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Last mutation Ancillary Activities: Amsterdam(2011-04-26)

Personal information

Dr. Jessica Legradi works as an assistant Professor at the department Environment and Healthy. She teaches toxicology at BSc and MSc level at the VU. Her research focuses on studying the toxicological effects of environmental contaminants using zebrafish embryos (Danio rerio). She identifies mechanisms of toxicity of environmental pollutants and develops new specific bioassays also applicable for chemical toxicity screening. Within several European projects she characterized the toxic potential and identified the mechanisms of toxicity of different chemicals found in the environment. Therefore she applied and adapted state of the art genomics, proteomics and metabolomics technologies. Moreover, she worked on biological test systems that can guide contaminant detection in complex environmental samples by combining bioassays with analytical chemical analysis methods (EDA). During the last years she developed a strong interest for  behavioural testing and neurotoxicity.

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Research Output 2007 2017

Bisphenol A alternatives in thermal paper from the Netherlands, Spain, Sweden and Norway. Screening and potential toxicity

Björnsdotter, M. K., Jonker, W., Legradi, J., Kool, J. & Ballesteros-Gómez, A. 1 Dec 2017 In : Science of the Total Environment. 601-602, p. 210-221 12 p.

Research output: Scientific - peer-reviewArticle

Determination of monoamine neurotransmitters in zebrafish (Danio rerio) by gas chromatography coupled to mass spectrometry with a two-step derivatization

Aragon, A., Legradi, J. B., Ballesteros-Gómez, A., Legler, J., van Velzen, M., de Boer, J. & Leonards, P. 2017 In : Analytical and Bioanalytical Chemistry.

Research output: Scientific - peer-reviewArticle

Fishing for contaminants: identification of three mechanism specific transcriptome signatures using Danio rerio embryos

Hausen, J., Otte, J. C., Legradi, J., Yang, L., Strähle, U., Fenske, M., Hecker, M., Tang, S., Hammers-Wirtz, M., Hollert, H., Keiter, S. H. & Ottermanns, R. 8 Apr 2017 In : Environmental Science and Pollution Research International. p. 1-14 14 p.

Research output: Scientific - peer-reviewArticle