Research output per year
Research output per year
Personal profile
Personal information
I am an enthusiastic and skilled systems biologist who can efficiently collaborate and communicate with researchers in various discipline”
In my research, I combine wetlab experiments with computational modelling to advance quantitative understanding of biological processes in healthy and disease cells. I have mainly applied this in metabolism and the gene expression cascade
Specialties: Metabolism, 'pathogens' in the context of the host environment (e.g. trypanosomes in the bloodstream, cancer cells amidst healthy cells), mathematical modeling, blood cells, tumerogenesis, mouse models
Research
Current projects
- ErasysApp IMOMESIC: This project aims to obtain systems understanding on how the integration of metabolism and signalling is altered in liver cancer cells compared to the healthy liver.
- Together with bachelor and master students, I have several computational and experimental projects on energy metabolism in parasites
Ancillary activities
- COST ACTION CM1307 | Amsterdam | Memberof the Management Committee for the Netherlands | 2015-03-02 - present
- VVE Ravelijn | Utrecht | Bestuurder | 2015-04-01 - present
Ancillary activities are updated daily
Keywords
- QR Microbiology
- Trypanosoma brucei
Fingerprint
Dive into the research topics where Jurgen Haanstra is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 2 Similar Profiles
Network
Recent external collaboration on country level. Dive into details by clicking on the dots or
Research output
-
Quantitative analysis of amino acid metabolism in liver cancer links glutamate excretion to nucleotide synthesis
Nilsson, A., Haanstra, J. R., Engqvist, M., Gerding, A., Bakker, B. M., Klingmüller, U., Teusink, B. & Nielsen, J., 12 May 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 19, p. 10294-10304 11 p.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Targeting pathogen metabolism without collateral damage to the host.
Haanstra, J. R., Gerding, A., Dolga, A. M., Sorgdrager, F. J., Buist-Homan, M., du Toit, F., Faber, K. N., Holzhutter, H. G., Szoor, B., Matthews, K. R., Snoep, J. L., Westerhoff, H. V. & Bakker, B. M., 2017, In: Scientific Reports. 7, 40406.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Biogenesis, maintenance and dynamics of glycosomes in trypanosomatid parasites.
Haanstra, J. R., González-Marcano, E. B., Gualdrón-López, M. & Michels, P. A., 2016, In: Biochimica et Biophysica Acta. Molecular Cell Research. 1863, 5, p. 1038-1048Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Transcriptome-wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co-transcriptional degradation in determining mRNA levels.
Fadda, A., Ryten, M., Droll, D., Rojas, F., Farber, V., Haanstra, J. R., Merce, C., Bakker, B. M., Matthews, K. & Clayton, C., 2014, In: Molecular Microbiology. 94, p. 307-326 12764.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access -
Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux
Bosdriesz, E., Wortel, M. T., Haanstra, J. R., Wagner, M. J., De La Torre Cortés, P. & Teusink, B., 3 Apr 2018, In: Scientific Reports. 8, 1, p. 1-9 9 p., 5576.Research output: Contribution to Journal › Article › Academic › peer-review
Open Access
Datasets
-
Additional file 6: of Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal protein expression
Antwi, E. (Contributor), Haanstra, J. (Contributor), Ramasamy, G. (Contributor), Jensen, B. (Contributor), Droll, D. (Contributor), Rojas, F. (Contributor), Minia, I. (Contributor), Terrao, M. (Contributor), MercĂŠ, C. (Contributor), Matthews, K. (Contributor), Myler, P. (Contributor), Parsons, M. (Contributor) & Clayton, C. (Contributor), Unknown Publisher, 26 Apr 2016
DOI: 10.6084/m9.figshare.c.3636047_d1.v1, https://springernature.figshare.com/articles/dataset/Additional_file_6_of_Integrative_analysis_of_the_Trypanosoma_brucei_gene_expression_cascade_predicts_differential_regulation_of_mRNA_processing_and_unusual_control_of_ribosomal_protein_expression/4440302/1
Dataset
-
Additional file 17: Table S3. of Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal protein expression
Antwi, E. (Contributor), Haanstra, J. (Contributor), Ramasamy, G. (Contributor), Jensen, B. (Contributor), Droll, D. (Contributor), Rojas, F. (Contributor), Minia, I. (Contributor), Terrao, M. (Contributor), MercĂŠ, C. (Contributor), Matthews, K. (Contributor), Myler, P. (Contributor), Parsons, M. (Contributor) & Clayton, C. (Contributor), Unknown Publisher, 26 Apr 2016
DOI: 10.6084/m9.figshare.c.3636047_d2.v1, https://springernature.figshare.com/articles/dataset/Additional_file_17_Table_S3_of_Integrative_analysis_of_the_Trypanosoma_brucei_gene_expression_cascade_predicts_differential_regulation_of_mRNA_processing_and_unusual_control_of_ribosomal_protein_expression/4440305/1
Dataset
-
Additional file 14: Table S2. of Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal protein expression
Antwi, E. (Contributor), Haanstra, J. (Contributor), Ramasamy, G. (Contributor), Jensen, B. (Contributor), Droll, D. (Contributor), Rojas, F. (Contributor), Minia, I. (Contributor), Terrao, M. (Contributor), Mercé, C. (Contributor), Matthews, K. (Contributor), Myler, P. (Contributor), Parsons, M. (Contributor) & Clayton, C. (Contributor), Unknown Publisher, 26 Apr 2016
DOI: 10.6084/m9.figshare.c.3636047_d3.v1, https://springernature.figshare.com/articles/dataset/Additional_file_14_Table_S2_of_Integrative_analysis_of_the_Trypanosoma_brucei_gene_expression_cascade_predicts_differential_regulation_of_mRNA_processing_and_unusual_control_of_ribosomal_protein_expression/4440308/1
Dataset
-
Additional file 3: of Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal protein expression
Antwi, E. (Contributor), Haanstra, J. (Contributor), Ramasamy, G. (Contributor), Jensen, B. (Contributor), Droll, D. (Contributor), Rojas, F. (Contributor), Minia, I. (Contributor), Terrao, M. (Contributor), MercĂŠ, C. (Contributor), Matthews, K. (Contributor), Myler, P. (Contributor), Parsons, M. (Contributor) & Clayton, C. (Contributor), Unknown Publisher, 26 Apr 2016
DOI: 10.6084/m9.figshare.c.3636047_d10.v1, https://springernature.figshare.com/articles/dataset/Additional_file_3_of_Integrative_analysis_of_the_Trypanosoma_brucei_gene_expression_cascade_predicts_differential_regulation_of_mRNA_processing_and_unusual_control_of_ribosomal_protein_expression/4440329/1
Dataset
-
Additional file 2: of Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal protein expression
Antwi, E. (Contributor), Haanstra, J. (Contributor), Ramasamy, G. (Contributor), Jensen, B. (Contributor), Droll, D. (Contributor), Rojas, F. (Contributor), Minia, I. (Contributor), Terrao, M. (Contributor), MercĂŠ, C. (Contributor), Matthews, K. (Contributor), Myler, P. (Contributor), Parsons, M. (Contributor) & Clayton, C. (Contributor), Unknown Publisher, 26 Apr 2016
DOI: 10.6084/m9.figshare.c.3636047_d6.v1, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Integrative_analysis_of_the_Trypanosoma_brucei_gene_expression_cascade_predicts_differential_regulation_of_mRNA_processing_and_unusual_control_of_ribosomal_protein_expression/4440317/1
Dataset