If you made any changes in Pure these will be visible here soon.

Research Output 2004 2020

2018

Genome-wide analysis of DNA methylation in buccal cells: A study of monozygotic twins and mQTLs

Van Dongen, J., Ehli, E. A., Jansen, R., Van Beijsterveldt, C. E. M., Willemsen, G., Hottenga, J. J., Kallsen, N. A., Peyton, S. A., Breeze, C. E., Kluft, C., Heijmans, B. T., Bartels, M., Davies, G. E. & Boomsma, D. I., 25 Sep 2018, In : Epigenetics and Chromatin. 11, p. 1-14 14 p., 54.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Monozygotic Twins
Cheek
DNA Methylation
Methylation
Quantitative Trait Loci

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N. & 30 othersCastelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., DIrek, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Eriksson, N., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M. G., Posthuma, D., Smit, J. H., Willemsen, G., Boomsma, D. I. & Penninx, B. W. J. H., May 2018, In : Nature Genetics. 50, 5, p. 668-681 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Genome-Wide Association Study
Depression
Schizophrenia
Major Depressive Disorder
Suicide

Genome-wide association analysis links multiple psychiatric liability genes to oscillatory brain activity

Smit, D. J. A., Wright, M. J., Meyers, J. L., Martin, N. G., Ho, Y. Y. W., Malone, S. M., Zhang, J., Burwell, S. J., Chorlian, D. B., de Geus, E. J. C., Denys, D., Hansell, N. K., Hottenga, J. J., McGue, M., van Beijsterveldt, C. E. M., Jahanshad, N., Thompson, P. M., Whelan, C. D., Medland, S. E., Porjesz, B. & 2 othersLacono, W. G. & Boomsma, D. I., Nov 2018, In : Human Brain Mapping. 39, 11, p. 4183-4195 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Genome-Wide Association Study
Psychiatry
Brain
Genes
Psychopathology
Genome-Wide Association Study
Cannabis
Meta-Analysis
Single Nucleotide Polymorphism
Calcium Signaling

Genome-wide association meta-analysis of age at first cannabis use

Minică, C. C., Verweij, K. J. H., van der Most, P. J., Mbarek, H., Bernard, M., van Eijk, K. R., Lind, P. A., Liu, M. Z., Maciejewski, D. F., Palviainen, T., Sánchez-Mora, C., Sherva, R., Taylor, M., Walters, R. K., Abdellaoui, A., Bigdeli, T. B., Branje, S. J. T., Brown, S. A., Casas, M., Corley, R. P. & 50 othersDavey-Smith, G., Davies, G. E., Ehli, E. A., Farrer, L., Fedko, I. O., Garcia-Martínez, I., Gordon, S. D., Hartman, C. A., Heath, A. C., Hickie, I. B., Hickman, M., Hopfer, C. J., Hottenga, J. J., Kahn, R. S., Kaprio, J., Korhonen, T., Kranzler, H. R., Krauter, K., van Lier, P. A. C., Madden, P. A. F., Medland, S. E., Neale, M. C., Meeus, W. H. J., Montgomery, G. W., Nolte, I. M., Oldehinkel, A. J., Pausova, Z., Ramos-Quiroga, J. A., Richarte, V., Rose, R. J., Shin, J., Stallings, M. C., Wall, T. L., Ware, J. J., Wright, M. J., Zhao, H., Koot, H. M., Paus, T., Hewitt, J. K., Ribasés, M., Loukola, A., Boks, M. P., Snieder, H., Munafò, M. R., Gelernter, J., Boomsma, D. I., Martin, N. G., Gillespie, N. A., Vink, J. M. & Derks, E. M., Nov 2018, In : Addiction. 113, 11, p. 2073-2086 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-Wide Association Study
Cannabis
Meta-Analysis
Single Nucleotide Polymorphism
Calcium Signaling
Hair Color
Genome-Wide Association Study
Hair
Meta-Analysis
Melanins

Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability

Hysi, P. G., Valdes, A. M., Liu, F., Furlotte, N. A., Evans, D. M., Bataille, V., Visconti, A., Hemani, G., McMahon, G., Ring, S. M., Smith, G. D., Duffy, D. L., Zhu, G., Gordon, S. D., Medland, S. E., Lin, B. D., Willemsen, G., Hottenga, J. J., Vuckovic, D., Girotto, G. & 24 othersGandin, I., Sala, C., Concas, M. P., Brumat, M., Gasparini, P., Toniolo, D., Cocca, M., Robino, A., Yazar, S., Hewitt, A. W., Chen, Y., Zeng, C., Uitterlinden, A. G., Ikram, M. A., Hamer, M. A., Van Duijn, C. M., Nijsten, T., MacKey, D. A., Falchi, M., Boomsma, D. I., Martin, N. G., Hinds, D. A., Kayser, M. & Spector, T. D., May 2018, In : Nature Genetics. 50, 5, p. 652-656 5 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Hair Color
Genome-Wide Association Study
Hair
Meta-Analysis
Melanins

Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

Beaumont, R. N., Warrington, N. M., Cavadino, A., Tyrrell, J., Nodzenski, M., Horikoshi, M., Geller, F., Myhre, R., Richmond, R. C., Paternoster, L., Bradfield, J. P., Kreiner-Møller, E., Huikari, V., Metrustry, S., Lunetta, K. L., Painter, J. N., Hottenga, J-J., Allard, C., Barton, S. J., Espinosa, A. & 31 othersMarsh, J. A., Potter, C., Zhang, G., Ang, W., Berry, D. J., Bouchard, L., Das, S., Hakonarson, H., Heikkinen, J., Helgeland, Ø., Hocher, B., Hofman, A., Inskip, H. M., Jones, S. E., Kogevinas, M., Lind, P. A., Marullo, L., Medland, S. E., Murray, A., Murray, J. C., Njølstad, P. R., Nohr, E. A., Reichetzeder, C., Ring, S. M., Ruth, K. S., Santa-Marina, L., Scholtens, D. M., Willemsen, G., Bartels, M., Boomsma, D. I. & Early Growth Genetics (EGG) Consortium, 1 Feb 2018, In : Human Molecular Genetics. 27, 4, p. 742-756

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Genome-Wide Association Study
Birth Weight
Mothers
Fetal Development
Single Nucleotide Polymorphism

Genome-wide identification of directed gene networks using large-scale population genomics data

BIOS (Biobank-based Integrative Omics Study) Consortium, 6 Aug 2018, In : Nature Communications. 9, p. 1-10 10 p., 3097.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Metagenomics
genome
Gene Regulatory Networks
genes
Genes

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Generation Scotland & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 20 Dec 2018, In : PLoS ONE. 13, 12, p. 1-29 29 p., e0209160.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Major Depressive Disorder
Proxy
Genes
Genome
genome

Genome-wide meta-analysis of cognitive empathy: Heritability, and correlates with sex, neuropsychiatric conditions and cognition

Warrier, V., Grasby, K. L., Uzefovsky, F., Toro, R., Smith, P., Chakrabarti, B., Khadake, J., Mawbey-Adamson, E., Litterman, N., Hottenga, J. J., Lubke, G., Boomsma, D. I., Martin, N. G., Hatemi, P. K., Medland, S. E., Hinds, D. A., Bourgeron, T. & Baron-Cohen, S., 6 Jun 2018, In : Molecular Psychiatry. 23, p. 1402-1409 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Cognition
Meta-Analysis
Genome
Volunteers
Twin Studies

Molecular genetic overlap between migraine and major depressive disorder

The International Headache Genetics Consortium, 1 Aug 2018, In : European Journal of Human Genetics. 26, 8, p. 1202-1216 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Major Depressive Disorder
Migraine Disorders
Molecular Biology
Single Nucleotide Polymorphism
Genome-Wide Association Study

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

Demenais, F., Margaritte-Jeannin, P., Barnes, K. C., Cookson, W. O. C., Altmüller, J., Ang, W., Barr, R. G., Beaty, T. H., Becker, A. B., Beilby, J., Bisgaard, H., Bjornsdottir, U. S., Bleecker, E., Bønnelykke, K., Boomsma, D. I., Bouzigon, E., Brightling, C. E., Brossard, M., Brusselle, G. G., Burchard, E. & 31 othersBurkart, K. M., Bush, A., Chan-Yeung, M., Chung, K. F., Couto Alves, A., Curtin, J. A., Custovic, A., Daley, D., de Jongste, J. C., Del-Rio-Navarro, B. E., Donohue, K. M., Duijts, L., Eng, C., Eriksson, J. G., Farrall, M., Fedorova, Y., Feenstra, B., Ferreira, M. A., Freidin, M. B., Gajdos, Z., Gauderman, J., Gehring, U., Geller, F., Genuneit, J., Gharib, S. A., Gilliland, F., Heckbert, S. R., Hottenga, J., Mbarek, H., Willemsen, G. & Australian Asthma Genetics Consortium (AAGC) collaborators, Jan 2018, In : Nature Genetics. 50, 1, p. 42-53 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Asthma
Seasonal Allergic Rhinitis
Genome-Wide Association Study
Autoimmune Diseases
Meta-Analysis

Polygenic prediction of obsessive compulsive symptoms

Rodrigues Zilhao Nogueira, N., Abdellaoui, A., Smit, D. J. A., Cath, D. C., Hottenga, J. J. & Boomsma, D. I., 1 Feb 2018, In : Molecular Psychiatry. 23, 2, p. 168-169

Research output: Contribution to JournalArticleAcademicpeer-review

Polygenic risk for alcohol consumption and its association with alcohol-related phenotypes: Do stress and life satisfaction moderate these relationships?

Mies, G. W., Verweij, K. J. H., Treur, J. L., Ligthart, L., Fedko, I. O., Hottenga, J. J., Willemsen, G., Bartels, M., Boomsma, D. I. & Vink, J. M., 1 Jan 2018, In : Drug and Alcohol Dependence. 183, p. 7-12 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Psychological Stress
Alcohol Drinking
Alcohols
Phenotype
Drinking Behavior

Predicting loneliness with polygenic scores of social, psychological and psychiatric traits

Abdellaoui, A., Nivard, M. G., Hottenga, J. J., Fedko, I., Verweij, K. J. H., Baselmans, B. M. L., Ehli, E. A., Davies, G. E., Bartels, M., Boomsma, D. I. & Cacioppo, J. T., Jul 2018, In : Genes, Brain and Behavior. 17, 6, p. 1-10 10 p., e12472.

Research output: Contribution to JournalArticleAcademicpeer-review

Community Psychiatry
Loneliness
Psychology
Mental Health
Schizophrenia

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

the Million Veteran Program, Dec 2018, In : Nature Genetics. 50, 12, p. 1755-1755 1 p.

Research output: Contribution to JournalErratumAcademic

Testing familial transmission of smoking with two different research designs

Treur, J. L., Verweij, K. J. H., Abdellaoui, A., Fedko, I. O., de Zeeuw, E. L., Ehli, E. A., Davies, G. E., Hottenga, J. J., Willemsen, G., Boomsma, D. I. & Vink, J. M., 7 Jun 2018, In : Nicotine and Tobacco Research. 20, 7, p. 836-842 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Research Design
Smoking
Gene-Environment Interaction
Twin Studies
Netherlands
2019
Phenotype
phenotype
Loneliness
Health
genetic correlation

A Genetic Investigation of the Well-Being Spectrum

Baselmans, B. M. L., van de Weijer, M. P., Abdellaoui, A., Vink, J. M., Hottenga, J. J., Willemsen, G., Nivard, M. G., de Geus, E. J. C., Boomsma, D. I. & Bartels, M., 15 May 2019, In : Behavior Genetics. 49, 3, p. 286-297 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Phenotype
phenotype
Loneliness
Health
genetic correlation

A linear mixed-model approach to study multivariate gene-environment interactions

't Hoen, P. A., van Meurs, J. B. J., Isaacs, A., Jansen, R., Franke, L., Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J., Van Greevenbroek, M. J., Stehouwer, C. D. A., van der Kallen, C. J. H., Schalkwijk, C. G., Wijmenga, C., Zhernakova, A., Tigchelaar, E. F., Slagboom, P. E., Beekman, M., Deelen, J., van Heemst, D. & 30 othersVeldink, J. H., van den Berg, L. H., van Duijn, C. M., Hofman, B. A., Uitterlinden, A. G., Jhamai, P. M., Verbiest, M., Suchiman, H. E. D., Verkerk, M., van der Breggen, R., van Rooij, J., Lakenberg, N., Mei, H., van Iterson, M., van Galen, M., Bot, J., van’t Hof, P., Deelen, P., Nooren, I., Moed, M., Vermaat, M., Zhernakova, D. V., Luijk, R., Jan Bonder, M., van Dijk, F., Arindrarto, W., Kielbasa, P. S. M., Swertz, M. A., van Zwet, E. W. & BIOS Consortium, Jan 2019, In : Nature Genetics. 51, 1, p. 180-186 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Gene-Environment Interaction
Linear Models
Genotype
Body Mass Index
Diet

A Potential Role for the STXBP5-AS1 Gene in Adult ADHD Symptoms

The EAGLE-ADHD Consortium, 18 Jan 2019, In : Behavior Genetics. p. 1-16 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Impulsive Behavior
Single Nucleotide Polymorphism
Meta-Analysis
signs and symptoms (animals and humans)
meta-analysis

Association between rs1051730 and smoking during pregnancy in Dutch women

Mbarek, H., van Beijsterveldt, C. E. M., Hottenga, J. J., Dolan, C. V., Boomsma, D. I., Willemsen, G. & Vink, J. M., Jun 2019, In : Nicotine and Tobacco Research. 21, 6, p. 835-840 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Smoking
Pregnancy
Pregnant Women
Parturition
Smoking Cessation

Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition

Writing Committee for the ENIGMA-CNV Working Group , 30 Oct 2019, In : JAMA Psychiatry. p. 1-11 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Cognition
Aptitude
Brain
Iceland
Parietal Lobe

Association of Whole-Genome and NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M. G., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. JC., W J H Penninx, B., Jansen, R. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jan 2019, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Major Depressive Disorder
Anisotropy
Genome
Radiation
Diffusion Tensor Imaging

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

23Andme Research Team & HUNT All-In Psychiatry, Feb 2019, In : Nature Genetics. 51, 2, p. 237-244 8 p.

Research output: Contribution to JournalLetterAcademicpeer-review

Tobacco Use
Alcohols
Tobacco Use Cessation
Genetic Association Studies
Synaptic Transmission

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Derks, E. M., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M., Peyrot, W. J., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., W J H Penninx, B. & Sullivan, P., 11 Nov 2019, In : Molecular Psychiatry.

Research output: Contribution to JournalArticleAcademicpeer-review

Bipolar Disorder
Psychiatry
Schizophrenia
Depression
Major Depressive Disorder

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M., Peyrot, W. J., Posthuma, D. & Willemsen, G., 5 Aug 2019, In : Biological Psychiatry. p. 1-12 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
HLA Antigens
Haplotypes
Alleles
Depression
Major Histocompatibility Complex

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

Davies, G. E., Ehli, E. A., Fedko, I. O., Groen-Blokhuis, M. M., Hammerschlag, A. R., Hottenga, J. J., Hudziak, J., Ouwens, K. G. & ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Jan 2019, In : Nature Genetics. 51, 1, p. 63-75 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Attention Deficit Disorder with Hyperactivity
Genome
Genome-Wide Association Study
Meta-Analysis
Population

Genetic architecture of subcortical brain structures in 38,851 individuals

Satizabal, C. L., Adams, H. H. H., Hibar, D. P., White, C. C., Knol, M. J., Stein, J. L., Scholz, M., Sargurupremraj, M., Jahanshad, N., Roshchupkin, G. V., Smith, A. V., Bis, J. C., Jian, X., Luciano, M., Hofer, E., Teumer, A., van der Lee, S. J., Yang, J., Yanek, L. R., Lee, T. V. & 269 othersLi, S., Hu, Y., Koh, J. Y., Eicher, J. D., Desrivières, S., Arias-Vasquez, A., Chauhan, G., Athanasiu, L., Rentería, M. E., Kim, S., Hoehn, D., Armstrong, N. J., Chen, Q., Holmes, A. J., den Braber, A., Kloszewska, I., Andersson, M., Espeseth, T., Grimm, O., Abramovic, L., Alhusaini, S., Milaneschi, Y., Papmeyer, M., Axelsson, T., Ehrlich, S., Roiz-Santiañez, R., Kraemer, B., Håberg, A. K., Jones, H. J., Pike, G. B., Stein, D. J., Stevens, A., Bralten, J., Vernooij, M. W., Harris, T. B., Filippi, I., Witte, A. V., Guadalupe, T., Wittfeld, K., Mosley, T. H., Becker, J. T., Doan, N. T., Hagenaars, S. P., Saba, Y., Cuellar-Partida, G., Amin, N., Hilal, S., Nho, K., Mirza-Schreiber, N., Arfanakis, K., Becker, D. M., Ames, D., Goldman, A. L., Lee, P. H., Boomsma, D. I., Lovestone, S., Giddaluru, S., Le Hellard, S., Mattheisen, M., Bohlken, M. M., Kasperaviciute, D., Schmaal, L., Lawrie, S. M., Agartz, I., Walton, E., Tordesillas-Gutierrez, D., Davies, G. E., Shin, J., Ipser, J. C., Vinke, L. N., Hoogman, M., Jia, T., Burkhardt, R., Klein, M., Crivello, F., Janowitz, D., Carmichael, O., Haukvik, U. K., Aribisala, B. S., Schmidt, H., Strike, L. T., Cheng, C-Y., Risacher, S. L., Pütz, B., Fleischman, D. A., Assareh, A. A., Mattay, V. S., Buckner, R. L., Mecocci, P., Dale, A. M., Cichon, S., Boks, M. P., Matarin, M., Penninx, B. W. J. H., Calhoun, V. D., Chakravarty, M. M., Marquand, A. F., Macare, C., Kharabian Masouleh, S., Oosterlaan, J., Amouyel, P., Hegenscheid, K., Rotter, J. I., Schork, A. J., Liewald, D. C. M., de Zubicaray, G. I., Wong, T. Y., Shen, L., Sämann, P. G., Brodaty, H., Roffman, J. L., de Geus, E. J. C., Tsolaki, M., Erk, S., van Eijk, K. R., Cavalleri, G. L., van der Wee, N. J. A., McIntosh, A. M., Gollub, R. L., Bulayeva, K. B., Bernard, M., Richards, J. S., Himali, J. J., Loeffler, M., Rommelse, N., Hoffmann, W., Westlye, L. T., Valdés Hernández, M. C., Hansell, N. K., van Erp, T. G. M., Wolf, C., Kwok, J. B. J., Vellas, B., Heinz, A., Olde Loohuis, L. M., Delanty, N., Ho, B-C., Ching, C. R. K., Shumskaya, E., Singh, B., Hofman, A., van der Meer, D., Homuth, G., Psaty, B. M., Bastin, M. E., Montgomery, G. W., Foroud, T. M., Reppermund, S., Hottenga, J-J., Simmons, A., Meyer-Lindenberg, A., Cahn, W., Whelan, C. D., van Donkelaar, M. M. J., Yang, Q., Hosten, N., Green, R. C., Thalamuthu, A., Mohnke, S., Hulshoff Pol, H. E., Lin, H., Jack, C. R., Schofield, P. R., Mühleisen, T. W., Maillard, P., Potkin, S. G., Wen, W., Fletcher, E., Toga, A. W., Gruber, O., Huentelman, M., Davey Smith, G., Launer, L. J., Nyberg, L., Jönsson, E. G., Crespo-Facorro, B., Koen, N., Greve, D. N., Uitterlinden, A. G., Weinberger, D. R., Steen, V. M., Fedko, I. O., Groenewold, N. A., Niessen, W. J., Toro, R., Tzourio, C., Longstreth, W. T., Ikram, M. K., Smoller, J. W., van Tol, M-J., Sussmann, J. E., Paus, T., Lemaître, H., Schroeter, M. L., Mazoyer, B., Andreassen, O. A., Holsboer, F., Depondt, C., Veltman, D. J., Turner, J. A., Pausova, Z., Schumann, G., van Rooij, D., Djurovic, S., Deary, I. J., McMahon, K. L., Müller-Myhsok, B., Brouwer, R. M., Soininen, H., Pandolfo, M., Wassink, T. H., Cheung, J. W., Wolfers, T., Martinot, J-L., Zwiers, M. P., Nauck, M., Melle, I., Martin, N. G., Kanai, R., Westman, E., Kahn, R. S., Sisodiya, S. M., White, T., Saremi, A., van Bokhoven, H., Brunner, H. G., Völzke, H., Wright, M. J., van 't Ent, D., Nöthen, M. M., Ophoff, R. A., Buitelaar, J. K., Fernández, G., Sachdev, P. S., Rietschel, M., van Haren, N. E. M., Fisher, S. E., Beiser, A. S., Francks, C., Saykin, A. J., Mather, K. A., Romanczuk-Seiferth, N., Hartman, C. A., DeStefano, A. L., Heslenfeld, D. J., Weiner, M. W., Walter, H., Hoekstra, P. J., Nyquist, P. A., Franke, B., Bennett, D. A., Grabe, H. J., Johnson, A. D., Chen, C., van Duijn, C. M., Lopez, O. L., Fornage, M., Wardlaw, J. M., Schmidt, R., DeCarli, C., De Jager, P. L., Villringer, A., Debette, S., Gudnason, V., Medland, S. E., Shulman, J. M., Thompson, P. M., Seshadri, S. & Ikram, M. A., Nov 2019, In : Nature Genetics. 51, 11, p. 1624-1636 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Axonal Transport
Globus Pallidus
Caudate Nucleus
Genome-Wide Association Study
Putamen

Genetic meta-analysis of obsessive-compulsive disorder and self-report compulsive symptoms

Smit, D. J. A., Cath, D., Zilhão, N. R., Ip, H. F., Denys, D., den Braber, A., de Geus, E. J. C., Verweij, K. J. H., Hottenga, J-J. & Boomsma, D. I., 31 Dec 2019, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics.

Research output: Contribution to JournalArticleAcademicpeer-review

Obsessive-Compulsive Disorder
Self Report
Meta-Analysis
Genome-Wide Association Study
Genes

Genetic Similarity Assessment of Twin-Family Populations by Custom-Designed Genotyping Array

Beck, J. J., Hottenga, J. J., Mbarek, H., Finnicum, C. T., Ehli, E. A., Hur, Y-M., Martin, N. G., de Geus, E. J. C., Boomsma, D. I. & Davies, G. E., Aug 2019, In : Twin research and human genetics : the official journal of the International Society for Twin Studies. 22, 4, p. 210-219 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Population
Netherlands
Genome-Wide Association Study
Nigeria
Genotype

Genetic Vulnerability for Smoking and Cannabis Use: Associations With E-Cigarette and Water Pipe Use

International Cannabis Consortium, 21 May 2019, In : Nicotine and Tobacco Research. 21, 6, p. 723-730 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Marijuana Smoking
Smoking
Water
Cannabis
Phenotype
Genetic Loci
Genome-Wide Association Study
Single Nucleotide Polymorphism
Computational Biology
Synaptic Transmission

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Social Science Genetic Association Consortium, 23and Me Research Team, eQTLGen Consortium & International Cannabis Consortium, 1 Feb 2019, In : Nature Genetics. 51, 2, p. 245-257 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Genetic Loci
Genome-Wide Association Study
Single Nucleotide Polymorphism
Computational Biology
Synaptic Transmission

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

van Setten, J., Verweij, N., Mbarek, H., Niemeijer, M. N., Trompet, S., Arking, D. E., Brody, J. A., Gandin, I., Grarup, N., Hall, L. M., Hemerich, D., Lyytikäinen, L. P., Mei, H., Müller-Nurasyid, M., Prins, B. P., Robino, A., Smith, A. V., Warren, H. R., Asselbergs, F. W., Boomsma, D. I. & 41 othersCaulfield, M. J., Eijgelsheim, M., Ford, I., Hansen, T., Harris, T. B., Heckbert, S. R., Hottenga, J. J., Iorio, A., Kors, J. A., Linneberg, A., MacFarlane, P. W., Meitinger, T., Nelson, C. P., Raitakari, O. T., Silva Aldana, C. T., Sinagra, G., Sinner, M., Soliman, E. Z., Stoll, M., Uitterlinden, A., van Duijn, C. M., Waldenberger, M., Alonso, A., Gasparini, P., Gudnason, V., Jamshidi, Y., Kääb, S., Kanters, J. K., Lehtimäki, T., Munroe, P. B., Peters, A., Samani, N. J., Sotoodehnia, N., Ulivi, S., Wilson, J. G., de Geus, E. J. C., Jukema, J. W., Stricker, B., van der Harst, P., de Bakker, P. I. W. & Isaacs, A., Jun 2019, In : European Journal of Human Genetics. 27, 6, p. 952-962 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Quantitative Trait Loci
Genome-Wide Association Study
Single Nucleotide Polymorphism
Meta-Analysis
Genome

Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts

Zhang, X., Abdellaoui, A., Rucker, J., de Jong, S., Potash, J. B., Weissman, M. M., Shi, J., Knowles, J. A., Pato, C., Pato, M., Sobell, J., Smit, J. H., Hottenga, J. J., de Geus, E. J. C., Lewis, C. M., Buttenschøn, H. N., Craddock, N., Jones, I., Jones, L., McGuffin, P. & 13 othersMors, O., Owen, M. J., Preisig, M., Rietschel, M., Rice, J. P., Rivera, M., Uher, R., Gejman, P. V., Sanders, A. R., Boomsma, D., Penninx, B. W. J. H., Breen, G. & Levinson, D. F., 15 Jun 2019, In : Biological Psychiatry. 85, 12, p. 1065-1073 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Major Depressive Disorder
Genome
Intergenic DNA
Nucleic Acid Regulatory Sequences
Genome-Wide Association Study

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee, P. H., Anttila, V., Won, H., Feng, Y., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M., Grotzinger, A. D., Posthuma, D., Derks, E. M., op Landt Slof, M. C. T., Boomsma, D. I., de Geus, E. J. C., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., W J H Penninx, B., Cath, D. C. & 11 othersDenys, D., Santangelo, S., Scharf, J. M., Stein, M. B., Thornton, L. M., Walters, J. T. R., Wray, N. R., Geschwind, D. H., Neale, B. M., Kendler, K. S. & Smoller, J. W., 12 Dec 2019, In : Cell. 179, 7, p. 1469-1482.e11

Research output: Contribution to JournalArticleAcademicpeer-review

Psychiatry
Genes
Tourette Syndrome
Obsessive-Compulsive Disorder
Anorexia Nervosa

Identification of common genetic risk variants for autism spectrum disorder

Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, BUPGEN, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23Andme Research Team, Mar 2019, In : Nature Genetics. 51, 3, p. 431-444 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Genome-Wide Association Study
Phenotype
Sample Size
Meta-Analysis
Autism Spectrum Disorder

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 11 Jun 2019, In : Nature Communications. 10, p. 1-18 18 p., 2548.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
methylation
DNA Methylation
Fetal Blood
blood
Blood
Birth Weight
Mothers
Blood Pressure
Alleles
Genome-Wide Association Study

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

EGG Consortium, 1 May 2019, In : Nature Genetics. 51, 5, p. 804-814 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Birth Weight
Mothers
Blood Pressure
Alleles
Genome-Wide Association Study

Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

eQTLGen Consortium, BIOS Consortium, Boomsma, D. I., Nivard, M., Hottenga, J. J., Pool, R. & van Dongen, J., 24 Jul 2019, In : Nature Communications. 10, 1, 3300.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
genome
Genome-Wide Association Study
Random Allocation
determinants
Genes

Multivariate genome-wide analyses of the well-being spectrum

BIOS Consortium, Mar 2019, In : Nature Genetics. 51, 3, p. 445-451 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-Wide Association Study
Genome
Meta-Analysis
Interneurons
Computational Biology

Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness

23Andme Research Team, 15 Nov 2019, In : Human Molecular Genetics. 28, 22, p. 3853-3865 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Loneliness
Genetic Predisposition to Disease
Health
Mendelian Randomization Analysis
Mental Health

Skewed X-inactivation is common in the general female population

Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J., Willemsen, G. & BIOS Consortium, Mar 2019, In : European Journal of Human Genetics. 27, 3, p. 455-465 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
X Chromosome Inactivation
X Chromosome
Population
Genes
Alleles

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

EArly Genetics Lifecourse Epidemiology (EAGLE) consortium & Early Growth Genetics (EGG) Consortium, Mar 2019, In : European Journal of Epidemiology. 34, 3, p. 279-300

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Molecular Epidemiology
Sample Size
Genetic Research
Low Birth Weight Infant
Atopic Dermatitis

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A., Derks, E. M., Dolan, C. V., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M., Peyrot, W. J., Willemsen, G., Boomsma, D. I., de Geus, E. J. C., W J H Penninx, B. & Posthuma, D., 1 Nov 2019, In : Biological Psychiatry.

Research output: Contribution to JournalArticleAcademicpeer-review

Inborn Genetic Diseases
Genome-Wide Association Study
Mood Disorders
Bipolar Disorder
Major Depressive Disorder
Open Access
Educational Status
Social Class
Netherlands
Genetic Structures