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Research Output 2004 2019

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Article
2019

Comparing factor structures of depressed patients with and without suicidal ideation, a measurement invariance analysis

van Ballegooijen, W., Eikelenboom, M., Fokkema, M., Riper, H., van Hemert, A. M., Kerkhof, A. J. F. M., Penninx, B. W. J. H. & Smit, J. H., 15 Feb 2019, In : Journal of Affective Disorders. 245, p. 180-187 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Suicidal Ideation
Depression
Statistical Factor Analysis
Anxiety
Major Depressive Disorder

Do Nonsuicidal Severely Depressed Individuals with Diabetes Profit from Internet-Based Guided Self-Help? Secondary Analyses of a Pragmatic Randomized Trial

Schlicker, S., Weisel, K. K., Buntrock, C., Berking, M., Nobis, S., Lehr, D., Baumeister, H., Snoek, F. J., Riper, H. & Ebert, D. D., 1 Jan 2019, In : Journal of diabetes research. 2019, 1 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Pragmatic Clinical Trials
Internet
Depression
Confidence Intervals
Control Groups

Economic evaluation of an internet-based stress management intervention alongside a randomized controlled trial

Kählke, F., Buntrock, C., Smit, F., Berking, M., Lehr, D., Heber, E., Funk, B., Riper, H. & Ebert, D. D., 1 May 2019, In : Journal of Medical Internet Research. 21, 5, e10866.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Internet
Cost-Benefit Analysis
Randomized Controlled Trials
Costs and Cost Analysis
Quality-Adjusted Life Years

Efficacy and cost-effectiveness of guided and unguided internet- and mobile-based indicated transdiagnostic prevention of depression and anxiety (ICare Prevent): A three-armed randomized controlled trial in four European countries

Weisel, K. K., Zarski, A-C., Berger, T., Krieger, T., Schaub, M. P., Moser, C. T., Berking, M., Dey, M., Botella, C., Baños, R., Herrero, R., Etchemendy, E., Riper, H., Cuijpers, P., Bolinski, F., Kleiboer, A., Görlich, D., Beecham, J., Jacobi, C. & Ebert, D. D., Apr 2019, In : Internet Interventions. 16, p. 52-64 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Internet
Cost-Benefit Analysis
Anxiety
Randomized Controlled Trials
Depression

Examining the effectiveness of a web-based intervention for symptoms of depression and anxiety in college students: Study protocol of a randomised controlled trial

Karyotaki, E., Klein, A. M., Riper, H., Wit, L. D., Krijnen, L., Bol, E., Bolinski, F., Burger, S., Ebert, D. D., Auerbach, R. P., Kessler, R. C., Bruffaerts, R., Batelaan, N., Van Der Heijde, C. M., Vonk, P., Kleiboer, A., Wiers, R. W. & Cuijpers, P., 1 May 2019, In : BMJ Open. 9, 5, 028739.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Anxiety
Randomized Controlled Trials
Depression
Students
Mental Disorders

GPS' attitudes towards digital technologies for depression: An online survey in primary care

Breedvelt, J. J. F., Zamperoni, V., Kessler, D., Riper, H., Kleiboer, A. M., Elliott, I., Abel, K. M., Gilbody, S. & Bockting, C. L. H., Mar 2019, In : British Journal of General Practice. 69, 680, p. e164-e170 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Primary Health Care
Mental Health
Depression
Technology
Surveys and Questionnaires
Open Access
Internet
Anxiety
Depression
Students
Indonesia

Guided or self-guided internet-based cognitive-behavioural therapy (iCBT) for depression? Study protocol of an individual participant data network meta-analysis

Karyotaki, E., Furukawa, T. A., Efthimiou, O., Riper, H. & Cuijpers, P., 1 Jun 2019, In : BMJ Open. 9, 6, e026820.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Cognitive Therapy
Internet
Depression
Databases
Peer Review

Heterogeneity Matters: Predicting Self-Esteem in Online Interventions Based on Ecological Momentary Assessment Data

Bremer, V., Funk, B. & Riper, H., 13 Jan 2019, In : Depression research and treatment. 2019, p. 1-9 9 p., 3481624.

Research output: Contribution to JournalArticleAcademicpeer-review

Self Concept
Internet
Sleep
Depression
Ecological Momentary Assessment

Toward an Objective Assessment of Implementation Processes for Innovations in Health Care: Psychometric Evaluation of the Normalization Measure Development (NoMAD) Questionnaire Among Mental Health Care Professionals

Vis, C., Ruwaard, J., Finch, T., Rapley, T., de Beurs, D., van Stel, H., van Lettow, B., Mol, M., Kleiboer, A., Riper, H. & Smit, J., 20 Feb 2019, In : Journal of Medical Internet Research. 21, 2, p. e12376

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Process Assessment (Health Care)
Psychometrics
Mental Health
Delivery of Health Care
Statistical Factor Analysis

Unraveling the Black Box: Exploring Usage Patterns of a Blended Treatment for Depression in a Multicenter Study

Kemmeren, L. L., van Schaik, A., Smit, J. H., Ruwaard, J., Rocha, A., Henriques, M., Ebert, D. D., Titzler, I., Hazo, J-B., Dorsey, M., Zukowska, K. & Riper, H., 25 Jul 2019, In : JMIR mental health. 6, 7, p. e12707

Research output: Contribution to JournalArticleAcademicpeer-review

Multicenter Studies
Depression
Cognitive Therapy
Mental Health
Delivery of Health Care

Validating automated sentiment analysis of online cognitive behavioral therapy patient texts: An exploratory study

Provoost, S., Ruwaard, J., van Breda, W., Riper, H. & Bosse, T., 14 May 2019, In : Frontiers in Psychology. 10, MAY, p. 1-12 12 p., 1065.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Cognitive Therapy
Emotions
Benchmarking
Psychology
Consensus

Working alliance as a predictor of change in depression during blended cognitive behaviour therapy

On behalf of the E-COMPARED consortium, 4 Jul 2019, In : Cognitive Behaviour Therapy. 48, 4, p. 285-299 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Cognitive Therapy
Depression
Therapeutics
Internet
Growth
2018

A health economic outcome evaluation of an internet-based mobile-supported stress management intervention for employees

Ebert, D. D., Kählke, F., Buntrock, C., Berking, M., Smit, F., Heber, E., Baumeister, H., Funk, B., Riper, H. & Lehr, D., Apr 2018, In : Scandinavian Journal of Work, Environment and Health. 44, 2, p. 171-182 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Internet
Cost-Benefit Analysis
Health
Random Allocation
Costs and Cost Analysis

A patient post hoc perspective on advantages and disadvantages of blended cognitive behaviour therapy for depression: A qualitative content analysis

Urech, A., Krieger, T., Möseneder, L., Biaggi, A., Vincent, A., Poppe, C., Meyer, B., Riper, H. & Berger, T., 31 Jan 2018, In : Psychotherapy Research. p. 1-13 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Cognitive Therapy
Depression
Internet
Therapeutics

Barriers and facilitators for the implementation of blended psychotherapy for depression: A qualitative pilot study of therapists' perspective

Titzler, I., Saruhanjan, K., Berking, M., Riper, H. & Ebert, D. D., Jun 2018, In : Internet Interventions. 12, p. 150-164 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Psychotherapy
Depression
Therapeutics
Internet
Interviews

Behind the scenes of online therapeutic feedback in blended therapy for depression: Mixed-methods observational study

Mol, M., Dozeman, E., Provoost, S., Van Schaik, A., Riper, H. & Smit, J. H., 3 May 2018, In : Journal of Medical Internet Research. 20, 5, p. 1-11 11 p., e174.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Observational Studies
Depression
Therapeutics
Cognitive Therapy
Internet

Development and testing of TraumaGameplay: An iterative experimental approach using the trauma film paradigm.

Asselbergs, J., Sijbrandij, M., Hoogendoorn, E., Cuijpers, P., Olie, L., Oved, K., Merkies, J., Plooijer, T., Eltink, S. & Riper, H., 5 Feb 2018, In : European Journal of Psychotraumatology. 9, 1, p. 1-15 14 p., 1424447.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Post-Traumatic Stress Disorders
Wounds and Injuries
Students
Motion Pictures
Short-Term Memory

Economic Evaluation of an Internet-Based Preventive Cognitive Therapy With Minimal Therapist Support for Recurrent Depression: Randomized Controlled Trial

Klein, N. S., Bockting, C. L., Wijnen, B., Kok, G. D., van Valen, E., Riper, H., Cuijpers, P., Dekker, J., van der Heiden, C., Burger, H. & Smit, F., Nov 2018, In : Journal of Medical Internet Research. 20, 11, p. 1-14 14 p., e10437.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Cognitive Therapy
Internet
Cost-Benefit Analysis
Randomized Controlled Trials
Depression

Economic evaluation of an internet-based preventive cognitive therapy with minimal therapist support for recurrent depression: results of a randomized controlled trial.

Klein, N. S., Bockting, C. L. H., Wijnen, B., Kok, G. D., van Valen, E., Riper, H., Cuijpers, P., Dekker, J., van der Heiden, C., Burger, H. & Smit, F., 26 Nov 2018, In : Journal of Medical Internet Research. 20, 11, p. 1-14 14 p., e10437.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Cognitive Therapy
Internet
Cost-Benefit Analysis
Randomized Controlled Trials
Depression

Effectiveness and treatment moderators of internet interventions for adult problem drinking: An individual patient data meta-analysis of 19 randomised controlled trials

Riper, H., Hoogendoorn, A., Cuijpers, P., Karyotaki, E., Boumparis, N., Mira, A., Andersson, G., Berman, A. H., Bertholet, N., Bischof, G., Blankers, M., Boon, B., Boß, L., Brendryen, H., Cunningham, J., Ebert, D., Hansen, A., Hester, R., Khadjesari, Z., Kramer, J. & 10 othersMurray, E., Postel, M., Schulz, D., Sinadinovic, K., Suffoletto, B., Sundström, C., de Vries, H., Wallace, P., Wiers, R. W. & Smit, J. H., 18 Dec 2018, In : PLoS Medicine. 15, 12, p. 1-26 26 p., e1002714.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Internet
Drinking
Meta-Analysis
Randomized Controlled Trials
Odds Ratio
Open Access
File
Internet
Anxiety
Randomized Controlled Trials
Depression
Students

Effectiveness of Web- and Mobile-Based Treatment of Subthreshold Depression With Adherence-Focused Guidance: A Single-Blind Randomized Controlled Trial

Ebert, D. D., Buntrock, C., Lehr, D., Smit, F., Riper, H., Baumeister, H., Cuijpers, P. & Berking, M., Jan 2018, In : Behavior Therapy. 49, 1, p. 71-83 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Randomized Controlled Trials
Depression
Equipment and Supplies
Major Depressive Disorder
Sleep Initiation and Maintenance Disorders

Efficacy and cost-effectiveness of a blended cognitive behavioral therapy for depression in Spanish primary health care: Study protocol for a randomised non-inferiority trial

Vara, M. D., Herrero, R., Etchemendy, E., Espinoza, M., Baños, R. M., García-Palacios, A., Lera, G., Folch, B., Palop-Larrea, V., Vázquez, P., Franco-Martín, M., Kleiboer, A., Riper, H. & Botella, C., 23 Mar 2018, In : BMC Psychiatry. 18, p. 1-9 9 p., 74.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Cognitive Therapy
Cost-Benefit Analysis
Primary Health Care
Depression
Therapeutics

Efficacy of a web-based intervention with and without guidance for employees with risky drinking: results of a three-arm randomized controlled trial

Boß, L., Lehr, D., Schaub, M. P., Paz Castro, R., Riper, H., Berking, M. & Ebert, D. D., Apr 2018, In : Addiction. 113, 4, p. 635-646 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Drinking
Randomized Controlled Trials
Alcohols
Mental Health
Alcohol Drinking

Guided Internet-Based Cognitive Behavioral Therapy for Adult Depression and Anxiety in Routine Secondary Care: Observational Study

Mathiasen, K., Riper, H., Andersen, T. E. & Roessler, K. K., 28 Nov 2018, In : Journal of Medical Internet Research. 20, 11, p. 1-14 14 p., e10927.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Secondary Care
Cognitive Therapy
Internet
Observational Studies
Anxiety

Is self-guided internet-based cognitive behavioural therapy (iCBT) harmful? An individual participant data meta-analysis

Karyotaki, E., Kemmeren, L., Riper, H., Twisk, J., Hoogendoorn, A., Kleiboer, A., Mira, A., Mackinnon, A., Meyer, B., Botella, C., Littlewood, E., Andersson, G., Christensen, H., Klein, J. P., Schröder, J., Bretón-López, J., Scheider, J., Griffiths, K., Farrer, L., Huibers, M. J. H. & 7 othersPhillips, R., Gilbody, S., Moritz, S., Berger, T., Pop, V., Spek, V. & Cuijpers, P., Nov 2018, In : Psychological Medicine. 48, 15, p. 2456-2466 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Cognitive Therapy
Internet
Meta-Analysis
Depression
Watchful Waiting

Predicting short term mood developments among depressed patients using adherence and ecological momentary assessment data

Mikus, A., Hoogendoorn, M., Rocha, A., Gama, J., Ruwaard, J. & Riper, H., Jun 2018, In : Internet Interventions. 12, p. 105-110 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Patient Compliance
Cell Phones
Artificial Intelligence
Major Depressive Disorder
Diagnostic and Statistical Manual of Mental Disorders

Predicting therapy success and costs for personalized treatment recommendations using baseline characteristics: Data-driven analysis

Bremer, V., Becker, D., Kolovos, S., Funk, B., Van Breda, W., Hoogendoorn, M. & Riper, H., 21 Aug 2018, In : Journal of Medical Internet Research. 20, 8, p. 1-11 11 p., e10275.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Health Care Costs
Costs and Cost Analysis
Therapeutics
Cost-Benefit Analysis
Decision Making

Reducing distress and improving social functioning in daily life in people with auditory verbal hallucinations: Study protocol for the Temstem' randomised controlled trial

Jongeneel, A., Scheffers, D., Tromp, N., Nuij, C., Delespaul, P., Riper, H., Van Der Gaag, M. & van den Berg, D., Mar 2018, In : BMJ Open. 8, 3, p. 1-10 10 p., e020537.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Hallucinations
Randomized Controlled Trials
Ethics Committees
Medical Ethics
Cognitive Therapy

Severely burdened individuals do not need to be excluded from internet-based and mobile-based stress management: Effect modifiers of treatment outcomes from three randomized controlled trials

Weisel, K. K., Lehr, D., Heber, E., Zarski, A. C., Berking, M., Riper, H. & Ebert, D. D., 19 Jun 2018, In : Journal of Medical Internet Research. 20, 6, p. 1-15 15 p., e211.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Internet
Randomized Controlled Trials
Anxiety
Depression
Clinical Trials

Six-year healthcare trajectories of adults with anxiety and depressive disorders: Determinants of transition to specialised mental healthcare

Kooistra, L. C., Wiersma, J. E., Ruwaard, J. J., Riper, H., Penninx, B. W. J. H. & van Oppen, P., 1 Dec 2018, In : Journal of Affective Disorders. 241, p. 226-234 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Depressive Disorder
Anxiety Disorders
Delivery of Health Care
Self Report
Primary Health Care

Smartphone-based safety planning and self-monitoring for suicidal patients: Rationale and study protocol of the CASPAR (Continuous Assessment for Suicide Prevention And Research) study

Nuij, C., van Ballegooijen, W., Ruwaard, J., de Beurs, D., Mokkenstorm, J., van Duijn, E., de Winter, R. F. P., O'Connor, R. C., Smit, J. H., Riper, H. & Kerkhof, A., 1 Sep 2018, In : Internet Interventions. 13, p. 16-23 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Physiologic Monitoring
Suicide
Safety
Research
Medical Ethics

Using multi-relational data mining to discriminate blended therapy efficiency on patients based on log data

Rocha, A., Camacho, R., Ruwaard, J. & Riper, H., Jun 2018, In : Internet Interventions. 12, p. 176-180 5 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Data Mining
Self Report
Therapeutics
Depression
Information Storage and Retrieval

Web-based intervention for depressive symptoms in adults with types 1 and 2 diabetes mellitus: A health economic evaluation

Nobis, S., Ebert, D. D., Lehr, D., Smit, F., Buntrock, C., Berking, M., Baumeister, H., Snoek, F., Funk, B. & Riper, H., Apr 2018, In : British Journal of Psychiatry. 212, 4, p. 199-206 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Type 1 Diabetes Mellitus
Type 2 Diabetes Mellitus
Cost-Benefit Analysis
Depression
Health
2017

Effectiveness and cost-effectiveness of a guided internet- and mobile-based depression intervention for individuals with chronic back pain: Protocol of a multi-centre randomised controlled trial

Lin, J., Sander, L., Paganini, S., Schlicker, S., Ebert, D., Berking, M., Bengel, J., Nobis, S., Lehr, D., Mittag, O., Riper, H. & Baumeister, H., 1 Dec 2017, In : BMJ Open. 7, 12, e015226.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Back Pain
Chronic Pain
Internet
Cost-Benefit Analysis
Randomized Controlled Trials

In Reply [to] Internet-based self-help interventions for depression in routine care

Karyotaki, E., Riper, H. & Cuijpers, P., 2017, In : JAMA Psychiatry. 74, 8, p. 853-853 1 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2016

Blended CBT versus face-to-face CBT: a randomised non-inferiority trial.

Mathiasen, K., Andersen, T. E., Riper, H., Kleiboer, A. & Roessler, K. K., 2016, In : BMC Psychiatry. 16, 1, p. 432

Research output: Contribution to JournalArticleAcademicpeer-review

Development and initial evaluation of blended cognitive behavioural treatment for Major Depression in Routine Specialized Mental Health Care

Kooistra, L. C., Ruwaard, J., Wiersma, J. E., van Oppen, P., van der Vaart, R., Van Gemert-Pijnen, L. & Riper, H., 2016, In : Internet Interventions. 4

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Does Internet-based guided-self-help for depression cause harm? An individual participant data meta-analysis on deterioration rates and its moderators in randomized controlled trials.

Ebert, D. D., Donkin, L. J., Andersson, G., Andrews, G., Berger, T., Carlbring, P., Rozenthal, A., Choi, I., Laferton, J. A., Johansson, R., Kleiboer, A. M., Lange, A., Lehr, D., Reins, J. A., Funk, B., Newby, J., Perini, S., Riper, H., Ruwaard, J. J., Sheeber, L. & 9 othersSnoek, F. J., Titov, N., Ünlü Ince, B., Van Bastelaar, K., Vernmark, K., van Straten, A., Warmerdam, L., Salsman, N. & Cuijpers, P., 2016, In : Psychological Medicine. 46, 13, p. 2679-93

Research output: Contribution to JournalArticleAcademicpeer-review

E-care 4 caregivers- an online intervention for non-professional caregivers of depressed patients: study protocol for a pilot randomized controlled trial.

Bijker, L., Kleiboer, A., Riper, H., Cuijpers, P. & Donker, T., 11 Apr 2016, In : Trials. 17, p. 193 17.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Effectiveness of blended depression treatment for adults in specialised mental healthcare: study protocol for a randomised controlled trial.

Kemmeren, L. L., van Schaik, D. J., Riper, H., Kleiboer, A. M., Bosmans, J. E. & Smit, J. H., 2016, In : BMC Psychiatry. 16, 1, p. 113

Research output: Contribution to JournalArticleAcademicpeer-review

Effect of a web-based guided self-help intervention for prevention of major depression in adults with sub-threshold depression: A randomized clinical trial.

Buntrock, C., Ebert, D. D., Lehr, D., Smit, F., Riper, H., Berking, M. & Cuijpers, P., 2016, In : JAMA. 315, 17, p. 1854-63 315.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Efficacy of an internet-based self-help intervention to reduce co-occurring alcohol misuse and depression symptoms in adults: study protocol of a three-arm randomised controlled trial

Schaub, M. P., Blankers, M., Lehr, D., Boss, L., Riper, H., Dekker, J., Goudriaan, A. E., Maier, L. J., Haug, S., Amann, M., Dey, M., Wenger, A. & Ebert, D. D., 2016, In : BMJ Open. 6, 5, p. e011457

Research output: Contribution to JournalArticleAcademicpeer-review

European COMPARative Effectiveness research on blended Depression treatment versus treatment-as-usual (E-COMPARED): study protocol for a randomized controlled, non-inferiority trial in eight European countries

Kleiboer, A. M., Smit, J., Bosmans, J., Ruwaard, J., Andersson, G., Topooco, N., Berger, T., Krieger, T., Botella, C., Banos, R., Chevreul, K., Araya, R., Cerga-Pashoja, A., Cieslak, R., Rogala, A., Vis, C., Draisma, S., Van Schaik, A., Kemmeren, L., Ebert, D. & 4 othersBerking, M., Funk, B., Cuijpers, P. & Riper, H., 3 Aug 2016, In : Trials. 17, p. 1-10 10 p., 387.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Depression
Research
Netherlands
Cost-Benefit Analysis
Mental Health

Internet-based CBT for social phobia and panic disorder in a specialised anxiety clinic in routine care: Results of a pilot randomised controlled trial.

Mathiasen, K., Riper, H., Ehlers, L. H., Valentin, J. B. & Rosenberg, N. K., 2016, In : Internet Interventions. 4, p. 92-98

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Internet-based cognitive behavioral therapy for insomnia: a health economic evaluation.

Thiart, H., Ebert, D. D., Lehr, D., Nobis, S., Buntrock, C., Berking, M., Smit, F. & Riper, H., 2016, In : SLEEP. 39, 10, p. 1769-1778

Research output: Contribution to JournalArticleAcademicpeer-review

Langzeiteffekte eines Online-Trainings zur Reduktion von depressiven Beschwerden für Personen mit Diabetes Mellitus Typ 1 und Typ 2 – Ergebnisse einer randomisiert-klinischen Studie nach 12 Monaten.

Nobis, S., Lehr, D., Berking, M., Baumeister, H., Riper, H., Snoek, F. & Ebert, D. D., 2016, In : Diabetologie und Stoffwechsel. 11, S01

Research output: Contribution to JournalArticleAcademicpeer-review