If you made any changes in Pure these will be visible here soon.

Research Output 2012 2019

Filter
Article
2019

A Genetic Investigation of the Well-Being Spectrum

Baselmans, B. M. L., van de Weijer, M. P., Abdellaoui, A., Vink, J. M., Hottenga, J. J., Willemsen, G., Nivard, M. G., de Geus, E. J. C., Boomsma, D. I. & Bartels, M., 15 May 2019, In : Behavior Genetics. 49, 3, p. 286-297 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Phenotype
phenotype
Loneliness
Health
genetic correlation

A Potential Role for the STXBP5-AS1 Gene in Adult ADHD Symptoms

The EAGLE-ADHD Consortium, 18 Jan 2019, In : Behavior Genetics. p. 1-16 16 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Impulsive Behavior
Single Nucleotide Polymorphism
Meta-Analysis
signs and symptoms (animals and humans)
meta-analysis

Association of Whole-Genome and NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Abdellaoui, A., Dolan, C. V., Hottenga, J. J., Mbarek, H., Middeldorp, C. M., Nivard, M. G., Posthuma, D., Willemsen, G., Boomsma, D. I., de Geus, E. JC., W J H Penninx, B., Jansen, R. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jan 2019, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Major Depressive Disorder
Anisotropy
Genome
Radiation
Diffusion Tensor Imaging

Associations between Loneliness and Personality are Mostly Driven by a Genetic Association with Neuroticism

Abdellaoui, A., Chen, H-Y., Willemsen, G., Ehli, E. A., Davies, G. E., Verweij, K. J. H., Nivard, M. G., de Geus, E. J. C., Boomsma, D. I. & Cacioppo, J. T., Apr 2019, In : Journal of Personality. 87, 2, p. 386-397 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Loneliness
Personality
Monozygotic Twins
Neuroticism
Molecular Biology

Biological insights into multiple birth: genetic findings from UK Biobank

Mbarek, H., van de Weijer, M. P., van der Zee, M. D., Ip, H. F., Beck, J. J., Abdellaoui, A., Ehli, E. A., Davies, G. E., Baselmans, B. M. L., Nivard, M. G., Bartels, M., de Geus, E. J. & Boomsma, D. I., Jun 2019, In : European Journal of Human Genetics. 27, 6, p. 970-979 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Multiple Birth Offspring
Fertility
Dizygotic Twins
Genome-Wide Association Study
Mothers
Social Class
Netherlands
Individuality
United Kingdom
Problem Behavior

Een tweelingstudie naar indicatoren van genetische en culturele transmissie

van der Laan, C. M., vande Weijer, S. G. A., Nivard, M. G. & Boomsma, D. I., Apr 2019, In : Tijdschrift voor Criminologie. 2019, 2, p. 148-164 17 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Social Science Genetic Association Consortium, 23and Me Research Team, eQTLGen Consortium & International Cannabis Consortium, 1 Feb 2019, In : Nature Genetics. 51, 2, p. 245-257 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic Loci
Genome-Wide Association Study
Single Nucleotide Polymorphism
Computational Biology
Synaptic Transmission

Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

eQTLGen Consortium, 15 Jan 2019, In : eLife. 8, p. 1-40 40 p., e39856.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Genomics
Genes
Furin
Transport Vesicles
Peer Review

Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits

Grotzinger, A. D., Rhemtulla, M., de Vlaming, R., Ritchie, S. J., Mallard, T. T., Hill, W. D., Ip, H. F., Marioni, R. E., McIntosh, A. M., Deary, I. J., Koellinger, P. D., Harden, K. P., Nivard, M. G. & Tucker-Drob, E. M., 1 Mar 2019, In : Nature Human Behaviour.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-Wide Association Study
Single Nucleotide Polymorphism
Phenotype
Genetic Models
Psychiatry

Identification of common genetic risk variants for autism spectrum disorder

Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, BUPGEN, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23Andme Research Team, Mar 2019, In : Nature Genetics. 51, 3, p. 431-444 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-Wide Association Study
Phenotype
Sample Size
Meta-Analysis
Autism Spectrum Disorder

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 11 Jun 2019, In : Nature Communications. 10, p. 1-18 18 p., 2548.

Research output: Contribution to JournalArticleAcademicpeer-review

methylation
DNA Methylation
Fetal Blood
blood
Blood

Multivariate genome-wide analyses of the well-being spectrum

BIOS Consortium, Mar 2019, In : Nature Genetics. 51, 3, p. 445-451 7 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-Wide Association Study
Genome
Meta-Analysis
Interneurons
Computational Biology

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

EArly Genetics Lifecourse Epidemiology (EAGLE) consortium & Early Growth Genetics (EGG) Consortium, Mar 2019, In : European Journal of Epidemiology. 34, 3, p. 279-300

Research output: Contribution to JournalArticleAcademicpeer-review

Molecular Epidemiology
Sample Size
Genetic Research
Low Birth Weight Infant
Atopic Dermatitis
2018

A Meta-Analysis and Meta-Regression of Incidental Second Language Word Learning from Spoken Input

de Vos, J. F., Schriefers, H., Nivard, M. G. & Lemhöfer, K., Dec 2018, In : Language Learning. 68, 4, p. 906-941 36 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
regression
language
learning
learning success
science

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

Abdellaoui, A., Derks, E. M., Dolan, C. V., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Nivard, M. G., Peyrot, W. J., Posthuma, D., Uitterlinden, A. G., Van der Auwera, S., Visscher, P. M., Willemsen, G., Boomsma, D. I., de Geus, E. JC., Martin, N. G., W J H Penninx, B., Tiemeier, H. & Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, 2018, In : Communications biology. 1, p. 163

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Major Depressive Disorder
Bipolar Disorder
Psychiatry
Pedigree
Inborn Genetic Diseases

Association Between Population Density and Genetic Risk for Schizophrenia

Colodro-Conde, L., Couvy-Duchesne, B., Whitfield, J. B., Streit, F., Gordon, S., Kemper, K. E., Yengo, L., Zheng, Z., Trzaskowski, M., De Zeeuw, E. L., Nivard, M. G., Das, M., Neale, R. E., MacGregor, S., Olsen, C. M., Whiteman, D. C., Boomsma, D. I., Yang, J., Rietschel, M., McGrath, J. J. & 2 othersMedland, S. E. & Martin, N. G., 1 Sep 2018, In : JAMA Psychiatry. 75, 9, p. 901-910 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Population Genetics
Population Density
Schizophrenia
Netherlands
Social Class

Characterizing the Relation Between Expression QTLs and Complex Traits: Exploring the Role of Tissue Specificity

UK Brain Expression Consortium, Sep 2018, In : Behavior Genetics. 48, 5, p. 374-385 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Organ Specificity
Quantitative Trait Loci
quantitative trait loci
Genome-Wide Association Study
rheumatoid arthritis

Childhood aggression and the co-occurrence of behavioural and emotional problems: results across ages 3–16 years from multiple raters in six cohorts in the EU-ACTION project

Bartels, M., Hendriks, A., Mauri, M., Krapohl, E., Whipp, A., Bolhuis, K., Conde, L. C., Luningham, J., Fung Ip, H., Hagenbeek, F., Roetman, P., Gatej, R., Lamers, A., Nivard, M., van Dongen, J., Lu, Y., Middeldorp, C., van Beijsterveldt, T., Vermeiren, R., Hankemeijer, T. & 16 othersKluft, C., Medland, S., Lundström, S., Rose, R., Pulkkinen, L., Vuoksimaa, E., Korhonen, T., Martin, N. G., Lubke, G., Finkenauer, C., Fanos, V., Tiemeier, H., Lichtenstein, P., Plomin, R., Kaprio, J. & Boomsma, D. I., Sep 2018, In : European Child and Adolescent Psychiatry. 27, 9, p. 1105-1121 17 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Aggression
Psychopathology
Problem Behavior
Social Problems
Child Behavior

DNA methylation signatures of educational attainment

Dongen, J. V., Bonder, M. J., Dekkers, K. F., Nivard, M. G., Iterson, M. V., Willemsen, G., Beekman, M., Spek, A. V. D., Meurs, J. B. J. V., Franke, L., Heijmans, B. T., Duijn, C. M. V., Slagboom, P. E. & Boomsma, D. I., 23 Mar 2018, In : npj Science of Learning 2018 3:1. 3, p. 1-14 14 p., 7.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
DNA Methylation
Smoking
Methylation
Air Pollution
Brain

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium

Peyrot, W. J., Van der Auwera, S., Milaneschi, Y., Dolan, C. V., Madden, P. A. F., Sullivan, P. F., Strohmaier, J., Ripke, S., Rietschel, M., Nivard, M. G., Mullins, N., Montgomery, G. W., Henders, A. K., Heat, A. C., Fisher, H. L., Dunn, E. C., Byrne, E. M., Air, T. A., Baune, B. T., Breen, G. & 10 othersLevinson, D. F., Lewis, C. M., Martin, N. G., Nelson, E. N., Boomsma, D. I., Grabe, H. J., Wray, N. R., Penninx, B. W. J. H., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & Hottenga, J. J., 1 Jul 2018, In : Biological Psychiatry. 84, 2, p. 138-147

Research output: Contribution to JournalArticleAcademicpeer-review

Major Depressive Disorder
Genomics
Psychiatry
Meta-Analysis
Depression

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium (vol 84, pg 138, 2018)

Peyrot, W. J., Van der Auwera, S., Milaneschi, Y., Dolan, C. . V., Madden, P. A. F., Sullivan, P. F., Strohmaier, J., Ripke, S., Rietschel, M., Nivard, M. G., Mullins, N., Montgomery, G. W., Henders, A. K., Heat, A. C., Fisher, H. L., Dunn, E. C., Byrne, E. M., Air, T. A., Baune, B. T., Breen, G. & 8 othersLevinson, D. F., Lewis, C. M., Martin, N. G., Nelson, E. N., Boomsma, D. . I., Grabe, H. J., Wray, N. R. & Penninx, B. W. J. H., 1 Dec 2018, In : Biological Psychiatry. 84, 11, p. 857-857

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes

eQTLGen Consortium, 27 Jul 2018, In : Nature Communications. 9, 14 p., 2941.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
genome
Genome-Wide Association Study
Medical problems
Type 2 Diabetes Mellitus
Genes

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N. & 30 othersCastelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., DIrek, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Eriksson, N., Hottenga, J. J., Jansen, R., Mbarek, H., Middeldorp, C. M., Milaneschi, Y., Nivard, M. G., Posthuma, D., Smit, J. H., Willemsen, G., Boomsma, D. I. & Penninx, B. W. J. H., May 2018, In : Nature Genetics. 50, 5, p. 668-681 14 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genome-Wide Association Study
Depression
Schizophrenia
Major Depressive Disorder
Suicide

Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia

Bansal, V., Mitjans, M., Burik, C. A. P., Linnér, R. K., Okbay, A., Rietveld, C. A., Begemann, M., Bonn, S., Ripke, S., de Vlaming, R., Nivard, M. G., Ehrenreich, H. & Koellinger, P. D., 6 Aug 2018, In : Nature Communications. 9, 1, p. 1-12 12 p., 3078.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
schizophrenia
Genetic Heterogeneity
genome
Genome-Wide Association Study
Schizophrenia

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Generation Scotland & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 20 Dec 2018, In : PLoS ONE. 13, 12, p. 1-29 29 p., e0209160.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Major Depressive Disorder
Proxy
Genes
Genome
genome

GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia

23Andme Research Team, Sep 2018, In : Nature Neuroscience. 21, 9, p. 1161-1170 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Genetic Loci
Genome-Wide Association Study
Cannabis
Psychiatry
Schizophrenia

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

Qi, T., Wu, Y., Zeng, J., Zhang, F., Xue, A., Jiang, L., Zhu, Z., Kemper, K., Yengo, L., Zheng, Z., van Dongen, J. & eQTLGen Consortium, 1 Dec 2018, In : Nature Communications. 9, 1, 2282.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
genes
blood
brain
Brain
Blood

Predicting loneliness with polygenic scores of social, psychological and psychiatric traits

Abdellaoui, A., Nivard, M. G., Hottenga, J. J., Fedko, I., Verweij, K. J. H., Baselmans, B. M. L., Ehli, E. A., Davies, G. E., Bartels, M., Boomsma, D. I. & Cacioppo, J. T., Jul 2018, In : Genes, Brain and Behavior. 17, 6, p. 1-10 10 p., e12472.

Research output: Contribution to JournalArticleAcademicpeer-review

Community Psychiatry
Loneliness
Psychology
Mental Health
Schizophrenia

White matter hyperintensities and vascular risk factors in monozygotic twins

ten Kate, M., Sudre, C. H., den Braber, A., Konijnenberg, E., Nivard, M. G., Cardoso, M. J., Scheltens, P., Ourselin, S., Boomsma, D. I., Barkhof, F. & Visser, P. J., Jun 2018, In : Neurobiology of Aging. 66, June, p. 40-48 9 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Monozygotic Twins
Blood Vessels
White Matter
vascular factor
2017

Conditional eQTL analysis reveals allelic heterogeneity of gene expression

Jansen, R., Hottenga, J-J., Nivard, M. G., Abdellaoui, A., Laport, B., de Geus, E. J., Wright, F. A., Penninx, B. W. J. H. & Boomsma, D. I., 15 Apr 2017, In : Human Molecular Genetics. 26, 8, p. 1444-1451 8 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Quantitative Trait Loci
Gene Expression
Single Nucleotide Polymorphism
Genome-Wide Association Study
Genes

C-reactive protein upregulates the whole blood expression of CD59 - an integrative analysis

Lepik, K., Annilo, T., Kukuškina, V., Kisand, K., Kutalik, Z., Peterson, P., Peterson, H., eQTLGen Consortium, Boomsma, D. I., Nivard, M. G. & van Dongen, J., Sep 2017, In : PLoS Computational Biology. 13, 9, p. e1005766

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
C-reactive protein
C-Reactive Protein
Blood
Up-Regulation
blood

Genetic loci associated with heart rate variability and their effects on cardiac disease risk

Nolte, I. M., Munoz, M. L., Tragante, V., Amare, A. T., Jansen, R., Vaez, A., von der Heyde, B., Avery, C. L., Bis, J. C., Dierckx, B., van Dongen, J., Gogarten, S. M., Goyette, P., Hernesniemi, J., Huikari, V., Hwang, S-J., Jaju, D., Kerr, K. F., Kluttig, A., Krijthe, B. P. & 144 othersKumar, J., van der Laan, S. W., Lyytikäinen, L-P., Maihofer, A. X., Minassian, A., van der Most, P. J., Müller-Nurasyid, M., Nivard, M., Salvi, E., Stewart, J. D., Thayer, J. F., Verweij, N., Wong, A., Zabaneh, D., Zafarmand, M. H., Abdellaoui, A., Albarwani, S., Albert, C., Alonso, A., Ashar, F., Auvinen, J., Axelsson, T., Baker, D. G., de Bakker, P. I. W., Barcella, M., Bayoumi, R., Bieringa, R. J., Boomsma, D., Boucher, G., Britton, A. R., Christophersen, I., Dietrich, A., Ehret, G. B., Ellinor, P. T., Eskola, M., Felix, J. F., Floras, J. S., Franco, O. H., Friberg, P., Gademan, M. G. J., Geyer, M. A., Giedraitis, V., Hartman, C. A., Hemerich, D., Hofman, A., Hottenga, J-J., Huikuri, H., Hutri-Kähönen, N., Jouven, X., Junttila, J., Juonala, M., Kiviniemi, A. M., Kors, J. A., Kumari, M., Kuznetsova, T., Laurie, C. C., Lefrandt, J. D., Li, Y., Li, Y., Liao, D., Limacher, M. C., Lin, H. J., Lindgren, C. M., Lubitz, S. A., Mahajan, A., McKnight, B., Zu Schwabedissen, H. M., Milaneschi, Y., Mononen, N., Morris, A. P., Nalls, M. A., Navis, G., Neijts, M., Nikus, K., North, K. E., O'Connor, D. T., Ormel, J., Perz, S., Peters, A., Psaty, B. M., Raitakari, O. T., Risbrough, V. B., Sinner, M. F., Siscovick, D., Smit, J. H., Smith, N. L., Soliman, E. Z., Sotoodehnia, N., Staessen, J. A., Stein, P. K., Stilp, A. M., Stolarz-Skrzypek, K., Strauch, K., Sundström, J., Swenne, C. A., Syvänen, A-C., Tardif, J-C., Taylor, K. D., Teumer, A., Thornton, T. A., Tinker, L. E., Uitterlinden, A. G., van Setten, J., Voss, A., Waldenberger, M., Wilhelmsen, K. C., Willemsen, G., Wong, Q., Zhang, Z-M., Zonderman, A. B., Cusi, D., Evans, M. K., Greiser, H. K., van der Harst, P., Hassan, M., Ingelsson, E., Järvelin, M-R., Kääb, S., Kähönen, M., Kivimaki, M., Kooperberg, C., Kuh, D., Lehtimäki, T., Lind, L., Nievergelt, C. M., O'Donnell, C. J., Oldehinkel, A. J., Penninx, B., Reiner, A. P., Riese, H., Van Roon, A. M., Rioux, J. D., Rotter, J. I., Sofer, T., Stricker, B. H., Tiemeier, H., Vrijkotte, T. G. M., Asselbergs, F. W., Brundel, B. J. J. M., Heckbert, S. R., Whitsel, E. A., den Hoed, M., Snieder, H. & de Geus, E. J. C., 14 Jun 2017, In : Nature Communications. 8, p. 15805

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
heart rate
Genetic Loci
loci
Heart Diseases
Heart Rate

Genetic loci associated with heart rate variability and their effects on cardiac disease risk (vol 8, pg 15805, 2017)

Nolte, I. M., Munoz, M. L., Tragante, V., Amare, A. T., Jansen, R., Vaez, A., von der Heyde, B., Avery, C. L., Bis, J. C., Dierckx, B., van Dongen, J., Gogarten, S. M., Goyette, P., Hernesniemi, J., Huikari, V., Hwang, S-J., Jaju, D., Kerr, K. F., Kluttig, A., Krijthe, B. P. & 144 othersKumar, J., van der Laan, S. W., Lyytikainen, L-P., Maihofer, A. X., Minassian, A., van der Most, P. J., Mueller-Nurasyid, M., Nivard, M., Salvi, E., Stewart, J. D., Thayer, J. F., Verweij, N., Wong, A., Zabaneh, D., Zafarmand, M. H., Abdellaoui, A., Albarwani, S., Albert, C., Alonso, A., Ashar, F., Auvinen, J., Axelsson, T., Baker, D. G., de Bakker, P. I. W., Barcella, M., Bayoumi, R., Bieringa, R. J., Boomsma, D., Boucher, G., Britton, A. R., Christophersen, I., Dietrich, A., Ehret, G. B., Ellinor, P. T., Eskola, M., Felix, J. F., Floras, J. S., Franco, O. H., Friberg, P., Gademan, M. G. J., Geyer, M. A., Giedraitis, V., Hartman, C. A., Hemerich, D., Hofman, A., Hottenga, J-J., Huikuri, H., Hutri-Kahonen, N., Jouven, X., Junttila, J., Juonala, M., Kiviniemi, A. M., Kors, J. A., Kumari, M., Kuznetsova, T., Laurie, C. C., Lefrandt, J. D., Li, Y., Li, Y., Liao, D., Limacher, M. C., Lin, H. J., Lindgren, C. M., Lubitz, S. A., Mahajan, A., McKnight, B., zu Schwabedissen, H. M., Milaneschi, Y., Mononen, N., Morris, A. P., Nalls, M. A., Navis, G., Neijts, M., Nikus, K., North, K. E., O'Connor, D. T., Ormel, J., Perz, S., Peters, A., Psaty, B. M., Raitakari, O. T., Risbrough, V. B., Sinner, M. F., Siscovick, D., Smit, J. H., Smith, N. L., Soliman, E. Z., Sotoodehnia, N., Staessen, J. A., Stein, P. K., Stilp, A. M., Stolarz-Skrzypek, K., Strauch, K., Sundstrom, J., Swenne, C. A., Syvanen, A-C., Tardif, J-C., Taylor, K. D., Teumer, A., Thornton, T. A., Tinker, L. E., Uitterlinden, A. G., van Setten, J., Voss, A., Waldenberger, M., Wilhelmsen, K. C., Willemsen, G., Wong, Q., Zhang, Z-M., Zonderman, A. B., Cusi, D., Evans, M. K., Greiser, H. K., van der Harst, P., Hassan, M., Ingelsson, E., Jarvelin, M-R., Kaab, S., Kahonen, M., Kivimaki, M., Kooperberg, C., Kuh, D., Lehtimaki, T., Lind, L., Nievergelt, C. M., O'Donnell, C. J., Oldehinkel, A. J., Penninx, B., Reiner, A. P., Riese, H., van Roon, A. M., Rioux, J. D., Rotter, J. I., Sofer, T., Stricker, B. H., Tiemeier, H., Vrijkotte, T. G. M., Asselbergs, F. W., Brundel, B. J. J. M., Heckbert, S. R., Whitsel, E. A., den Hoed, M., Snieder, H. & de Geus, E. J. C., 2 Aug 2017, In : Nature Communications. 8

Research output: Contribution to JournalArticleAcademicpeer-review

Psychopathology
Psychiatry
Schizophrenia
Attention Deficit and Disruptive Behavior Disorders
Conduct Disorder
Open Access
behavior problems
heritability
Mothers
Genome-Wide Association Study
Child Behavior

Joint developmental trajectories of internalizing and externalizing disorders between childhood and adolescence

Nivard, M. G., Lubke, G. H., Dolan, C. V., Evans, D. M., St Pourcain, B., Munafò, M. R. & Middeldorp, C. M., 1 Aug 2017, In : Development and Psychopathology. 29, 3, p. 919-928 10 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Joints
Comorbidity
Diagnostic and Statistical Manual of Mental Disorders
Growth
Therapeutics
Open Access
Molecular Epidemiology
Psychopathology
Mothers
Fathers
Netherlands

Short communication: Genetic association between schizophrenia and cannabis use

Verweij, C. J. H., Abdellaoui, A., Nivard, M. G., Sainz Cort, A., Ligthart, R. S. L., Draisma, H. H. M., Minica, C. C., International Cannabis Consortium, Willemsen, G., Hottenga, J. J., Boomsma, D. I. & Vink, J. M., 1 Feb 2017, In : Drug and Alcohol Dependence. 171, p. 117-121 5 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Cannabis
Schizophrenia
Communication
Genes
Statistics

Smoking and caffeine consumption: a genetic analysis of their association

Treur, J. L., Taylor, A. E., Ware, J. J., Nivard, M. G., Neale, M. C., McMahon, G., Hottenga, J. J., Baselmans, B. M. L., Boomsma, D. I., Munafò, M. & Vink, J. M., 1 Jul 2017, In : Addiction Biology. 22, 4, p. 1090-1102

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Caffeine
Smoking
Coffee
Netherlands
Mendelian Randomization Analysis

The International Cannabis Consortium: What Did We Learn About The Genetics Of Cannabis Use

Verweij, K., Minica, C., Stringer, S., van der Most, P., Mbarek, H., Nivard, M., Abdellaoui, A., Hottenga, J-J., Martin, N., Boomsma, D., Gillespie, N., Derks, E. & Vink, J., 15 Aug 2017, In : European Neuropsychopharmacology. 27, p. S494-S495

Research output: Contribution to JournalArticleAcademicpeer-review

2016

A genome-wide approach to children's aggressive behavior: The EAGLE consortium

Pappa, I., St Pourcain, B., Benke, K. S., Cavadino, A., Hakulinen, C., Nivard, M. G., Nolte, I. M., Tiesler, C. M. T., Bakermans-Kranenburg, M. J., Davies, G. E., Evans, D. M., Geoffroy, M. C., Grallert, H., Blokhuis, M. M., Hudziak, J. J., Kemp, J. P., Keltikangas-Järvinen, L., McMahon, G., Mileva-Seitz, V. R., Motazedi, E. & 23 othersPower, C., Raitakari, O. T., Ring, S. M., Rivadeneira, F., Rodriguez, A., Scheet, P., Seppälä, I., Snieder, H., Standl, M., Thiering, E., Timpson, N. J., Veenstra, R., Velders, F. P., Whitehouse, A. J. O., Davey Smith, G., Heinrich, J., Hypponen, E., Lehtimäki, T., Middeldorp, C. M., Oldehinkel, A. J., Pennell, C. E., Boomsma, D. I. & Tiemeier, H., 2016, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 171, 5, p. 562-572

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Child Behavior
Genome
Single Nucleotide Polymorphism
Meta-Analysis
Chromosomes, Human, Pair 2

Connecting the dots, genome-wide association studies in substance use

International Cannabis Consortium, 2016, In : Molecular Psychiatry. 21, 6, p. 733-735

Research output: Contribution to JournalArticleAcademicpeer-review

Detection of gene-environment interaction in pedigree data using genome-wide genotypes

Nivard, M. G., Middeldorp, C. M., Lubke, G. H., Hottenga, J. J., Abdellaoui, A., Boomsma, D. I. & Dolan, C. V., 2016, In : European Journal of Human Genetics. 24, 12, p. 1803-1809

Research output: Contribution to JournalArticleAcademicpeer-review

Gene-Environment Interaction
Pedigree
Single Nucleotide Polymorphism
Body Mass Index
Genotype

Evidence for Gender-Dependent Genotype by Environment Interaction in Adult Depression

Molenaar, D., Middeldorp, C. M., Willemsen, G., Ligthart, R. S. L., Nivard, M. G. & Boomsma, D. I., 2016, In : Behavior Genetics. 46, 1, p. 59-71

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
gender
genotype
Genotype
Depression
phenotypic variation

Genetic and environmental influences interact with age and sex in shaping the human methylome

van Dongen, J., Nivard, M. G., Willemsen, G., Hottenga, J. J., Helmer, Q., Dolan, C. V., Ehli, E. A., Davies, G. E., van Iterson, M., Breeze, C. E., Beck, S., Pool, R., Suchiman, H. E. D., Jansen, R., van Meurs, J. B., Heijmans, B. T., Slagboom, P. E. & Boomsma, D. I., 2016, In : Nature Communications. 7, 11115, p. 1-13 11115.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
methylation
genome
Methylation
Genes
Genome

Genetics: From Molecule to Society

Nivard, M. G. & Boomsma, D. I., 21 Nov 2016, In : Current Biology. 26, 22, p. R1194-R1196

Research output: Contribution to JournalArticleAcademicpeer-review

household income
Genome-Wide Association Study
Polymorphism
Causality
genetic correlation

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.

Okbay, A., Baselmans, B. M. L., de Neve, J. E., Turley, P., Nivard, M. G., Fontana, M. A., Meddens, S. F. W., Karlsson Linnér, R., Rietveld, C. A., Derringer, J., de Vlaming, R., Minica, C. C., Hottenga, J. J., Vinkhuyzen, A. A. E., Boomsma, D. I., de Geus, E. J. C., Medland, S. E., Meyer, M. N., Pickrell, J. K., Esko, T. & 6 othersKrueger, R. F., Beauchamp, J., Koellinger, P. D., Benjamin, D. J., Bartels, M. & Cesarini, D., 2016, In : Nature Genetics. 48, 6, p. 624-633

Research output: Contribution to JournalArticleAcademicpeer-review

Genome
Depression
Phenotype
Genome-Wide Association Study
Sample Size

Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium

Stringer, S., Minică, C. C., Verweij, K. J. H., Mbarek, H., Bernard, M., Derringer, J., van Eijk, K. R., Isen, J. D., Loukola, A., Maciejewski, D. F., Mihailov, E., van der Most, P. J., Sánchez-Mora, C., Roos, L., Sherva, R., Walters, R., Ware, J. J., Abdellaoui, A., Bigdeli, T. B., Branje, S. J. T. & 60 othersBrown, S. A., Bruinenberg, M., Casas, M., Esko, T., Garcia-Martinez, I., Gordon, S. D. S., Harris, J. M., Hartman, C. A., Henders, A. K., Heath, A. C., Hickie, I. B., Hickman, M., Hopfer, C. J., Hottenga, J. J., Huizink, A. C., Irons, D. E., Kahn, R. S., Korhonen, T., Kranzler, H. R., Krauter, K., van Lier, P. A. C., Lubke, G. H., Madden, P. A. F., Mägi, R., McGue, M. K., Medland, S. E., Meeus, W. H. J., Miller, M. B., Montgomery, G. W., Nivard, M. G., Nolte, I. M., Oldehinkel, A. J., Pausova, Z., Qaiser, B., Quaye, L., Ramos-Quiroga, J. A., Richarte, V., Rose, R. J., Shin, J., Stallings, M. C., Stiby, A. I., Wall, T. L., Wright, M. J., Koot, H. M., Paus, T., Hewitt, J. K., Ribasés, M., Kaprio, J., Boks, M. P. M., Snieder, H., Spector, T., Munafò, M. R., Metspalu, A., Gelernter, J., Boomsma, D. I., Iacono, W. G., Martin, N. G., Gillespie, N. A., Derks, E. M. & Vink, J. M., 29 Mar 2016, In : Translational Psychiatry. 6, p. e769

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Genome-Wide Association Study
Cannabis
Single Nucleotide Polymorphism
Genome
Genes