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Personal profile



Basisprakticum Farmacochemie (coordinator)

Farmacokinetiek en ADME-processen (lecturer)

Bioanalyse en Farmaceutische Toxicologie (lecturer)

Prakticum Moleculaire Toxicologie (coordinator)

Bachelorprojecten Moleculaire Toxicologie (coordinator)



ADMET (coordinator/lecturer)

Drug-Induced Stress and Cellular Responses (coordinator/lecturer)


Postgraduate courses:

PET-module Molecular Toxicology  (coordinator/lecturer)

Safescimet-module: Biochemical and Molecular Toxicologie  (coordinator/lecturer)


Role of biotransformation in chemically-induced toxicity.  Consequences of genetic polymorphisms of bioactivating (P450's) and bioinactivating (GST's, NQO's) enzymes for susceptibility to drug-induced toxicity.

Ancillary activities

Board of section Pharmaceutical Toxicology of the Dutch Society of Toxicology (NVT)

Member Commissie van Toezicht of programme of Postgratuate Education in Toxicology

Ancillary activities

No ancillary activities

Ancillary activities are updated daily

Education/Academic qualification

Molecular Toxicology, PhD, Vrije Universiteit Amsterdam

Farmacochemie, Master, Vrije Universiteit Amsterdam

Scheikunde, Bachelor, Vrije Universiteit Amsterdam

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1987 2019

Cytochrome P-450 CYP3A

A combined computational and experimental study on selective flucloxacillin hydroxylation by cytochrome P450 BM3 variants

Luirink, R. A., Dekker, S. J., Capoferri, L., Kuiper, C. L., Janssen, L. F. H., Ari, M. E., Vermeulen, N. P. E., Vos, J. C., Commandeur, J. N. M. & Geerke, D. P., Jul 2018, In : Journal of Inorganic Biochemistry. 184, p. 115-122 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Cytochrome P-450 Enzyme System
Open Access

Drug induced liver injury: assessment of inter-individual variation in the balance of bioactivation and inactivation as risk factor

den Braver, M. W., 2018, 288 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access

Activities 1997 1999

  • 6 Lecture / Presentation

Cytochrome P450 in Drug Research: enzymology

Commandeur, J. N. M. (Speaker)

Activity: Lecture / PresentationAcademic

Cytochrome P450 in Drug Research: practical aspects.

Commandeur, J. N. M. (Speaker)

Activity: Lecture / PresentationAcademic

Chemical reactivity and selectivity of reactive intermediates.

Commandeur, J. N. M. (Speaker)
26 Aug 1997

Activity: Lecture / PresentationAcademic

Enzymology of Cytochrome P450.

Commandeur, J. N. M. (Speaker)
24 Aug 1997

Activity: Lecture / PresentationAcademic

Enzymology of glutathione S-transferases.

Commandeur, J. N. M. (Speaker)
24 Aug 1997

Activity: Lecture / PresentationAcademic