20112018
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Fingerprint Dive into the research topics where J. Wortel is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 9 Similar Profiles
Physiology Chemical Compounds
Synapses Medicine & Life Sciences
Proteomics Medicine & Life Sciences
Eukaryotic Initiation Factor-2B Medicine & Life Sciences
Fragile X Syndrome Medicine & Life Sciences
Inbred DBA Mouse Medicine & Life Sciences
Pyramidal Cells Medicine & Life Sciences
Astrocytes Medicine & Life Sciences

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Research Output 2011 2018

Adult mouse eIF2Bϵ Arg191His astrocytes display a normal integrated stress response in vitro

Wisse, L. E., Ter Braak, T. J., Van De Beek, M. C., Van Berkel, C. G. M., Wortel, J., Heine, V. M., Proud, C. G., Van Der Knaap, M. S. & Abbink, T. E. M., 28 Feb 2018, In : Scientific Reports. 8, 1, p. 1-9 9 p., 3773.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Eukaryotic Initiation Factor-2B
Astrocytes
Mutation
White Matter
In Vitro Techniques

Astrocytes are central in the pathomechanisms of vanishing white matter

Dooves, S., Bugiani, M., Postma, N. L., Polder, E., Land, N., Horan, S. T., van Deijk, A. L. F., van de Kreeke, A., Jacobs, J. G., Vuong, C., Klooster, J., Kamermans, M., Wortel, J., Loos, M., Wisse, L. E., Scheper, G. C., Abbink, G. E. M., Heine, V. M. & Knaap, M., 2016, In : Journal of Clinical Investigation. 126, p. 1512-1524 4.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Strain Differences in Presynaptic Function: Proteomics, Ultrastructure, and Physiology of Hippocampal Synapses in DBA/2J AND C57Bl/6J mice..

Lenselink, A. M., Rotaru-Marcu, D. C., Li, K. W., van Nierop, P., Rao-Ruiz, P., Loos, M., van der Schors, R. C., Gouwenberg, Y., Wortel, J., Mansvelder, H. D., Smit, A. B. & Spijker, S., 2015, In : Journal of Biological Chemistry. 290, 25, p. 15635-15645

Research output: Contribution to JournalArticleAcademicpeer-review

Inbred DBA Mouse
Physiology
Proteomics
Synapses
rab3A GTP-Binding Protein

Development of dendritic tonic GABAergic inhibition regulates excitability and plasticity in CA1 pyramidal neurons.

Groen, M. R., Paulsen, O., Pérez-Garci, E., Nevian, T., Wortel, J., Dekker, M. P., Mansvelder, H. D., van Ooijen, A. & Meredith, R. M., 2014, In : Journal of Neurophysiology. 112, 2, p. 287-299

Research output: Contribution to JournalArticleAcademicpeer-review

Pyramidal Cells
Action Potentials
Neurons
Dendrites
Neuronal Plasticity

Proteomics, ultrastructure, and physiology of hippocampal synapses in a fragile X syndrome mouse model reveal presynaptic phenotype

Klemmer, P., Meredith, R. M., Holmgren, C. D., Klychnikov, O. I., Stahl-Zeng, J., Loos, M., van der Schors, R. C., Wortel, J., de Wit, H., Spijker, S., Rotaru, D. C., Mansvelder, H. D., Smit, A. B. & Li, K. W., 2011, In : Journal of Biological Chemistry. 286, 29, p. 25495-25504 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Fragile X Syndrome
Physiology
Proteomics
Synapses
Phenotype