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Research Output 2004 2019

2009

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

Aulchenko, Y. S., Ripatti, S., Lindqvist, I., Boomsma, D. I., Heid, I. M., Pramstaller, P. P., Penninx, B. W. J. H., Janssen, A. C. J. W., Wilson, J. F., Spector, T., Martin, N. G., Pedersen, N. L., Kyvik, K. O., Kaprio, J., Hofman, A., Freimer, N. B., Jarvelin, M-R., Gyllensten, U., Campbell, H., Rudan, I. & 37 othersJohansson, A., Marroni, F., Hayward, C., Vitart, V., Jonasson, I., Pattar, C., Wright, A., Hastie, N., Pichler, I., Hicks, A. A., Falchi, M., Willemsen, G., Hottenga, J. J., de Geus, E. J. C., Montgomery, GW., Whitfield, J., Magnusson, P., Saharinen, J., Perola, M., Silander, K., Isaacs, A., Sijbrands, E. J. G., Uitterlinden, A. G., Witteman, J. C. M., Oostra, B. A., Elliott, P., Ruokonen, A., Sabatti, C., Gieger, C., Meitinger, T., Kronenberg, F., Döring, A., Wichmann, H-E., Smit, J. H., McCarthy, M. I., van Duijn, C. M. & Peltonen, L., 2009, In : Nature Genetics. 41, 1, p. 47-55

Research output: Contribution to JournalArticleAcademicpeer-review

File
Genome-Wide Association Study
Coronary Disease
Scandinavian and Nordic Countries
Lipids
LDL Cholesterol

Meta-analysis of genome-wide association results in >10.000 individuals for the big five personality traits

de Moor, M. H. M., Boomsma, D. I., de Geus, E. J. C., Willemsen, G., Hottenga, J. J., Distel, M. A., Abecasis, G. R., Terracciano, A., McCrae, R. R., Costa, P. T., Hartman, C. A., Spinhoven, P., Penninx, B. W. J. H., Esko, T., Allik, J., Realo, A., Metspalu, A., Hansell, N., Medland, S. E., Wray, N. R. & 7 othersWright, M. J., Martin, N. G., Amin, N., Aulchenko, Y. S., Janssens, A., Oostra, B. A. & van Duijn, C. M., 2009, In : Behavior Genetics. 39, p. 643

Research output: Contribution to JournalMeeting AbstractOther research output

Multicenter dizygotic twin cohort study confirms two linkage susceptibility loci for body mass index at 3q29 and 7q36 and identifies three further potential novel loci

Kettunen, J., Perola, M., Martin, N. G., Cornes, B. K., Wilson, S. G., Montgomery, GW., Benyamin, B., Harris, J. R., Boomsma, D. I., Willemsen, G., Hottenga, J. J., Slagboom, P. E., Christensen, K., Kyvik, K., Sorensen, T. I. A., Pedersen, N. L., Magnusson, P. K. E., Andrew, T., Spector, T. D., Widen, E. & 4 othersSilventoinen, K., Kaprio, J., Palotie, A. & Peltonen, L., 2009, In : International Journal of Obesity. 33, 11, p. 1235-1242

Research output: Contribution to JournalArticleAcademicpeer-review

File
Dizygotic Twins
Twin Studies
Denmark
Finland
Sweden

Sequence Variants in Three Loci Influence Monocyte Counts and Erythrocyte Volume

Ferreira, M. A. R., Hottenga, J. J., Warrington, N. M., Medland, S. E., Willemsen, G., Lawrence, R. W., Gordon, S., de Geus, E. J. C., Henders, A. K., Smit, J. H., Campbell, M. J., Wallace, L., Evans, D. M., Wright, M. J., Nyholt, DR., James, A. L., Beilby, J. P., Penninx, B. W. J. H., Palmer, L. J., Frazer, I. H. & 3 othersMontgomery, GW., Martin, N. G. & Boomsma, D. I., 2009, In : American Journal of Human Genetics. 85, 5, p. 745-749

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Erythrocyte Volume
Hematology
Monocytes
Physiological Phenomena
Erythrocyte Count

Suggestive linkage on chromosome 2, 8, and 17 for Lifetime Major Depression

Middeldorp, C. M., Sullivan, P. F., Wray, N. R., Hottenga, J. J., de Geus, E. J. C., van den Berg, M., Montgomery, GW., Coventry, W. L., Statham, D. J., Andrews, G., Slagboom, P. E., Boomsma, D. I. & Martin, N. G., 2009, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 150B, 3, p. 352-358

Research output: Contribution to JournalArticleAcademicpeer-review

File
Chromosomes, Human, Pair 8
Chromosomes, Human, Pair 17
Chromosomes, Human, Pair 2
Major Depressive Disorder
Serotonin Plasma Membrane Transport Proteins

Trends in genome wide association results of multiple phenotypes

Hottenga, J. J., 2009.

Research output: Contribution to ConferencePosterOther research output

Variants in MTNR1B influence fasting glucose levels

Prokopenko, I., Langenberg, C., Florez, J. C., Saxena, R., Soranzo, N., Thorleifsson, G., Loos, R. J. F., Manning, A. K., Jackson, A. U., Aulchenko, Y. S., Potter, S. C., Erdos, M. R., Sanna, S., Hottenga, J. J., Wheeler, E., Kaakinen, M., Lyssenko, V., Chen, W-M., Ahmadi, K., Beckmann, J. S. & 79 othersBergman, R. N., Bochud, M., Bonnycastle, L. L., Buchanan, T. A., Cao, A., Cervin, A., Coin, L., Collins, F. S., Crisponi, L., de Geus, E. J. C., Dehghan, A., Deloukas, P., Doney, A. S. F., Elliott, P., Freimer, N. B., Gateva, V., Herder, C., Hofman, A., Hughes, T. E., Hunt, S., Illig, T., Inouye, M., Isomaa, B., Johnson, T., Kong, A., Krestyaninova, M., Kuusisto, J., Laaks, M., Lim, N., Lindblad, U., Lindgren, C. M., McCann, O. T., Mohlke, K. L., Morris, A. D., Naitza, S., Orrù, M., Palmer, C. N. A., Pouta, A., Randall, J., Rathmann, W., Saramies, J., Scheet, P., Scott, L. J., Scuteri, A., Sharp, S., Sijbrands, E. J. G., Smit, J. H., Song, K., Steinthorsdottir, V., Stringham, H. M., Tuomi, T., Tuomilehto, J., Uitterlinden, A. G., Voight, B. F., Waterworth, D., Wichmann, H-E., Willemsen, G., Witteman, J. C. M., Yuan, X., Zha, J. H., Zeggini, E., Schlessinger, D., Sandhu, M., Boomsma, D. I., Uda, M., Spector, T. D., Penninx, B. W. J. H., Altshuler, D., Vollenweider, P., Jarvelin, M-R., Lakatta, E., Waeber, G., Fox, C. S., Peltonen, L., Groop, L. C., Mooser, V., Cupples, L. A., Thorsteinsdottir, U. & Abecasis, G. R., 2009, In : Nature Genetics. 41, 1, p. 77-81

Research output: Contribution to JournalArticleAcademicpeer-review

File
Melatonin MT2 Receptor
Fasting
Glucose
HapMap Project
Genetic Loci
2008

A genome-wide linkage scan for wellbeing.

Bartels, M., de Moor, M. H. M., Willemsen, G., Hottenga, J. J., Posthuma, D., Hudziak, J., Boomsma, D. I. & de Geus, E. J. C., 2008, In : Behavior Genetics. 38, p. 614-615

Research output: Contribution to JournalMeeting AbstractOther research output

Open Access
File
Migraine without Aura
Migraine Disorders
Genome
Population

A whole genome association study of neuroticism using DNA pooling.

Shifman, S., Bhomra, A., Smiley, S., Wray, N. R., James, M. R., Martin, N. G., Hettema, J. M., An, S. S., Neale, M. C., van den Oord, E. J. C. G., Kendler, K., Chen, X., Boomsma, D. I., Middeldorp, C. M., Hottenga, J. J., Slagboom, P. E. & Flint, J., 2008, In : Molecular Psychiatry. 13, 3, p. 302-312

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Genome-Wide Association Study
Single Nucleotide Polymorphism
DNA
Odds Ratio
Genome

Chromosome 9: linkage for borderline personality disorder features.

Distel, M. A., Hottenga, J. J., Trull, T. J. & Boomsma, D. I., 2008, In : Psychiatric Genetics. 18, 6, p. 302-307

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Chromosomes, Human, Pair 9
Borderline Personality Disorder
Neurofibromin 2
Genotype
Chromosomes, Human, Pair 4

Clustering of subjects on subsets of SNPs

Meulman, J. J., de Geus, E. J. C., Willemsen, G., Hottenga, J. J., Sullivan, P. F., Smit, J. H., Penninx, B. W. J. H. & Boomsma, D. I., 2008.

Research output: Contribution to ConferencePosterOther research output

Collaborative projects making use of the MDD – GAIN data

Hottenga, J. J., Willemsen, G., Vink, J. M., Posthuma, D., de Moor, M. H. M., Ligthart, R. S. L., Smit, D. J. A., de Geus, E. J. C. & Boomsma, D. I., 2008.

Research output: Contribution to ConferencePosterOther research output

Design and implementation of a twin-family database for behavior genetics and genomics studies.

Boomsma, D. I., Willemsen, G., Vink, J. M., Bartels, M., Groot, P., Hottenga, J. J., van Beijsterveldt, C. E. M., Stroet, T. M., van Dijk, R., Wertheim, R., Visser, M. & van der Kleij, F., 2008, In : Twin Research and Human Genetics. 11, 3, p. 342-348

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Genetic Databases
Genomics
Pedigree
Databases
Information Storage and Retrieval

Genome Wide Association analysis for Borderline Personality Disorder Characteristics

Hottenga, J. J., Distel, M. A., Willemsen, G., Trull, T. J., Sullivan, P. F., de Geus, E. J. C. & Boomsma, D. I., 2008.

Research output: Contribution to ConferencePosterOther research output

Linkage on chromosome 14 in a genome-wide linkage study of a broad anxiety phenotype.

Middeldorp, C. M., Hottenga, J. J., Slagboom, P. E., Sullivan, P. F., de Geus, E. J. C., Posthuma, D., Willemsen, G. & Boomsma, D. I., 2008, In : Molecular Psychiatry. 13, 1, p. 84-89

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Chromosomes, Human, Pair 14
Anxiety
Genome
Phenotype
Anxiety Disorders

Smoking initiation and persistence: First results for genome-wide association analyses in Dutch adults

Vink, J. M., Sullivan, P. F., Smit, J. A., Hoogendijk, W. J. G., Hottenga, J. J., Willemsen, G., de Geus, E. J. C., Penninx, B. W. J. H. & Boomsma, D. I., 2008.

Research output: Contribution to ConferencePosterOther research output

Smoking initiation and persistence: First results for genome-wide association analyses in Dutch adults.

Boomsma, D. I., Vink, J. M., Sullivan, P. F., Smit, J. H., Hoogendijk, W. J. G., Hottenga, J. J., Willemsen, G., de Geus, E. J. C. & Penninx, B. W. J. H., 2008, In : Behavior Genetics. 38, p. 615-616

Research output: Contribution to JournalMeeting AbstractOther research output

Vitamin D receptor gene polymorphisms have negligible effect on human height.

Macgregor, S., Hottenga, J. J., Lind, P. A., Suchiman, E., Willemsen, G., Slagboom, P. E., Montgomery, GW., Martin, N. G., Visscher, P. M. & Boomsma, D. I., 2008, In : Twin Research and Human Genetics. 11, 5, p. 488-494

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Calcitriol Receptors
Meta-Analysis
Genes
Physiological Phenomena
Vitamin D
2007

Combined genome scans for body stature in 6,602 European twins: Evidence for common Caucasian loci.

Perola, M., Sammalisto, S., Hiekkalinna, T., Martin, N. G., Visscher, P. M., Montgomery, GW., Benyamin, B., Harris, J. R., Boomsma, D. I., Willemsen, G., Hottenga, J. J., Christensen, K., Kyvik, K., Sorensen, T. I. A., Pedersen, N. L., Magnusson, P. K. E., Spector, T. D., Widen, E., Silventoinen, K., Kaprio, J. & 2 othersPalotie, A. & Peltonen, L., 2007, In : PLoS Genetics. 3, 6, 10 p., e97.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Quantitative Trait Loci
Software
genome
Genome
Chromosomes, Human, Pair 20

Family based association analyses between the Serotonin Transporter Gene Polymorphism (5-HTTLPR) and Neuroticism, Anxiety and Depression

Middeldorp, C. M., de Geus, E. J. C., Beem, A. L., Lakenberg, N., Hottenga, J. J., Slagboom, P. E. & Boomsma, D. I., 2007, In : Behavior Genetics. 37, 2, p. 294-301

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Serotonin Plasma Membrane Transport Proteins
anxiety
serotonin
transporters
polymorphism

Genome-wide linkage scan for athlete status in 700 British female DZ twin pairs

de Moor, M. H. M., Spector, T. D., Cherkas, L. F., Falchi, M., Hottenga, J. J., Boomsma, D. I. & de Geus, E. J. C., 2007, In : Twin Research and Human Genetics. 10, 6, p. 812-820

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Dizygotic Twins
Athletes
Genome
Genes
Single Nucleotide Polymorphism
Open Access
File
Genome
Chromosomes
Metabolic Equivalent
Genes
Muscles

Genome-wide scan for blood pressure in Australian and Dutch subjects suggests linkage at 5P, 14Q and 17P.

Hottenga, J. J., Whitfield, J. B., Posthuma, D., Willemsen, A. H. M., de Geus, E. J. C., Martin, N. G. & Boomsma, D. I., 2007, In : Hypertension. 49, 4, p. 832-838

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Genome
Blood Pressure
Chromosomes
Dizygotic Twins
Netherlands

Heritability of head size in Dutch and Australian twin families at ages 5–50 years

Boomsma, D. I., Bartels, M., van Beijsterveldt, C. E. M., Luciano, M., de Geus, E. J. C., Posthuma, D., Hottenga, J. J., Hoekstra, R. A., van Burk-Estourgie, G. F., Delemarre-van de Waal, H. A. & Martin, N. G., 2007, In : Behavior Genetics. 37, p. 740-741

Research output: Contribution to JournalMeeting AbstractOther research output

Is PLXNA2 a candidate gene for childhood and adult anxiety and depression?

Boomsma, D. I., Middeldorp, C. M., Hottenga, J. J., de Geus, E. J. C., Willemsen, G., Bartels, M., Hudziak, J., Slof-Op 't Landt, M. C. T., Meulenbelt, I., Suchiman, E. & Slagboom, P. E., 2007, In : American Journal of Human Genetics.

Research output: Contribution to JournalMeeting AbstractOther research output

The vitamin D receptor gene is not strongly associated with stature: Results from The Netherlands Twin Register

Hottenga, J. J., Suchiman, E., Willemsen, G., Slagboom, P. E. & Boomsma, D. I., 2007, In : Behavior Genetics. 37, p. 763

Research output: Contribution to JournalMeeting AbstractOther research output

2006

Assortative mating for obsessive-compulsive behavior in a population-based sample.

van Grootheest, D. S., van den Berg, S. M., Hottenga, J. J., Cath, D. C. & Boomsma, D. I., 2006, In : American Journal of Human Genetics. 141B, p. 739

Research output: Contribution to JournalMeeting AbstractOther research output

Combined Linkage and Association Analyses of the 124-bp Allele of Marker D2S2944 with Anxiety, Depression, Neuroticism and Major Depression

Beem, A. L., de Geus, E. J. C., Hottenga, J. J., Sullivan, P. F., Willemsen, G., Slagboom, P. E. & Boomsma, D. I., 2006, In : Behavior Genetics. 36, 1, p. 127-136

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
anxiety
linkage (genetics)
allele
Anxiety
Alleles

Empirical evaluation of the genetic similarity of samples from twin registries in Australia and the Netherlands using 359 STRP markers

Sullivan, P. F., Montgomery, GW., Hottenga, J. J., Wray, N. R., Boomsma, D. I. & Martin, N. G., 2006, In : Twin Research and Human Genetics. 9, 4, p. 600-602

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File

Heritability and stability of resting blood pressure in Australian twins

Hottenga, J. J., Whitfield, J. B., de Geus, J. C. N., Boomsma, D. I. & Martin, N. G., 2006, In : Twin Research and Human Genetics. 9, 2, p. 205-209

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Blood Pressure
Dizygotic Twins
Multivariate Analysis

HLA and genome wide allele sharing in dizygotic twins.

Montgomery, GW., Zhu, G., Hottenga, J. J., Duffy, DL., Heath, A. C., Boomsma, D. I., Martin, N. G. & Visscher, P. M., 2006, In : American Journal of Human Genetics. 79, 6, p. 1052-1058

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Dizygotic Twins
Alleles
Genome
Siblings
Embryonic Structures

Netherlands Twin Register: From twins to twin families.

Boomsma, D. I., de Geus, E. J. C., Vink, J. M., Stubbe, J. H., Distel, M. A., Hottenga, J. J., Posthuma, D., van Beijsterveldt, C. E. M., Hudziak, J., Bartels, M. & Willemsen, G., 2006, In : Twin Research and Human Genetics. 9, 6, p. 849-857

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Netherlands
Young Adult
Siblings
Longitudinal Studies
Databases

Significant linkage on chromosome 14 for anxiety.

Middeldorp, C. M., Hottenga, J. J., Slagboom, P. E., Sullivan, P. F., Beem, A. L., Willemsen, G. & Boomsma, D. I., 2006, In : American Journal of Human Genetics. 141B, p. 725

Research output: Contribution to JournalMeeting AbstractOther research output

2005

Genetic association tests of RGS genes on chromosome 1q for depression and correlated traits in the Netherlands Twin-family Study of Anxious Depression (NETSAD)

Boomsma, D. I., Beem, A. L., Willemsen, A. H. M., Hottenga, J. J., de Geus, J. C. N., Middeldorp, C. M., Sullivan, P. F., Suchiman, E., Lakenberg, N. & Slagboom, P. E., 2005, In : Behavior Genetics. 35, 6, p. 794-795

Research output: Contribution to JournalMeeting AbstractOther research output

Heritability and stability of resting blood pressure

Hottenga, J. J., 2005.

Research output: Contribution to ConferencePosterOther research output

Heritability and stability of resting blood pressure

Hottenga, J. J., Boomsma, D. I., Kupper, H. M., Posthuma, D., Snieder, H., Willemsen, G. & de Geus, J. C. N., 2005, In : Twin Research and Human Genetics. 8, 5, p. 499-508

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Blood Pressure
Dizygotic Twins
Ambulatory Monitoring
Twin Studies
Monozygotic Twins
2004

Can the comorbidity of physical inactivity and cardiovascular risk factors help us find genes?

de Geus, E. J. C., Willemsen, A. H. M., Posthuma, D., Hottenga, J. J., Kupper, H. M., Stubbe, J. H., Vink, J. M. & Boomsma, D. I., 2004, In : Twin Research. 7, 6, p. 682

Research output: Contribution to JournalMeeting AbstractOther research output

Genetic contribution to blood pressure: heritability and linkage results from Dutch twin and sibling pairs.

Hottenga, J. J., de Geus, E. J. C., Willemsen, A. H. M., Snieder, H., Kupper, H. M., van den Berg, M., Beem, A. L., Heijmans, B. T., Beekman, M., Slagboom, P. E., Posthuma, D. & Boomsma, D. I., 2004, In : Genetic Epidemiology. 27, 3, p. 275

Research output: Contribution to JournalMeeting AbstractOther research output