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Personal information

I am a senior scientist with a strong background in liquid-phase separation techniques hyphenated to mass spectrometry. I focus on the characterization of biomacromolecules. This means e.g. determining heterogeneity, getting insights in degradation processes, mapping intentional modifications, and studying interactions. In all this research the goal is to keep the protein intact from sample to detector, as this reduces data complexity and minimizes risk of introducing artefacts along the way. As studying these properties of intact proteins is not straightforward, I develop and apply the required advanced hyphenated analytics. All of this is done in the context of biopharmaceutical, clinical, and doping analysis, often in collaboration with companies and other university groups. 

Ancillary activities

  • Capillary electrophoresis user group | Amsterdam | Bestuurder | 2015-01-01 - present
  • Discussion group Separation methods for Polymers | Amsterdam | Bestuurslid | 2016-08-01 - present
  • F. Hoffman la Roche | Basel | Adviseur | 2018-04-01 - present
  • Section Analytical Chemistry | Amsterdam | Bestuurslid | 2018-11-01 - present

Ancillary activities are updated daily

Academic qualification

Analytical Chemistry, PhD, Utrecht University

Apr 2006Jun 2010

Award Date: 22 Dec 2010

Analytical Sciences, Master, Vrije Universiteit Amsterdam

Sep 2004Apr 2006

Applied Analytical Chemistry , Bachelor, Saxion University of Applied Sciences, Handelskade 75, 7417 DH Deventer

Sep 2000Sep 2004

Keywords

  • QD Chemistry
  • intact protein analsysis
  • liquid chromatography
  • capillary electrophoresis
  • mass spectrometry
  • hyphenation
  • proteoform characterization
  • biopharmaceuticals

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