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Group Page: Gijs Wuite Laboratory

Gijs Wuite obtained his PhD in biophysics in 2000. Since 2001 he leads his own group at the Vrije Universiteit Amsterdam and in 2009 was appointed full professor. In his research he has successfully applied quantitative physical tools to investigate fundamental problems in biology, and to search for the unification of apparently unrelated biological phenomena. Moreover, he has been at the forefront of recent new and fast developments of biophysical techniques that have enabled visualization, manipulation and control of complex biological reactions. In 2014 he co-founded LUMICKS, a fast growing company specialized in dynamic single molecule instruments and in 2018 he won the Dutch Physics Valorisation prize & in 2019 the Amsterdam Impact Award, for successfully launching this company.

Notable is his publication in 2013 (Nature Method) on STED with optical tweezers in collaboration with Prof. Hell (Nobel laureate) and his 2016 Nature paper describing the integration of a multi-beam optical trap capable of handling multiple DNA molecules with fluorescence microscopy. Another key innovation is the invention of a new class of biophysical instrumentation, Acoustic Force Spectroscopy, which is making a big impact with research groups across the world implementing this technology. 

Wuite has received many awards and fellowships for his scientific work, including a NWO-VICI (2008) grant, an ERC Consolidator (2010) and ERC Advanced (2020) Grant of the European Union. The Amsterdam Impact Award (2019) for the most innovative scientific idea in Amsterdam. He obtained the NWO Physics Valorisation Prize (2017). He was one of the WEF “2013 Young Scientist”. Wuite was an elected member (2009) of the Young Academy (DJA), part of the Royal Dutch Academy of Sciences (KNAW). He is an elected member (2014) of the Global Young Academy; he served on the management boards of both.

Research

The research themes of the group are currently focused on unraveling the mechanics and dynamics of biological systems using an array of experimental techniques such as AFM, AFS, optical tweezers and (single-molecule) fluorescence. By investigating increasingly complex biological processes, we aim to link single molecule research with experimental systems biology. Most of our biophysical questions are solved in collaboration with biochemists, biologists, theoretical physicists and physicians.  

Gijs Wuite | Physics Living Systems | Department of Physics and Astronomy

 

Teaching

Optics

Soft Condensed Matter and Biological Physics

Master thesis supervisor for Science Business Innovation Program.

Ancillary activities

  • Lumicks BV | Amsterdam | | 2014-01-01 - present
  • GW Instruments | Amsterdam | Directeur/eigenaar | 2014-01-01 - present

Ancillary activities are updated daily

Keywords

  • Q Science (General)
  • Mechanics of biological systems
  • Optical Tweezers
  • Acoustic Force Spectroscopy (AFS)
  • Single-Molecule fluorescence
  • Complex biological processes
  • Experimental systems biology
  • Chromosome dynamics
  • Protein dynamics
  • Chromosome mechanics
  • Physics of living systems
  • Optical trapping
  • Superresolution detection
  • Biophysical instrumentation
  • Physics of viruses
  • Biological materials evolution
  • Viral genetic material
  • ATmoic Force Microscopy (AFM)

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being
  2. SDG 7 - Affordable and Clean Energy
    SDG 7 Affordable and Clean Energy

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