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Personal profile

Personal information

Academic Position

Professor of Methodology and Integrity

Amsterdam University Medical Centers | Department of Epidemiology and Biostatistics | Amsterdam Public Health research institute

Vrije Universiteit | Faculty of Humanities | Department of Philosophy


Short Biography

Lex Bouter was born in Rotterdam in 1956. After obtaining a MSc degree in Medical Biology at Utrecht University in 1982, he lectured at teacher training colleges in Tilburg and Utrecht. In 1984 he joined Maastricht University, where he was trained as an epidemiologist and obtained his PhD. In 1988 he published a textbook on epidemiology, the seventh revised Dutch edition of which appeared in 2016 and the first English edition in 2018.

In 1992 Bouter took up a tenured position as Professor of Epidemiology and became Scientific Director of the EMGO+ Institute for Health and Care Research at the VU University Medical Center in Amsterdam (1992-2006). He was Editor (1996-2002) and Editor-in-Chief (2002-2006) of the Cochrane Collaboration Back Review Group.

From 2001 until 2006 he additionally chaired of one of the six divisions at the VU University Medical Center. He was president of the Netherlands Epidemiological Society (1996-1997), member of the Health Council of the Netherlands (2001-2013), vice-chair and chief methodologist of the Dutch Central Committee on Research involving Human Subjects (2001-2013), and chair of the program committee of the Innovative Medical Devices Initiative (2009-2018) of Netherlands Organisation for Health Research and Development, and chair of the program committee for Replication Studies (since 2016) of the Netherlands Organization for Scientific Research.

From 2006 until 2013 he was Rector Magnificus of the Vrije Universiteit Amsterdam. In this function he focused on the formation of  interdisciplinary research institutes. As rector Lex pleaded for attention for the societal impact of research and became interested in the dilemmas around research integrity.

In 2014 his tenured professorship was broadened to Methodology and Integrity. He is currently involved in teaching and research regarding responsible conduct of research. In 2017 Bouter was appointed as member of the Council for Medical Research of the Royal Netherlands Academy of Arts and Sciences. In 2017 he organized and co-chaired the 5th World Conference on Research Integrity in Amsterdam and became chair of the World Conferences on Research Integrity Foundation.

Lex Bouter is author or co-author of 699 scientific publications contained in the Web of Science, which have been cited more than 57,000 times leading to a h-index of 120. In 2013 he was listed among the 400 most influential biomedical researchers and he has supervised 74 PhD students, of whom to date 15 were appointed as professor.

Ancillary activities

  • Netherlands Organization for Scientific Research (NWO) | Den Haag | Member of Commitee for Appeals | 2016-03-01 - present
  • Royal Netherlands Society for Physiotherapy (KNGF) | Amersfoort | chairman of Scientific College Physiotherapy | 2016-03-01 - present
  • Netherlands Organization for Scientific Research (NWO) | Den Haag | Chairman of Program Committee Replication Research | 2017-01-15 - present
  • Royal Netherlands Academy for Arts and Sciences (KNAW) | Amsterdam | Member of the Council for Medical and Health Sciences | 2017-01-15 - present
  • Federatie Medisch-Wetenschappelijke Verenigingen (FEDERA) | Rotterdam | Chair of Committee on Research Regulations | 2018-02-10 - present
  • World Conferences on Research Integrity Foundation (WCRIF) | Amsterdam | Chair | 2018-02-10 - present

Ancillary activities are updated daily

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Low Back Pain Medicine & Life Sciences
Randomized Controlled Trials Medicine & Life Sciences
Type 2 Diabetes Mellitus Medicine & Life Sciences
Glucose Medicine & Life Sciences
General Practice Medicine & Life Sciences
Netherlands Medicine & Life Sciences
Cohort Studies Medicine & Life Sciences
Population Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1983 2019

Citation bias in the literature on dietary trans fatty acids and serum cholesterol

Urlings, M. J. E., Duyx, B., Swaen, G. M. H., Bouter, L. M. & Zeegers, M. P. A., 1 Feb 2019, In : Journal of Clinical Epidemiology. 106, p. 88-97 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Trans Fatty Acids
Journal Impact Factor
Open Access
Research Personnel

COSMIN guideline for systematic reviews of patient-reported outcome measures

Prinsen, C. A. C., Mokkink, L. B., Bouter, L. M., Alonso, J., Patrick, D. L., de Vet, H. C. W. & Terwee, C. B., 1 May 2018, In : Quality of Life Research. 27, 5, p. 1147-1157 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Patient Reported Outcome Measures
Expert Testimony
Routine Diagnostic Tests

COSMIN methodology for evaluating the content validity of patient-reported outcome measures: a Delphi study

Terwee, C. B., Prinsen, C. A. C., Chiarotto, A., Westerman, M. J., Patrick, D. L., Alonso, J., Bouter, L. M., de Vet, H. C. W. & Mokkink, L. B., May 2018, In : Quality of Life Research. 27, 5, p. 1159-1170 12 p.

Research output: Contribution to JournalReview articleAcademicpeer-review

Open Access
Delphi Technique
Sample Size
Patient Reported Outcome Measures

Determinants of selective reporting: A taxonomy based on content analysis of a random selection of the literature

van der Steen, J. T., van den Bogert, C. A., van Soest-Poortvliet, M. C., Fazeli Farsani, S., Otten, R. H. J., Ter Riet, G. & Bouter, L. M., 2018, In : PLoS ONE. 13, 2, p. e0188247

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Selection Bias
Empirical Research

Activities 2014 2014

Professor of Methodology and Integrity

Bouter, L. M. (Participant)

Activity: Other