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Research Output 2004 2020

2017

Short communication: Genetic association between schizophrenia and cannabis use

Verweij, C. J. H., Abdellaoui, A., Nivard, M. G., Sainz Cort, A., Ligthart, R. S. L., Draisma, H. H. M., Minica, C. C., International Cannabis Consortium, Willemsen, G., Hottenga, J. J., Boomsma, D. I. & Vink, J. M., 1 Feb 2017, In : Drug and Alcohol Dependence. 171, p. 117-121 5 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Cannabis
Schizophrenia
Communication
Genes
Statistics

Short telomere length is associated with impaired cognitive performance in European ancestry cohorts

Hägg, S., Zhan, Y., Karlsson, R., Gerritsen, L., Ploner, A., Lee, J-S., Broer, L., Deelen, J., Marioni, R. E., Wong, A., Lundquist, A., Zhu, G., Hansell, N. K., Sillanpää, E., Fedko, I. O., Amin, N. A., Beekman, M., Craen, A. J. M., Degerman, S., Harris, S. E. & 26 othersKan, K-J., Martin-Ruiz, C., Montgomery, G. W., Adolfsson, A. N., Reynolds, C. A., Samani, N. J., Suchiman, H. E. D., Viljanen, A., von Zglinicki, T., Wright, M. J., Hottenga, J-J., Boomsma, D. I., Rantanen, T., Kaprio, J. A., Nyholt, D. R., Martin, N. G., Nyberg, L., Adolfsson, R., Kuh, D., Starr, J. M., Deary, I. J., Slagboom, P. E., van Duijn, C. M., Codd, V., Pedersen, N. L. & NeuroCHARGE Cognitive Working Group, 18 Apr 2017, In : Translational Psychiatry. 7, 4, p. e1100

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Telomere
Confidence Intervals
Cognition
Random Allocation
Meta-Analysis

Smoking and caffeine consumption: a genetic analysis of their association

Treur, J. L., Taylor, A. E., Ware, J. J., Nivard, M. G., Neale, M. C., McMahon, G., Hottenga, J. J., Baselmans, B. M. L., Boomsma, D. I., Munafò, M. & Vink, J. M., 1 Jul 2017, In : Addiction Biology. 22, 4, p. 1090-1102

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Caffeine
Smoking
Coffee
Netherlands
Mendelian Randomization Analysis

The International Cannabis Consortium: What Did We Learn About The Genetics Of Cannabis Use

Verweij, K., Minica, C., Stringer, S., van der Most, P., Mbarek, H., Nivard, M., Abdellaoui, A., Hottenga, J-J., Martin, N., Boomsma, D., Gillespie, N., Derks, E. & Vink, J., 15 Aug 2017, In : European Neuropsychopharmacology. 27, p. S494-S495

Research output: Contribution to JournalArticleAcademicpeer-review

The low single nucleotide polymorphism heritability of plasma and saliva cortisol levels

Neumann, A., Direk, N., Crawford, A. A., Mirza, S., Adams, H. H. H., Bolton, J., Hayward, C., Strachan, D. P., Payne, E. K., Smith, J. A., Milaneschi, Y., Penninx, B., Hottenga, J. J., de Geus, E., Oldehinkel, A. J., van der Most, P. J., de Rijke, Y., Walker, B. R. & Tiemeier, H., Nov 2017, In : Psychoneuroendocrinology. 85, p. 88-95 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Saliva
Single Nucleotide Polymorphism
Hydrocortisone
Genome-Wide Association Study
Linkage Disequilibrium

Using a multivariate model to assess the interactive effects of demographics and lifestyle on the hematological profile

McArtor, D. B., Lin, B. D., Hottenga, J-J., Boomsma, D. I., Willemsen, G. & Lubke, G. H., 1 Jun 2017, In : Biomarkers in medicine. 11, 6, p. 427-438 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Biomarkers
Linear regression
Life Style
Linear Models
Demography

Using Clinical Characteristics to Identify Which Patients With Major Depressive Disorder Have a Higher Genetic Load for Three Psychiatric Disorders

Verduijn, J., Milaneschi, Y., Peyrot, W. J., Hottenga, J. J., Abdellaoui, A., de Geus, E. J. C., Smit, J. H., Breen, G., Lewis, C. M., Boomsma, D. I., Beekman, A. T. F. & Penninx, B. W. J. H., 15 Feb 2017, In : Biological Psychiatry. 81, 4, p. 316-324 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic Load
Major Depressive Disorder
Psychiatry
Schizophrenia
Bipolar Disorder

Using genetic methods to get insight into human complex traits

Lin, B., 2017, 206 p.

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File
2016

A Genome-Wide Association Meta-Analysis of Attention-Deficit/Hyperactivity Disorder Symptoms in Population-Based Pediatric Cohorts

Middeldorp, C. M., Hammerschlag, A. R., Ouwens, K. G., Blokhuis, M. M., St. Pourcain, B., Greven, C. U., Pappa, I., Tiesler, C. M. T., Ang, W., Nolte, I. M., Vilor-Tejedor, N., Bacelis, J., Ebejer, J. L., Zhao, H., Davies, G. E., Ehli, E. A., Evans, D. M., Fedko, I. O., Guxens, M., Hottenga, J. J. & 31 othersHudziak, J. J., Jugessur, A., Kemp, J. P., Krapohl, E., Martin, N. G., Murcia, M., Myhre, R., Ormel, J., Ring, S. M., Standl, M., Stergiakouli, E., Stoltenberg, C., Thiering, E., Timpson, N. J., Trzaskowski, M., van der Most, P. J., Wang, C., Nyholt, DR., Medland, S. E., Neale, B. M., Jacobsson, B., Sunyer, J., Hartman, C. A., Whitehouse, A. J. O., Pennell, C. E., Heinrich, J., Plomin, R., Davey Smith, G., Tiemeier, H., Posthuma, D. & Boomsma, D. I., 2016, In : Journal of the American Academy of Child and Adolescent Psychiatry. 55, 10, p. 896-905 10.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-Wide Association Study
Attention Deficit Disorder with Hyperactivity
Single Nucleotide Polymorphism
Meta-Analysis
Pediatrics

A meta-analysis of 120,246 individuals identifies 18 new loci for fibrinogen concentration

de Vries, P. S., Chasman, D. I., Sabater-Lleal, M., Chen, M. H., Huffman, J. E., Steri, M., Tang, W., Teumer, A., Marioni, R. E., Grossmann, V., Hottenga, J. J., Willemsen, G., de Geus, E. J. C., Boomsma, D. I., Cucca, F., Tracy, R., Watkins, H., Reiner, A. P., Folsom, A. R., Ridker, P. M. & 4 othersO'Donnell, C. J., Smith, N. L., Strachan, D. P. & Dehghan, A., 2016, In : Human Molecular Genetics. 25, 2, p. 358-370

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Fibrinogen
Meta-Analysis
X Chromosome
Genome
Genome-Wide Association Study

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

Ried, J. S., Jeff, J. M., Chu, A. Y., Bragg-Gresham, J. L., van Dongen, J., Huffman, J. E., Ahluwalia, T. S., Cadby, G., Eklund, N., Eriksson, J., de Geus, E. J. C., Hottenga, J. J., Penninx, B. W. J. H., Willemsen, G., Boomsma, D. I., McCarthy, M. I., North, K. E., O'Connell, J. R., Schlessinger, D., Thorsteinsdottir, U. & 5 othersStrachan, D. P., Frayling, T. M., Hirschhorn, J. N., Müller-Nurasyid, M. & Loos, R. J. F., 2016, In : Nature Communications. 7, 13357.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
loci
Principal Component Analysis
phenotype
Meta-Analysis
Phenotype

Associations between smoking and caffeine consumption in two European cohorts

Treur, J. L., Taylor, A. E., Ware, J. J., McMahon, G., Hottenga, J. J., Baselmans, B. M. L., Willemsen, G., Boomsma, D. I., Munafò, M. & Vink, J. M., 2016, In : Addiction. 111, 6, p. 1059-1068

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Caffeine
Smoking
Confidence Intervals
Netherlands
Energy Drinks

Blood lipids influence DNA methylation in circulating cells

Dekkers, K. F., van Iterson, M., Slieker, R. C., Moed, M. H., Bonder, M. J., van Galen, M., Mei, H., Zhernakova, D. V., Van den Berg, L. H., Deelen, J., van Dongen, J., van Heemst, D., Hofman, A., Hottenga, J. J., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., Tigchelaar, E. F., Uitterlinden, A. G., Willemsen, G. & 14 othersZhernakova, A., Franke, L., 't Hoen, P. A. C., Jansen, R., van Meurs, J., Boomsma, D. I., van Duijn, C. M., van Greevenbroek, M. M. J., Veldink, J. H., Wijmenga, C., van Zwet, E. W., Slagboom, P. E., Jukema, J. W. & Heijmans, B. T., 2016, In : Genome Biology. 17, 138, p. 1-12

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
methylation
DNA methylation
DNA Methylation
blood lipids
blood

Causes of variation in the neutrophil-lymphocyte and platelet-lymphocyte ratios: a twin-family study

Lin, B., Hottenga, J. J., Abdellaoui, A., Dolan, C. V., de Geus, E. J. C., Kluft, C., Boomsma, D. I. & Willemsen, G., 2016, In : Biomarkers in medicine. 10, 10, p. 1061-1072

Research output: Contribution to JournalArticleAcademicpeer-review

Twin Studies
Lymphocytes
Platelets
Neutrophils
Blood Platelets

Computational approaches in genetics with a focus on GoNL and twin studies

Fedko, I. O., 2016

Research output: PhD ThesisPhD Thesis - Research VU, graduation VUAcademic

Open Access
File
Twin Studies

Detection of gene-environment interaction in pedigree data using genome-wide genotypes

Nivard, M. G., Middeldorp, C. M., Lubke, G. H., Hottenga, J. J., Abdellaoui, A., Boomsma, D. I. & Dolan, C. V., 2016, In : European Journal of Human Genetics. 24, 12, p. 1803-1809

Research output: Contribution to JournalArticleAcademicpeer-review

Gene-Environment Interaction
Pedigree
Single Nucleotide Polymorphism
Body Mass Index
Genotype

Gene expression in major depressive disorder.

Jansen, R., Penninx, B. W. J. H., Madar, V., Xia, K., Milaneschi, Y., Hottenga, J. J., Hammerschlag, A. R., Beekman, A. T. F., van der Wee, N., Smit, J. H., Brooks, A. I., Tischfield, J., Posthuma, D., Schoevers, R., Grootheest, G., Willemsen, G., de Geus, E. J. C., Boomsma, D. I., Wright, F. A., Zou, F. & 2 othersSun, W. & Sullivan, P. F., 2016, In : Molecular Psychiatry. 21, p. 339 347 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Major Depressive Disorder
Gene Expression
Multigene Family
Natural Killer Cells
Interleukin-6

Genetic and environmental influences interact with age and sex in shaping the human methylome

van Dongen, J., Nivard, M. G., Willemsen, G., Hottenga, J. J., Helmer, Q., Dolan, C. V., Ehli, E. A., Davies, G. E., van Iterson, M., Breeze, C. E., Beck, S., Pool, R., Suchiman, H. E. D., Jansen, R., van Meurs, J. B., Heijmans, B. T., Slagboom, P. E. & Boomsma, D. I., 2016, In : Nature Communications. 7, 11115, p. 1-13 11115.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
methylation
genome
Methylation
Genes
Genome

Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight

Tyrrell, J., Richmond, R. C., Palmer, T. M., Feenstra, B., Rangarajan, J., Metrustry, S., Cavadino, A., Paternoster, L., Armstrong, L. L., De Silva, N. M. G., Wood, A. R., Horikoshi, M., Geller, F., Myhre, R., Bradfield, J. P., Kreiner-Møller, E., Huikari, V., Painter, J. N., Hottenga, J. J., Allard, C. & 44 othersBerry, D. J., Bouchard, L., Das, S., Evans, D. M., Hakonarson, H., Hayes, M. G., Heikkinen, J., Hofman, A., Knight, B., Lind, P. A., McCarthy, M. I., McMahon, G., Medland, S. E., Melbye, M., Morris, A. P., Nodzenski, M., Reichetzeder, C., Ring, S. M., Sebert, S., Sengpiel, V., Sørensen, T. I. A., Willemsen, G., de Geus, E. J. C., Martin, N. G., Spector, T. D., Power, C., Järvelin, M. R., Bisgaard, H., Grant, S. F. A., Nohr, E. A., Jaddoe, V. W., Jacobsson, B., Murray, J. C., Hocher, B., Hattersley, A. T., Scholtens, D. M., Davey Smith, G., Hivert, M. F., Felix, J. F., Hyppönen, E., Lowe, W. L., Frayling, T. M., Lawlor, D. A. & Freathy, R. M., 2016, In : JAMA. 315, 11, p. 1129-1140

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Birth Weight
Obesity
Mothers
Body Mass Index
Blood Pressure

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

Franke, B., Stein, J. L., Ripke, S., Anttila, V., Hibar, D. P., van Hulzen, K. J. E., Arias-Vasquez, A., Smoller, J. W., Nichols, T. E., Neale, M. C., McIntosh, A. M., Lee, P., McMahon, F. J., Meyer-Lindenberg, A., Mattheisen, M., Andreassen, O. A., Gruber, O., Sachdev, P. S., Roiz-Santiañez, R., Saykin, A. J. & 20 othersEhrlich, S., Mather, K. A., Turner, J. A., Schwarz, E., Thalamuthu, A., Yao, Y., Ho, Y. Y. W., Martin, N. G., Wright, M. J., den Braber, A., Fedko, I. O., Hottenga, J. J., van t Ent, D., Boomsma, D. I., de Geus, E. J. C., O'Donovan, M. C., Thompson, P. M., Neale, B. M., Medland, S. E. & Sullivan, P. F., 2016, In : Nature Neuroscience. 19, 3, p. 420-431

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.

Okbay, A., Baselmans, B. M. L., de Neve, J. E., Turley, P., Nivard, M. G., Fontana, M. A., Meddens, S. F. W., Karlsson Linnér, R., Rietveld, C. A., Derringer, J., de Vlaming, R., Minica, C. C., Hottenga, J. J., Vinkhuyzen, A. A. E., Boomsma, D. I., de Geus, E. J. C., Medland, S. E., Meyer, M. N., Pickrell, J. K., Esko, T. & 6 othersKrueger, R. F., Beauchamp, J., Koellinger, P. D., Benjamin, D. J., Bartels, M. & Cesarini, D., 2016, In : Nature Genetics. 48, 6, p. 624-633

Research output: Contribution to JournalArticleAcademicpeer-review

Genome
Depression
Phenotype
Genome-Wide Association Study
Sample Size

Genetic variants in RBFOX3 are associated with sleep latency

Amin, N., Allebrandt, K. V., Spek, A., Müller-Myhsok, B., Hek, K., Teder-Laving, M., Hayward, C., Esko, T., van Mill, J. G., Mbarek, H., Watson, N. F., Melville, S. A., Del Greco, M. F., Byrne, E. M., Oole, E., Kolcic, I., Chen, T., Evans, D. S., Coresh, J., Vogelzangs, N. & 55 othersKarjalainen, J., Willemsen, G., Gharib, S. A., Zgaga, L., Mihailov, E., Stone, K. L., Campbell, H., Brouwer, R. W. W., Demirkan, A., Isaacs, A., Dogas, Z., Marciante, K., Campbell, S., Borovecki, F., Luik, A. I., Li, M., Hottenga, J. J., Huffman, J. E., van den Hout, M. C. G. N., Cummings, S. R., Aulchenko, Y. S., Gehrman, P. R., Uitterlinden, A. G., Wichmann, H. E., Müller-Nurasyid, M., Fehrmann, R. S. N., Montgomery, G. W., Hofman, A., Hong, W., Kao, L., Oostra, B. A., Wright, A. F., Vink, J. M., Wilson, J. F., Pramstaller, P. P., Hicks, A. A., Polasek, O., Punjabi, N. M., Redline, S., Psaty, B. M., Heath, A. C., Merrow, M., Tranah, G. J., Gottlieb, D. J., Boomsma, D. I., Martin, N. G., Rudan, I., Tiemeier, H., van Ijcken, W. F. J., Penninx, B. W. J. H., Metspalu, A., Meitinger, T., Franke, L., Roenneberg, T. & van Duijn, C. M., 2016, In : European Journal of Human Genetics. 24, 10, p. 1488-1495

Research output: Contribution to JournalArticleAcademicpeer-review

Sleep
Genes
Genome-Wide Association Study
Single Nucleotide Polymorphism
Meta-Analysis

Genetic variants linked to education predict longevity.

Marioni, R. E., Ritchie, S. J., Joshi, P. K., Hagenaars, S. P., Okbay, A., Fischer, K., Adams, M. J., Hill, W. D., Davies, G., Abdellaoui, A., Hottenga, J. J., Willemsen, G., Boomsma, D. I., Nagy, R., Amador, C., Läll, K., Metspalu, A., Liewald, D. C., Campbell, A., Wilson, J. F. & 6 othersHayward, C., Esko, T., Porteous, D. J., Gale, C. R., Deary, I. J. & de Vlaming, R., 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, p. 13366-13371 47.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

Felix, J. F., Bradfield, J. P., Monnereau, C., van der Valk, R. J. P., Stergiakouli, E., Chesi, A., Gaillard, R., Feenstra, B., Thiering, E., Kreiner-Møller, E., Blokhuis, M. M., Horikoshi, M., Hottenga, J. J., Middeldorp, C. M., Uitterlinden, A. G., Plomin, R., Boomsma, D. I., Heinrich, J., Melbye, M., Rivadeneira, F. & 7 othersHakonarson, H., Ring, S. M., Davey Smith, G., Sørensen, T. I. A., Timpson, N. J., Grant, S. F. A. & Jaddoe, V. W. V., 2016, In : Human Molecular Genetics. 25, 2, p. 389-403

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide associations for birth weight and correlations with adult disease

Horikoshi, M., Beaumont, R. N., Day, F. R., Warrington, N. M., Kooijman, M. N., Fernandez-Tajes, J., Feenstra, B., van Zuydam, N. R., Gaulton, K. J., Grarup, N., Hottenga, J. J., Rahmioglu, N., Nyholt, DR., van Beijsterveldt, C. E. M., Willemsen, G., de Geus, E. J. C., Boomsma, D. I., Frayling, T. M., Davey Smith, G., Morris, A. P. & 7 othersOng, K. K., Felix, J. F., Timpson, N. J., Perry, J. R. B., Evans, D. M., McCarthy, M. I. & Freathy, R. M., 2016, In : Nature. 538, 7624, p. 248-252

Research output: Contribution to JournalArticleAcademicpeer-review

Birth Weight
Genome
Genome-Wide Association Study
Metabolic Diseases
Type 2 Diabetes Mellitus

Genome-wide association study identifies 74 loci associated with educational attainment

Okbay, A., Beauchamp, J., Fontana, M. A., Lee, J. J., Pers, T. H., Rietveld, C. A., Turley, P., Chen, G. B., Emilsson, V., Meddens, S. F. W., de Vlaming, R., Abdellaoui, A., Peyrot, W., Vinkhuyzen, A. A. E., Hottenga, J. J., Willemsen, G., Boomsma, D. I., Penninx, B. W. J. H., Laibson, D., Medland, S. E. & 8 othersMeyer, M. N., Yang, J., Johannesson, M., Visscher, P. M., Esko, T., Koellinger, P. D., Cesarini, D. & Benjamin, D. J., 2016, In : Nature. 533, 7604, p. 539-542

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-Wide Association Study
Phenotype
Proxy
Cognition
Single Nucleotide Polymorphism

Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium

Stringer, S., Minică, C. C., Verweij, K. J. H., Mbarek, H., Bernard, M., Derringer, J., van Eijk, K. R., Isen, J. D., Loukola, A., Maciejewski, D. F., Mihailov, E., van der Most, P. J., Sánchez-Mora, C., Roos, L., Sherva, R., Walters, R., Ware, J. J., Abdellaoui, A., Bigdeli, T. B., Branje, S. J. T. & 60 othersBrown, S. A., Bruinenberg, M., Casas, M., Esko, T., Garcia-Martinez, I., Gordon, S. D. S., Harris, J. M., Hartman, C. A., Henders, A. K., Heath, A. C., Hickie, I. B., Hickman, M., Hopfer, C. J., Hottenga, J. J., Huizink, A. C., Irons, D. E., Kahn, R. S., Korhonen, T., Kranzler, H. R., Krauter, K., van Lier, P. A. C., Lubke, G. H., Madden, P. A. F., Mägi, R., McGue, M. K., Medland, S. E., Meeus, W. H. J., Miller, M. B., Montgomery, G. W., Nivard, M. G., Nolte, I. M., Oldehinkel, A. J., Pausova, Z., Qaiser, B., Quaye, L., Ramos-Quiroga, J. A., Richarte, V., Rose, R. J., Shin, J., Stallings, M. C., Stiby, A. I., Wall, T. L., Wright, M. J., Koot, H. M., Paus, T., Hewitt, J. K., Ribasés, M., Kaprio, J., Boks, M. P. M., Snieder, H., Spector, T., Munafò, M. R., Metspalu, A., Gelernter, J., Boomsma, D. I., Iacono, W. G., Martin, N. G., Gillespie, N. A., Derks, E. M. & Vink, J. M., 29 Mar 2016, In : Translational Psychiatry. 6, p. e769

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Genome-Wide Association Study
Cannabis
Single Nucleotide Polymorphism
Genome
Genes

Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2

Ware, J. J., Chen, X., Vink, J. M., Loukola, A., Minica, C. C., Pool, R., Milaneschi, Y., Mangino, M., Menni, C., Chen, J., Peterson, R. E., Auro, K., Lyytikäinen, L. P., Wedenoja, J., Stiby, A. I., Hemani, G., Willemsen, G., Hottenga, J. J., Korhonen, T., Heliövaara, M. & 18 othersPerola, M., Rose, R. J., Paternoster, L., Timpson, N., Wassenaar, C. A., Zhu, A. Z. X., Davey Smith, G., Raitakari, O. T., Lehtimäki, T., Kähönen, M., Koskinen, S., Spector, T. D., Penninx, B. W. J. H., Salomaa, V., Boomsma, D. I., Tyndale, R. F., Kaprio, J. & Munafò, M., 2016, In : Scientific Reports. 6, 20092, 20092.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Cotinine
Genome-Wide Association Study
Tobacco Products
Meta-Analysis
Nicotine

Genome-wide pleiotropy of adult aggression and blood metabolites

Hagenbeek, F. A., Nivard, M. G., Pool, R., van Dongen, J., Hottenga, J. J., Abdellaoui, A., Willemsen, G., Vink, J. M., Ligthart, R. S. L., Harms, A., Hankemeier, T., Bartels, M. & Boomsma, D. I., 2016, In : Behavior Genetics. 46, 6, p. 772-816

Research output: Contribution to JournalMeeting AbstractOther research output

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

Kettunen, J., Demirkan, A., Würtz, P., Draisma, H. H. M., Haller, T., Rawal, R., Vaarhorst, A. A. M., Kangas, A. J., Lyytikäinen, L. P., Pirinen, M., Pool, R., Sarin, A-P., Soininen, P., Tukiainen, T., Wang, Q., Tiainen, M., Tynkkynen, T., Amin, N., Zeller, T., Beekman, M. & 30 othersDeelen, J., Willems van Dijk, K., Esko, T., Hottenga, J. J., van Leeuwen, E. M., Lehtimäki, T., Mihailov, E., Rose, R. J., de Craen, A. J., Gieger, C., Kähönen, M., Perola, M., Blankenberg, S., Savolainen, M. J., Verhoeven, A., Viikari, J., Willemsen, G., Boomsma, D. I., van Duijn, C. M., Eriksson, J., Jula, A., Järvelin, M. R., Kaprio, J., Metspalu, A., Raitakari, O., Salomaa, V., Slagboom, P. E., Waldenberger, M., Ripatti, S. & Ala-Korpela, M., 2016, In : Nature Communications. 7, 11122.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
lipoproteins
Lipoprotein(a)
genome
metabolites
Genome-Wide Association Study

Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research

Spjuth, O., Krestyaninova, M., Hastings, J., Shen, H. Y., Heikkinen, J., Waldenberger, M., Langhammer, A., Ladenvall, C., Esko, T., Persson, M. Å., Heggland, J., Dietrich, J., Ose, S., Gieger, C., Ried, J. S., Peters, A., Fortier, I., de Geus, E. J. C., Klovins, J., Zaharenko, L. & 16 othersWillemsen, G., Hottenga, J. J., Litton, J. E., Karvanen, J., Boomsma, D. I., Groop, L., Rung, J., Palmgren, J., Pedersen, N. L., McCarthy, M. I., van Duijn, C. M., Hveem, K., Metspalu, A., Ripatti, S., Prokopenko, I. & Harris, J. R., 2016, In : European Journal of Human Genetics. 24, 4, p. 521-528

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Privacy
Blood Vessels
Molecular Epidemiology
Vocabulary
Research

Identification of Common Genetic Variants Influencing Spontaneous Dizygotic Twinning and Female Fertility

Mbarek, H., Steinberg, S., Nyholt, DR., Gordon, S. D., Miller, M. B., McRae, A. F., Hottenga, J. J., Day, F. R., Willemsen, G., de Geus, E. J. C., Davies, G. E., Martin, H. C., Penninx, B. W. J. H., Jansen, R., McAloney, K., Vink, J. M., Kaprio, J., Plomin, R., Spector, T. D., Magnusson, P. K. & 17 othersReversade, B., Harris, R. A., Aagaard, K., Kristjansson, R. P., Olafsson, I., Eyjolfsson, G. I., Sigurdardottir, O., Iacono, W. G., Lambalk, C. B., Montgomery, G. W., McGue, M., Ong, K. K., Perry, J. R. B., Martin, N. G., Stefansson, H., Stefansson, K. & Boomsma, D. I., 2016, In : American Journal of Human Genetics. 98, 5, p. 898-908

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Fertility
Mothers
Dizygotic Twins
Genome-Wide Association Study
Single Nucleotide Polymorphism

KLB is associated with alcohol drinking, and its gene product B-Klotho is necessary for FGF21 regulation of alcohol preference

Schumann, G., Liu, C., O'Reilly, P., Gao, H., Song, P., Xu, B., Ruggeri, B., Amin, N., Jia, T., Preis, S. R., Hottenga, J. J., Mbarek, H., Boomsma, D. I., de Geus, E. J. C., Penninx, B. W. J. H., Bakalkin, G., Evangelou, E., Liu, Y., Rice, K. M., Desrivieres, S. & 5 othersKliewer, S. A., Mangelsdorf, D. J., Müller, C. P., Levy, D. & Elliott, P., 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 50, p. 14372-14377

Research output: Contribution to JournalArticleAcademicpeer-review

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, R. S. L., Terwindt, G. M., Kallela, M., Freilinger, T., Ran, C., Gordon, S. G., Stam, A. H. & 88 othersSteinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A. P., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Ridker, P. M., Gudlaug Hrafnsdottir, M., Stefansson, H., Ring, S. M., Hottenga, J. J., Penninx, B. W. J. H., Färkkilä, M., Artto, V., Kaunisto, M. A., Vepsäläinen, S., Malik, R., Heath, A. C., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Kurki, M. I., Kals, M., Mägi, R., Pärn, K., Hämaläinen, E., Huang, H., Byrnes, A. E., Franke, L., Huang, J., Stergiakouli, E., Lee, P. H., Sandor, C., Webber, C., Cader, Z., Müller-Myhsok, B., Schreiber, S., Meitinger, T., Eriksson, J. G., Salomaa, V., Heikkilä, K., Loehrer, A. G., Uitterlinden, A. G., Hofman, A., van Duijn, C. M., Cherkas, L., Pedersen, L., Stubhaug, A., Nielsen, C. S., Männikkö, M., Mihailov, E., Milani, L., Göbel, H., Esserlind, A. L., Francke Christensen, A., Folkmann Hansen, T., Werge, T., Kaprio, J., Aromaa, A., Raitakari, O., Ikram, M. A., Spector, T. D., Järvelin, M. R., Metspalu, A., Kubisch, C., Strachan, D. P., Ferrari, M. D., Belin, A. C., Dichgans, M., Wessman, M., van den Maagdenberg, A. M. J. M., Zwart, J. A., Boomsma, D. I., Davey Smith, G., Stefansson, K., Eriksson, N., Daly, M. J., Neale, B. M., Olesen, J., Chasman, D. I., Nyholt, DR., Palotie, A. & Posthuma, D., 2016, In : Nature Genetics. 48, 8, p. 856-866

Research output: Contribution to JournalArticleAcademicpeer-review

Migraine Disorders
Meta-Analysis
Genome-Wide Association Study
Nervous System Diseases
Vascular Diseases

Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium

van den Berg, S. M., de Moor, M. H. M., Verweij, C. J. H., Krueger, R. F., Luciano, M., Vasquez, A. A., Matteson, L. K., Derringer, J., Esko, T., Amin, N., Gordon, S. D., Hansell, N. K., Hart, A. B., Seppälä, I., Huffman, J. E., Konte, B., Lahti, J., Miller, M., Nutile, T., Tanaka, T. & 95 othersTeumer, A., Viktorin, A., Wedenoja, J., Abdellaoui, A., Abecasis, G. R., Adkins, D. E., Agrawal, A., Allik, J., Appel, K., Bigdeli, T. B., Busonero, F., Campbell, H., Costa, P. T., Davey Smith, G., Davies, G., de Wit, H., Ding, J., Engelhardt, B. E., Eriksson, J. G., Fedko, I. O., Ferrucci, L., Franke, B., Giegling, I., Grucza, R., Hartmann, A. M., Heath, A. C., Heinonen, K., Henders, A. K., Homuth, G., Hottenga, J. J., Iacono, W. G., Janzing, J., Jokela, M., Karlsson, R., Kemp, J. P., Kirkpatrick, M. G., Latvala, A., Lehtimäki, T., Liewald, D. C., Madden, P. A. F., Magri, C., Magnusson, P. K. E., Marten, J., Maschio, A., Mbarek, H., Medland, S. E., Mihailov, E., Milaneschi, Y., Montgomery, G. W., Nauck, M., Nivard, M. G., Ouwens, K. G., Palotie, A., Pettersson, E., Polasek, O., Qian, Y., Pulkki-Raback, L., Raitakari, O. T., Realo, A., Rose, R. J., Ruggiero, D., Schmidt, C. O., Slutske, W. S., Sorice, R., Starr, J. M., St Pourcain, B., Sutin, A. R., Timpson, N. J., Trochet, H., Zgaga, L., Porteous, D., Minelli, A., Palmer, A. A., Rujescu, D., Ciullo, M., Hayward, C., Rudan, I., Metspalu, A., Kaprio, J., Deary, I. J., Räikkönen, K., Wilson, J. F., Keltikangas-Järvinen, L., Bierut, L. J., Hettema, J. M., Grabe, H. J., Penninx, B. W. J. H., van Duijn, C. M., Evans, D. M., Schlessinger, D., Pedersen, N. L., Terracciano, A., McGue, M., Martin, N. G. & Boomsma, D. I., 2016, In : Behavior Genetics. 46, 2, p. 170-182

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Genome-Wide Association Study
meta-analysis
Personality
Meta-Analysis
genome

Meta-analysis of genome-wide association studies of anxiety disorders

Otowa, T., Hek, K., Byrne, E. M., Mirza, S. S., Nivard, M. G., Bigdeli, T. B., Aggen, S. H., Adkins, D. E., Wolen, A., Fanous, A., Keller, M. C., Castelao, E., Kutalik, Z., van der Auwera, S. V., Homuth, G., Nauck, M., Teumer, A., Milaneschi, Y., Hottenga, J. J., Direk, N. & 26 othersHofman, A., Uitterlinden, A. G., Mulder, C. L., Henders, A. K., Medland, S. E., Gordon, S., Heath, A. C., Madden, P. A. F., Pergadia, M. L., van der Most, P. J., Nolte, I. M., van Oort, F. V. A., Hartman, C. A., Oldehinkel, A. J., Preisig, M., Grabe, H. J., Middeldorp, C. M., Penninx, B. W. J. H., Boomsma, D. I., Martin, N. G., Montgomery, G. W., Maher, B. S., van den Oord, E. J., Wray, N. R., Tiemeier, H. & Hettema, J. M., 2016, In : Molecular Psychiatry. 21, 10, p. 1391-1399

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-Wide Association Study
Anxiety Disorders
Meta-Analysis
Phenotype
Genome

Multivariate and repeated measure GWAS of aggression phenotypes

Nivard, M., Middeldorp, C., Hottenga, J-J., Fedko, I., Ehli, E. A., Davies, G., van Beijsterveldt, C., Bartels, M. & Boomsma, D., Nov 2016, In : Behavior Genetics. 46, 6, p. 798-799

Research output: Contribution to JournalMeeting AbstractOther research output

Novel genetic loci underlying human intracranial volume identified through genome-wide association

Adams, H. H. H., Hibar, D. P., Chouraki, V., Stein, J. L., Nyquist, P. A., Renteria, M. E., Trompet, S., Arias Vazquez, A., Seshadri, S., Desrivieres, S., den Braber, A., Boomsma, D. I., de Geus, E. J. C., Fedko, I. O., Hottenga, J. J., Hulshoff Pol, H. E., Penninx, B. W. J. H., de Craen, A. J., Wright, M. J., Launer, L. J. & 8 othersSchumann, G., van t Ent, D., Fornage, M., Franke, B., Debette, S., Medland, S. E., Arfan Ikram, M. & Thompson, P. M., 2016, In : Nature Neuroscience. 19, 12, p. 1569-1582

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic Loci
Genome
Genome-Wide Association Study
Phosphatidylinositol 3-Kinases
Cognition

Obsessive–compulsive symptoms in a large population-based twin-family sample are predicted by clinically based polygenic scores and by genome-wide SNPs

den Braber, A., Rodrigues Zilhao Nogueira, N., Fedko, I. O., Hottenga, J. J., Pool, R., Smit, D. J. A., Cath, D. C. & Boomsma, D. I., 2016, In : Translational Psychiatry. 6, e731

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Personality Polygenes, Positive Affect, and Life Satisfaction.

Weiss, A., Baselmans, B. M. L., Hofer, E., Yang, J., Okbay, A., Lind, P. A., Miller, M. B., Nolte, I. M., Zhao, W., Hagenaars, S. P., Hottenga, J. J., Matteson, L. K., Snieder, H., Faul, J. D., Hartman, C. A., Boyle, P. A., Tiemeier, H., Mosing, M. A., Pattie, A., Davies, G. & 26 othersLiewald, D. C., Schmidt, R., Jager, P. L., Heath, A. C., Jokela, M., Starr, J. M., Oldehinkel, A. J., Johannesson, M., Cesarini, D., Hofman, A., Harris, S. E., Smith, J. A., Keltikangas-Järvinen, L., Pulkki-Råback, L., Schmidt, H., Smith, J., Iacono, W. G., McGue, M., Bennett, D. A., Pedersen, N. L., Magnusson, P. K. E., Deary, I. J., Martin, N. G., Boomsma, D. I., Bartels, M. & Luciano, M., 2016, In : Twin Research and Human Genetics. 19, p. 407-417 5.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Personality
Equipment and Supplies
Genome
Personality Inventory
Genetic Research

Polygenic dissection of major depression clinical heterogeneity

Milaneschi, Y., Winkelman, F., Peyrot, W., Abdellaoui, A., Willemsen, G., Hottenga, J. J., Jansen, R., Mbarek, H., Dehghan, A., Lu, C., Boomsma, D. I. & Penninx, B. W. J. H., 2016, In : Molecular Psychiatry. 21, 4, p. 516-522

Research output: Contribution to JournalArticleAcademicpeer-review

Major Depressive Disorder
Dissection
Depression
Psychiatry
Odds Ratio

Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs

Ricano-Ponce, I., Zhernakova, D. V., Deelen, P., Luo, O., Li, X., Isaacs, A., Karjalainen, J., Di. Tommaso, J., Borek, Z. A., Zorro, M. M., Gutierrez-Achury, J., Uitterlinden, A. G., Hofman, A., van Meurs, J., Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J., Neteaf, M. G., Jonkers, I. H. & 7 othersWithoff, S., van Duijn, C. M., Li, Y., Ruan, Y., Franke, L., Wijmenga, C. & Kumar, V., 2016, In : Journal of Autoimmunity. 68, p. 62-74

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

The Genetic Overlap Between Hair and Eye Color

Lin, B., Willemsen, G., Abdellaoui, A., Bartels, M., Ehli, E. A., Davies, G. E., Boomsma, D. I. & Hottenga, J. J., 2016, In : Twin Research and Human Genetics. 19, 6, p. 595-599

Research output: Contribution to JournalArticleAcademicpeer-review

Hair Color
Eye Color
Netherlands
Phenotype
Genome-Wide Association Study

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Ehret, G. B., Ferreira, T., Chasman, D. I., Jackson, A. U., Schmidt, E. M., Johnson, T., Thorleifsson, G., Luan, J., Donnelly, L. A., Kanoni, S., Jansen, R., Boomsma, D. I., Hottenga, J. J., Penninx, B. W. J. H., van Duijn, C. M., Wichmann, H. E., Palmer, C. N. A., Stefansson, K., Ridker, P. M., Loos, R. J. F. & 5 othersChakravarti, A., Deloukas, P., Morris, A. P., Newton-Cheh, C. & Munroe, P. B., 2016, In : Nature Genetics. 48, 10, p. 1171-1184

Research output: Contribution to JournalArticleAcademicpeer-review

Blood Pressure
Single Nucleotide Polymorphism
Kidney
Blood Vessels
Endothelial Cells
2015

CNV Concordance in 1,097 MZ Twin Pairs

Abdellaoui, A., Ehli, E. A., Hottenga, J. J., Weber, Z., Mbarek, H., Willemsen, G., van Beijsterveldt, C. E. M., Brooks, A., Hudziak, J. J., Sullivan, P. F., de Geus, E. J. C., Davies, G. E. & Boomsma, D. I., 2015, In : Twin Research and Human Genetics. 18, 1, p. 1-12 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Monozygotic Twins
Cheek
DNA
Epithelium
Overlapping Genes

Common genetic variants influence human subcortical brain structures

Hibar, D. P., Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., Jahanshad, N., Toro, R., Wittfeld, K., Abramovic, L., Andersson, M., Aribisala, B. S., Armstrong, N. J., Bernard, M., Bohlken, M. M., Biks, M. P., Bralten, J., Brown, A. A., Chakravarty, M. M., Chen, Q., Ching, C. R. K. & 267 othersCuellar-Partida, G., den Braber, A., Giddaluru, S., Goldman, A. L., Grimm, O., Guadalupe, T., Hass, J., Woldehawariat, G., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Olde Loohuis, L. M., Luciano, M., Macare, C., Mather, K. A., Mattheisen, M., Milaneschi, Y., Nho, K., Papmeyer, M., Ramasamy, A., Risacher, S. L., Roiz-Santiañez, R., Rose, E. J., Salami, A., Sämann, P. G., Schmaal, L., Schork, A. J., Shin, J., Strike, L. T., Teumer, A., Donkelaar, M. M. J., van Eijk, K. R., Walters, R. K., Westlye, L. T., Welan, C. D., Winkler, A. M., Zwiers, M. P., Alhusaini, S., Athanasiu, L., Ehrlich, S., Hakobjan, M. M. H., Hartberg, C. B., Haukvik, U. K., Heister, A. J. G. A. M., Hoehn, D., Kasperaviciute, D., Liewald, D. C. M., Lopez, L. M., Makkinje, R. R., Matarin, M., Naber, M. A. M., Reese McKay, D., Needham, M., Nugent, A. C., Pütz, B., Royle, N. A., Shen, L., Sprooten, E., Trabzuni, D., van der Marel, S. S. L., van Hulzen, K. J. E., Walton, E., Wolf, C., Almasy, L., Ames, D., Arepalli, S., Assareh, A. A., Bastin, M. E., Brodaty, H., Bulayeva, K. B., Carless, M. A., Cichon, S., Corvin, A., Curran, J. E., Czisch, M., de Zubicaray, G. I., Dillman, A., Duggirala, R., Dyer, T. D., Erk, S., Fedko, I. O., Ferrucci, L., Foroud, T. M., Fox, P. T., Fukunaga, M., Gibbs, J. R., Göring, H. H. H., Green, R. C., Guelfi, S., Hansell, N. K., Hartman, C. A., Hegenscheid, K., Heinz, A., Hernandez, D. G., Heslenfeld, D. J., Hoekstra, P. J., Holsboer, F., Homuth, G., Hottenga, J. J., Ikeda, M., Jack, C. R. . J., Jenkinson, M., Johnson, R., Kanai, R., Keil, M., Kent, J. W. J., Kochunov, P., Kwok, J. B., Lawrie, S. M., Liu, X., Longo, D. L., McMahon, K. L., Meisenzahl, E., Melle, I., Mohnke, S., Montgomery, G. W., Mostert, J. C., Mühleisen, T. W., Nalls, M. A., Nichols, T. E., Nilsson, L. G., Nöthen, M. M., Ohi, K., Olvera, R. L., Perez-Iglesias, R., Pike, G. B., Potkin, S. G., Reinvang, I., Reppermund, S., Rietschel, M., Romanczuk-Seiferth, N., Rosen, G. D., Rujescu, D., Schnell, K., Schofield, P. R., Smith, C., Steen, V. M., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Valdés Hernández, M. C., van t Ent, D., van der Brug, M., van der Wee, N. J. A., van Tol, M. J., Veltman, D. J., Wassink, T. H., Westmann, E., Zielke, R. H., Zonderman, A. B., Ashbrook, D. G., Hager, R., Lu, L., McMahon, F. J., Morris, D. W., Williams, R. W., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Cahn, W., Calhoun, V. D., Cavalleri, G. L., Crespo-Facorro, B., Dale, A. M., Davies, G. E., Delanty, N., Depondt, C., Djurovic, S., Drevets, W. C., Espeseth, T., Gollub, R. L., Ho, B. C., Hoffmann, W., Hosten, N., Kahn, R. S., Le Hellard, S., Meyer-Lindenberg, A., Müller-Myhsok, B., Nauck, M., Nyberg, L., Pandolfo, M., Penninx, B. W. J. H., Roffman, J. L., Sisodiya, SM., Smoller, J. W., van Bokhoven, H., van Haren, N. E. M., Völzke, H., Walter, H., Weiner, M. W., Wen, W., White, T., Agartz, I., Andreassen, O. A., Blangero, J., Boomsma, D. I., Brouwer, R. M., Cannon, D. M., Cookson, M. R., de Geus, E. J. C., Deary, I. J., Donohoe, G., Fernandez, G., Fisher, S. E., Francks, C., Glahn, D. C., Grabe, H. J., Gruber, O., Hardy, J., Hashimoto, R., Hulshoff Pol, H. E., Jönsson, E. G., Kloszewska, I., Lovestone, S., Mattay, V. S., Mecocci, P., McDonald, C., McIntosh, A. M., Ophoff, R. A., Paus, T., Pausova, Z., Ryten, M., Sachdev, P. S., Saykin, A. J., Simmons, A., Singleton, A., Soininen, H., Wardlaw, J. M., Weale, M. E., Weinberger, D. R., Adams, H. H. H., Launer, L. J., Seiler, S., Schmidt, R., Chauhan, G., Satizabal, C. L., Becker, J. T., Yanek, L., van der Lee, S. J., Ebling, M., Fischl, B., Longstreth, J. W. T., Greve, D., Schmidt, H., Nyquist, P., Vinke, L. N., van Duijn, C. M., Xue, L., Mazoyer, B., Bis, J. C., Gudnason, V., Seshadri, S., Arfan Ikram, M., Martin, N. G., Wright, M. J., Schumann, G., Franke, B., Thompson, P. M. & Medland, S. E., 2015, In : Nature. 520, 7546, p. 224-229 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Putamen
Brain
Developmental Genes
Transport Vesicles
Caudate Nucleus

Directional dominance on stature and cognition in diverse human populations

Joshi, P. K., Esko, T., Mattsson, H., Eklund, N., Gandin, I., Nutile, T., Jackson, A. U., Schurmann, C., Smith, A. V., Zhang, W., Okada, Y., Stancáková, A., Faul, J. D., Zhao, W., Bartz, T. M., Pina Concas, M., Franceschini, N., Enroth, S., Vitart, V., Trompet, S. & 338 othersGuo, X., Chasman, D. I., O'Connel, J. R., Corre, T., Nongmaithem, S. S., Chen, Y., Mangino, M., Ruggiero, D., Traglia, M., Farmaki, A-E., Kacprowski, T., Bjonnes, A., Spek, A., Wu, Y., Giri, A. K., Yanek, L. R., Wang, L., Hofer, E., Rietveld, C. A., McLeod, O., Cornelis, M. C., Pattaro, C., Verweij, N., Baumbach, C., Abdellaoui, A., Warren, H. R., Vuckovic, D., Mei, H., Bouchard, C., Perry, J. R. B., Cappellani, S., Mirza, S. S., Benton, M. C., Broeckel, U., Medland, S. E., Lind, P. A., Malerba, G., Drong, A., Yengo, L., Bielak, L. F., Zhi, D., van der Most, P. J., Shriner, D., Mägi, R., Hemani, G., Karaderi, T., Wang, Z., Liu, T., Demuth, I., Zhao, J. H., Meng, W., Lataniotis, L., van der Laan, S. W., Brafdfield, J. P., Wood, A. R., Bonnefond, A., Ahluwalia, T. S., Hall, L. M., Salvi, E., Yazar, S., Carstensen, L., de Haan, H. G., Abney, M., Afzal, U., Allison, M. A., Amin, N., Asselbergs, F. W., Bakker, S. J. L., Barr, R. G., Baumeister, S. E., Benjamin, D. J., Bergmann, S., Boerwinkle, E., Bottinger, E. P., Campbell, A., Chakravarti, A., Chan, Y., Chanock, S. J., Chen, C., Chen, Y. D. I., Colins, F. S., Connell, J., Correa, A., Cupples, L. A., Davey Smith, G., Davies, G., Dörr, M., Ehret, G., Ellis, S. B., Feenstra, B., Feitosa, M. F., Ford, I., Fox, C. S., Frayling, T. M., Friedrich, N., Geller, F., Gillham-Nasenya, I., Gottesman, O., Graff, M., Grodstein, F., Gu, C., Haley, C., Hammond, C. J., Harris, S. E., Harris, T. B., Hastie, N. D., Heard-Costa, N. L., Heikkilä, K., Hocking, L. J., Homuth, G., Hottenga, J. J., Huang, J., Huffman, J. E., Hysi, P. G., Arfan Ikram, M., Ingelsson, E., Joensuu, A., Johansson, A., Jousilahti, P., Jukema, J. 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Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Cognition
Aptitude
Inbreeding
Forced Expiratory Volume
Population

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High- Density Imputation

Horikoshi, M., Mägi, R., van de Bunt, M., Surakka, I., Sarin, A-P., Mahajan, A., Marullo, L., Thorleifsson, G., Hägg, S., Hottenga, J. J., Ladenvall, C., Ried, J. S., Winkler, T. W., Willems, S. M., Pervjakova, N., Esko, T., Beekman, M., Nelson, C. P., Willenborg, C., Wiltshire, S. & 62 othersFerreira, T., Fernandez, J., Gaulton, K. J., Steinthorsdottir, V., Hamsten, A., Magnusson, P. K. E., Willemsen, G., Milaneschi, Y., Robertson, N. R., Groves, C. J., Bennett, A. J., Lehtimäki, T., Viikari, J. S., Rung, J., Lyssenko, V., Perola, M., Heid, I. M., Herder, C., Grallert, H., Müller-Nurasyid, M., Roden, M., Hypponen, E., Isaacs, A., van Leeuwen, E. M., Karssen, L. C., Mihailov, E., Houwing-Duistermaat, J. J., de Craen, A. J., Deelen, J., Havulinna, A. S., Blades, M., Hengstenberg, C., Erdmann, J., Schunkert, H., Kaprio, J., Tobin, M. D., Samani, N. J., Lind, L., Salomaa, V., Lindgren, C. M., Slagboom, P. E., Metspalu, A., van Duijn, C. M., Eriksson, J. G., Peters, A., Gieger, C., Jula, A., Groop, L., Raitakari, O. T., Power, C., Penninx, B. W. J. H., de Geus, E. J. C., Smit, J. H., Boomsma, D. I., Pedersen, N. L., Ingelsson, E., Thorsteinsdottir, U., Stefansson, K., Ripatti, S., Prokopenko, I., McCarthy, M. I. & Morris, A. P., 2015, In : PLoS Genetics. 11, 7, 24 p., e1005230.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
obesity
Genome-Wide Association Study
genome
Obesity
Genome

Educational Attainment Influences Levels of Homozygosity through Migration and Assortative Mating

Abdellaoui, A., Hottenga, J. J., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Ehli, E. A., Davies, G. E., Brooks, A., Sullivan, P. F., Penninx, B. W. J. H., de Geus, E. J. C. & Boomsma, D. I., 2015, In : PLoS ONE. 10, 3, 14 p., e0118935.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
assortative mating
homozygosity
ancestry
spouses
Education