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2018

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium

Peyrot, W. J., Van der Auwera, S., Milaneschi, Y., Dolan, C. V., Madden, P. A. F., Sullivan, P. F., Strohmaier, J., Ripke, S., Rietschel, M., Nivard, M. G., Mullins, N., Montgomery, G. W., Henders, A. K., Heat, A. C., Fisher, H. L., Dunn, E. C., Byrne, E. M., Air, T. A., Baune, B. T., Breen, G. & 10 others, Levinson, D. F., Lewis, C. M., Martin, N. G., Nelson, E. N., Boomsma, D. I., Grabe, H. J., Wray, N. R., Penninx, B. W. J. H., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & Hottenga, J. J., 1 Jul 2018, In : Biological Psychiatry. 84, 2, p. 138-147 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Establishing a Twin Register: An Invaluable Resource for (Behavior) Genetic, Epidemiological, Biomarker, and 'Omics' Studies

Odintsova, V. V., Willemsen, G., Dolan, C. V., Hottenga, J. J., Martin, N. G., Slagboom, P. E., Ordoñana, J. R. & Boomsma, D. I., Jun 2018, In : Twin Research and Human Genetics. 21, 3, p. 239-252 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

F251. Psychiatric Liability Genes are Linked to Oscillatory Brain Activity: A Genome-Wide Association Study

Smit, D., Wright, M., Meyers, J., Martin, N., Ho, Y., Malone, S., Zhang, J., Burwell, S., Chorlian, D., de Geus, E., Denys, D., Hansell, N., Hottenga, J-J., McGue, M., van Beijsterveldt, C., Jehanshad, N., Thompson, P., Whelan, C., Medland, S., Porjesz, B. & 2 others, Iacono, W. & Boomsma, D., May 2018, In : Biological Psychiatry. 83, 9, p. S336

Research output: Contribution to JournalArticleAcademic

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

23Andme Research Team, Abdellaoui, A., Peyrot, W. J., Hottenga, J. J., Vinkhuyzen, A. A. E., Willemsen, G., Boomsma, D. I., van Duijn, C. M., Penninx, B., Posthuma, D. & Uitterlinden, A. G., Aug 2018, In : Nature Genetics. 50, 8, p. 1112-1121 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

the Million Veteran Program, Oct 2018, In : Nature Genetics. 50, 10, p. 1412-1431 20 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic vulnerability to schizophrenia is associated with cannabis use patterns during adolescence

Hiemstra, M., Nelemans, S. A., Branje, S., van Eijk, K. R., Hottenga, J. J., Vinkers, C. H., van Lier, P., Meeus, W. & Boks, M. P., 1 Sep 2018, In : Drug and Alcohol Dependence. 190, p. 143-150 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

LifeLines Cohort Study & CHARGE Inflammation Working Group, 1 Nov 2018, In : American Journal of Human Genetics. 103, 5, p. 691-706 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide analysis of DNA methylation in buccal cells: A study of monozygotic twins and mQTLs

Van Dongen, J., Ehli, E. A., Jansen, R., Van Beijsterveldt, C. E. M., Willemsen, G., Hottenga, J. J., Kallsen, N. A., Peyton, S. A., Breeze, C. E., Kluft, C., Heijmans, B. T., Bartels, M., Davies, G. E. & Boomsma, D. I., 25 Sep 2018, In : Epigenetics and Chromatin. 11, p. 1-14 14 p., 54.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N. & 30 others, Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., DIrek, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Eriksson, N., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M. G., Posthuma, D., Smit, J. H., Willemsen, G., Boomsma, D. I. & Penninx, B. W. J. H., May 2018, In : Nature Genetics. 50, 5, p. 668-681 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
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Genome-wide association analysis links multiple psychiatric liability genes to oscillatory brain activity

Smit, D. J. A., Wright, M. J., Meyers, J. L., Martin, N. G., Ho, Y. Y. W., Malone, S. M., Zhang, J., Burwell, S. J., Chorlian, D. B., de Geus, E. J. C., Denys, D., Hansell, N. K., Hottenga, J. J., McGue, M., van Beijsterveldt, C. E. M., Jahanshad, N., Thompson, P. M., Whelan, C. D., Medland, S. E., Porjesz, B. & 2 others, Lacono, W. G. & Boomsma, D. I., Nov 2018, In : Human Brain Mapping. 39, 11, p. 4183-4195 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide association meta-analysis of age at first cannabis use

Minică, C. C., Verweij, K. J. H., van der Most, P. J., Mbarek, H., Bernard, M., van Eijk, K. R., Lind, P. A., Liu, M. Z., Maciejewski, D. F., Palviainen, T., Sánchez-Mora, C., Sherva, R., Taylor, M., Walters, R. K., Abdellaoui, A., Bigdeli, T. B., Branje, S. J. T., Brown, S. A., Casas, M., Corley, R. P. & 50 others, Davey-Smith, G., Davies, G. E., Ehli, E. A., Farrer, L., Fedko, I. O., Garcia-Martínez, I., Gordon, S. D., Hartman, C. A., Heath, A. C., Hickie, I. B., Hickman, M., Hopfer, C. J., Hottenga, J. J., Kahn, R. S., Kaprio, J., Korhonen, T., Kranzler, H. R., Krauter, K., van Lier, P. A. C., Madden, P. A. F., Medland, S. E., Neale, M. C., Meeus, W. H. J., Montgomery, G. W., Nolte, I. M., Oldehinkel, A. J., Pausova, Z., Ramos-Quiroga, J. A., Richarte, V., Rose, R. J., Shin, J., Stallings, M. C., Wall, T. L., Ware, J. J., Wright, M. J., Zhao, H., Koot, H. M., Paus, T., Hewitt, J. K., Ribasés, M., Loukola, A., Boks, M. P., Snieder, H., Munafò, M. R., Gelernter, J., Boomsma, D. I., Martin, N. G., Gillespie, N. A., Vink, J. M. & Derks, E. M., Nov 2018, In : Addiction. 113, 11, p. 2073-2086 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability

Hysi, P. G., Valdes, A. M., Liu, F., Furlotte, N. A., Evans, D. M., Bataille, V., Visconti, A., Hemani, G., McMahon, G., Ring, S. M., Smith, G. D., Duffy, D. L., Zhu, G., Gordon, S. D., Medland, S. E., Lin, B. D., Willemsen, G., Hottenga, J. J., Vuckovic, D., Girotto, G. & 24 others, Gandin, I., Sala, C., Concas, M. P., Brumat, M., Gasparini, P., Toniolo, D., Cocca, M., Robino, A., Yazar, S., Hewitt, A. W., Chen, Y., Zeng, C., Uitterlinden, A. G., Ikram, M. A., Hamer, M. A., Van Duijn, C. M., Nijsten, T., MacKey, D. A., Falchi, M., Boomsma, D. I., Martin, N. G., Hinds, D. A., Kayser, M. & Spector, T. D., May 2018, In : Nature Genetics. 50, 5, p. 652-656 5 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

Beaumont, R. N., Warrington, N. M., Cavadino, A., Tyrrell, J., Nodzenski, M., Horikoshi, M., Geller, F., Myhre, R., Richmond, R. C., Paternoster, L., Bradfield, J. P., Kreiner-Møller, E., Huikari, V., Metrustry, S., Lunetta, K. L., Painter, J. N., Hottenga, J-J., Allard, C., Barton, S. J., Espinosa, A. & 31 others, Marsh, J. A., Potter, C., Zhang, G., Ang, W., Berry, D. J., Bouchard, L., Das, S., Hakonarson, H., Heikkinen, J., Helgeland, Ø., Hocher, B., Hofman, A., Inskip, H. M., Jones, S. E., Kogevinas, M., Lind, P. A., Marullo, L., Medland, S. E., Murray, A., Murray, J. C., Njølstad, P. R., Nohr, E. A., Reichetzeder, C., Ring, S. M., Ruth, K. S., Santa-Marina, L., Scholtens, D. M., Willemsen, G., Bartels, M., Boomsma, D. I. & Early Growth Genetics (EGG) Consortium, 1 Feb 2018, In : Human Molecular Genetics. 27, 4, p. 742-756 15 p., ddx429.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide identification of directed gene networks using large-scale population genomics data

BIOS (Biobank-based Integrative Omics Study) Consortium, 6 Aug 2018, In : Nature Communications. 9, p. 1-10 10 p., 3097.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Generation Scotland & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 20 Dec 2018, In : PLoS ONE. 13, 12, p. 1-29 29 p., e0209160.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide meta-analysis of cognitive empathy: Heritability, and correlates with sex, neuropsychiatric conditions and cognition

Warrier, V., Grasby, K. L., Uzefovsky, F., Toro, R., Smith, P., Chakrabarti, B., Khadake, J., Mawbey-Adamson, E., Litterman, N., Hottenga, J. J., Lubke, G., Boomsma, D. I., Martin, N. G., Hatemi, P. K., Medland, S. E., Hinds, D. A., Bourgeron, T. & Baron-Cohen, S., 6 Jun 2018, In : Molecular Psychiatry. 23, 6, p. 1402-1409 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Molecular genetic overlap between migraine and major depressive disorder

The International Headache Genetics Consortium, 1 Aug 2018, In : European Journal of Human Genetics. 26, 8, p. 1202-1216 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

Demenais, F., Margaritte-Jeannin, P., Barnes, K. C., Cookson, W. O. C., Altmüller, J., Ang, W., Barr, R. G., Beaty, T. H., Becker, A. B., Beilby, J., Bisgaard, H., Bjornsdottir, U. S., Bleecker, E., Bønnelykke, K., Boomsma, D. I., Bouzigon, E., Brightling, C. E., Brossard, M., Brusselle, G. G., Burchard, E. & 31 others, Burkart, K. M., Bush, A., Chan-Yeung, M., Chung, K. F., Couto Alves, A., Curtin, J. A., Custovic, A., Daley, D., de Jongste, J. C., Del-Rio-Navarro, B. E., Donohue, K. M., Duijts, L., Eng, C., Eriksson, J. G., Farrall, M., Fedorova, Y., Feenstra, B., Ferreira, M. A., Freidin, M. B., Gajdos, Z., Gauderman, J., Gehring, U., Geller, F., Genuneit, J., Gharib, S. A., Gilliland, F., Heckbert, S. R., Hottenga, J., Mbarek, H., Willemsen, G. & Australian Asthma Genetics Consortium (AAGC) collaborators, Jan 2018, In : Nature Genetics. 50, 1, p. 42-53 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Polygenic prediction of obsessive compulsive symptoms

Rodrigues Zilhao Nogueira, N., Abdellaoui, A., Smit, D. J. A., Cath, D. C., Hottenga, J. J. & Boomsma, D. I., 1 Feb 2018, In : Molecular Psychiatry. 23, 2, p. 168-169 2 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Polygenic risk for alcohol consumption and its association with alcohol-related phenotypes: Do stress and life satisfaction moderate these relationships?

Mies, G. W., Verweij, K. J. H., Treur, J. L., Ligthart, L., Fedko, I. O., Hottenga, J. J., Willemsen, G., Bartels, M., Boomsma, D. I. & Vink, J. M., 1 Jan 2018, In : Drug and Alcohol Dependence. 183, p. 7-12 6 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Predicting loneliness with polygenic scores of social, psychological and psychiatric traits

Abdellaoui, A., Nivard, M. G., Hottenga, J. J., Fedko, I., Verweij, K. J. H., Baselmans, B. M. L., Ehli, E. A., Davies, G. E., Bartels, M., Boomsma, D. I. & Cacioppo, J. T., Jul 2018, In : Genes, Brain and Behavior. 17, 6, p. 1-10 10 p., e12472.

Research output: Contribution to JournalArticleAcademicpeer-review

Testing familial transmission of smoking with two different research designs

Treur, J. L., Verweij, K. J. H., Abdellaoui, A., Fedko, I. O., de Zeeuw, E. L., Ehli, E. A., Davies, G. E., Hottenga, J. J., Willemsen, G., Boomsma, D. I. & Vink, J. M., 7 Jun 2018, In : Nicotine and Tobacco Research. 20, 7, p. 836-842 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

2017

2SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio

Lin, B. D., Carnero-Montoro, E., Bell, J. T., Boomsma, D. I., de Geus, E. J., Jansen, R., Kluft, C., Mangino, M., Penninx, B., Spector, T. D., Willemsen, G. & Hottenga, J-J., Nov 2017, In : Journal of human genetics. 62, 11, p. 979-988 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

A framework for the detection of de novo mutations in family-based sequencing data

Francioli, L. C., Cretu-Stancu, M., Garimella, K. V., Fromer, M., Kloosterman, W. P., Boomsma, D. I., Abdellaoui, A., Hottenga, J. J., Willemsen, G., Samocha, K. E., Neale, B. M., Daly, M. J., Banks, E., DePristo, M. A. & Bakker, P. I. W., Jan 2017, In : European Journal of Human Genetics. 25, 2, p. 227-233 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

A method to customize population-specific arrays for genome-wide association testing

Ehli, E. A., Abdellaoui, A., Fedko, I. O., Grieser, C., Nohzadeh-Malakshah, S., Willemsen, G., de Geus, E. J. C., Boomsma, D. I., Davies, G. E. & Hottenga, J. J., 1 Feb 2017, In : European Journal of Human Genetics. 25, 2, p. 267-270 4 p.

Research output: Contribution to JournalArticleAcademicpeer-review

An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype

Direk, N., Williams, S., Smith, J. A., Ripke, S., Air, T., Amare, A. T., Amin, N., Baune, B. T., Bennett, D. A., Blackwood, D. H. R., Boomsma, D., Breen, G., Buttenschøn, H. N., Byrne, E. M., Børglum, A. D., Castelao, E., Cichon, S., Clarke, T-K., Cornelis, M. C., Dannlowski, U. & 82 others, De Jager, P. L., Demirkan, A., Domenici, E., van Duijn, C. M., Dunn, E. C., Eriksson, J. G., Esko, T., Faul, J. D., Ferrucci, L., Fornage, M., de Geus, E., Gill, M., Gordon, S. D., Grabe, H-J., van Grootheest, G., Hamilton, S. P., Hartman, C. A., Heath, A. C., Hek, K., Hofman, A., Homuth, G., Horn, C., Jan Hottenga, J., Kardia, S. L. R., Kloiber, S., Koenen, K., Kutalik, Z., Ladwig, K-H., Lahti, J., Levinson, D. F., Lewis, C. M., Lewis, G., Li, Q. S., Llewellyn, D. J., Lucae, S., Lunetta, K. L., MacIntyre, D. J., Madden, P. A. F., Martin, N. G., McIntosh, A. M., Metspalu, A., Milaneschi, Y., Montgomery, G. W., Mors, O., Mosley, T. H., Murabito, J. M., Müller-Myhsok, B., Nöthen, M. M., Nyholt, D. R., O'Donovan, M. C., Penninx, B. W., Pergadia, M. L., Perlis, R., Potash, J. B., Preisig, M., Purcell, S. M., Quiroz, J. A., Räikkönen, K., Rice, J. P., Rietschel, M., Rivera, M., Schulze, T. G., Shi, J., Shyn, S. I., Sinnamon, G. C., Smit, J. H., Smoller, J. W., Snieder, H., Tanaka, T., Tansey, K. E., Teumer, A., Uher, R., Umbricht, D., Van der Auwera, S., Ware, E. B., Weir, D. R., Weissman, M. M., Willemsen, G., Yang, J., Zhao, W., Tiemeier, H. & Sullivan, P. F., 1 Aug 2017, In : Biological Psychiatry. 82, 5, p. 322-329 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study

de Vries, P. S., Sabater-Lleal, M., Chasman, D. I., Trompet, S., Ahluwalia, T. S., Teumer, A., Kleber, M. E., Chen, M-H., Wang, J. J., Attia, J. R., Marioni, R. E., Steri, M., Weng, L-C., Pool, R., Grossmann, V., Brody, J. A., Venturini, C., Tanaka, T., Rose, L. M., Oldmeadow, C. & 66 others, Mazur, J., Basu, S., Frånberg, M., Yang, Q., Ligthart, S., Hottenga, J. J., Rumley, A., Mulas, A., De Craen, A. J. M., Grotevendt, A., Taylor, K. D., Delgado, G. E., Kifley, A., Lopez, L. M., Berentzen, T. L., Mangino, M., Bandinelli, S., Morrison, A. C., Hamsten, A., Tofler, G., de Maat, M. P. M., Draisma, H. H. M., Lowe, G. D., Zoledziewska, M., Sattar, N., Lackner, K. J., Völker, U., McKnight, B., Huang, J., Holliday, E. G., McEvoy, M. A., Starr, J. M., Hysi, P. G., Hernandez, D. G., Guan, W., Rivadeneira, F., McArdle, W. L., Slagboom, P. E., Zeller, T., Psaty, B. M., Uitterlinden, A. G., de Geus, E. J. C., Stott, D. J., Binder, H., Hofman, A., Franco, O. H., Rotter, J. I., Ferrucci, L., Spector, T. D., Deary, I. J., März, W., Greinacher, A., Wild, P. S., Cucca, F., Boomsma, D. I., Watkins, H., Tang, W., Ridker, P. M., Jukema, J. W., Scott, R. J., Mitchell, P., Hansen, T., O'Donnell, C. J., Smith, N. L., Strachan, D. P. & Dehghan, A., 20 Jan 2017, In : PLoS ONE. 12, 1, p. e0167742 e0167742.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Conditional eQTL analysis reveals allelic heterogeneity of gene expression

Jansen, R., Hottenga, J-J., Nivard, M. G., Abdellaoui, A., Laport, B., de Geus, E. J., Wright, F. A., Penninx, B. W. J. H. & Boomsma, D. I., 15 Apr 2017, In : Human Molecular Genetics. 26, 8, p. 1444-1451 8 p., ddx043.

Research output: Contribution to JournalArticleAcademicpeer-review

Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution

van Iterson, M., van Zwet, E. W., Heijmans, B. T., ’t Hoen, P. A. C., van Meurs, J. B. J., Jansen, R., Franke, L., Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J., Van Greevenbroek, M. J., Stehouwer, C. D. A., van der Kallen, C. J. H., Schalkwijk, C. G., Wijmenga, C., Zhernakova, S., Tigchelaar, E. F., Eline Slagboom, P., Beekman, M. & 31 others, Deelen, J., van Heemst, D., Veldink, J. H., van den Berg, L. H., van Duijn, C. M., Hofman, B. A., Isaacs, A., Uitterlinden, A. G., Jhamai, P. M., Verbiest, M., Suchiman, H. E. D., Verkerk, M., van der Breggen, R., van Rooij, J., Lakenberg, N., Mei, H., van Galen, M., Bot, J., Zhernakova, D. V., van 't Hof, P., Deelen, P., Nooren, I., Moed, M., Vermaat, M., Luijk, R., Bonder, M. J., van Dijk, F., Arindrarto, W., Kielbasa, S. M., Swertz, M. A. & 't Hoen, P. B., 27 Jan 2017, In : Genome Biology. 18, 1, 19.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Disease variants alter transcription factor levels and methylation of their binding sites

Bonder, M. J., Luijk, R., Zhernakova, D. V., Moed, M., Deelen, P., Vermaat, M., van Iterson, M., van Dijk, F., van Galen, M., Bot, J., Slieker, R. C., Jhamai, P. M., Verbiest, M., Suchiman, H. E. D., Verkerk, M., van der Breggen, R., van Rooij, J., Lakenberg, N., Arindrarto, W., Kielbasa, S. M. & 31 others, Jonkers, I., van 't Hof, P., Nooren, I., Beekman, M., Deelen, J., van Heemst, D., Zhernakova, A., Tigchelaar, E. F., Swertz, M. A., Hofman, A., Uitterlinden, A. G., Pool, R., van Dongen, J., Hottenga, J. J., Stehouwer, C. D. A., van der Kallen, C. J. H., Schalkwijk, C. G., van den Berg, L. H., van Zwet, E. W., Mei, H., Li, Y., Lemire, M., Hudson, T. J., Slagboom, P. E., Wijmenga, C., Veldink, J. H., Van Greevenbroek, M. J., van Duijn, C. M., Boomsma, D. I., Isaacs, A. & BIOS Consortium, Jan 2017, In : Nature Genetics. 49, 1, p. 131-138 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation

Richard, M. A., Huan, T., Ligthart, S., Gondalia, R., Jhun, M. A., Brody, J. A., Irvin, M. R., Marioni, R., Shen, J., Tsai, P-C., Montasser, M. E., Jia, Y., Syme, C., Salfati, E. L., Boerwinkle, E., Guan, W., Mosley, T. H., Bressler, J., Morrison, A. C., Liu, C. & 31 others, Mendelson, M. M., Uitterlinden, A. G., van Meurs, J. B., Franco, O. H., Zhang, G., Li, Y., Stewart, J. D., Bis, J. C., Psaty, B. M., Chen, Y-D. I., Kardia, S. L. R., Zhao, W., Turner, S. T., Absher, D., Aslibekyan, S., Starr, J. M., McRae, A. F., Hou, L., Just, A. C., Schwartz, J. D., Vokonas, P. S., Menni, C., Spector, T. D., Shuldiner, A., Damcott, C. M., Rotter, J. I., BIOS Consortium, Boomsma, D. I., Pool, R., van Dongen, J. & Hottenga, J. J., 7 Dec 2017, In : American Journal of Human Genetics. 101, 6, p. 888-902 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

Hinney, A., Kesselmeier, M., Jall, S., Volckmar, A-L., Föcker, M., Antel, J., Heid, I. M., Winkler, T. W., Grant, S. F. A., Guo, Y., Bergen, A. W., Kaye, W., Berrettini, W., Hakonarson, H., Herpertz-Dahlmann, B., de Zwaan, M., Herzog, W., Ehrlich, S., Zipfel, S., Egberts, K. M. & 19 others, Adan, R., Brandys, M., van Elburg, A., Boraska Perica, V., Franklin, C. S., Tschöp, M. H., Zeggini, E., Bulik, C. M., Collier, D., Scherag, A., Müller, T. D., Hebebrand, J., GCAN, Hottenga, J. J., Willemsen, G., Boomsma, D. I., van Beijsterveldt, C. E. M., Middeldorp, C. M. & de Geus, E., Feb 2017, In : Molecular Psychiatry. 22, 2, p. 192-201 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic effects influencing risk for major depressive disorder in China and Europe

Bigdeli, T. B., Ripke, S., Peterson, R. E., Trzaskowski, M., Bacanu, S. A., Abdellaoui, A., Andlauer, T. F. M., Beekman, A. T. F., Berger, K., Blackwood, D. H. R., Boomsma, D. I., Breen, G., Buttenschøn, H. N., Byrne, E. M., Cichon, S., Clarke, T. K., Couvy-Duchesne, B., Craddock, N., de Geus, E. J. C., Degenhardt, F. & 77 others, Dunn, E. C., Edwards, C. A., Fanous, A. H., Forstner, A. J., Frank, J., Gill, M., Gordon, S. D. S., Grabe, H. J., Hamilton, S. P., Hardiman, O., Hayward, C., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Hottenga, J-J., Ising, M., Jansen, R., Kloiber, S., Knowles, J. A., Lang, M., Li, Q. S., Lucae, S., MacIntyre, D. J., Madden, P. A. F., Martin, N. G., McGrath, P. J., McGuffin, P., McIntosh, A. M., Medland, S. E., Mehta, D., Middeldorp, C. M., Milaneschi, Y., Montgomery, G. W., Mors, O., Müller-Myhsok, B., Nauck, M., Nyholt, D. R., Nöthen, M. M., Owen, M. J., Penninx, B. W. J. H., Pergadia, M. L., Perlis, R. H., Peyrot, W. J., Porteous, D. J., Potash, J. B., Rice, J. P., Rietschel, M., Riley, B. P., Rivera, M., Schoevers, R., Schulze, T. G., Shi, J., Shyn, S. I., Smit, J. H., Smoller, J. W., Streit, F., Strohmaier, J., Teumer, A., Treutlein, J., van der Auwera, S. V., Grootheest, G., van Hemert, A. M., Völzke, H., Webb, B. T., Weissman, M. M., Wellmann, J., Willemsen, G., Witt, S. H., Levinson, D. F., Lewis, C. M., Wray, N. R., Flint, J., Sullivan, P. F. & Kendler, K. S., 28 Mar 2017, In : Translational Psychiatry. 7, 3, p. e1074 e1074.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genetic loci associated with heart rate variability and their effects on cardiac disease risk

Nolte, I. M., Munoz, M. L., Tragante, V., Amare, A. T., Jansen, R., Vaez, A., von der Heyde, B., Avery, C. L., Bis, J. C., Dierckx, B., van Dongen, J., Gogarten, S. M., Goyette, P., Hernesniemi, J., Huikari, V., Hwang, S-J., Jaju, D., Kerr, K. F., Kluttig, A., Krijthe, B. P. & 144 others, Kumar, J., van der Laan, S. W., Lyytikäinen, L-P., Maihofer, A. X., Minassian, A., van der Most, P. J., Müller-Nurasyid, M., Nivard, M., Salvi, E., Stewart, J. D., Thayer, J. F., Verweij, N., Wong, A., Zabaneh, D., Zafarmand, M. H., Abdellaoui, A., Albarwani, S., Albert, C., Alonso, A., Ashar, F., Auvinen, J., Axelsson, T., Baker, D. G., de Bakker, P. I. W., Barcella, M., Bayoumi, R., Bieringa, R. J., Boomsma, D., Boucher, G., Britton, A. R., Christophersen, I., Dietrich, A., Ehret, G. B., Ellinor, P. T., Eskola, M., Felix, J. F., Floras, J. S., Franco, O. H., Friberg, P., Gademan, M. G. J., Geyer, M. A., Giedraitis, V., Hartman, C. A., Hemerich, D., Hofman, A., Hottenga, J-J., Huikuri, H., Hutri-Kähönen, N., Jouven, X., Junttila, J., Juonala, M., Kiviniemi, A. M., Kors, J. A., Kumari, M., Kuznetsova, T., Laurie, C. C., Lefrandt, J. D., Li, Y., Li, Y., Liao, D., Limacher, M. C., Lin, H. J., Lindgren, C. M., Lubitz, S. A., Mahajan, A., McKnight, B., Zu Schwabedissen, H. M., Milaneschi, Y., Mononen, N., Morris, A. P., Nalls, M. A., Navis, G., Neijts, M., Nikus, K., North, K. E., O'Connor, D. T., Ormel, J., Perz, S., Peters, A., Psaty, B. M., Raitakari, O. T., Risbrough, V. B., Sinner, M. F., Siscovick, D., Smit, J. H., Smith, N. L., Soliman, E. Z., Sotoodehnia, N., Staessen, J. A., Stein, P. K., Stilp, A. M., Stolarz-Skrzypek, K., Strauch, K., Sundström, J., Swenne, C. A., Syvänen, A-C., Tardif, J-C., Taylor, K. D., Teumer, A., Thornton, T. A., Tinker, L. E., Uitterlinden, A. G., van Setten, J., Voss, A., Waldenberger, M., Wilhelmsen, K. C., Willemsen, G., Wong, Q., Zhang, Z-M., Zonderman, A. B., Cusi, D., Evans, M. K., Greiser, H. K., van der Harst, P., Hassan, M., Ingelsson, E., Järvelin, M-R., Kääb, S., Kähönen, M., Kivimaki, M., Kooperberg, C., Kuh, D., Lehtimäki, T., Lind, L., Nievergelt, C. M., O'Donnell, C. J., Oldehinkel, A. J., Penninx, B., Reiner, A. P., Riese, H., Van Roon, A. M., Rioux, J. D., Rotter, J. I., Sofer, T., Stricker, B. H., Tiemeier, H., Vrijkotte, T. G. M., Asselbergs, F. W., Brundel, B. J. J. M., Heckbert, S. R., Whitsel, E. A., den Hoed, M., Snieder, H. & de Geus, E. J. C., 14 Jun 2017, In : Nature Communications. 8, p. 15805 15805.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genetic loci associated with heart rate variability and their effects on cardiac disease risk (vol 8, pg 15805, 2017)

Nolte, I. M., Munoz, M. L., Tragante, V., Amare, A. T., Jansen, R., Vaez, A., von der Heyde, B., Avery, C. L., Bis, J. C., Dierckx, B., van Dongen, J., Gogarten, S. M., Goyette, P., Hernesniemi, J., Huikari, V., Hwang, S-J., Jaju, D., Kerr, K. F., Kluttig, A., Krijthe, B. P. & 144 others, Kumar, J., van der Laan, S. W., Lyytikainen, L-P., Maihofer, A. X., Minassian, A., van der Most, P. J., Mueller-Nurasyid, M., Nivard, M., Salvi, E., Stewart, J. D., Thayer, J. F., Verweij, N., Wong, A., Zabaneh, D., Zafarmand, M. H., Abdellaoui, A., Albarwani, S., Albert, C., Alonso, A., Ashar, F., Auvinen, J., Axelsson, T., Baker, D. G., de Bakker, P. I. W., Barcella, M., Bayoumi, R., Bieringa, R. J., Boomsma, D., Boucher, G., Britton, A. R., Christophersen, I., Dietrich, A., Ehret, G. B., Ellinor, P. T., Eskola, M., Felix, J. F., Floras, J. S., Franco, O. H., Friberg, P., Gademan, M. G. J., Geyer, M. A., Giedraitis, V., Hartman, C. A., Hemerich, D., Hofman, A., Hottenga, J-J., Huikuri, H., Hutri-Kahonen, N., Jouven, X., Junttila, J., Juonala, M., Kiviniemi, A. M., Kors, J. A., Kumari, M., Kuznetsova, T., Laurie, C. C., Lefrandt, J. D., Li, Y., Li, Y., Liao, D., Limacher, M. C., Lin, H. J., Lindgren, C. M., Lubitz, S. A., Mahajan, A., McKnight, B., zu Schwabedissen, H. M., Milaneschi, Y., Mononen, N., Morris, A. P., Nalls, M. A., Navis, G., Neijts, M., Nikus, K., North, K. E., O'Connor, D. T., Ormel, J., Perz, S., Peters, A., Psaty, B. M., Raitakari, O. T., Risbrough, V. B., Sinner, M. F., Siscovick, D., Smit, J. H., Smith, N. L., Soliman, E. Z., Sotoodehnia, N., Staessen, J. A., Stein, P. K., Stilp, A. M., Stolarz-Skrzypek, K., Strauch, K., Sundstrom, J., Swenne, C. A., Syvanen, A-C., Tardif, J-C., Taylor, K. D., Teumer, A., Thornton, T. A., Tinker, L. E., Uitterlinden, A. G., van Setten, J., Voss, A., Waldenberger, M., Wilhelmsen, K. C., Willemsen, G., Wong, Q., Zhang, Z-M., Zonderman, A. B., Cusi, D., Evans, M. K., Greiser, H. K., van der Harst, P., Hassan, M., Ingelsson, E., Jarvelin, M-R., Kaab, S., Kahonen, M., Kivimaki, M., Kooperberg, C., Kuh, D., Lehtimaki, T., Lind, L., Nievergelt, C. M., O'Donnell, C. J., Oldehinkel, A. J., Penninx, B., Reiner, A. P., Riese, H., van Roon, A. M., Rioux, J. D., Rotter, J. I., Sofer, T., Stricker, B. H., Tiemeier, H., Vrijkotte, T. G. M., Asselbergs, F. W., Brundel, B. J. J. M., Heckbert, S. R., Whitsel, E. A., den Hoed, M., Snieder, H. & de Geus, E. J. C., 2 Aug 2017, In : Nature Communications. 8

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

Warren, H. R., Evangelou, E., Cabrera, C. P., Gao, H., Ren, M., Mifsud, B., Ntalla, I., Surendran, P., Liu, C., Cook, J. P., Kraja, A. T., Drenos, F., Loh, M., Verweij, N., Marten, J., Karaman, I., Lepe, M. P. S., O'Reilly, P. F., Knight, J., Snieder, H. & 31 others, Kato, N., He, J., Tai, E. S., Said, M. A., Porteous, D., Alver, M., Poulter, N., Farrall, M., Gansevoort, R. T., Padmanabhan, S., Mägi, R., Stanton, A., Connell, J., Bakker, S. J. L., Metspalu, A., Shields, D. C., Thom, S., Brown, M., Sever, P., Esko, T., Hayward, C., van der Harst, P., Saleheen, D., Chowdhury, R., Chambers, J. C., Chasman, D. I., International Consortium of Blood Pressure (ICBP) 1000G Analyses, Hottenga, J. J., de Geus, E., Willemsen, G. & Boomsma, D. I., Mar 2017, In : Nature Genetics. 49, 3, p. 403-415 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

Power, R. A., Tansey, K. E., Buttenschøn, H. N., Cohen-Woods, S., Bigdeli, T., Hall, L. S., Kutalik, Z., Lee, S. H., Ripke, S., Steinberg, S., Teumer, A., Viktorin, A., Wray, N. R., Arolt, V., Baune, B. T., Boomsma, D. I., Børglum, A. D., Byrne, E. M., Castelao, E., Craddock, N. & 31 others, Craig, I. W., Dannlowski, U., Deary, I. J., Degenhardt, F., Forstner, A. J., Gordon, S. D., Grabe, H. J., Grove, J., Hamilton, S. P., Hayward, C., Heath, A. C., Hocking, L. J., Homuth, G., Hottenga, J. J., Kloiber, S., Krogh, J., Landén, M., Lang, M., Levinson, D. F., Lichtenstein, P., Lucae, S., MacIntyre, D. J., Madden, P. A. F., Magnusson, P. K. E., Martin, N. G., McIntosh, A. M., Middeldorp, C. M., Milaneschi, Y., Penninx, B. W. J. H., Smit, J. H. & CONVERGE Consortium, CARDIoGRAM Consortium, GERAD1 Consortium, 15 Feb 2017, In : Biological Psychiatry. 81, 4, p. 325-335 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

Witt, S. H., Streit, F., Jungkunz, M., Frank, J., Awasthi, S., Reinbold, C. S., Treutlein, J., Degenhardt, F., Forstner, A. J., Heilmann-Heimbach, S., Dietl, L., Schwarze, C. E., Schendel, D. J., Strohmaier, J., Abdellaoui, A., Adolfsson, R., Air, T. M., Akil, H., Lopezz de Alda, M., Alliey-Rodriguez, N. & 31 others, Andreassen, O. A., Babadjanova, G., Bass, N. J., Bauer, M., Baune, B. T., Bellivier, F., Bergen, S. E., Bethell, A., Biernacka, J. M., Blackwood, D. H. R., Boks, M. P., Boomsma, D. I., Børglum, A. D., Borrmann-Hassenbach, M., Brennan, P., Budde, M., Buttenschøn, H. N., Byrne, E. M., Cervantes, P., Clarke, T. K., Craddock, N., Cruceanu, C., Curtis, D., de Geus, E. J. C., Fischer, S. B., Hottenga, J-J., Middeldorp, C. M., Milaneschi, Y., Penninx, B. W. J. H., Willemsen, G. & Bipolar Disorders Working Group of the Psychiatric Genomics Consortium, 20 Jun 2017, In : Translational Psychiatry. 7, 6, p. e1155

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., Shen, X., Gandin, I., McDaid, A. F., Hansen, T. F., Gordon, S. D., Giulianini, F., Boutin, T. S., Abdellaoui, A., Zhao, W., Medina-Gomez, C. & 93 others, Bartz, T. M., Trompet, S., Lange, L. A., Raffield, L., van der Spek, A., Galesloot, T. E., Proitsi, P., Yanek, L. R., Bielak, L. F., Payton, A., Murgia, F., Concas, M. P., Biino, G., Tajuddin, S. M., Seppälä, I., Amin, N., Boerwinkle, E., Børglum, A. D., Campbell, A., Demerath, E. W., Demuth, I., Faul, J. D., Ford, I., Gialluisi, A., Gögele, M., Graff, M., Hingorani, A., Hottenga, J-J., Hougaard, D. M., Hurme, M. A., Ikram, M. A., Jylhä, M., Kuh, D., Ligthart, L., Lill, C. M., Lindenberger, U., Lumley, T., Mägi, R., Marques-Vidal, P., Medland, S. E., Milani, L., Nagy, R., Ollier, W. E. R., Peyser, P. A., Pramstaller, P. P., Ridker, P. M., Rivadeneira, F., Ruggiero, D., Saba, Y., Schmidt, R., Schmidt, H., Slagboom, P. E., Smith, B. H., Smith, J. A., Sotoodehnia, N., Steinhagen-Thiessen, E., van Rooij, F. J. A., Verbeek, A. L., Vermeulen, S. H., Vollenweider, P., Wang, Y., Werge, T., Whitfield, J. B., Zonderman, A. B., Lehtimäki, T., Evans, M. K., Pirastu, M., Fuchsberger, C., Bertram, L., Pendleton, N., Kardia, S. L. R., Ciullo, M., Becker, D. M., Wong, A., Psaty, B. M., van Duijn, C. M., Wilson, J. G., Jukema, J. W., Kiemeney, L., Uitterlinden, A. G., Franceschini, N., North, K. E., Weir, D. R., Metspalu, A., Boomsma, D. I., Hayward, C., Chasman, D., Martin, N. G., Sattar, N., Campbell, H., Esko, T., Kutalik, Z. & Wilson, J. F., 13 Oct 2017, In : Nature Communications. 8, 1, p. 910 910.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

Justice, A. E., Winkler, T. W., Feitosa, M. F., Graff, M., Fisher, V. A., Young, K. L., Barata, L., Deng, X., Czajkowski, J., Hadley, D., Ngwa, J. S., Ahluwalia, T. S., Chu, A. Y., Heard-Costa, N. L., Lim, E., Perez, J., Eicher, J. D., Kutalik, Z., Xue, L., Mahajan, A. & 297 others, Renström, F., Wu, J., Qi, Q., Ahmad, S., Alfred, T., Amin, N., Bielak, L. F., Bonnefond, A., Bragg-Gresham, J. L., Cadby, G., Chittani, M., Coggeshall, S., Corre, T., Direk, N., Eriksson, J., Fischer, K., Gorski, M., Neergaard Harder, M., Horikoshi, M., Huang, T., Huffman, J. E., Jackson, A. U., Justesen, J. M., Kanoni, S., Kinnunen, L., Kleber, M. E., Komulainen, P., Kumari, M., Lim, U., Luan, J., Lyytikäinen, L-P., Mangino, M., Manichaikul, A., Marten, J., Middelberg, R. P. S., Müller-Nurasyid, M., Navarro, P., Pérusse, L., Pervjakova, N., Sarti, C., Smith, A. V., Smith, J. A., Stančáková, A., Strawbridge, R. J., Stringham, H. M., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., van der Laan, S. W., van der Most, P. J., van Vliet-Ostaptchouk, J. V., Vedantam, S. L., Verweij, N., Vink, J. M., Vitart, V., Wu, Y., Yengo, L., Zhang, W., Hua Zhao, J., Zimmermann, M. E., Zubair, N., Abecasis, G. R., Adair, L. S., Afaq, S., Afzal, U., Bakker, S. J. L., Bartz, T. M., Beilby, J., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E., Braga, D., Buckley, B. M., Buyske, S., Campbell, H., Chambers, J. C., Collins, F. S., Curran, J. E., de Borst, G. J., De Craen, A. J. M., de Geus, E. J. C., Dedoussis, G., Delgado, G. E., den Ruijter, H. M., Eiriksdottir, G., Eriksson, A. L., Esko, T., Faul, J. D., Ford, I., Forrester, T., Gertow, K., Gigante, B., Glorioso, N., Gong, J., Grallert, H., Grammer, T. B., Grarup, N., Haitjema, S., Hallmans, G., Hamsten, A., Hansen, T., Harris, T. B., Hartman, C. A., Hassinen, M., Hastie, N. D., Heath, A. C., Hernandez, D. G., Hindorff, L., Hocking, L. J., Hollensted, M., Holmen, O. L., Homuth, G., Huang, J., Hung, J., Hutri-Kähönen, N., Ingelsson, E., James, A. L., Jansson, J-O., Jarvelin, M-R., Jhun, M. A., Jørgensen, M. E., Juonala, M., Kähönen, M., Karlsson, M., Koistinen, H. A., Kolcic, I., Kolovou, G., Kooperberg, C., Krämer, B. K., Kuusisto, J., Kvaløy, K., Lakka, T. A., Langenberg, C., Launer, L. J., Leander, K., Lee, N. R., Lind, L., Lindgren, C. M., Linneberg, A., Lobbens, S., Loh, M., Lorentzon, M., Luben, R., Lubke, G., Ludolph-Donislawski, A., Lupoli, S., Madden, P. A. F., Männikkö, R., Marques-Vidal, P. M., Martin, N. G., McKenzie, C. A., McKnight, B., Mellström, D., Menni, C., Montgomery, G. W., Musk, A. B., Narisu, N., Nauck, M., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Peyser, P. A., Pisinger, C., Porteous, D. J., Raitakari, O. T., Rankinen, T., Rao, D. C., Rasmussen-Torvik, L. J., Rawal, R., Rice, T., Ridker, P. M., Rose, L. M., Bien, S. A., Rudan, I., Sanna, S., Sarzynski, M. A., Sattar, N., Savonen, K., Schlessinger, D., Scholtens, S., Schurmann, C., Scott, R. A., Sennblad, B., Siemelink, M. A., Silbernagel, G., Slagboom, P. E., Snieder, H., Staessen, J. A., Stott, D. J., Swertz, M. A., Swift, A. J., Taylor, K. D., Tayo, B. O., Thorand, B., Thuillier, D., Tuomilehto, J., Uitterlinden, A. G., Vandenput, L., Vohl, M-C., Völzke, H., Vonk, J. M., Waeber, G., Waldenberger, M., Westendorp, R. G. J., Wild, S., Willemsen, G., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zhao, W., Zillikens, M. C., Baldassarre, D., Balkau, B., Bandinelli, S., Böger, C. A., Boomsma, D. I., Bouchard, C., Bruinenberg, M., Chasman, D. I., Chen, Y-D., Chines, P. S., Cooper, R. S., Cucca, F., Cusi, D., Faire, U. D., Ferrucci, L., Franks, P. W., Froguel, P., Gordon-Larsen, P., Grabe, H-J., Gudnason, V., Haiman, C. A., Hayward, C., Hveem, K., Johnson, A. D., Wouter Jukema, J., Kardia, S. L. R., Kivimaki, M., Kooner, J. S., Kuh, D., Laakso, M., Lehtimäki, T., Marchand, L. L., März, W., McCarthy, M. I., Metspalu, A., Morris, A. P., Ohlsson, C., Palmer, L. J., Pasterkamp, G., Pedersen, O., Peters, A., Peters, U., Polasek, O., Psaty, B. M., Qi, L., Rauramaa, R., Smith, B. H., Sørensen, T. I. A., Strauch, K., Tiemeier, H., Tremoli, E., van der Harst, P., Vestergaard, H., Vollenweider, P., Wareham, N. J., Weir, D. R., Whitfield, J. B., Wilson, J. F., Tyrrell, J., Frayling, T. M., Barroso, I., Boehnke, M., Deloukas, P., Fox, C. S., Hirschhorn, J. N., Hunter, D. J., Spector, T. D., Strachan, D. P., van Duijn, C. M., Heid, I. M., Mohlke, K. L., Marchini, J., Loos, R. J. F., Kilpeläinen, T. O., Liu, C-T., Borecki, I. B., North, K. E., Cupples, L. A. & Hottenga, J. J., 26 Apr 2017, In : Nature Communications. 8, p. 14977 14977.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D. & 31 others, Hayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P. M., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, J. M., Kleber, M. E., Hollensted, M., Lohman, K., Huppertz, C., Willemsen, G., Hottenga, J. J., Milaneschi, Y., De Moor, M. H. M., Penninx, B. W. J. H., de Geus, E. J. C., Boomsma, D. I. & CHARGE Consortium, Apr 2017, In : PLoS Genetics. 13, 4, p. e1006528 e1006528.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-wide Regional Heritability Mapping Identifies a Locus Within the TOX2 Gene Associated With Major Depressive Disorder

Zeng, Y., Navarro, P., Shirali, M., Howard, D. M., Adams, M. J., Hall, L. S., Clarke, T-K., Thomson, P. A., Smith, B. H., Murray, A., Padmanabhan, S., Hayward, C., Boutin, T., MacIntyre, D. J., Lewis, C. M., Wray, N. R., Mehta, D., Penninx, B. W. J. H., Milaneschi, Y., Baune, B. T. & 20 others, Air, T., Hottenga, J-J., Mbarek, H., Castelao, E., Pistis, G., Schulze, T. G., Streit, F., Forstner, A. J., Byrne, E. M., Martin, N. G., Breen, G., Müller-Myhsok, B., Lucae, S., Kloiber, S., Domenici, E., Deary, I. J., Porteous, D. J., Haley, C. S., McIntosh, A. M. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Sep 2017, In : Biological Psychiatry. 82, 5, p. 312-321 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Genome-Wide Significance for PCLO as a Gene for Major Depressive Disorder

Mbarek, H., Milaneschi, Y., Hottenga, J-J., Ligthart, L., de Geus, E. J. C., Ehli, E. A., Willemsen, G., Davies, G. E., Smit, J. H., Boomsma, D. I. & Penninx, B. W. J. H., 1 Aug 2017, In : Twin Research and Human Genetics. 20, 4, p. 267-270 4 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

Day, F. R., Thompson, D. J., Helgason, H., Chasman, D. I., Finucane, H., Sulem, P., Ruth, K. S., Whalen, S., Sarkar, A. K., Albrecht, E., Altmaier, E., Amini, M., Barbieri, C. M., Boutin, T., Campbell, A., Demerath, E., Giri, A., He, C., Hottenga, J. J., Karlsson, R. & 31 others, Kolcic, I., Loh, P-R., Lunetta, K. L., Mangino, M., Marco, B., McMahon, G., Medland, S. E., Nolte, I. M., Noordam, R., Nutile, T., Paternoster, L., Perjakova, N., Porcu, E., Rose, L. M., Schraut, K. E., Segrè, A. V., Smith, A. V., Stolk, L., Teumer, A., Andrulis, I. L., Bandinelli, S., Beckmann, M. W., Benitez, J., Bergmann, S., Bochud, M., de Geus, E. J. C. N., Mbarek, H., Willemsen, G., Boomsma, D. I., Visser, J. A. & LifeLines Cohort Study, 1 Jun 2017, In : Nature Genetics. 49, 6, p. 834-841 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes

Rietschel, L., Streit, F., Zhu, G., McAloney, K., Frank, J., Couvy-Duchesne, B., Witt, S. H., Binz, T. M., McGrath, J., Hickie, I. B., Hansell, N. K., Wright, M. J., Gillespie, N. A., Forstner, A. J., Schulze, T. G., Wüst, S., Nöthen, M. M., Baumgartner, M. R., Walker, B. R., Crawford, A. A. & 12 others, Colodro-Conde, L., Medland, S. E., Martin, N. G., Rietschel, M., CORtisolNETwork (CORNET) Consortium, Abdellaoui, A., de Geus, E., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Willemsen, G. & Boomsma, D. I., 10 Nov 2017, In : Scientific Reports. 7, 1, p. 15351 15351.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Heritability and GWAS Studies for Monocyte-Lymphocyte Ratio

Lin, B. D., Willemsen, G., Fedko, I. O., Jansen, R., Penninx, B. W. J. H., de Geus, E., Kluft, C., Hottenga, J. J. & Boomsma, D. I., Mar 2017, In : Twin Research and Human Genetics. 20, 2, p. 97-107 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access

Identification of context-dependent expression quantitative trait loci in whole blood

Zhernakova, D. V., Deelen, P., Vermaat, M., van Iterson, M., van Galen, M., Arindrarto, W., van 't Hof, P., Mei, H., van Dijk, F., Westra, H-J., Bonder, M. J., van Rooij, J., Verkerk, M., Jhamai, P. M., Moed, M., Kielbasa, S. M., Bot, J., Nooren, I., Pool, R., van Dongen, J. & 27 others, Hottenga, J. J., Stehouwer, C. D. A., van der Kallen, C. J. H., Schalkwijk, C. G., Zhernakova, A., Li, Y., Tigchelaar, E. F., de Klein, N., Beekman, M., Deelen, J., van Heemst, D., van den Berg, L. H., Hofman, A., Uitterlinden, A. G., Van Greevenbroek, M. J., Veldink, J. H., Boomsma, D. I., van Duijn, C. M., Wijmenga, C., Slagboom, P. E., Swertz, M. A., Isaacs, A., van Meurs, J. B. J., Jansen, R., Heijmans, B. T., ’t Hoen, P. A. C. & Franke, L., Jan 2017, In : Nature Genetics. 49, 1, p. 139-145 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review