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Research Output 1997 2019

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Chapter
2018

A Structural Framework for GPCR Chemogenomics: What’s In a Residue Number?

Vass, M., Kooistra, A. J., Verhoeven, S., Gloriam, D., de Esch, I. J. P. & de Graaf, C., 2018, Computational Methods for GPCR Drug Discovery. Heifetz, A. (ed.). Humana Press Inc, p. 73-113 41 p. (Methods in Molecular Biology; vol. 1705).

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

G-Protein-Coupled Receptors
Binding Sites
Ligands
Workflow
Mutation
2017

1.15 - Structural Chemogenomics Databases to Navigate Protein–Ligand Interaction Space

Kanev, G. K., Kooistra, A. J., de Esch, I. J. P. & de Graaf, C., 2017, 1.15 - Structural Chemogenomics Databases to Navigate Protein–Ligand Interaction Space. Comprehensive Medicinal Chemistry III ed. Elsvier, Vol. 1. p. 444-471

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

Ligands
Proteins
Drug Combinations
Proteome
Bioactivity
2014

From three-dimensional GPCR structure to rational ligand discovery

Kooistra, A. J., Leurs, R., De Esch, I. J. P. & de Graaf, C., 2014, G Protein-Coupled Receptors - Modeling and Simulation. Filizola, M. (ed.). Springer New York LLC, p. 129-157 29 p. (Advances in Experimental Medicine and Biology; vol. 796).

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

Ligands
Screening
Workflow
Structural Models
G-Protein-Coupled Receptors