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Michiel de Boer, PhD 
Vrije Universiteit Amsterdam, Faculty of Science

Department of Health Sciences, Section Methodology and Applied Statistics, Room U439
Boelelaan 1085, 1081 HV Amsterdam, The Netherlands
t. 00 31 (0)20 5986985 / m.r.de.boer@vu.nl / Office days Monday, Tuesday, & Friday


I study and teach research methodology and statistics primarily in the field of Health Sciences. My main interest lies in the use and misuse of research methods in general or those specifically related to the field of epidemiology. Examples include my work (in collaboration with others) on testing for baseline differences in randomized trials and on stepped wedge designs. In the near future I am starting a project on the reasons why we use null hypothesis significance testing in science and why we haven't switched to alternatives. In my work as program director of the MSc Health Sciences I focus on creating a culture of inclusion and shared responsibility of lecturers, student, alumni and work field with the aim of improving our program and increasign satisfaction of all stakeholders.



I studied Human Movement Sciences in Groningen, the Netherlands from 1993-1998 and started to work on my PhD at the VU medical Center Amsterdam in 2000. I received my PhD on 'Quality of life of visually impared eldery ' with honors in 2005.


I am Program Director of the MSc Health Sciences. For information about the program please send an e-mail to: masterhealthsciences.falw@vu.nl

I am the examinator for:
Advanced Statistics (MSc Health Sciences, period 2)
Methodologie I (Health and Life (Gezondheid en Leven), period 5)
I also teach in a number of other courses in the Bachelor programs Health Sciences (Gezondheidswetenschappen), Health and Life (Gezondheid en Leven) and Biomedical Sciences (Biomedische Wetenschappen). Finally I co-teach the course Basic Epidemiology for the EpidM Master.

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Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Randomized Controlled Trials Medicine & Life Sciences
Low Back Pain Medicine & Life Sciences
Musculoskeletal Manipulations Medicine & Life Sciences
Quality of Life Medicine & Life Sciences
Health Medicine & Life Sciences
Low Vision Medicine & Life Sciences
Mental Disorders Medicine & Life Sciences
Cohort Studies Medicine & Life Sciences

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Research Output 2004 2018

Analysing outcome variables with floor effects due to censoring: A simulation study with longitudinal trial data

Spriensma, A. S., Eekhout, I., De Boer, M. R., Luime, J. J., De Jong, P. H., Bahçecitapar, M. K., Heymans, M. W. & Twisk, J. W. R. Apr 2018 In : Epidemiology Biostatistics and Public Health. 15, 2, p. 1-9 9 p., e12850

Research output: Contribution to journalArticle

Longitudinal Studies
Randomized Controlled Trials
Linear Models

Health-related quality of life of people with HIV: An assessment of patient related factors and comparison with other chronic diseases

Engelhard, E. A. N., Smit, C., Van Dijk, P. R., Kuijper, T. M., Wermeling, P. R., Weel, A. E., De Boer, M. R., Brinkman, K., Geerlings, S. E. & Nieuwkerk, P. T. 2 Jan 2018 In : AIDS. 32, 1, p. 103-112 10 p.

Research output: Contribution to journalArticle

Chronic Disease
Quality of Life
Mental Health
Type 1 Diabetes Mellitus

Investigating daily fatigue scores during two-week offshore day shifts

Riethmeister, V., Bültmann, U., Gordijn, M., Brouwer, S. & de Boer, M. 1 Sep 2018 In : Applied Ergonomics. 71, p. 87-94 8 p.

Research output: Contribution to journalArticle

Manipulating the alpha level cannot cure significance testing

Trafimow, D. , Amrhein, V. , Areshenkoff, C. N. , Barrera-Causil, C. J. , Beh, E. J. , Bilgiç, Y. K. , Bono, R. , Bradley, M. T. , Briggs, W. M. , Cepeda-Freyre, H. A. , Chaigneau, S. E. , Ciocca, D. R. , Correa, J. C. , Cousineau, D. , de Boer, M. R. , Dhar, S. S. , Dolgov, I. , Gómez-Benito, J. , Grendar, M. , Grice, J. W. & 30 others Guerrero-Gimenez, M. E., Gutiérrez, A., Huedo-Medina, T. B., Jaffe, K., Janyan, A., Karimnezhad, A., Korner-Nievergelt, F., Kosugi, K., Lachmair, M., Ledesma, R. D., Limongi, R., Liuzza, M. T., Lombardo, R., Marks, M. J., Meinlschmidt, G., Nalborczyk, L., Nguyen, H. T., Ospina, R., Perezgonzalez, J. D., Pfister, R., Rahona, J. J., Rodríguez-Medina, D. A., Romão, X., Ruiz-Fernández, S., Suarez, I., Tegethoff, M., Tejo, M., van de Schoot, R., Vankov, I. I. & Velasco-Forero, S. 15 May 2018 In : Frontiers in Psychology. 9, MAY, 699

Research output: Contribution to journalArticle

Sample Size
Research Design

Passive imputation and parcel summaries are both valid to handle missing items in studies with many multi-item scales

Eekhout, I., de Vet, H. C. W., de Boer, M. R., Twisk, J. W. R. & Heymans, M. W. Apr 2018 In : Statistical methods in medical research. 27, 4, p. 1128-1140 13 p.

Research output: Contribution to journalArticle

Linear Models
Missing Data
Coefficient Estimates