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  • 7 Similar Profiles
Saccharomyces cerevisiae Medicine & Life Sciences
Cell Wall Medicine & Life Sciences
Ligands Chemical Compounds
CXCR3 Receptors Medicine & Life Sciences
Chemokine Receptors Chemical Compounds
CXCR4 Receptors Medicine & Life Sciences
Phenotype Medicine & Life Sciences
Amino Acid Transport Systems Medicine & Life Sciences

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Research Output 1997 2019

Structure-based exploration and pharmacological evaluation of N-substituted piperidin-4-yl-methanamine CXCR4 chemokine receptor antagonists

Adlere, I., Sun, S., Zarca, A., Roumen, L., Gozelle, M., Viciano Perpiñá, C., Caspar, B., Arimont, M., Bebelman, J. P., Briddon, S. J., Hoffmann, C., Hill, S. J., Smit, M. J., Vischer, H. F., Wijtmans, M., de Graaf, C., de Esch, I. J. P. & Leurs, R., 15 Jan 2019, In : European Journal of Medicinal Chemistry. 162, p. 631-649 19 p.

Research output: Contribution to JournalArticleAcademicpeer-review

CXCR4 Receptors
Quantitative Structure-Activity Relationship
Chemokine Receptors
Screening
Pharmacology

Photoswitching the Efficacy of a Small-Molecule Ligand for a Peptidergic GPCR: from Antagonism to Agonism

Gómez-Santacana, X., de Munnik, S. M., Vijayachandran, P., Da Costa Pereira, D., Bebelman, J. P. M., de Esch, I. J. P., Vischer, H. F., Wijtmans, M. & Leurs, R., 3 Sep 2018, In : Angewandte Chemie - International Edition. 57, 36, p. 11608-11612 5 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Ligands
Molecules
Chemical activation
Electrophysiology
Proteins

Surface plasmon resonance biosensor assay for the analysis of small-molecule inhibitor binding to human and parasitic phosphodiesterases.

Siderius, M. H., Shanmugham, A., England, P., van der Meer, T. K., Bebelman, J. P., Blaazer, A. R., de Esch, I. J. P. & Leurs, R., 2016, In : Analytical Biochemistry. 503, p. 41-49

Research output: Contribution to JournalArticleAcademicpeer-review

Surface Plasmon Resonance
Phosphoric Diester Hydrolases
Surface plasmon resonance
Biosensing Techniques
Biosensors

The CXCR3-CXCL11 signaling axis mediates macrophage recruitment and dissemination of mycobacterial infection.

Torraca, V., Cui, C., Boland, R., Bebelman, J. P., van der Sar, A. M., Smit, M. J., Siderius, M. H., Spaink, H. P. & Meijer, A. H., 2016, In : Disease Models and Mechanisms. 8, 3, p. 253-269

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
CXCR3 Receptors
Macrophages
Zebrafish
Infection
Tuberculosis

Thermosensitivity of the Saccharomyces cerevisiae gpp1gpp2 double deletion strain can be reduced by overexpression of genes involved in cell wall maintenance

Wojda, I., Bebelman, J. P., Jakubowicz, T. & Siderius, M. H., 2007, In : Archives of Microbiology. 188, 2, p. 175-84

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
File
Yeast
Cell Wall
Saccharomyces cerevisiae
Genes
Cells

Activities 2001 2001

  • 3 Lecture / Presentation

hyper-osmotic stress response and regulation of cell wall integrity

R. Alonso Monge (Speaker), E Real (Speaker), I Wojda (Speaker), J.P. Bebelman (Speaker), W.H. Mager (Speaker), M.H. Siderius (Speaker)
25 Aug 2001

Activity: Lecture / PresentationAcademic

hyper-osmotic stress response and regulation of cell wall integrity in Saccharomyces cerevisiae share common functional aspects

R. Alonso Monge (Speaker), E Real (Speaker), I Wojda (Speaker), J.P. Bebelman (Speaker), W.H. Mager (Speaker), M.H. Siderius (Speaker)
25 Aug 2001

Activity: Lecture / PresentationAcademic

hyper-osmotic stress response and regulation of cell wall integrity in Saccharomyces cerevisiae share common functional aspects.

R. Alonso Monge (Speaker), E Real (Speaker), I Wojda (Speaker), J.P. Bebelman (Speaker), W.H. Mager (Speaker), M.H. Siderius (Speaker)
4 May 2001

Activity: Lecture / PresentationAcademic