1993 …2019
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Research Output 1993 2019

2002

Defective translocation of a signal sequence mutant in a prlA4 suppressor strain of Escherichia coli.

Adams, H., Scottie, P. A., Luirink, S. & Tommassen, J., 2002, In : European Journal of Biochemistry. 269, p. 5572-5580 8 p.

Research output: Contribution to JournalArticleAcademic

Signal Recognition Particle
Protein Sorting Signals
Escherichia coli
Membrane Proteins
Endopeptidase K

Escherichia coli hemoglobin protease autotransporter contributes to synergistic abscess formation and heme-dependent growth of Bacteroides fragilis.

Otto, B. R., van Dooren, S. J. M., Dozois, C. M., Luirink, S. & Oudega, B., 2002, In : Infection and Immunity. 70, p. 5-10 5 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Bacteroides fragilis
Heme
Abscess
Intraabdominal Infections
Hemoglobins

Targeting, isertion and localization of E. coli YidC.

Urbanus, M. L., Froderberg, L., Drew, D., Bjork, P., de Gier, J-W., Brunner, J., Oudega, B. & Luirink, S., 2002, In : Journal of Biological Chemistry. 277, p. 12718-12723 5 p.

Research output: Contribution to JournalArticleAcademic

Open Access
File
Escherichia coli
Membrane Proteins
Signal Recognition Particle
Poles
Membranes

The presence of a helix breaker in the hydrophobic core of signal sequences of secretory proteins prevents recognition by the signal-recognition particle in Escherichia coli.

Adams, H., Scottie, P. A., Cock, H., Luirink, S. & Tommassen, J., 2002, In : European Journal of Biochemistry. 269, p. 5564-5571 7 p.

Research output: Contribution to JournalArticleAcademic

Signal Recognition Particle
Protein Sorting Signals
Glycine
Escherichia coli
Membrane Proteins

YidC and SecY mediate membrane insertion of a Type I transmembrane domain.

Houben, E. N. G., Urbanus, M. L., Van der laan, M., ten Hagen-Jongman ten, C. M., Driessen, A. J. M., Brunner, J., Oudega, B. & Luirink, S., 2002, In : Journal of Biological Chemistry. 277, p. 35880-35886 6 p.

Research output: Contribution to JournalArticleAcademic

Open Access
File
Membrane Proteins
Membranes
Escherichia coli
Lipids
Ribosomes
2001

Biogenesis of inner membrane proteins in Escherichia coli

de Gier, J-W. & Luirink, S., 2001, In : Molecular Microbiology. 40, p. 314-322 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Membrane Proteins
Escherichia coli
Proteins
Membranes
E coli inner membrane protein

Biosynthesis of K88 fimbriae in Escherichia coli: interaction of tip-subunit FaeC with the periplasmic chaperone FaeE and the outer membrane usher FaeD.

Mol, O., Oudhuis, W. C., Oud, R. P. C., Sijbrandi, R., Luirink, S., Harms, N. & Oudega, B., 2001, In : Journal of Molecular Microbiology and Biotechnology. 3, p. 135-142 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Chaperones in secretion pathways of Escherichia coli

Harms, N., Luirink, S. & Oudega, B., 2001, Molecular chaperones in the cell (Frontiers in Molecular Biology). Lund, ED. P. A. (ed.). Oxford University press, 25 p.

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

Evidence for coupling of membrane targeting and function of the signal recognition particle (SRP) receptor FtsY.

Herkovits, A. A., Seluanov, A., Rasjbaum, R., ten Hagen, C. M., Henrichs, T., Bochkareva, E. S., Philips, G. J., Probst, F. J., Nakae, T., Ehrmann, M., Luirink, S. & Bibi, E., 2001, In : EMBO Reports. 2, p. 1040-1046 6 p.

Research output: Contribution to JournalArticleAcademic

Membranes
Proteolysis
Escherichia coli
Catalytic Domain
Synchronization

Important role of the tetraloop region of 4,5 S RNA in SRP binding to its receptor FtsY.

Jagath, J. R., Matassova, N. B., de Leeuw, E., Warnecke, J. M., Lentzen, G., Rodina, M. V., Luirink, S. & Wintermeyer, W., 2001, In : RNA. 7, p. 293-301 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Signal Recognition Particle
RNA
Base Pairing
Hydroxyl Radical
Gels

Is Ffh required for export of secretory proteins.

Kim, J., Rusch, S., Luirink, S. & Kendall, D. A., 2001, In : FEBS Letters. 505, p. 245-248 3 p.

Research output: Contribution to JournalArticleAcademic

Signal Recognition Particle
Protein Sorting Signals
Hydrophobicity
Hydrophobic and Hydrophilic Interactions
Membrane Proteins

Purification of the autotransporter protein Hbp of Escherichia coli.

van Dooren, S. J. M., Tame, J. R. H., Luirink, S., Oudega, B. & Otto, B. R., 2001, In : FEMS Microbiology Letters. 205, p. 147-150 3 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Hemoglobins
Peptide Hydrolases
Escherichia coli
Proteins
Heme

Reconstitution of SecYEG-dependent membrane protein insertion: nacent FtsQ interacts with YidC in a SecYEG-dependent manner.

Van der laan, M., Houben, E. N. G., Nouwen, N., Luirink, S. & Driessen, A. J. M., 2001, In : EMBO Reports. 2, p. 519-523 4 p.

Research output: Contribution to JournalArticleAcademic

Sec-dependent membrane insertion: sequentail interaction of nascent FtsQ with SecY and YidC.

Urbanus, M. L., Scottie, P. A., Froderberg, L., Saaf, A., de Gier, J-W., Brunner, J., Samulelson, T., Dalbey, R. E., Oudega, B. & Luirink, S., 2001, In : EMBO Reports. 2, p. 524-529 5 p.

Research output: Contribution to JournalArticleAcademic

The early interaction of the outer membrane protein PhoE with the periplasmic chaperone Skp occurs at the cytoplasmic membrane.

Harms, N., Koningstein, G., Dontje, W., Muller, M., Oudega, B., Luirink, S. & Cock, H., 2001, In : Journal of Biological Chemistry. 276, p. 18804-18811 7 p.

Research output: Contribution to JournalArticleAcademic

Open Access
File
Membrane Proteins
Cell Membrane
Membranes
Proteins
Tetrahydrofolate Dehydrogenase

YidC/Oxalp/ALB3:evolutionary concerved mediators of membrane protein assembly

Luirink, S., Samuelson, T. & de Gier, J-W., 2001, In : FEBS Letters. 501, p. 1-5 4 p.

Research output: Contribution to JournalArticleAcademic

2000

Anionic phospholipids are involed in membrane association of the recognition particle receptor FtsY and stimulate its GTPase activity.

de Leeuw, E. P. H., te Kaat, K., Moser, C., Menestrina, G., Demel, R., Kruyff, B., Oudega, B., Luirink, S. & Sinning, I., 2000, In : EMBO Journal. 19, p. 531-541

Research output: Contribution to JournalArticleAcademicpeer-review

Functional analysis of Escherichia coli FtsY in signal recognition particle mediated protein targeting

de Leeuw, E. P. H., 2000, 141 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Nascent Lep insert into the Escherichia coli inner membrane in the vicinity of YidC, SecA.

Houben, E. N. G., Scotti, P. A., Valent, Q. A., Brunner, J., de Gier, J-W., Oudega, B. & Luirink, S., 2000, In : FEBS Letters. 476, p. 229-233

Research output: Contribution to JournalArticleAcademicpeer-review

Die casting inserts
Escherichia coli
Membranes
Membrane Proteins
Signal Recognition Particle

SecB dependence of an exported protein is a continuum influenced by the charaterisitics of the signal peptide or early mature region.

Kim, J., Luirink, S. & Kendell, D. A., 2000, In : Journal of Bacteriology. 182, p. 4108-4112

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Protein Sorting Signals
Alkaline Phosphatase
Proteins
Escherichia coli

YidC, the E. coli homologue of mitochondrial Oxa 1 p, is a component of the Sec tranlocase

Scotti, P. A., Urbanus, M. L., Brunner, J., de Gier, J-W., von Heyne, G., van der Does, F. E. E., Driessen, A. J. M., Oudega, B. & Luirink, S., 2000, In : EMBO Journal. 19, p. 542-549

Research output: Contribution to JournalArticleAcademicpeer-review

1999

Epitope tagging analysis of the outer membrane folding the molecular usher FaeD involved in K88 fimbriae biosynthesis in Escherichia coli.

Harms, N., Oudhuis, W. C., Eppens, E. A., Koster, M., Luirink, S., Valent, Q. A. & Oudega, B., 1999, In : Journal of Molecular Microbiology and Biotechnology. 1, p. 319-325 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Escherichia coli signal recognition particle: a historical perspective

Valent, Q. A., O'Gorman, E. N. S., Scotti, P. A., Luirink, S. & High, S., 1999, Transport of molecules across microbial membranes.. Broome-Smith, J. K., Baumberg, S., Stirling, C. J. & Ward, F. B. (eds.). Cambridge, UK: Cambridge University Press, p. 169-185

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

Molecular characterization of Escherichia coli FtsE and FtsX.

de Leeuw, E. P. H., Graham, B., Philips, G. J., ten Hagen-Jongman ten, C. M., Oudega, B. & Luirink, S., 1999, In : Molecular Microbiology. 31, p. 983-993 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Membrane Proteins
Salts
Escherichia coli
ATP-Binding Cassette Transporters
Membranes

SecA is not required for SRP-mediated targeting and initial membrane insertion of a nascent inner membrane protein.

Scotti, P. A., Valent, Q. A., Manting, E. H., Urbanus, M. L., Driessen, A. J. M., Oudega, B. & Luirink, S., 1999, In : Journal of Biological Chemistry. 274, p. 29883-29888 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Signal Recognition Particle
Membrane Proteins
Membranes
Guanosine Triphosphate
Ribosomes

SRP-mediated protein targeting in Escherichia coli

Valent, Q. A., 1999, 123 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

The signal recognition particle targeting pathway does not necessarily deliver proteins to the Sec-translocase in Escherichia coli.

Cristobal, S., Scotti, P. A., Luirink, S., von Heyne, G. & de Gier, J-W., 1999, In : Journal of Biological Chemistry. 274, p. 20068-20070 3 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Signal Recognition Particle
Escherichia coli
Membrane Proteins
Proteins
Demonstrations
1998

Characterisation of a haemoglobin protease secreted by pathogenic Escherichia coli.

Otto, B. R., van Dooren, S. J. M., Nuijens, J. H., Luirink, S. & Oudega, B., 1998, In : Journal of Experimental Medicine. 188, p. 1091-1103 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Hemoglobins
Peptide Hydrolases
Escherichia coli
Heme
IgA-specific serine endopeptidase

Differential use of the signal recognition particle translocase targeting pathway for inner membrane protein assembly in Escherichia coli.

de Gier, J-W. L., Scotti, P. A., Saaf, A., Valent, Q. A., Kuhn, A., Luirink, S. & von Heijne, G., 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, p. 14646-14651

Research output: Contribution to JournalArticleAcademicpeer-review

Signal Recognition Particle
Membrane Proteins
Escherichia coli
Protein Sorting Signals
Proteins

The E. coli ERP and SecB targeting pathway converge at the translocon

Valent, Q. A., Scotti, P. A., High, S., de Gier, J-W. L., von Heijne, G., Lentzen, G., Wintermeyer, W., Oudega, B. & Luirink, S., 1998, In : EMBO Journal. 17, p. 2504-2512 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Signal Recognition Particle
Enterprise resource planning
Escherichia coli
Membranes
Proteins
1993

Escherichia coli SecB, SecA, and SecY proteins are required for expression and membrane insertion of the bacteriocin release protein, a small lipoprotein

Oudega, B., Mol, O., Van Ulsen, P., Stegehuis, F., Van der Wal, F. J. & Luirink, J., 1 Jan 1993, In : Journal of Bacteriology. 175, 5, p. 1543-1547 5 p.

Research output: Contribution to JournalComment / Letter to the editorAcademic

Bacteriocins
Lipoproteins
Escherichia coli
Membranes
Protein Precursors