I.J.P. de Esch

prof. dr.

19972019
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Research Output 1997 2019

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PhD Thesis - Research VU, graduation VU
2018

Design and synthesis of tool compounds to probe GPCRs

Kuhne, S., 2018, 248 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File
2015

In silico Medicinal Chemistry: Investigating GPCRs: key regulators of signal transduction and cell function

Kooistra, A. J., 2015

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File
Pharmaceutical Chemistry
Computer Simulation
Signal Transduction

Trypanosoma brucei phosphodiesterase B1 as a drug target for Human African Trypanosomiasis

Jansen, C. J. W., 2015

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File
African Trypanosomiasis
Pharmaceutical Preparations
Trypanosoma brucei PDEB1 protein
2013

Computational Medicinal Chemistry in Drug Discovery

Schultes, S., 2013

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File

Design and Preparation of New Ligands Interacting with the Histamine H4 Receptor

Engelhardt, H., 2013, 208 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File

Fragment-based drug design of small molecule EPHA4 kinase inhibitors

van Linden, O. P. J., 2013

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File
2012

Computational Studies of the Histamine H4 Receptor-Ligand Interactions

Istyastono, E. P., 2012

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File

Fragment-based drug discovery approaches towards novel 5-HT3 receptor ligands

Verheij, M. H. P., 2012

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File
2011

Exploring fragment space: Library construction, screening and fragment growing

de Kloe, G. E., 2011

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File

Structure-based design of AChBP ligands, new insights and applications

Edink, E. S., 2011

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File
2010

Design, synthesis and pharmacological evaluation of non-peptidergic ligands for the human CXCR3 receptor

Storelli, S., 2010

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File

The acetylcholine binding protein as a template for the ligand binding domains of the homologous nicotinic receptors

Akdemir, A., 2010, 201 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File
2009

Design and Synthesis of New Histamine H4 Receptor Ligands

Smits, R. A., 2009

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File
2007

Design and synthesis of small nonpeptidergic ligands for the human cytomegalovirus-encoded receptor US28

Hulshof, J. W., 2007

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File
2000

Synthesis, structure activity relationships and molecular modelling of histamine H3 receptor ligands

de Esch, I. J. P., 2000

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File