strategies and regulation of ribosomal content: does protein investment explain an anaerobic bacterial Crabtree effect?

Goel, A., Eckhardt, T. H., Puri, P., de Jong, A., Santos, F., Giera, M. A., Fusetti, F., Vos, W. M., Kok, J., Poolman, B., Molenaar, D., Kuipers, O. P. & Teusink, B., 2015, In : Molecular Microbiology. 97, p. 77-92 1.

Research output: Contribution to JournalArticleAcademicpeer-review

Fermentation
Costs and Cost Analysis
Glucose
Growth
Proteins
2013

Availability of public goods shapes the evolution of competing metabolic strategies.

Bachmann, H., Fischlechner, M., Rabbers, I., Barfa, N., Branco dos Santos, F., Molenaar, D. & Teusink, B., 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, p. 14302-14307

Research output: Contribution to JournalArticleAcademicpeer-review

biomass
emulsions
organisms
privatization
Lactococcus lactis

Towards metagenome-scale models for industrial applications - the case of Lactic Acid Bacteria

Teusink, B., Branco dos Santos, F. & de Vos, W. M., 2013, In : Current Opinion in Biotechnology. 24, 2, p. 200-206

Research output: Contribution to JournalArticleAcademicpeer-review

Metagenome
Lactic acid
Industrial applications
Lactic Acid
Bacteria
2012

A standardized assay medium to measure enzyme activities of lactococcus lactis while mimicking intracellular conditions.

Goel, A., Santos, F., Vos, W. M., Teusink, B. & Molenaar, D., 2012, In : Applied and Environmental Microbiology. 78, 8, p. 134-143

Research output: Contribution to JournalArticleAcademicpeer-review

Lactococcus lactis
enzyme activity
assay
assays
Enzymes
2011

A practical guide to genome-scale metabolic models and their analysis.

Santos, F., Boele, J. & Teusink, B., 2011, Methods in Enzymology. Jameson, D., Verma, M. & Westerhoff, H. V. (eds.). Burlington: Academic Press, p. 509-532 (Methods in Systems Biology; no. 500).

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

Explorin metabolic pathway reconstruction and genome-wide expression profiling in lactobacillus reuteri to define functional probiotic features.

Saulnier, D. M. A., Santos, F., Roos, S., Mistretta, T-A., Spinler, J. K., Molenaar, D., Teusink, B. & Versalovic, J., 2011, In : PLoS ONE. 6, p. e18783

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Lactobacillus reuteri
Probiotics
Metabolic Networks and Pathways
probiotics
biochemical pathways

Functional Identification in Lactobacillus reuteri of a PocR-like transcription factor regulating glycerol utilization and vitamin B12 synthesis.

Santos, F., Spinler, J. K., Saulnier, D. M. A., Molenaar, D., Teusink, B., de Vos, D. L., Versalovic, J. & Hugenholtz, J., 2011, In : Microbial Cell Factories. 10, p. 55

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Lactobacillus reuteri
Vitamin B Complex
Transcription factors
Vitamins
Vitamin B 12
2009

Effect of amino acid availability on vitamin B12 production in Lactobacillus reuteri.

Santos, F., Teusink, B., Molenaar, D., van Heck, M., Sieuwerts, S., de Vos, W. M. & Hugenholtz, J., 2009, In : Applied and Environmental Microbiology. 75, p. 3930-3936

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Lactobacillus reuteri
vitamin B12
Vitamin B 12
Genomics
vitamin

The evidence that pseudovitamin B12 is biologically active in mammals is still lacking.

Santos, F., Teusink, B., de Vos, W. M. & Hugenholtz, J., 2009, In : Journal of Applied Microbiology. 107, p. 1763-1763

Research output: Contribution to JournalArticleAcademicpeer-review