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Personal information

Dr. Joen Luirink completed his PhD thesis on Structure and function of the pCloDF13 encoded Bacteriocin Release Protein at VU University Amsterdam in 1989. Thereafter, he became associate professor in the Molecular Microbiology research group, developing his own research line on Molecular cell biology of pro- and eukaryotes. In 1991 and 1992, Luirink worked as a visiting scientist in the Cell Biology Program in Heidelberg (Germany) with professor B. Dobberstein.

Since 2008, he is consultant and member of the advisory board of Xbrane Bioscience. In 2013, he became Chief Scientific Officer of Abera Bioscience, a Stockholm based biotechnology company focused on developing innovative vaccines and vaccine development technologies. Luirink’s research interests lie in protein trafficking in (pathogenic) bacteria, biogenesis of membrane proteins, bacterial protein production platforms and vaccine development.

Ancillary activities

  • XBrane Bioscience AB | Stockholm | Scientific Adviser | 2018-01-20
  • Abera Bioscience | Stockholm | CSO | 2018-04-01

Ancillary activities are updated daily

Research

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Research Output 1998 2018

Comparing autotransporter β-domain configurations for their capacity to secrete heterologous proteins to the cell surface

Jong, W. S. P., Schillemans, M., ten Hagen-Jongman, C. M., Luirink, J. & van Ulsen, P., 7 Feb 2018, In : PLoS ONE. 13, 2, e0191622

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
IgA-specific serine endopeptidase
recombinant proteins
Membrane Proteins
Recombinant Proteins
Membranes

Display of recombinant proteins on bacterial outer membrane vesicles by using protein ligation

van den Berg van Saparoea, H. B., Houben, D., de Jonge, M. I., Jong, W. S. P. & Luirink, J., Apr 2018, In : Applied and Environmental Microbiology. 84, 8, p. 1-17 17 p., e02567-17

Research output: Contribution to JournalArticleAcademicpeer-review

hemoglobin
vesicle
Recombinant Proteins
recombinant proteins
Ligation

Immunization with Skp delivered on outer membrane vesicles protects mice against enterotoxigenic Escherichia coli CHALLENGE

Hays, M. P., Houben, D., Yang, Y., Luirink, J. & Hardwidge, P. R., 1 May 2018, In : Frontiers in Cellular and Infection Microbiology. 8, MAY, 132

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Enterotoxigenic Escherichia coli
Immunization
Glutathione Transferase
Membranes
Antigens

On display: Autotransporter secretion and application

Van Ulsen, P., Zinner, K. M., Jong, W. S. P. & Luirink, J., 1 Sep 2018, In : FEMS Microbiology Letters. 365, 18, p. 1-10 10 p., fny165

Research output: Contribution to JournalReview articleAcademicpeer-review

Membranes
Proteins
Secretory Pathway
Virulence Factors
Gram-Negative Bacteria

Structural analysis of the interaction between the bacterial cell division proteins FTSQ and FTSB

Kureisaite-Ciziene, D., Varadajan, A., McLaughlin, S. H., Glas, M., Silva, A. M., Luirink, R., Mueller, C., Blaauwen, T. D., Grossmann, T. N., Luirink, J. & Löwe, J., 11 Sep 2018, In : mBio. 9, 5, p. 1-17 17 p., e01346-18

Research output: Contribution to JournalArticleAcademicpeer-review

Cell Division
Proteins
Bacteria
Periplasm
Membrane Proteins