prof. dr. G.W. Somsen

prof. dr.

1988 …2020
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Personal profile

Ancillary activities

  • Journal of Chromatography B | Amsterdam | Editor | 2016-01-01 - present
  • NWO Study Group Analytical Chemistry | Den Haag | Board member | 2016-01-01 - present
  • KNCV CE User Group | Den Haag | Chairman board | 2017-01-01 - present
  • Society for Microscale Separation and Bioanalysis (SMSB) | Pittsburgh | Board director | 2018-03-01 - present
  • KNCV Working Group Separation Sciences | Den Haag | Member of board | 2018-04-11 - present

Ancillary activities are updated daily

Personal information

Govert Somsen is full professor of Biomolecular Analysis/Analytical Chemistry at VU Amsterdam since 2013. He obtained his doctorate at VU in 1997, and subsequently was assistant and associate professor at the University of Groningen (1996-2001) and at Utrecht University (2001-2012).


Somsen's current research interests include compositional and conformational characterization of intact biomacromolecules, bioactivity screening of compounds in complex samples, and metabolite analysis with particular attention for compound chirality. His group built an internationally recognized expertise in the hyphenation of capillary electrophoresis with mass spectrometry and optical spectroscopy for the analysis of pharmaceutical proteins. Somsen is (co)author of over 155 peer-reviewed papers and has an H-index of 34 (Nov 2017).


2015   Personal leadership, VU Amsterdam
2012   Academic leadership, Utrecht University
2004   Senior qualification research, Utrecht University
2003   Basic qualification teaching, Utrecht University
2000   Time management for researchers, University of Groningen
1997   Doctorate, VU Amsterdam; promotor: Prof dr U.A.Th. Brinkman
Thesis: Solvent-elimination-based coupling of column liquid chromatography and vibrational-spectroscopic detection techniques
1989   Chemistry (MSc), VU Amsterdam; major: Analytical Chemistry and Applied Spectroscopy; minor: Environmental Chemistry
1986   Chemistry teaching qualification (first degree), VU Amsterdam
1984   Chemistry (BSc), VU Amsterdam

Ancillary activities

• Editor of Journal of Chromatography B.
• Chairman of the Dutch CE users group (KNCV).
• Member of the board of the Working Group Separation Science (KNCV).
• Member of the board of the Society of Microscale Separations and Bioanalysis.
• Member of the organizing committee of the 9th International Symposium on the Separation and Characterization of Natural and Synthetic Macromolecules 2019.

• Board member of the NWO Study group Analytical Chemistry.
• Member of the scientific committee of Drug Analysis/PBA 2018.
• Co-chair of the global CESI-MS Symposium 2018.
• Guest editor of Journal of Chromatpgraphy A (2017).
• Chairman of the 33rd International Symposium on Microscale Separations and Bioanalysis (MSB 2017).
• Member of the scientific committee of Recent Developments in Pharmaceutical Analysis 2017.


Currently lecturing:

  • Analytical Chemistry and Spectroscopy (BSc Chem).
  • Identification Techniques (BSc FAR).
  • Biopharmaceuticals (BSc FAR).
  • Advanced Separation Science (MSc Chem).
  • (Bio)Molecular Spectroscopy (MSc Chem).
  • Protein Analysis (MSc Chem).

Fingerprint Dive into the research topics where G.W. Somsen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 8 Similar Profiles
Capillary electrophoresis Chemical Compounds
Mass spectrometry Chemical Compounds
Capillary Electrophoresis Medicine & Life Sciences
Mass Spectrometry Medicine & Life Sciences
Liquid chromatography Chemical Compounds
Liquid Chromatography Medicine & Life Sciences
Chromatography Chemical Compounds
Proteins Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1988 2020

Analytics for bioactivity profiling of complex mixtures with a focus on venoms

Mladic, M., Niessen, W. M. A., Somsen, G. W. & Kool, J., 1 Jan 2020, Snake and spider toxins: methods and protocols. Humana Press Inc., p. 27-49 23 p. (Methods in Molecular Biology; vol. 2068).

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

Drug Discovery
Complex Mixtures
Biological Products
Biological Assay

Identification of mutagenic and endocrine disrupting compounds in surface water and wastewater treatment plant effluents using high-resolution effect-directed analysis

Zwart, N., Jonker, W., Broek, R. T., de Boer, J., Somsen, G., Kool, J., Hamers, T., Houtman, C. J. & Lamoree, M. H., 1 Jan 2020, In : Water Research. 168, p. 1-9 9 p., 115204.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Water treatment
Surface waters
Wastewater treatment

Advancing analytical tools and methods for bioactivity profiling of complex samples: Application to drug metabolic mixtures and snake venoms

Zietek, B. M., 2019, 221 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access

Bioactivity profiling of small-volume samples by nano liquid chromatography coupled to microarray bioassaying using high-resolution fractionation

Zietek, B. M., Still, K. B. M., Jaschusch, K., Bruyneel, B., Ariese, F., Brouwer, T. J. F., Luger, M., Limburg, R. J., Rosier, J. C., Dick, D. J., Casewell, N. R., Somsen, G. W. & Kool, J., 20 Aug 2019, In : Analytical Chemistry. 91, 16, p. 10441-10447 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Liquid chromatography

CE-MS for metabolomics: Developments and applications in the period 2016–2018

Ramautar, R., Somsen, G. W. & de Jong, G. J., 1 Jan 2019, In : Electrophoresis. 40, 1, p. 165-179 15 p.

Research output: Contribution to JournalReview articleAcademicpeer-review

Open Access