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Oscar van Linden

dr.

20112016
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Databases Medicine & Life Sciences
Cyclohexanones Chemical Compounds
Phosphotransferases Medicine & Life Sciences
Dermatoglyphics Medicine & Life Sciences
Ligands Medicine & Life Sciences
Receptor Protein-Tyrosine Kinases Chemical Compounds
Isomers Chemical Compounds
Computer Simulation Medicine & Life Sciences

Research Output 2011 2016

  • 4 Article
  • 1 PhD Thesis - Research VU, graduation VU

KLIFS: a structural kinase-ligand interaction database.

Kooistra, A. J., Kanev, G. K., van Linden, O. P. J., Leurs, R., de Esch, I. J. P. & de Graaf, C., 2016, In : Nucleic Acids Research. 44, D1, p. D365-D371

Research output: Contribution to Journal › Article › Academic › peer-review

Open Access
Phosphotransferases
Databases
Ligands
Dermatoglyphics
Protein Kinases

Fragment-based drug design of small molecule EPHA4 kinase inhibitors

van Linden, O. P. J., 2013

Research output: PhD Thesis › PhD Thesis - Research VU, graduation VU › Academic

Open Access
File

KLIFS: a knowledge-based structural database to navigate kinase-ligand interaction space

van Linden, O. P. J., Kooistra, A. J., Leurs, R., de Esch, I. J. P. & de Graaf, C., 2013, In : Journal of Medicinal Chemistry. 57, 2, p. 249-277 29 p.

Research output: Contribution to Journal › Article › Academic › peer-review

Dermatoglyphics
Phosphotransferases
Databases
Ligands
Designer Drugs

Regiochemistry of the condensation of 2-aroyl-cyclohexanones and 2-cyanoacetamide: 13C-labeling studies and semi-empirical MO calculations

van Linden, O. P. J., Wijtmans, M., Roumen, L., Rotteveel, L., Leurs, R. & de Esch, I. J. P., 2012, In : Journal of Organic Chemistry. 77, p. 7355-7363

Research output: Contribution to Journal › Article › Academic › peer-review

Cyclohexanones
Isomers
Labeling
Tetrahydroisoquinolines
Condensation

Fragment-based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase

van Linden, O. P. J., Farenc, C., Zoutman, W. H., Hameetman, L., Wijtmans, M., Leurs, R., Tensen, C. P., Siegal, G. & de Esch, I. J. P., 2011, In : European Journal of Medicinal Chemistry. 47, p. 493-500

Research output: Contribution to Journal › Article › Academic › peer-review

Receptor Protein-Tyrosine Kinases
Computer Simulation
Amines
Molecules
Hinges