20022019
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Research Output 2002 2019

2019

Aiming for impact: Differential effect of motivational drivers on effort and performance in knowledge valorisation

Van De Burgwal, L. H. M., Hendrikse, R. & Claassen, E., Oct 2019, In : Science and Public Policy. 46, 5, p. 747-762 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
civil society
driver
economics
performance
stakeholder

Dealing with the remaining controversies of probiotic safety

Van Den Nieuwboer, M. & Claassen, E., Jun 2019, In : Beneficial Microbes. 10, 6, p. 605-616 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Probiotics
Safety
Critical Illness
Synbiotics
Health Services Needs and Demand

Policies and patenting to stimulate the biotechnology sector: Evidence from the Netherlands

Van Dongen, P., Tak, H. & Claassen, E., 1 Feb 2019, In : Science and Public Policy. 46, 1, p. 136-147 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

biotechnology
patent
Netherlands
evidence
policy

Probiotics for Childhood Functional Gastrointestinal Disorders: Do We Know What We Advise?

Browne, P. D., de Groen, A. C., Claassen, E. & Benninga, M. A., 1 Dec 2019, In : PharmaNutrition. 10, p. 1-7 7 p., 100160.

Research output: Contribution to JournalArticleAcademicpeer-review

Gastrointestinal Diseases
Probiotics
digestive system diseases
childhood
probiotics

Probiotics for improving quality of life in ulcerative colitis: Exploring the patient perspective

van der Waal, M. B., Flach, J., Browne, P. D., Besseling-van der Vaart, I., Claassen, E. & van de Burgwal, L. H. M., Mar 2019, In : PharmaNutrition. 7, p. 1-14 14 p., 100139.

Research output: Contribution to JournalArticleAcademicpeer-review

colitis
Probiotics
quality of life
Ulcerative Colitis
probiotics

Probiotics in pregnancy: Protocol of a double-blind randomized controlled pilot trial for pregnant women with depression and anxiety (PIP pilot trial)

Browne, P. D., Bolte, A., Claassen, E. & De Weerth, C., 17 Jul 2019, In : Trials. 20, p. 1-21 21 p., 440.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Probiotics
Pregnant Women
Anxiety
Randomized Controlled Trials
Mothers

The Nagoya Protocol on Access to Genetic Resources and Benefit Sharing: Best practices for users of Lactic Acid Bacteria

Flach, J., dos S. Ribeiro, C., van der Waal, M. B., van der Waal, R. X., Claassen, E. & van de Burgwal, L. H. M., Sep 2019, In : PharmaNutrition. 9, p. 1-6 6 p., 100158.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
genetic resources
Practice Guidelines
lactic acid bacteria
Lactic Acid
Bacteria

Towards a rational design of faecal transplant analogues

Larsen, O. F. A., Koning, A. H. J., van der Spek, P. J. & Claassen, E., 3 Apr 2019, In : Scientific Reports. 9, p. 1-6 6 p., 5558.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Safety
Microbiota
Costs and Cost Analysis
Therapeutics
Fecal Microbiota Transplantation
2018
Open Access
product development
Microbiota
Probiotics
Industry
Public-Private Sector Partnerships

A research agenda to reinforce rabies control: A qualitative and quantitative prioritization

Neevel, A. M. G., Hemrika, T., Claassen, E. & van de Burgwal, L. H. M., 4 May 2018, In : PLoS Neglected Tropical Diseases. 12, 5, e0006387.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Rabies
Research
Mass Vaccination
Rabies Vaccines
Rabies virus

Economic potential of probiotic supplementation in institutionalized elderly with chronic constipation

Flach, J., Koks, M., van der Waal, M. B., Claassen, E. & Larsen, O. F. A., Dec 2018, In : PharmaNutrition. 6, 4, p. 198-206 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
constipation
Probiotics
Constipation
probiotics
nursing homes

How academic patents shape innovations: A study into factors that determine the use of patents in pathways of research commercialisation

van Dongen, P. H., 2018, 174 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File

How ownership rights over microorganisms affect infectious disease control and innovation: A root-cause analysis of barriers to data sharing as experienced by key stakeholders

Ribeiro, C. D. S., van Roode, M. Y., Haringhuizen, G. B., Koopmans, M. P., Claassen, E. & van de Burgwal, L. H. M., 2 May 2018, In : PLoS ONE. 13, 5, e0195885.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Root Cause Analysis
Disease control
Information Dissemination
Ownership
ownership

Hybrid business models for ‘Organ-on-a-Chip’ technology: The best of both worlds

van de Burgwal, L. H. M., van Dorst, P., Viëtor, H., Luttge, R. & Claassen, E., Jun 2018, In : PharmaNutrition. 6, 2, p. 55-63 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Technology
translation (genetics)
laboratory equipment
human physiology
Equipment and Supplies
Open Access
innovation
ecosystem
information technology
occupation
stakeholder

On the societal impact of knowledge: Understanding knowledge valorisation in the life sciences

van de Burgwal, L. H. M., 2018, 341 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File

Probiotic research priorities for the healthy adult population: A review on the health benefits of Lactobacillus rhamnosus GG and Bifidobacterium animalis subspecies lactis BB-12

Flach, J., van der Waal, M. B., Kardinaal, A. F. M., Schloesser, J., Ruijschop, R. M. A. J. & Claassen, E., 16 Mar 2018, In : Cogent Food & Agriculture. 4, p. 1-30 30 p., 1452839.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Lactobacillus rhamnosus
Probiotics
Insurance Benefits
Research
Population

The underexposed role of food matrices in probiotic products: Reviewing the relationship between carrier matrices and product parameters

Flach, J., van der Waal, M. B., van den Nieuwboer, M., Claassen, E. & Larsen, O. F. A., 13 Oct 2018, In : Critical Reviews in Food Science and Nutrition. 58, 15, p. 2570-2584 15 p.

Research output: Contribution to JournalReview articleAcademicpeer-review

food matrix
Probiotics
probiotics
Food
gastrointestinal system
Open Access
Vaccines
vaccines
stakeholders
markets
Public-Private Sector Partnerships
2017

Analysing patent terms and citations to determine the value of gene therapies

van Dongen, P., El Hejazi, Z. N. & Claassen, H. J. H. M., 1 Apr 2017, In : Journal of Commercial Biotechnology. 23, 2, p. 61-73 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Gene therapy
Genetic Therapy
Patents
Biological Science Disciplines
Cluster analysis

Barriers to innovation in human rabies prophylaxis and treatment: A causal analysis of insights from key opinion leaders and literature.

van de Burgwal, L. H. M., Neevel, A. M. G., Pittens, C. A. C. M., Osterhaus, A. D. M. E., Rupprecht, C. E. & Claassen, H. J. H. M., 1 Dec 2017, In : Zoonoses and Public Health. 64, 8, p. 599-611 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Challenges and best practices for big data-driven healthcare innovations conducted by profit–non-profit partnerships – a quantitative prioritization

Witjas-Paalberends, E. R., van Laarhoven, L. P. M., van de Burgwal, L. H. M., Feilzer, J., de Swart, J., Claassen, H. J. H. M. & Jansen, W. T. M., 6 Sep 2017, In : International Journal of Healthcare Management. p. 1-11 11 p., http://dx.doi.org/10.1080/20479700.2017.1371367.

Research output: Contribution to JournalArticleAcademicpeer-review

Public-Private Sector Partnerships
Practice Guidelines
Delivery of Health Care
Politics
Information Dissemination

Incentives for knowledge valorisation: a European benchmark

van de Burgwal, L. HM., Dias, A. & Claassen, H. J. H. M., Jun 2017, In : The Journal of Technology Transfer. p. 1-20 20 p., DOI: 10.1007/s10961-017-9594-8.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Bandwidth
Economics
Incentives
Benchmark
Industry

Infant and child microbiota: current status and directions for future research

Browne, P. D., van der Waal, M. B. & Claassen, E., 14 Jul 2017, Microbiota in health and disease: from pregnancy to childhood. Browne, P. D., Claassen, E. & Cabana, M. D. (eds.). Wageningen Academic Publishers, p. 17-35 19 p.

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

Open Access
Microbiota
Dysbiosis
Pediatrics
Health
Research

Medical doctors’ perceptions on probiotics: Lack of efficacy data hampers innovation

Flach, J., Dias, A. S. M., Rademaker, S. H. M., van der Waal, M. B., Claassen, E. & Larsen, O. F. A., 27 Jun 2017, In : PharmaNutrition. 2017, 5, p. 103-108 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Probiotics
physicians
probiotics
general practitioners
General Practitioners

Microbiota in health and disease: from pregnancy to childhood

Claassen, H. J. H. M. (ed.), Browne, P. D. (ed.) & Cabana, M. (ed.), 2017, Wageningen Academic Publishers. 344 p.

Research output: Book / ReportBook editingAcademic

Microbiota
Pregnancy
Dysbiosis
Health
Infant Behavior

Probiotics for healthy ageing: Innovation barriers and opportunities for bowel habit improvement in nursing homes

Larsen, O. F. A., van den Nieuwboer, M., Koks, M., Flach, J. & Claassen, H. J. H. M., 2017, In : Agro FOOD Industry Hi Tech. 28, 5, p. 12-15 4 p.

Research output: Contribution to JournalArticleAcademicpeer-review

nursing homes
Nursing
Probiotics
Nursing Homes
probiotics

Safety of probiotics in infants and children

van den Nieuwboer, M., Browne, P. D. & Claassen, H. J. H. M., 2017, Microbiota in health and disease: from pregnancy to childhood. p. 313-340

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

The mechanistic link between health and gut microbiota diversity

Claassen, H. J. H. M. & Larsen, O. F. A., 2017, (Accepted/In press) In : Scientific Reports. 8, p. 1-5 5 p., 2183.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Health
Microbiota
Health Status
Ecosystem
Gastrointestinal Microbiome

The moderating role of absorptive capacity and the differential effects of acquisitions and alliances on Big Pharma firms' innovation performance

Fernald, K. D. S., Pennings, H. P. G., van den Bosch, J. F., Commandeur, H. R. & Claassen, H. J. H. M., 23 Feb 2017, In : PLoS ONE. 12, 2, p. e0172488

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Innovation
Biotechnology
Pharmaceutical Preparations
Industry
new drugs

The relationships between university IP regimes, scientists’ motivations and their engagement with research commercialisation in Europe

van Dongen, P., Yegros, A., Tijssen, R. & Claassen, H. J. H. M., 2017, In : European Journal of Law and Technology. 8, 2, p. 1-22 22 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
commercialization
regime
university
spin-off
technology transfer
2016
Open Access
vaccines
markets
new markets
genetic engineering
interviews

Disruptive Innovation by Genetic Modification Technology as a Market Driver to Target Unmet Vaccine Needs: Influenza in the Limelight

Ramezanpour, B., 2016

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File
Influenza Vaccines
Technology

Lactobacillus plantarum WCFS1 and its host interaction: a dozen years after the genome

van den Nieuwboer, M., van Hemert, S., Claassen, E. & de vos, W., Jul 2016, In : Microbial Biotechnology. 9, 4, p. 452-65 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Lactobacillus plantarum
Immune system
Genes
Health
Genome

Self-Centric and Altruistic Unmet Needs for Ebola: Barriers to International Preparedness

Van de Burgwal, L. H. M., Reperant, L. A., Osterhaus, A. D. M. E., Iancu, S. C., Pronker, E. S. & Claassen, H. J. H. M., 20 Jun 2016, In : Disaster medicine and public health preparedness. 10, 4, p. 644-8 5 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Bioterrorism
Disease Outbreaks
Active Immunotherapy
Disasters
Chi-Square Distribution

Vector-based genetically modified vaccines: Exploiting Jenner's legacy

Ramezanpour, B., Haan, I., Osterhaus, A. & Claassen, E., 7 Dec 2016, In : Vaccine. 34, 50, p. 6436-6448 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Vaccines
vaccines
genetic engineering
vaccine development
Poxviridae

Venturing across the Atlantic

Rooswinkel, R. W., Berbers, D. S. W., Claassen, E. H. J. H. M. & van Deventer, S., 8 Nov 2016, In : Nature Biotechnology. 34, 11, p. 1095-1098 4 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2015

An exploration of the creation and flow of knowledge involving universities

Davey, T. A., Claassen, H. J. H. M. & van de Burgwal, L. H. M., 26 Jun 2015, UIIN International Conference.

Research output: Chapter in Book / Report / Conference proceedingConference contributionAcademicpeer-review

An interdisciplinairy analysis of genetically modified vaccines: from clinical trials to market.

Ramezanpour, B., Riemens, T., van de Burgwal, L. H. M. & Claassen, E., 2015, In : International Journal of Clinical Trials. 2, 4, p. 64-74

Research output: Contribution to JournalArticleAcademicpeer-review

A quantitative key-opinion-leader analysis of innovation barriers in probiotic research and development: valorisation and improving the tech transfer cycle

van den Nieuwboer, M., van de Burgwal, L. H. M. & Claassen, E., 2015, In : PharmaNutrition. 4, 1, p. 9-18 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Probiotics
research and development
probiotics
Research
Root Cause Analysis

Biotechnology Commercialization Strategies: Risk and Return in Interfirm Cooperation

Fernald, K. D. S., Pennings, H. P. G. & Claassen, E., Nov 2015, In : Journal of Product Innovation Management. 32, 6, p. 971-996 26 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Biotechnology
Innovation
Industry
Mergers and acquisitions
Product development

Cost-effectiveness in Clostridium difficile treatment decision-making.

Nuijten, M. J., Keller, J. J., Visser, C. E., Redekop, K., Claassen, E., Speelman, P. & Pronk, M. H., 2015, In : World journal of clinical cases. 3, 11, p. 935-941

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Improving the bowel habits of elderly residents in a nursing home using probiotic fermented milk

van den Nieuwboer, M., Klomp-Hogeterp, A., Verdoorn, S., Metsemaker-Brameijer, L., Vriend, T. M., Claassen, E. & Larsen, O. F. A., 2015, In : Beneficial Microbes. 6, p. 397-403

Research output: Contribution to JournalArticleAcademicpeer-review

Probiotics
Nursing Homes
Lactobacillus casei
Habits
Milk

Innovation Drivers in Microbiota R&D

van den Nieuwboer, M., 2015, Den Bosch: Uitgeverij BoxPress. 227 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File

Market implementation of the MVA platform for pre-pandemic and pandemic influenza vaccines: A quantitative key opinion leader analysis.

Ramezanpour, B., Pronker, E. S., Kreijtz, J. H. C. M., Osterhaus, A. D. M. E. & Claassen, E., 2015, In : Vaccine. 33, 35, p. 3349-3358

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Vaccinia virus
Influenza Vaccines
Pandemics
pandemic
influenza

Patient needs and research priorities in probiotics: A quantitative KOL prioritization analysis with emphasis on infants and children

van den Nieuwboer, M., Browne, P. D. & Claassen, E., 2015, In : PharmaNutrition. 4, 1, p. 19-28 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

prioritization
Probiotics
probiotics
Diarrhea
diarrhea

Safety of probiotics and synbiotics in children under 18 years of age.

van den Nieuwboer, M., Brummer, R. J., Guarnar, F., Morelli, L., Cabana, M. & Claassen, E., 2015, In : Beneficial Microbes. 6, 5, p. 615-630

Research output: Contribution to JournalArticleAcademicpeer-review

Synbiotics
Probiotics
Safety
Terminology
Population

Scratching the surface: Exploratory analysis of key opinion leaders on rate limiting factors in novel adjuvanted-vaccine

Pronker, E. S., Claassen, E., Weenen, T., Commandeur, H. & Osterhaus, A. D. M. E., 2015, In : Technological Forecasting and Social Change. 90, B, p. 420-432

Research output: Contribution to JournalArticleAcademicpeer-review

Vaccines
Conflict of Interest
Risk Management
Public health
Risk management

Trade-sale exits in different biotech sectors

Fernald, K. D. S. & Claassen, E., 2015, In : Nature Biotechnology. 33, p. 1221-1239

Research output: Contribution to JournalArticleAcademicpeer-review

Venture capitalists as gatekeepers for biotechnological innovation

Fernald, K., Hoeben, R. & Claassen, H. J. H. M., 1 Jul 2015, In : Journal of Commercial Biotechnology. 21, 3, p. 32-41 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Innovation
Technology
Sales
Precision Medicine
Oncology