Raimond Heukers

dr.

20132019
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Fingerprint Dive into the research topics where Raimond Heukers is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Single-Domain Antibodies Medicine & Life Sciences
Epidermal Growth Factor Receptor Medicine & Life Sciences
Photosensitizing Agents Medicine & Life Sciences
Photochemotherapy Medicine & Life Sciences
G-Protein-Coupled Receptors Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Antibodies Medicine & Life Sciences
Chemokine Receptors Medicine & Life Sciences

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Research Output 2013 2019

Nanobodies: New avenues for imaging, stabilizing and modulating GPCRs

De Groof, T. W. M., Bobkov, V., Heukers, R. & Smit, M. J., 15 Mar 2019, In : Molecular and Cellular Endocrinology. 484, p. 15-24 10 p.

Research output: Contribution to JournalReview articleAcademicpeer-review

Open Access
Single-Domain Antibodies
G-Protein-Coupled Receptors
Imaging techniques
Immunoglobulin Fragments
Antibodies

Nanobodies detecting and modulating GPCRs outside in and inside out

Heukers, R., De Groof, T. W. M. & Smit, M. J., 1 Apr 2019, In : Current Opinion in Cell Biology. 57, p. 115-122 8 p.

Research output: Contribution to JournalReview articleAcademicpeer-review

Single-Domain Antibodies
G-Protein-Coupled Receptors
Immunoglobulin Fragments
Physiological Phenomena
Drug Discovery

Nanobody-Targeted Photodynamic Therapy Selectively Kills Viral GPCR-Expressing Glioblastoma Cells

De Groof, T. W. M., Mashayekhi, V., Fan, T. S., Bergkamp, N. D., Toraño, J. S., Van Senten, J. R., Heukers, R., Smit, M. J. & Oliveira, S., 1 Jan 2019, In : Molecular Pharmaceutics.

Research output: Contribution to JournalArticleAcademicpeer-review

Single-Domain Antibodies
Photochemotherapy
Viral Proteins
Glioblastoma
G-Protein-Coupled Receptors

Heterogeneity assessment of antibody-derived therapeutics at the intact and middle-up level by low-flow sheathless capillary electrophoresis-mass spectrometry

Haselberg, R., De Vijlder, T., Heukers, R., Smit, M. J., Romijn, E. P., Somsen, G. W. & Domínguez-Vega, E., 1 Jan 2018, (Accepted/In press) In : Analytica Chimica Acta. 1044, p. 181-190

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Capillary electrophoresis
Capillary Electrophoresis
low flow
antibody
Mass spectrometry

Nanobody-Fc constructs targeting chemokine receptor CXCR4 potently inhibit signaling and CXCR4-mediated HIV-entry and induce antibody effector functions

Bobkov, V., Zarca, A. M., Van Hout, A., Arimont, M., Doijen, J., Bialkowska, M., Toffoli, E., Klarenbeek, A., van der Woning, B., van der Vliet, H. J., Van Loy, T., de Haard, H., Schols, D., Heukers, R. & Smit, M. J., Dec 2018, In : Biochemical Pharmacology. 158, p. 413-424 12 p.

Research output: Contribution to JournalArticleAcademicpeer-review

Open Access
Single-Domain Antibodies
Chemokine Receptors
HIV
Antibodies
Molecules