Research Output per year
Personal profile
Personal information
I am an enthusiastic and skilled systems biologist who can efficiently collaborate and communicate with researchers in various discipline”
In my research, I combine wetlab experiments with computational modelling to advance quantitative understanding of biological processes in healthy and disease cells. I have mainly applied this in metabolism and the gene expression cascade
Specialties: Metabolism, 'pathogens' in the context of the host environment (e.g. trypanosomes in the bloodstream, cancer cells amidst healthy cells), mathematical modeling, blood cells, tumerogenesis, mouse models
Research
Current projects
- ErasysApp IMOMESIC: This project aims to obtain systems understanding on how the integration of metabolism and signalling is altered in liver cancer cells compared to the healthy liver.
- Together with bachelor and master students, I have several computational and experimental projects on energy metabolism in parasites
Ancillary activities
- COST ACTION CM1307 | Amsterdam | Memberof the Management Committee for the Netherlands | 2015-03-02
- VVE Ravelijn | Utrecht | Bestuurder | 2015-04-01
Ancillary activities are updated daily
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 2002 2018
Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux
Bosdriesz, E., Wortel, M. T., Haanstra, J. R., Wagner, M. J., De La Torre Cortés, P. & Teusink, B. 3 Apr 2018 In : Scientific Reports. 8, 1, p. 1-9 9 p., 5576Research output: Scientific - peer-review › Article
Low affinity membrane transporters can increase net substrate uptake rate by reducing efflux
Bosdriesz, E., Wortel, M. T., Haanstra, J. R., Wagner, M., de la Torre Cortés, P. & Teusink, B. 2 Nov 2017 In : bioRxiv.Research output: Scientific › Article
Targeting pathogen metabolism without collateral damage to the host.
Haanstra, J. R., Gerding, A., Dolga, A. M., Sorgdrager, F. J., Buist-Homan, M., du Toit, F., Faber, K. N., Holzhutter, H. G., Szoor, B., Matthews, K. R., Snoep, J. L., Westerhoff, H. V. & Bakker, B. M. 2017 In : Scientific Reports. 7, 40406Research output: Scientific - peer-review › Article
Attacking Blood-Borne Parasites with Mathematics
van Niekerk, D. D., Penkler, G. P., du Toit, F., Snoep, J. L., Bakker, B. M. & Haanstra, J. R. 2016 Comprehensive Analysis of Parasite Biology: From Metabolism to Drug Discovery. Muller, S., Cerdan, R., Radulescu, O. & Selzer, P. (eds.). 1 ed. Wiley-VCH Verlag GmbH & Co. KGaA, Vol. 7, p. 513 541 p.Research output: Scientific › Chapter
Biogenesis, maintenance and dynamics of glycosomes in trypanosomatid parasites.
Haanstra, J. R., González-Marcano, E. B., Gualdrón-López, M. & Michels, P. A. 2016 In : Biochimica et Biophysica Acta. Molecular Cell Research. 1863, 5, p. 1038-1048Research output: Scientific - peer-review › Article