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Dr. Jessica Legradi works as an assistant Professor at the department Environment and Health. She teaches toxicology at BSc and MSc level at the VU. Her research focuses on studying the toxicological effects of environmental contaminants using zebrafish embryos (Danio rerio). She identifies mechanisms of toxicity of environmental pollutants and develops new specific bioassays also applicable for chemical toxicity screening. Within several European projects she characterized the toxic potential and identified the mechanisms of toxicity of different chemicals found in the environment. Therefore she applied and adapted state of the art genomics, proteomics and metabolomics technologies. Moreover, she worked on biological test systems that can guide contaminant detection in complex environmental samples by combining bioassays with analytical chemical analysis methods (EDA). During the last years she developed a strong interest for  behavioural testing and neurotoxicity.

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Research Output 2007 2018

Combining ex-ante LCA and EHS screening to assist green design: A case study of cellulose nanocrystal foam

Tan, L., Mandley, S. J., Peijnenburg, W., Waaijers-van der Loop, S. L., Giesen, D., Legradi, J. B. & Shen, L. 3 Jan 2018 In : Journal of Cleaner Production. 178, p. 494-506 13 p.

Research output: Contribution to journalArticle

Open Access

Bisphenol A alternatives in thermal paper from the Netherlands, Spain, Sweden and Norway. Screening and potential toxicity

Björnsdotter, M. K., Jonker, W., Legradi, J., Kool, J. & Ballesteros-Gómez, A. 1 Dec 2017 In : Science of the Total Environment. 601-602, p. 210-221 12 p.

Research output: Contribution to journalArticle

Open Access

Enhanced uptake of BPA in the presence of nanoplastics can lead to neurotoxic effects in adult zebrafish

Chen, Q., Yin, D., Jia, Y., Schiwy, S., Legradi, J., Yang, S. & Hollert, H. 7 Aug 2017 In : Science of the Total Environment. 609, dec 2017, p. 1312-1321 10 p.

Research output: Contribution to journalArticle