M.H. Siderius

dr.

19962019
If you made any changes in Pure these will be visible here soon.

Personal profile

Ancillary activities

No ancillary activities

Ancillary activities are updated daily

Fingerprint Dive into the research topics where M.H. Siderius is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Chemokine Receptors Medicine & Life Sciences
Yeast Chemical Compounds
Saccharomyces cerevisiae Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Phosphoric Diester Hydrolases Medicine & Life Sciences
Cell Wall Medicine & Life Sciences
Cytomegalovirus Medicine & Life Sciences
Cells Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1996 2019

Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors

de Heuvel, E., Singh, A. K., Edink, E., van der Meer, T., van der Woude, M., Sadek, P., Krell-Jørgensen, M. P., van den Bergh, T., Veerman, J., Caljon, G., Kalejaiye, T. D., Wijtmans, M., Maes, L., de Koning, H. P., Jan Sterk, G., Siderius, M., de Esch, I. J. P., Brown, D. G. & Leurs, R., 18 Jun 2019, In : Bioorganic and Medicinal Chemistry. p. 1-15 15 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Trypanosoma brucei brucei
Phosphoric Diester Hydrolases
Parasites
Cyclic Nucleotides
Cytotoxicity

Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2)

de Heuvel, E., Singh, A. K., Boronat, P., Kooistra, A. J., van der Meer, T., Sadek, P., Blaazer, A. R., Shaner, N. C., Bindels, D. S., Caljon, G., Maes, L., Sterk, G. J., Siderius, M., Oberholzer, M., de Esch, I. J. P., Brown, D. G. & Leurs, R., 15 Sep 2019, In : Bioorganic and Medicinal Chemistry. 27, 18, p. 4013-4029 17 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Phosphodiesterase Inhibitors
Parasites
African Trypanosomiasis
Trypanosoma brucei brucei
Trypanosomiasis

Discovery of novel Schistosoma mansoni PDE4A inhibitors as potential agents against schistosomiasis

Sebastián-Pérez, V., Schroeder, S., Munday, J. C., Van Der Meer, T., Zaldívar-Díez, J., Siderius, M., De Koning, H. P., Brown, D., Martínez, A., Campillo, N. E., Leurs, R. & Gil, C., 1 Jan 2019, In : Future Medicinal Chemistry. 11, 14, p. 1703-1720 18 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Schistosoma mansoni
Schistosomiasis
Phosphoric Diester Hydrolases
Small Molecule Libraries
Cyclic Nucleotides

Phenyldihydropyrazolones as Novel Lead Compounds Against Trypanosoma cruzi

Sijm, M., Siciliano De Araújo, J., Kunz, S., Schroeder, S., Edink, E., Orrling, K. M., Matheeussen, A., Van De Meer, T., Sadek, P., Custers, H., Cotillo, I., Martin, J. J., Siderius, M., Maes, L., Brown, D. G., De Nazaré Correia Soeiro, M., Sterk, G. J., De Esch, I. J. P. & Leurs, R., 10 Apr 2019, In : ACS Omega. 4, 4, p. 6585-6596 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Lead compounds
Phosphoric Diester Hydrolases
Pharmaceutical Preparations
Phosphodiesterase 4 Inhibitors
Enzyme inhibition

The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth

Heukers, R., Fan, T. S., de Wit, R. H., van Senten, J. R., de Groof, T. W. M., Bebelman, M. P., Lagerweij, T., Vieira, J., de Munnik, S. M., Smits-de Vries, L., van Offenbeek, J., Rahbar, A., van Hoorick, D., Söderberg-Naucler, C., Würdinger, T., Leurs, R., Siderius, M., Vischer, H. F. & Smit, M. J., 30 Apr 2018, In : Oncogene. 2018, p. 1-12 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Chemokine Receptors
Glioblastoma
Cytomegalovirus
Single-Domain Antibodies
Growth

Activities 1996 2001

  • 10 Lecture / Presentation

hyper-osmotic stress response and regulation of cell wall integrity

R. Alonso Monge (Speaker), E Real (Speaker), I Wojda (Speaker), J.P. Bebelman (Speaker), W.H. Mager (Speaker), M.H. Siderius (Speaker)
25 Aug 2001

Activity: Lecture / PresentationAcademic

the role of molecular chaperones in hyperosmolarity response in the yeast Saccharomyces cerevisiae

x xian (Speaker), m molanus (Speaker), W.H. Mager (Speaker), M.H. Siderius (Speaker), S.M. van der Vies (Speaker)
11 Jan 2001

Activity: Lecture / PresentationAcademic

hyper-osmotic stress response and regulation of cell wall integrity in Saccharomyces cerevisiae share common functional aspects

R. Alonso Monge (Speaker), E Real (Speaker), I Wojda (Speaker), J.P. Bebelman (Speaker), W.H. Mager (Speaker), M.H. Siderius (Speaker)
25 Aug 2001

Activity: Lecture / PresentationAcademic

Novel insights into the osmotic stress response of yeast

W.H. Mager (Speaker), M.H. Siderius (Speaker)
7 Nov 2001

Activity: Lecture / PresentationAcademic

Hyperosmotic stress and cell wall modulation in Saccharomyces cerevisiae

W.H. Mager (Speaker), M.H. Siderius (Speaker)
7 Nov 2001

Activity: Lecture / PresentationAcademic