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Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 3 Similar Profiles
Single-Domain Antibodies Medicine & Life Sciences
Epidermal Growth Factor Receptor Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Photosensitizing Agents Medicine & Life Sciences
Chemokine Receptors Medicine & Life Sciences
Photochemotherapy Medicine & Life Sciences
Endocytosis Medicine & Life Sciences
Antibodies Medicine & Life Sciences

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Research Output 2013 2018

Heterogeneity assessment of antibody-derived therapeutics at the intact and middle-up level by low-flow sheathless capillary electrophoresis-mass spectrometry

Haselberg, R., De Vijlder, T., Heukers, R., Smit, M. J., Romijn, E. P., Somsen, G. W. & Domínguez-Vega, E., 1 Jan 2018, (Accepted/In press) In : Analytica Chimica Acta. 1044, p. 181-190

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Capillary electrophoresis
Capillary Electrophoresis
low flow
Mass spectrometry

Nanobody-Fc constructs targeting chemokine receptor CXCR4 potently inhibit signaling and CXCR4-mediated HIV-entry and induce antibody effector functions

Bobkov, V., Zarca, A. M., Van Hout, A., Arimont, M., Doijen, J., Bialkowska, M., Toffoli, E., Klarenbeek, A., van der Woning, B., van der Vliet, H. J., Van Loy, T., de Haard, H., Schols, D., Heukers, R. & Smit, M. J., Dec 2018, In : Biochemical Pharmacology. 158, p. 413-424 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Single-Domain Antibodies
Chemokine Receptors

The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth

Heukers, R., Fan, T. S., de Wit, R. H., van Senten, J. R., de Groof, T. W. M., Bebelman, M. P., Lagerweij, T., Vieira, J., de Munnik, S. M., Smits-de Vries, L., van Offenbeek, J., Rahbar, A., van Hoorick, D., Söderberg-Naucler, C., Würdinger, T., Leurs, R., Siderius, M., Vischer, H. F. & Smit, M. J., 30 Apr 2018, In : Oncogene. 2018, p. 1-12 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Chemokine Receptors
Single-Domain Antibodies

EGFR targeted nanobody-photosensitizer conjugates for photodynamic therapy in a pre-clinical model of head and neck cancer

van Driel, P. B. A. A., Boonstra, M. C., Slooter, M. D., Heukers, R., Stammes, M. A., Snoeks, T. J. A., de Bruijn, H. S., van Diest, P. J., Vahrmeijer, A. L., van Bergen En Henegouwen, P. M. P., van de Velde, C. J. H., Löwik, C. W. G. M., Robinson, D. J. & Oliveira, S., 10 May 2016, In : Journal of Controlled Release. 229, p. 93-105 13 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Single-Domain Antibodies
Photosensitizing Agents
Head and Neck Neoplasms
Epidermal Growth Factor Receptor

Depleting MET-Expressing Tumor Cells by ADCC Provides a Therapeutic Advantage over Inhibiting HGF/MET Signaling

Hultberg, A., Morello, V., Huyghe, L., De Jonge, N., Blanchetot, C., Hanssens, V., De Boeck, G., Silence, K., Festjens, E., Heukers, R., Roux, B., Lamballe, F., Ginestier, C., Charafe-Jauffret, E., Maina, F., Brouckaert, P., Saunders, M., Thibault, A., Dreier, T., de Haard, H. & 1 othersMichieli, P., 15 Aug 2015, In : Cancer Research. 75, 16, p. 3373-83 11 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Neoplasm Antibodies
Hepatocyte Growth Factor