Personal profile

Teaching

Bachelorcourses:

Basisprakticum Farmacochemie (coordinator)

Farmacokinetiek en ADME-processen (lecturer)

Bioanalyse en Farmaceutische Toxicologie (lecturer)

Prakticum Moleculaire Toxicologie (coordinator)

Bachelorprojecten Moleculaire Toxicologie (coordinator)

 

Mastercourses:

ADMET (coordinator/lecturer)

Drug-Induced Stress and Cellular Responses (coordinator/lecturer)

 

Postgraduate courses:

PET-module Molecular Toxicology  (coordinator/lecturer)

Safescimet-module: Biochemical and Molecular Toxicologie  (coordinator/lecturer)

Research

Role of biotransformation in chemically-induced toxicity.  Consequences of genetic polymorphisms of bioactivating (P450's) and bioinactivating (GST's, NQO's) enzymes for susceptibility to drug-induced toxicity.

Ancillary activities

Board of section Pharmaceutical Toxicology of the Dutch Society of Toxicology (NVT)

Member Commissie van Toezicht of programme of Postgratuate Education in Toxicology

Ancillary activities

No ancillary activities

Ancillary activities are updated daily

Education/Academic qualification

Molecular Toxicology, PhD, Vrije Universiteit Amsterdam

Farmacochemie, Master, Vrije Universiteit Amsterdam

Scheikunde, Bachelor, Vrije Universiteit Amsterdam

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Research Output 1987 2018

Drug induced liver injury: assessment of inter-individual variation in the balance of bioactivation and inactivation as risk factor

den Braver, M. W. 2018 288 p.

Research output: ThesisPhD Thesis - Research VU, graduation VU

Open Access
File

Effect of UGT2B7*2 and CYP2C8*4 polymorphisms on diclofenac metabolism

Lazarska, K. E., Dekker, S. J., Vermeulen, N. P. E. & Commandeur, J. N. M. 1 Mar 2018 In : Toxicology Letters. 284, 1 March, p. 70-78 9 p.

Research output: Contribution to journalArticle