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Research Output 1987 2018

  • 43 Article
  • 3 PhD Thesis - Research VU, graduation VU

Drug induced liver injury: assessment of inter-individual variation in the balance of bioactivation and inactivation as risk factor

den Braver, M. W. 2018 288 p.

Research output: ThesisPhD Thesis - Research VU, graduation VU

Open Access
File

Inter-individual variability in activity of the major drug metabolizing enzymes in liver homogenates of 20 Individuals

Vos, J. C., den Braver-Sewradj, S. P., den Braver, M. W., van Dijk, M., Zhang, Y., Dekker, S. J., Wijaya, L., Vermeulen, N. P. E., Richert, L. & Commandeur, J. N. M. 8 Jan 2018 In : Current Drug Metabolism.

Research output: Contribution to journalArticle

Inter-individual variation in hepatic drug metabolism: The potential of in vitro assays in unraveling the role of metabolism in drug induced liver toxicity

den Braver-Sewradj, S. P. 2018 252 p.

Research output: ThesisPhD Thesis - Research VU, graduation VU

Open Access
File

Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations

den Braver-Sewradj, S. P., den Braver, M. W., Toorneman, R. M., van Leeuwen, S., Zhang, Y., Dekker, S. J., Vermeulen, N. P. E., Commandeur, J. N. M. & Vos, J. C. 19 Feb 2018 In : Chemical Research in Toxicology. 31, 2, p. 116-126 11 p.

Research output: Contribution to journalArticle