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Fiona Hagenbeek (1989) is a postdoctoral researcher at the Department of Biological Psychology and the Netherlands Twin Register (NTR) at the Vrije Universiteit Amsterdam, where she also obtained her PhD. During her PhD she pursued two related research lines. First, she investigated the link between genetics and metabolomics by studying the contribution of genes and environment to blood metabolite levels in adult populations. Second, she focused on biomarker discovery for (childhood) aggression. As part of the EU-funded ACTION project (Aggression in Children: Unraveling gene-environment interplay to inform Treatment and InterventiON strategies), she developed protocols for the collection of urine and buccal-cell samples in children (http://www.action-euproject.eu/content/data-protocols). She applied these protocols in a large cohort of twin children of the NTR and obtained genome-wide SNP and DNA methylation data from the buccal cells and urinary metabolites from three metabolomics platforms. With these datasets, she contributed to genetic, epigenetic, and metabolomic efforts for the discovery of omics markers for (childhood) aggression. Her current research focuses on integrating transmitted and non-transmitted polygenic scores together with DNA methylation and metabolomics data to investigate the intergenerational transmission of (externalizing) behavior problems in children.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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DNA methylation in peripheral tissues and left-handedness
Odintsova, V. V., Hagenbeek, F. A., Hottenga, J. J., Pool, R., Dolan, C. V., Ligthart, L., van Beijsterveldt, C. E. M., Willemsen, G., de Geus, E. J. C., Beck, J. J., Ehli, E. A., Boomsma, D. I., van Dongen, J. & BIOS Consortium, 4 Apr 2022, In: Scientific Reports. 12, 1, p. 1-16 16 p., 5606.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Genome-wide association meta-analysis identifies 29 new acne susceptibility loci
Mitchell, B. L., Saklatvala, J. R., Dand, N., Hagenbeek, F. A., Li, X., Min, J. L., Thomas, L., Bartels, M., Jan Hottenga, J., Lupton, M. K., Boomsma, D. I., Dong, X., Hveem, K., Løset, M., Martin, N. G., Barker, J. N., Han, J., Smith, C. H., Rentería, M. E. & Simpson, M. A., 7 Feb 2022, (E-pub ahead of print) In: Nature Communications. 13, p. 1-9 9 p., 702.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Genome-wide Association Meta-analysis of Childhood and Adolescent Internalizing Symptoms
Jami, E. S., Hammerschlag, A. R., Ip, H. F., Allegrini, A. G., Benyamin, B., Border, R., Diemer, E. W., Jiang, C., Karhunen, V., Lu, Y., Lu, Q., Mallard, T. T., Mishra, P. P., Nolte, I. M., Palviainen, T., Peterson, R. E., Sallis, H. M., Shabalin, A. A., Tate, A. E., Thiering, E., & 74 others, Jul 2022, In: Journal of the American Academy of Child and Adolescent Psychiatry. 61, 7, p. 934-945 12 p.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Heritability of Urinary Amines, Organic Acids, and Steroid Hormones in Children
Hagenbeek, F. A., van Dongen, J., Pool, R., Harms, A. C., Roetman, P. J., Fanos, V., van Keulen, B. J., Walker, B. R., Karu, N., Hulshoff Pol, H. E., Rotteveel, J., Finken, M. J. J., Vermeiren, R. R. J. M., Kluft, C., Bartels, M., Hankemeier, T. & Boomsma, D. I., Jun 2022, In: Metabolites. 12, 6, p. 1-17 17 p., 474.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Integrative Multi-omics Analysis of Childhood Aggressive Behavior
Hagenbeek, F. A., van Dongen, J., Pool, R., Roetman, P. J., Harms, A. C., Hottenga, J. J., Kluft, C., Colins, O. F., van Beijsterveldt, C. E. M., Fanos, V., Ehli, E. A., Hankemeier, T., Vermeiren, R. R. J. M., Bartels, M., Déjean, S. & Boomsma, D. I., 7 Nov 2022, (E-pub ahead of print) In: Behavior Genetics.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access
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Urinary biomarkers and metabolites of childhood aggression
Fiona Hagenbeek (Speaker)
8 May 2019Activity: Lecture / Presentation › Academic
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UseR!2019
Fiona Hagenbeek (Organiser)
9 Jul 2019 → 12 Jul 2019Activity: Participating in or organising an event › Conference › Academic
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Onderzoek naar agressie bij kinderen in het Nederlands Tweelingen Register: Het ACTION project
Fiona Hagenbeek (Speaker)
30 Sep 2018Activity: Lecture / Presentation › Professional
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Multi-omics biomarker discovery for childhood aggression
Fiona Hagenbeek (Speaker)
22 Nov 2018Activity: Lecture / Presentation › Academic
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Metabolomics in Children and Adults
F.A. Hagenbeek (Speaker)
30 Jun 2017Activity: Lecture / Presentation › Academic