Personal profile

Ancillary activities

  • Stichting Farmacochemie Amsterdam | Amsterdam | Secretaris | 2013-12-16
  • Stichting Farmacochemische Congressen | Amsterdam | Secretaris | 2013-12-16
  • Griffin Discoveries BV | Amsterdam | Directeur | 2015-04-01

Last mutation Ancillary Activities: Amsterdam (2015-04-03)

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Research Output 1990 2017

3D-e-Chem-VM: Structural Cheminformatics Research Infrastructure in a Freely Available Virtual Machine

McGuire, R., Verhoeven, S., Vass, M., Vriend, G., De Esch, I. J. P., Lusher, S. J., Leurs, R., Ridder, L., Kooistra, A. J., Ritschel, T. & de Graaf, C. 27 Feb 2017 In : Journal of Chemical Information and Modeling. 57, 2, p. 115-121 7 p.

Research output: Scientific - peer-reviewArticle

Kinetics for Drug Discovery: an industry-driven effort to target drug residence time

Schuetz, D. A. , de Witte, W. E. A. , Wong, Y. C. , Knasmueller, B. , Richter, L. , Kokh, D. B. , Sadiq, S. K. , Bosma, R. , Nederpelt, I. , Heitman, L. H. , Segala, E. , Amaral, M. , Guo, D. , Andres, D. , Georgi, V. , Stoddart, L. A. , Hill, S. , Cooke, R. M. , de Graaf, C. , Leurs, R. & 6 others Frech, M., Wade, R. C., de Lange, E. C. M., IJzerman, A. P., Müller-Fahrnow, A. & Ecker, G. F. 1 Jun 2017 In : Drug Discovery Today. 22, 6, p. 896-911 16 p.

Research output: Scientific - peer-reviewReview article

Ligand-binding kinetics on histamine receptors

Bosma, R., Mocking, T. A. M., Leurs, R. & Vischer, H. F. 2017 Histamine receptors as drug targets. Humana Press, p. 115-155 (Methods in pharmacology and toxicology)

Research output: Scientific - peer-reviewChapter

Methods to study the molecular pharmacology of the histamine H4 receptor

Verweij, E. W. E., Leurs, R. & Vischer, H. F. 2017 Histamine receptors as drug targets. Humana Press, p. 157-181 (Methods in pharmacology and toxicology)

Research output: Scientific - peer-reviewChapter

Structural Analysis of Chemokine Receptor-Ligand Interactions

Arimont, M., Sun, S-L., Leurs, R., Smit, M., De Esch, I. J. P. & de Graaf, C. 22 Jun 2017 In : Journal of Medicinal Chemistry. 60, 12, p. 4735-4779 45 p.

Research output: Scientific - peer-reviewReview article