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Personal profile

Personal information

Academic Position

Professor of Methodology and Integrity

Amsterdam University Medical Centers | Department of Epidemiology and Biostatistics | Amsterdam Public Health research institute

Vrije Universiteit | Faculty of Humanities | Department of Philosophy


Short Biography

Lex Bouter was born in Rotterdam in 1956. After obtaining a MSc degree in Medical Biology at Utrecht University in 1982, he lectured at teacher training colleges in Tilburg and Utrecht. In 1984 he joined Maastricht University, where he was trained as an epidemiologist and obtained his PhD. In 1988 he published a textbook on epidemiology, the seventh revised Dutch edition of which appeared in 2016 and the first English edition in 2018.

In 1992 Bouter took up a tenured position as Professor of Epidemiology and became Scientific Director of the EMGO+ Institute for Health and Care Research at the VU University Medical Center in Amsterdam (1992-2006). He was Editor (1996-2002) and Editor-in-Chief (2002-2006) of the Cochrane Collaboration Back Review Group.

From 2001 until 2006 he additionally chaired of one of the six divisions at the VU University Medical Center. He was president of the Netherlands Epidemiological Society (1996-1997), member of the Health Council of the Netherlands (2001-2013), vice-chair and methodologist of the Dutch Central Committee on Research involving Human Subjects (2001-2013), and chair of the program committee of the Innovative Medical Devices Initiative (2009-2018) of Netherlands Organisation for Health Research and Development, and chair of the program committee for Replication Studies (since 2016) of the Netherlands Organization for Scientific Research.

From 2006 until 2013 he was Rector Magnificus and member of the Executive Board of Vrije Universiteit Amsterdam. In this function he focused on combining research groups in interdisciplinary research institutes. Also as rector Lex pleaded for attention for the societal impact of research. And he became interested in the dilemmas around scientific integrity.

Subsequently Lex prepared for a return to science during a sabbatical leave. In 2014 his tenured professorship was broadened to Methodology and Integrity. He is currently involved in teaching and research regarding responsible conduct of research, questionable research practices and research misconduct. In 2017 Bouter was appointed as member of the Council for Medical Research of the Royal Netherlands Academy of Arts and Sciences. In 2017 he organized and co-chaired the 5th World Conference on Research Integrity in Amsterdam and became chair of the World Conferences on Research Integrity Foundation.

Lex Bouter is author or co-author of 694 scientific publications contained in the Web of Science, which have been cited more than 54,000 times (WoS h-index of 118 and Google Scholar h-index of 160). He is listed among the 400 most influential biomedical researchers and has supervised 74 PhD students, of whom to date 15 were appointed as professor.

Ancillary activities

  • Netherlands Organization for Scientific Research (NWO) | Den Haag | Member of Commitee for Appeals | 2016-03-01
  • Royal Netherlands Society for Physiotherapy (KNGF) | Amersfoort | chairman of Scientific College Physiotherapy | 2016-03-01
  • Netherlands Organization for Scientific Research (NWO) | Den Haag | Chairman of Program Committee Replication Research | 2017-01-15
  • Royal Netherlands Academy for Arts and Sciences (KNAW) | Amsterdam | Member of the Council for Medical and Health Sciences | 2017-01-15
  • Federatie Medisch-Wetenschappelijke Verenigingen (FEDERA) | Rotterdam | Chair of Committee on Research Regulations | 2018-02-10
  • World Conferences on Research Integrity Foundation (WCRIF) | Amsterdam | Chair | 2018-02-10

Ancillary activities are updated daily

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Low Back Pain Medicine & Life Sciences
Randomized Controlled Trials Medicine & Life Sciences
Type 2 Diabetes Mellitus Medicine & Life Sciences
Glucose Medicine & Life Sciences
General Practice Medicine & Life Sciences
Netherlands Medicine & Life Sciences
Cohort Studies Medicine & Life Sciences
Population Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1983 2018

COSMIN guideline for systematic reviews of patient-reported outcome measures

Prinsen, C. A. C., Mokkink, L. B., Bouter, L. M., Alonso, J., Patrick, D. L., de Vet, H. C. W. & Terwee, C. B. 12 Feb 2018 In : Quality of Life Research.

Research output: Contribution to journalArticle

Open Access
Patient Reported Outcome Measures
Expert Testimony
Routine Diagnostic Tests

COSMIN methodology for evaluating the content validity of patient-reported outcome measures: a Delphi study

Terwee, C. B., Prinsen, C. A. C., Chiarotto, A., Westerman, M. J., Patrick, D. L., Alonso, J., Bouter, L. M., de Vet, H. C. W. & Mokkink, L. B. May 2018 In : Quality of Life Research. 27, 5, p. 1159-1170 12 p.

Research output: Contribution to journalReview article

Open Access
Delphi Technique
Sample Size
Patient Reported Outcome Measures

Determinants of selective reporting: A taxonomy based on content analysis of a random selection of the literature

van der Steen, J. T., van den Bogert, C. A., van Soest-Poortvliet, M. C., Fazeli Farsani, S., Otten, R. H. J., Ter Riet, G. & Bouter, L. M. 2018 In : PLoS One. 13, 2, p. e0188247

Research output: Contribution to journalArticle

Open Access
Selection Bias
Empirical Research
Open Access

Humanities need a replication drive too

Peels, R. & Bouter, L. 21 Jun 2018 In : Nature. 558, 7710, p. 372-372 1 p.

Research output: Contribution to journalLetter

Open Access